Monitoring of Impurity Level of Valsartan and Hydrochlorothiazide Employing an RP–HPLC Gradient Mode

References

• Hillaert , S. , de Beer , T. R.M. , de Beer , J. O. and van den Bossche , W. 2003 . Optimization and validation of a micellar electrokinetic chromatographic method for the analysis of several angiotensin–II–receptor antagonists . J. Chromatogr. A , 984 ( 1 ) : 135 – 146 .
   PubMed Web of Science ®Google Scholar
• Hillaert , S. and van den Bossche , W. 2002 . Optimization and validation of a capillary zone electrophoretic method for the analysis of several angiotensin–II–receptor antagonists . J. Chromatogr. A , 979 ( 1–2 ) : 323 – 333 .
   PubMed Web of Science ®Google Scholar
• Hillaert , S. and van den Bossche , W. 2003 . Simultaneous determination of hydrochlorothiazide and several angiotensin–II–receptor antagonists by capillary electrophoresis . J. Pharm. Biomed. Anal. , 31 ( 2 ) : 329 – 339 .
   PubMed Web of Science ®Google Scholar
• Erk , N. 2002 . Spectrophotometric analysis of valsartan and hydrochlorothiazide . Anal. Lett. , 35 ( 2 ) : 283 – 302 .
   Web of Science ®Google Scholar
• Tatar , S. and Saglik , S. 2002 . Comparison of UV– and second derivative–spectrophotometric and LC methods for the determination of valsartan in pharmaceutical formulation . J. Pharm. Biomed. Anal. , 30 ( 2 ) : 371 – 375 .
   PubMed Web of Science ®Google Scholar
• Satana , E. , Altinay , S. , Goger , N. G. , Ozkan , S. A. and Senturk , Z. 2001 . Simultaneous determination of valsartan and hydrochlorothiazide in tablets by first–derivative ultraviolet spectrophotometry and LC . J. Pharm. Biomed. Anal. , 25 ( 5–6 ) : 1009 – 1013 .
   PubMed Web of Science ®Google Scholar
• Dinc , E. , Uslu , B. and Ozkan , S. A. 2004 . Spectral resolution of a binary mixture containing valsartan and hydrochlorothiazide in tablets by ratio spectra derivative and inverse least squares techniques . Anal. Lett. , 37 ( 4 ) : 679 – 693 .
   Web of Science ®Google Scholar
• Cagigal , E. , Gonzales , L. , Alonso , R. M. and Jimenez , R. M. 2001 . pKa determination of angiotensin–II–receptor antagonists by spectrofluorimetry . J. Pharm. Biomed. Anal. , 26 ( 3 ) : 477 – 486 .
   PubMed Web of Science ®Google Scholar
• Carlucci , G. , di Carlo , V. and Mazzeo , P. 2000 . Simultaneous determination of valsartan and hydrochlorothiazide in tablets by high–performance liquid chromatography . Anal. Lett. , 33 ( 12 ) : 2491 – 2500 .
   Web of Science ®Google Scholar
• Macek , J. , Klima , J. and Ptacek , P. 2006 . Rapid determination of valsartan in human plasma by protein precipitation and high performance liquid chromatography . J. Chrom. B , 832 ( 1 ) : 169 – 172 .
   PubMed Web of Science ®Google Scholar
• Daneshtalab , N. , Lewanczuk , R. Z. and Jamali , F. 2002 . High–performance liquid chromatographic analysis of angiotensin–II–receptor antagonist valsartan using a liquid extraction method . J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. , 766 ( 2 ) : 345 – 349 .
   PubMed Web of Science ®Google Scholar
• Gonzales , L. , Lopez , J. A. , Alonso , R. M. and Jimenez , R. M. 2002 . Fast screening method for the determination of angiotensin–II–receptor antagonists in human plasma by high–performance liquid chromatography with fluorimetric detection . J. Chromatogr. A. , 949 ( 1–2 ) : 49 – 60 .
   PubMed Web of Science ®Google Scholar
• Gonzales , L. , Alonso , R. M. and Jimenez , R. M. 2000 . High–performance liquid–chromatographic method for screening angiotensin–II–receptor antagonists in human urine . Chromatographia. , 52 ( 11–12 ) : 735 – 740 .
   Web of Science ®Google Scholar
• Cagigal , E. , Gonzales , L. , Alonso , R. M. and Jimenez , R. M. 2001 . Experimental design methodologies to optimise the spectrofluorimetric determination of losartan and valsartan in human urine . Talanta. , 54 ( 6 ) : 1121 – 1133 .
   PubMed Web of Science ®Google Scholar