Simultaneous Determination of Busulphan in Plasma Samples by Liquid Chromatography‐electrospray Ionization Mass Spectrometry Utilizing Microextraction in Packed Syringe (MEPS) as On‐line Sample Preparation Method

References

• Vassal , G. , Deroussent , A. , Hartmann , O. , Challine , D. , Benhamou , E. and Valteau‐Couanet , D. 1990 . Dose‐dependent neurotoxicity of high‐dose busulfan in children: A clinical and pharmacological study . Cancer Res. , 50 : 6203 – 6207 .
   PubMed Web of Science ®Google Scholar
• Bearman , S. I. 1995 . The syndrome of hepatic veno‐occlusive disease after marrow transplantation . Blood , 85 : 3005 – 3020 .
   PubMed Web of Science ®Google Scholar
• Hassan , M. , Ljungman , P. , Bolme , P. , Ringden , O. , Syruckova , Z. and Bekassy , A. 1994 . Busulfan bioavailability . Blood , 84 : 2144 – 2150 .
   PubMed Web of Science ®Google Scholar
• Hassan , M. , Oberg , G. , Bekassy , A. N. , Aschan , J. , Ehrsson , H. and Ljungman , P. 1991 . Pharmacokinetics of high‐dose busulphan in relation to age and chronopharmacology . Cancer Chemother. Pharmacol. , 28 : 130 – 134 .
   PubMed Web of Science ®Google Scholar
• Regazzi , M. B. , Locatelli , F. , Buggia , I. , Bonetti , F. , Zecca , M. and Pregnolato , M. 1993 . Disposition of high‐dose busulfan in pediatric patients undergoing bone marrow transplantation . Clin Pharmacol. Ther. , 54 : 45 – 52 .
   PubMed Web of Science ®Google Scholar
• Vassal , G. , Deroussent , A. , Challine , D. , Hartmann , O. , Koscielny , S. and Valteau‐Couanet , D. 1992 . Is 600 mg/m2 the appropriate dosage of busulfan in children undergoing bone marrow transplantation? . Blood , 79 : 2475 – 2479 .
   PubMed Web of Science ®Google Scholar
• Vassal , G. , Fischer , A. , Challine , D. , Boland , I. , Ledheist , F. and Lemerle , S. 1993 . Busulfan disposition below the age of three: Alteration in children with lysosomal storage disease . Blood , 82 : 1030 – 1034 .
   PubMed Web of Science ®Google Scholar
• Hassan , M. , Fasth , A. , Gerritsen , B. , Haraldsson , A. , Syruckova , Z. and van den Berg , H. 1996 . Busulphan kinetics and limited sampling model in children with leukemia and inherited disorders . Bone Marrow Transplant , 18 : 843 – 850 .
   PubMedGoogle Scholar
• Buggia , I. , Zecca , M. , Alessandrino , E. P. , Locatelli , F. , Rosti , G. and Bosi , A. 1996 . Itraconazole can increase systemic exposure to busulfan in patients given bone marrow transplantation. GITMO (Gruppo Italiano Trapianto di Midollo Osseo) . Anticancer Res. , 16 : 2083 – 2088 .
   PubMed Web of Science ®Google Scholar
• Slattery , J. T. , Sanders , J. E. , Buckner , C. D. , Schaffer , R. L. , Lambert , K. W. and Langer , F. P. 1995 . Graft‐rejection and toxicity following bone marrow transplantation in relation to busulfan pharmacokinetics [published erratum appears in Bone Marrow Transplant 1996 Oct, 18(4):829] . Bone Marrow Transplant , 16 : 31 – 42 .
   PubMed Web of Science ®Google Scholar
• Bolinger , A. M. , Zangwill , A. B. , Slattery , J. T. , Glidden , D. , DeSantes , K. and Heyn , L. 2000 . An evaluation of engraftment, toxicity and busulfan concentration in children receiving bone marrow transplantation for leukemia or genetic disease . Bone Marrow Transplant , 25 : 925 – 930 .
   PubMed Web of Science ®Google Scholar
• Slattery , J. T. , Clift , R. A. , Buckner , C. D. , Radich , J. , Storer , B. and Bensinger , W. I. 1997 . Marrow transplantation for chronic myeloid leukemia: The influence of plasma busulfan levels on the outcome of transplantation . Blood , 89 : 3055 – 3060 .
   PubMed Web of Science ®Google Scholar
• Grochow , L. B. 1993 . Busulfan disposition: The role of therapeutic monitoring in bone marrow transplantation induction regimens . Semin. Oncol. , 20 ( 4 Suppl 4 ) : 18 – 25 .
   PubMed Web of Science ®Google Scholar
• Dix , S. P. , Wingard , J. R. , Mullins , R. E. , Jerkunica , I. , Davidson , T. G. and Gilmore , C. E. 1996 . Association of busulfan area under the curve with veno‐occlusive disease following BMT . Bone Marrow Transplant , 17 : 225 – 230 .
   PubMed Web of Science ®Google Scholar
• Masson , E. and Zamboni , W. C. 1997 . Pharmacokinetic optimisation of cancer chemotherapy effect on outcomes . Clin. Pharmacokinet. , 32 : 324 – 343 .
   PubMed Web of Science ®Google Scholar
• McCune , J. S. , Gibbs , J. P. and Slattery , J. T. 2000 . Plasma concentration monitoring of busulfan: Does it improve clinical outcome? . Clin. Pharmacokinet. , 39 : 155 – 165 .
   PubMed Web of Science ®Google Scholar
• Chattergoon , D. S. , Saunders , E. F. , Klein , J. , Calderwood , S. , Doyle , J. and Freedman , M. H. 1997 . An improved limited sampling method for individualised busulphan dosing in bone marrow transplantation in children . Bone Marrow Transplant , 20 : 347 – 354 .
   PubMedGoogle Scholar
• Hassan , M. and Ehrsson , H. 1983 . Gas chromatographic determination of busulfan in plasma with electron‐capture detection . J. Chromatogr. , 277 : 374 – 380 .
   PubMed Web of Science ®Google Scholar
• Vassal , G. , Re , M. and Gouyette . 1988 . Gas chromatographic‐mass spectrometric assay for busulfan in biological fluids using a deuterated internal standard . J. Chromatogr. , 428 : 357 – 361 .
   PubMed Web of Science ®Google Scholar
• Quernin , M H. , Poonkuzhali , B. , Montes , C. , Krishnamoorthy , R. , Dennison , D. , Srivastava , A. , Vilmer , E. , Chandy , M. and Jacqz‐Aigrain , E. 1998 . Quantification of busulfan in plasma by gas chromatography‐mass spectrometry following derivatization with tetrafluorothiophenol . J. Chromatogr. B , 709 : 47 – 56 .
   PubMedGoogle Scholar
• Abdel‐Rehim , M. , Hassan , Z. , Blomberg , L. and Hassan , M. 2003 . On‐line derivatization utilizing solid‐phase microextraction (SPME) for determination of busulphan in plasma using gas chromatography‐mass spectrometry (GC‐MS) . Therapeutic Drug Monitoring , 25 : 400 – 406 .
   PubMedGoogle Scholar
• Oechtering , D. , Boos , J. , Hempel , G. J. and Chromatogr , B. 2006 . Monitoring of N,N‐dimethylacetamide in children during i.v.‐busulfan therapy by liquid chromatography‐mass spectrometry . 838 : 129 – 134 .
   Google Scholar
• Abdel‐Rehim , M. 2004 . New trends in sample preparation: Online microextraction in packed syringe for liquid and gas chromatography applications. I. Determination of local anaesthetics in human plasma samples using gas chromatography–mass spectrometry . J. Chromatogr. B. , 801 : 317 – 321 .
   PubMed Web of Science ®Google Scholar
• Abdel‐Rehim , M. , Altun , Z. and Blomberg , L. G. 2004 . Microextraction in packed syringe (MEPS) for liquid and gas chromatographic applications. Part II–Determination of ropivacaine and its metabolites in human plasma samples using MEPS with liquid chromatography/tandem mass spectrometry . J. Mass Spectrom. , 39 : 1488 – 1493 .
   PubMed Web of Science ®Google Scholar
• Vita , M. , Skansen , P. , Hassan , M. and Abdel‐Rehim , M. 2005 . Development and validation of a liquid chromatography and tandem mass spectrometry method for determination of roscovitine in plasma and urine samples utilizing on‐line sample preparation . J. Chromatogr. B. , 817 : 303 – 307 .
   PubMed Web of Science ®Google Scholar
• Abdel‐Rehim , M. , Altun , Z. , Jagerdeo , E. and Blomberg , L. 2006 . Drug screening using microextraction in packed syringe (MEPS)/LC‐MS utilizing monolithic‐based sorbent material . LCT&RT. , 29 : 829 – 839 .
   Google Scholar
• El‐Beqqali , A. , Kussak , A. and Abdel‐Rehim , M. 2006 . Fast and sensitive environmental analysis utilizing micro extraction in packed syringe online with gas chromatography–mass spectrometry: Determination of polycyclic aromatic hydrocarbons in water . J. Chromatogr. A. , 1114 : 234 – 238 .
   PubMed Web of Science ®Google Scholar
• Hassan , M. , Oberg , G. , Bjorkholm , M. , Wallin , I. and Lindgren , M. 1993 . Influence of prophylactic anticonvulsant therapy on high‐dose busulphan kinetics . Cancer Chemother. Pharmacol. , 33 : 81 – 86 .
   Google Scholar
• Shah , V. P. , Midha , K. K. , Findlay , J. W.A. , Hill , H. M. , Hulse , J. D. , McGilvery , I. J. , McKay , K. , Miller , K. J. , Patnaik , R. N. , Powell , M. L. , Tonelli , A. , Viswanathan , C. T. and Yacobi , A. 2000 . Analytical methods validation–A revisit with a decade of progress . Pharm. Research , 17 : 1551 – 1557 .
   PubMedGoogle Scholar