Determination of Ofloxacin Enantiomers in Pharmaceutical Formulations by Capillary Electrophoresis

References

• Fujimoto , T. and Mitsuhashi , S. 1990 . In vitro antibacterial activity of DR‐3355, the S‐(‐)‐isomer of ofloxacin . Chemotherapy , 36 : 268
   Google Scholar
• Hayakawa , I. , Atarashi , S. , Yokohama , S. , Imamura , M. , Sakano , K. and Furukawa , M. 1986 . Synthesis and antibacterial activities of optically active ofloxacin . Antimicrob. Agents Chemother. , 29 : 163 – 164 .
   PubMed Web of Science ®Google Scholar
• Sherrington , L. A. , Abba , M. , Hussain , B. and Donnelly , J. 2005 . The simultaneous separation and determination of five quinoline antibiotics using isocratic reversed‐phase HPLC: application to stability studies on an ofloxacin tablet formulation . J. Pharm. Biomed. Anal. , 39 : 769 – 775 .
   Google Scholar
• Lin , W.‐F. , Kang , X.‐H. , Chen , Z.‐G. , Yang , L. , Cai , P.‐X. and Mo , J.‐Y. 2005 . Content determination of ofloxacin and levofloxacin in their preparations by capillary electrohporesis . Chin. J. Antibiot. , 30 : 756 – 758 .
   Google Scholar
• Fierens , C. , Hillaert , S. and Bossche , W. V.D. 2002 . The qualitative and quantitative determination of quinolones of first and second generation by capillary electrophoresis . J. Pharm. Biomed. Anal. , 22 : 763 – 772 .
   Google Scholar
• Karl‐Heinz , L. and Damm , P. 1988 . Quantification of the enantiomers of ofloxacin in biological fluids by high‐performance liquid chromatography . J. Chromatogr. , 425 : 153 – 161 .
   Google Scholar
• Arai , T. , Koike , H. , Hirata , K. and Oizumi , H. 1988 . Separation of pyridone carboxylic acid enantiomers by high‐performance liquid chromatography using copper (II)‐L‐amino acid as the eluent . J. Chromatogr. A , 448 : 439 – 444 .
   Google Scholar
• Lehr , K. H. and Damm , P. 1988 . Quantification of the enantiomers of ofloxacin in biological fluids by high‐performance liquid chromatography . J. Chromatogr. A , 425 : 153 – 161 .
   PubMed Web of Science ®Google Scholar
• Blaschke , G. and Chankvetadze , B. 2000 . Enantiomer separation of drugs by capillary electromigration techniques . J. Chromatogr. A , 875 : 3 – 25 .
   PubMed Web of Science ®Google Scholar
• Altria , K. D. and Elder , D. 2004 . Overview of the status and applications of capillary electrophoresis to the analysis of small molecules . J. Chromatogr. A , 1023 : 1 – 14 .
   PubMed Web of Science ®Google Scholar
• Blanco , M. and Valverde , I. 2003 . Choice of chiral selector for enantioseparation by capillary electrophoresis . Trends Anal. Chem. , 22 : 428 – 439 .
   Google Scholar
• Chankevetadze , B. 2001 . Enantioseparation of chiral drugs and current status of electromigration techniques in this field . J. Sep. Sci. , 24 : 691 – 705 .
   Google Scholar
• Scriba , G. K.E. 2003 . Pharmaceutical and biomedical applications of chiral capillary electrophoresis and capillary electrochromatography: an update . Electrophoresis , 24 : 2409 – 2421 .
   PubMed Web of Science ®Google Scholar
• Fillet , M. , Chankvetadze , B. , Crommen , J. and Blaschke , G. 1999 . Designed combination of chiral selectors for adjustment of enantioseparation selectivity in capillary electrophoresis . Electrophoresis , 20 : 2691
   Google Scholar
• Fanali , S. 2000 . Enantioselective determination by capillary electrophoresis with cyclodextrins as chiral selectors . J. Chromatogr. A , 875 : 89 – 122 .
   PubMed Web of Science ®Google Scholar
• Koppenhoefer , B. , Epperlein , U. , Schlunk , R. , Zhu , X. and Lin , B. 1998 . Separation of enantiomers of drugs by capillary electrophoresis V. Hydroxypropyl‐α‐cyclodextrin as chiral solvating agent . J. Chromatogr. A , 793 : 153 – 164 .
   Google Scholar
• Zhou , S. , Ouyang , J. , Baeyyens , W. R.G. , Zhao , H. and Yang , Y. 2006 . Chiral separation of four fluoroquinlones compounds using capillary electrophoresis with hydroxypropyl‐β‐cyclodextrin as chiral selector . J. Chromatogr. A , 1130 : 296 – 301 .
   PubMed Web of Science ®Google Scholar
• Boer , T. D. , Mol , R. , Zeeuw , R. A.D. , Jong , G. J.D. and Ensing , K. 2001 . Enantioseparation of ofloxacin in urine by capillary electrokinetic chromatography using charged cyclodextrins as chiral selectors and assessment of enantioconversion . Electrophoresis , 22 : 1413 – 1418 .
   Google Scholar
• Wang , W. , Lu , J. , Fu , X. and Chen , Y. 2001 . Carboxymethyl‐β‐cyclodextrin for chiral separation of basic drugs by capillary electrophoresis . Anal. Lett. , 34 : 569 – 578 .
   Web of Science ®Google Scholar
• Arai , T. , Nimura , N. and Kinoshita , T. 1996 . Investigation of enantioselective separation of quinolonecarboxylic acids by capillary zone electrophoresis using vancomycin as a chiral selector . J. Chromatogr. A , 736 : 303 – 311 .
   Google Scholar
• Zhu , X. F. , Ding , Y. S. , Lin , B. C. , Jakob , A. and Koppenhoefer , B. 1999 . Study of enantioselective interactions between chiral drugs and serum by capillary electrophoresis . Electrophoresis , 20 : 1869 – 1877 .
   Google Scholar
• Arai , T. , Ichinose , M. , Kuroda , H. , Nimura , N. and Kinoshita , T. 1994 . Chiral separation by capillary affinity zone electrophoresis using an albumin‐containing support electrolyte . Anal. Biochem. , 217 : 7 – 11 .
   Google Scholar
• Horimai , T. , Ohara , M. and Ichinose , M. 1997 . Optical resolution of new quinoline drugs by capillary electrophoresis with ligand‐exchange and host‐guest interactions . J. Chromatogr. A , 760 : 235 – 244 .
   Web of Science ®Google Scholar
• Horstkötter , C. and Blaschke , G. 2001 . Stereoselective determination of ofloxacin and its metabolites in human urine by capillary electrophoresis using laser induced fluorescence detection . J. Chromatogr. B , 754 : 169 – 178 .
   PubMed Web of Science ®Google Scholar
• Awadallah , B. , Schmidt , P. C. and Wahl , M. A. 2003 . Quantitation of the enantiomers of ofloxacin by capillary electrophoresis in parts per billion concentration range for in vitro drug absorption studies . J. Chromatogr. A , 988 : 135 – 143 .
   PubMed Web of Science ®Google Scholar
• Maruszak , W. , Trojanowicz , M. , Margasinska , M. and Engelhardt , H. 2001 . Application of carboxymethyl‐β‐cyclodextrin as a chiral selector in capillary electrophoresis for enantiomers separation of selected neurotransmitters . J. Chromatogr. A , 926 : 327 – 336 .
   PubMed Web of Science ®Google Scholar
• Fillet , M. , Bechet , I. , Hubert , Ph. and Crommen , J. 1996 . Resolution improvement by use of carboxymethyl‐β‐cyclodextrins as chiral additive for the enantiomeric separation of basic drugs by capillary electrophoresis . J. Pharm. Biomed. Anal. , 14 : 1107 – 1114 .
   Google Scholar
• Zukowski , J. , Biasi , D. V. and Berthod , A. 2002 . Chiral separation of basic drugs by capillary electrophoresis with carboxymethylcyclodextrins . J. Chromatogr. A , 948 : 331 – 342 .
   PubMed Web of Science ®Google Scholar
• Sun , S.‐W. and Chen , L. Y. 1997 . Optimization of capillary electrophoretic separation of quinoline antibacterial using the overlapping resolution mapping scheme . J. Chromatogr. A , 766 : 215 – 224 .
   Web of Science ®Google Scholar
• Amini , A. 2001 . Recent developments in chiral capillary electrophoresis and applications of this technique to pharmaceutical and biomedical analysis . Electrophoresis , 22 : 3107 – 3130 .
   PubMed Web of Science ®Google Scholar
• Wren , S. A.C. and Rowe , R. C. 1992 . Theoretical aspects of chiral separation in capillary electrophoresis: I. Initial evaluation of a model . J. Chromatogr. , 603 : 235 – 241 .
   Web of Science ®Google Scholar
• Gubitz , G. and Schmid , M. G. 2000 . Recent advances in chiral separation principles in capillary electrophoresis and capillary electrochromatography . Electrophoresis , 21 : 4112 – 4133 .
   PubMedGoogle Scholar
• Melanson , J. E. , Baryla , N. E. and Lucy , C. A. 2001 . Dynamic capillary coatings electroosmotic flow control in capillary electrophoresis . Trends Anal. Chem. , 20 : 365 – 374 .
   Web of Science ®Google Scholar