SIMULTANEOUS DETERMINATION AND PHARMACOKINETIC COMPARISONS OF ALOE-EMODIN, RHEIN, EMODIN, AND CHRYSOPHANOL AFTER ORAL ADMINISTRATION OF THESE MONOMERS, RHEI RHIZOMA AND CHAIQIN-CHENGQI-TANG, TO RATS

REFERENCES

• Qin , F. ; Huang , X. ; Zhang , H. M. ; Ren , P. Pharmacokinetic Comparison of Puerarin After Oral Administration of Jiawei-Xiaoyao-San in Healthy Volunteers and Functional Dyspepsia Patients: Influence of Disease State . J. Pharm. Pharmacol. 2009 , 61 ( 1 ), 125 – 129 .
   PubMedGoogle Scholar
• Qin , F. ; Huang , X. ; Ren , P. Chinese Herbal Medicine Modified Xiaoyao San for Functional Dyspepsia: Meta-Analysis of Randomized Controlled Trials . J. Gastroenterol. Hepatol. 2009 , 24 ( 8 ), 1320 – 1325 .
   PubMed Web of Science ®Google Scholar
• Lu , T. ; Song , J. ; Huang , F. ; Deng , Y. ; Xie , L. ; Wang , G. ; Liu , X. Comparative Pharmacokinetics of Baicalin After Oral Administration of Pure Baicalin, Radix Scutellariae Extract and Huang-Lian-Jie-Du-Tang to Rats . J. Ethnopharmacol. 2007 , 110 ( 3 ), 412 – 418 .
   PubMed Web of Science ®Google Scholar
• Xu , M. ; Wang , G. ; Xie , H. ; Huang , Q. ; Wang , W. ; Jia , Y. Pharmacokinetic Comparisons of Schizandrin After Oral Administration of Schizandrin Monomer, Fructus Schisandrae Aqueous Extract and Sheng-Mai-San to Rats . j. Ethnopharmacol. 2008 , 115 ( 3 ), 483 – 488 .
   PubMedGoogle Scholar
• Ren , P. ; Qin , F. ; Huang , X. ; Zhu , Z. Simultaneous LC Analysis of Aloe-Emodin, Rhein, Emodin, and Chrysophanol in Rhizoma Rhei-Type Preparations . Chromatographia 2009 , 70 ( 9–10 ), 1515 – 1517 .
   Google Scholar
• Wang , Z. C. ; Xue , P. ; Huang , Z. W. Effect of an Early Application of Chaiqin Chengqi Decoction in Treating Severe Acute Pancreatitis Complicated with Acute Respiratory Distress Syndrome . Zhongguo Zhong Xi Yi Jie He Za Zhi 2009 , 29 ( 4 ), 322 – 324 .
   PubMedGoogle Scholar
• Chen , S. H. ; Lin , K. Y. ; Chang , C. C. ; Fang , C. L. ; Lin , C. P. Aloe-Emodin-Induced Apoptosis in Human Gastric Carcinoma Cells . Food Chem. Toxicol. 2007 , 45 ( 11 ), 2296 – 2303 .
   PubMed Web of Science ®Google Scholar
• Raimondi , F. ; Santoro , P. ; Maiuri , L. ; Londei , M. ; Annunziata , S. ; Ciccimarra , F. ; Rubino , A. Reactive Nitrogen Species Modulate the Effects of Rhein, an Active Component of Senna Laxatives, on Human Epithelium in vitro . J. Pediatr. Gastr. Nutr. 2002 , 34 ( 5 ), 529 – 534 .
   PubMed Web of Science ®Google Scholar
• Wang , C. F. ; Wu , X. D. ; Chen , M. ; Duan , W. G. ; Sun , L. X. ; Yan , M. ; Zhang , L. Y. Emodin Induces Apoptosis Through Caspase 3-Dependent Pathway in HK-2 Cells. Toxicology 2007, 231 (2–3), 120–128.
   PubMed Web of Science ®Google Scholar
• Lee , J. H. ; Kim , J. M. ; Kim , C. Pharmacokinetic Analysis of Rhein in Rheum Undulatum L . Journal of Ethnopharmacology 2003 , 84 ( 1 ), 5 – 9 .
   PubMed Web of Science ®Google Scholar
• Takizawa , Y. ; Morota , T. ; Takeda , S. ; Aburada , M. Pharmacokinetics of Rhein from Onpi-to, an Oriental Herbal Medicine, in Rats . Biol. Pharma. Bull. 2003 , 26 ( 5 ), 613 – 617 .
   PubMedGoogle Scholar
• Zaffaroni , M. ; Mucignat , C. ; Pecere , T. ; Zagotto , G. ; Frapolli , R. ; D'Incalci , M. ; Zucchetti , M. High-Performance Liquid Chromatographic Assay for the Determination of Aloe Emodin in Mouse Plasma . J. Chromatogr. B 2003 , 796 ( 1 ), 113 – 119 .
   PubMedGoogle Scholar
• Zhu , W. ; Wang , X. M. ; Zhang , L. ; Li , X. Y. ; Wang , B. X. Pharmacokinetic of Rhein in Healthy Male Volunteers Following Oral and Retention Enema Administration of Rhubarb Extract: A Single Dose Study . Amer. J. Chin. Med. 2005 , 33 ( 6 ), 839 – 850 .
   PubMedGoogle Scholar
• Tang , W. F. ; Huang , X. ; Yu , Q. ; Qin , F. ; Wan , M. H. ; Wang , Y. G. ; Liang , M. Z. ; Determination and Pharmacokinetic Comparison of Rhein in Rats After Oral Dosed with Da-Cheng-Qi Decoction and Xiao-Cheng-Qi Decoction . Biomed. Chromatogr. 2007 , 21 ( 11 ), 1186 – 1190 .
   PubMedGoogle Scholar
• Tang , W. ; Yu , Q. ; Wan , M. ; Qin , F. ; Chen , G. ; Liang , M. ; Huang , X. Simultaneous Determination and Pharmacokinetic Studies of Aloe Emodin and Chrysophanol in Rats After Oral Administration of Da-Cheng-Qi Decoction by High-Performance Liquid Chromatography . Biomed. Chromatogr. 2007 , 21 ( 7 ), 701 – 707 .
   PubMedGoogle Scholar
• Yan , D. ; Ma , Y. Simultaneous Quantification of Five Anthraquinones in Rat Plasma by High-Performance Liquid Chromatography with Fluorescence Detection . Biomed. Chromatogr. 2007 , 21 ( 5 ), 502 – 507 .
   PubMedGoogle Scholar
• Bachmann , M. ; Schlatter , C. Metabolism of [14C]emodin in the Rat . Xenobiotica 1981 , 11 ( 3 ), 217 – 225 .
   PubMed Web of Science ®Google Scholar
• Komatsu , K. ; Nagayama , Y. ; Tanaka , K. ; Kobayashi , N. Comparative Study of Chemical Constituents of Rhubarb from Different Origins . Chem. Pharm. Bull. 2006 , 54 ( 11 ), 1491 – 1499 .
   PubMedGoogle Scholar
• Koyama , J. ; Morita , I. ; Fujiyoshi , H. ; Kobayashi , N. Simultaneous Determination of Anthraquinones, Their 8-beta-D-glucosides, and Sennosides of Rhei Rhizoma by Capillary Electrophoresis . Chem. Pharm. Bull. 2005 , 53 ( 5 ), 573 – 575 .
   PubMedGoogle Scholar
• Fang , Y. S. ; Shan , D. M. ; Liu , J. W. ; Xu , W. ; Li , C. L. ; Wu , H. Z. ; Ji , G. Effect of Constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on Gastrointestinal Movement . Planta Medica 2009 , 75 ( 1 ), 24 – 31 .
   PubMedGoogle Scholar