A LC-MS/MS METHOD FOR THE DETERMINATION OF LUMEFANTRINE AND ITS METABOLITE DESBUTYL-LUMEFANTRINE IN PLASMA FROM PATIENTS INFECTED WITH PLASMODIUM FALCIPARUM MALARIA

REFERENCES

• César , I. C. ; Nogueira , F. H. A. ; Pianetti , G. A. Comparison of HPLC, UV Spectrophotometry and Potentiometric Titration Methods for the Determination of Lumefantrine in Pharmaceutical Products . J. Pharm. Biomed. Anal. 2008 , 48 , 223 – 226 .
   PubMed Web of Science ®Google Scholar
• White , N. J. ; van Vugt , M. ; Ezzet , F. Clinical Pharmacokinetics and Pharmacodynamics and Pharmacodynamics of Artemether-Lumefantrine . Clin. Pharmacokinet. 1999 , 37 , 105 – 125 .
   PubMed Web of Science ®Google Scholar
• Ezzet , F. ; Van Vugt , M. ; Nosten , F. ; Looareesuwan , S. ; White , N. J. Pharmacokinetics and Pharmacodynamics of Lumefantrine (Benflumetol) in Acute Falciparum Malaria . Antimicrob. Agents Chemother. 2000 , 44 , 697 – 704 .
   PubMed Web of Science ®Google Scholar
• Zeng , M. Y. ; Lu , Z. L. ; Yang , S. C. ; Zhang , M. ; Liao , J. ; Liu , S. L. ; Teng , X. H. Determination of Benflumetol in Human Plasma by Reversed-Phase High-Performance Liquid Chromatography with Ultraviolet Detection . J. Chromatogr. B 1996 , 681 , 299 – 306 .
   PubMed Web of Science ®Google Scholar
• Mansor , S. M. ; Navratnam , V. ; Yahaya , N. ; Nair , N. K. , Wernsdorfer , W. H. ; Degen , P. H. Determination of a New Antimalarial Drug, Benflumetol, in Blood Plasma by High-Performance Liquid Chromatography . J. Chromatogr. B 1996 , 682 , 321 – 325 .
   PubMedGoogle Scholar
• Annerberg , A. ; Singtoroj , T. ; Tipmanee , P. ; White , N. J. ; Day , N. P. J. ; Lindegårdh , N. High Throughput Assay for the Determination of Lumefantrine in Plasma . J. Chromatogr. B 2005 , 822 , 330 – 333 .
   PubMed Web of Science ®Google Scholar
• Lindegårdh , N. ; Annerberg , A. ; Blessborn , D. ; Bergqvist , Y. ; Day , N. ; White , N. J. Development and Validation of a Bioanalytical Method Using Automated Solid-Phase Extraction and LC-UV for the Simultaneous Determination of Lumefantrine and Its Desbutyl Metabolite in Plasma . J. Pharm. Biomed. Anal. 2005 , 37 , 1081 – 1088 .
   PubMed Web of Science ®Google Scholar
• Blessborn , D. ; Romsing , S. ; Annerberg , A. ; Sundquist , D. ; Bjorkman , A. ; Lindegårdh , N. ; Bergqvist , Y. Development and Validation of an Automated Solid-Phase Extraction and Liquid Chromatographic Method for Determination of Lumefantrine in Capillary Blood on Sampling Paper . J. Pharm. Biomed. Anal. 2007 , 45 , 282 – 287 .
   PubMed Web of Science ®Google Scholar
• Ntale , M. ; Ogwal-Okeng , J. W. ; Mahindi , M. ; Gustafsson , L. L. ; Beck , O. A Field-Adapted Sampling and HPLC Quantification Method for Lumefantrine and Its Desbutyl Metabolite in Whole Blood Spotted on Filter Paper . J. Chromatogr. B 2008 , 876 , 261 – 265 .
   PubMed Web of Science ®Google Scholar
• Wahajuddin , Singh , S. P. ; Jain , G. K. Determination of Lumefantrine in Rat Plasma by Liquid-Liquid Extraction Using LC-MS/MS with Electrospray Ionization: Assay Development, Validation and Application to a Pharmacokinetic Study . J. Chromatogr. B 2009 , 877 , 1133 – 1139 .
   PubMed Web of Science ®Google Scholar
• Hodel , E. M. ; Zanolari , B. ; Mercier , T. ; Biollaz , J. ; Keiser , J. ; Olliaro , P. ; Genton , B. ; Decosterd , L. A. A Single LC-Tandem Mass Spectrometry Method for the Simultaneous Determination of 14 Antimalarial Drugs and Their Metabolites in Human Plasma . J. Pharm. Biomed. Anal. 2009 , 877 , 867 – 886 .
   Google Scholar
• Hatz , C. ; Soto , J. ; Nothdurft , H. D. ; Zoller , T. ; Weitzel , T. ; Loutan , L. ; Bricaire , F. ; Gay , F. ; Burchard , G. D. ; Andriano , K. ; Lefevre , G. ; Palacios , P. I. D. ; Genton , B. Treatment of Acute Uncomplicated Falciparum Malaria with Artemether-Lumefantrine in Non-Immune Populations: A Safety, Efficacy, and Pharmacokinetic Study . Am. J. Trop. Med. Hyg. 2008 , 78 , 241 – 247 .
   PubMed Web of Science ®Google Scholar
• Noedl , H. ; Allmendinger , T. ; Prajakwong , S. ; Wernsdorfer , G. ; Wernsdorfer , W. H. Desbutyl-benflumetol, A Novel Antimalarial Compound: In vitro Activity in Fresh Isolates of Plasmodium falciparum from Thailand . Antimicrob. Agents Chemother. 2001 , 45 , 2106 – 2109 .
   PubMed Web of Science ®Google Scholar
• Matuszewski , B. K. Standard Line Slopes as a Measure of a Relative Matrix Effect in Quantitative HPLC-MS Bioanalysis . J. Chromatogr. B 2006 , 830 , 293 – 300 .
   PubMed Web of Science ®Google Scholar
• FDA, Guidance for Industry Bioanalytical Method Validation, Department of Health and Human Services; Food and Drug Administration: Rockville, USA, 2001; http:// www.fda.gov/cder/guidance/4252fnl.htm
   Google Scholar
• Bressolle , F. ; Bromet-Petit , M. ; Audran , M. Validation of Liquid Chromatographic and Gas Chromatographic Methods: Application to Pharmacokinetics . J. Chromatogr. B 1996 , 686 , 3 – 10 .
   PubMed Web of Science ®Google Scholar
• Ashley , E. A. ; Stepniewska , K. ; Lindegårdh , N. ; McGready , R. ; Annerberg , A. ; Hutagalung , R. ; Singtoroj , T. ; Hla , G. ; Brockman , A. ; Proux , S. ; Wilahphaingern , J. ; Singhasivanon , P. ; White , N. J. ; Nosten , F. Pharmacokinetic Study of Artemether-Lumefantrine Given Once Daily for the Treatment of Uncomplicated Multidrug-Resistant Falciparum Malaria . Trop. Med. Int. Health 2007 , 12 , 201 – 208 .
   PubMed Web of Science ®Google Scholar