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Original Articles

AN IMPROVED METHOD FOR THE EXTRACTION AND QUANTITATION OF DIOSGENIN IN TRIBULUS TERRESTRIS L.

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Pages 1141-1155 | Published online: 09 May 2012

REFERENCES

  • Chopra , R. N. ; Nayan , S. L. ; Chopra , I. C. Glossary of Indian Medicinal Plants , Council of Scientific and Industrial Research : New Delhi , 1956 .
  • Kostova , I. ; Dinchev , D. Saponin in Tribulus Terrestris – Chemistry and Bioactivity. Phytochem. Rev. 2005, 4, 111–137.
  • Gauthaman , K. ; Adaikan , P. G. ; Prasad , R. N. Aphrodisiac Properties of Tribulus terrestris Extract (Protodioscin) in Normal and Castrated Rats . Life. Sci. 2002 , 71 , 1385 – 1396 .
  • Neychev , V. K. ; Nikolova , E. ; Zhelev , N. ; Mitev , V. I. Saponins from Tribulus terrestris L are Less Toxic for Normal Human Fibroblasts than for Many Cancer Lines: Influence on Apoptosis and Proliferation . Exp. Biol. Med. 2007 , 232 , 126 – 133 .
  • Yang , H. J. ; Qu , W. J. ; Sun , B. Experimental study of saponins from tribulus terrestris on renal Carcinoma Cell Line. Zhongguo. Zhong. Yao. Za. Zhi. 2005 , 30 , 1271 – 1274 .
  • Sun , B. ; Qu , W. ; Bai , Z. The Inhibitory Effect of Saponins from Tribulus terrestris on Bcap-37 Breast Cancer Line. In Vitro. Zhong. Yao. Cai. 2003 , 26 , 104 – 106 .
  • Ali , M. A. ; Wahbi , S. ; Twaij , H. ; Badr , A. A. Tribulus terrestris : Preliminary Study of Its Diuretic and Contractile Effects and Comparison with Zea mays . J. Ethnopharmacol. 2003 , 85 , 257 – 260 .
  • Amin , A. ; Lotfy , M. ; Shafiullah , M. ; Adeghate , E. The Protective Effect of Tribulus terrestris in Diabetes . Ann. N.Y. Acad. Sci. 2006 , 1084 , 391 – 401 .
  • El-Tantawy , W. H. ; Hassanin , L. A. Hypoglycemic and Hypolipidemic Effects of Alcoholic Extract of Tribulus alatus in Streptozotocin-Induced Diabetic Rats: A Comparative Study with T. terrestris (Caltrop) . Indian J. Exp. Biol. 2007 , 45 , 785 – 790 .
  • Deepak , M. ; Dipankar , G. ; Prashanth , D. ; Asha , M. K. ; Amit , A. ; Venkataraman , B. V. Tribulosin and Beta-sitosterol-D-glucoside, the Anthelmintic Principles of Tribulus terrestris. Phytomedicine 2002 , 9 , 753 – 756 .
  • Al-Bayati , F. A. ; Al-Mola , H. F. Antibacterial and Antifungal Activities of Different Parts of Tribulus terrestris L. Growing in Iraq . J. Zhejiang. Univ. Sci. B. 2008 , 9 , 154 – 159 .
  • Wang , B. ; Ma , L. ; Liu , T. 406 Cases of Angina Pectoris in Coronary Heart Disease Treated with Saponin of Tribulus terrestris . Zhong. Xi. Yi. Jie. He. Za. Zhi. 1990 , 10 , 85 – 87 .
  • Guo , Y. ; Yin , H. J. ; Shi , D. Z. ; Chen , K. J. Effects of Tribuli Saponins on Left Ventricular Remodeling After Acute Myocardial Infarction in Rats with Hyperlipidemia . Chin. J. Integr. Med. 2005 , 11 , 142 – 146 .
  • Sharifi , A. M. ; Darabi , R. ; Akbarloo , N. Study of Antihypertensive Mechanism of Tribulus terrestris in 2K1C Hypertensive Rats: Role of Tissue ACE Activity . Life. Sci. 2003 , 73 , 2963 – 2971 .
  • Yan , W. ; Ohtani , K. ; Kasai , R. ; Yamasaki , K. Steroidal Saponins from Fruits of Tribulus terrestris . Phytochemistry 1996 , 42 , 1417 – 1422 .
  • Cai , L. ; Wu , Y. ; Zhang , J. ; Pei , F. ; Xu , Y. ; Xie , S. ; Xu , D. Steroidal Saponins from Tribulus terrestris . Planta. Med. 2001 , 67 , 196 – 198 .
  • Liu , T. ; Lu , X. ; Wu , B. ; Chen , G. ; Hua , H. M. ; Pei , Y. H. Two New Steroidal Saponins from Tribulus terrestris L . J. Asian. Nat. Prod. Res. 2010 , 12 , 30 – 35 .
  • Saleh , N. A. M. ; Ahmed , A. A. ; Abdalla , M. F. Flavonoid Glycosides of Tribulus pentandrus and Tribulus terrestris . Phytochemistry 1982 , 21 , 1995 – 2000 .
  • Wu , T. ; Shi , L. ; Kuo , S. Alkaloids and Other Constituents from Tribulus terrestris . Phytochemistry 1999 , 50 , 1411 – 1415 .
  • Li , J. X. ; Shi , Q. ; Xiong , Q. B. ; Prasain , J. K. ; Tezuka , Y. ; Hareyama , T. ; Wang , Z. T. ; Tanaka , K. ; Namba , T. ; Kadota , S. Tribulusamide A and B, New Hepatoprotective Lignanamides from the Fruits of Tribulus terrestris: Indications of Cytoprotective Activity in Murine Hepatocyte Culture . Planta. Med. 1998 , 64 , 628 – 631 .
  • Ren , Y. J. ; Chen , H. S. ; Yang , G. J. ; Zhu , H. Isolation and Identification of a New Derivative of Cinnamic Amide from Tribulus terrestris . Acta. Pharm. Sin. 1994 , 29 , 204 – 206 .
  • Jung , D. H. ; Park , H. J. ; Byun , H. E. ; Park , Y. M. ; Kim , T. W. ; Kim , B. O. ; Um , S. H. ; Pyo , S. Diosgenin Inhibits Macrophage-Derived Inflammatory Mediators through Down Regulation of CK2, JNK, NF-kappaB and AP-1 Activation . Immunopharmacology 2010 , 10 , 1047 – 1054 .
  • Hirai , S. ; Uemura , T. ; Mizoguchi , N. ; Lee , J. Y. ; Taketani , K. ; Nakano , Y. ; Hoshino , S. ; Tsuge , N. ; Narukami , T. ; Yu , R. ; Takahashi , N. ; Kawada , T. Diosgenin Attenuates Inflammatory Changes in the Interaction Between Adipocytes and Macrophages . Mol. Nutr. Food. Res. 2010 , 54 , 797 – 804 .
  • Liagre , B. ; Vergne-Salle , P. ; Corbiere , C. ; Charissoux , J. L. ; Beneytout , J. L. Diosgenin, a Plant Steroid, Induces Apoptosis in Human Rheumatoid Arthritis Synoviocytes with Cyclooxygenase-2 overexpression . Arthritis. Res. Ther. 2004 , 6 , R 373 – 383 .
  • Gong , G. ; Qin , Y. ; Huang , W. ; Zhou , S. ; Wu , X. ; Yang , X. ; Zhao , Y. ; Li , D. Protective Effects of Diosgenin in the Hyperlipidemic Rat Model and in Human Vascular Endothelial Cells Against Hydrogen Peroxide-Induced Apoptosis. Chem. Biol. Interact. 2010, 184, 366–375.
  • Lepage , C. ; Liagre , B. ; Cook-Moreau , J. ; Pinon , A. ; Beneytout , J. L. Cyclooxygenase-2 and 5-lipoxygenase Pathways in Diosgenin-Induced Apoptosis in HT-29 and HCT-116 Colon Cancer Cells . Int. J. Oncol. 2010 , 36 , 1183 – 1191 .
  • Li , F. ; Fernandez , P. P. ; Rajendran , P. ; Hui , K. M. ; Sethi , G. Diosgenin, a Steroidal Saponin, Inhibits STAT3 Signaling Pathway Leading to Suppression of Proliferation and Chemosensitization of Human Hepatocellular Carcinoma Cells . Cancer. Lett. 2010 , 292 , 197 – 207 .
  • Tada , Y. ; Kanda , N. ; Haratake , A. ; Tobiishi , M. ; Uchiwa , H. ; Watanabe , S. Novel Effect of Diosgenin On Skin Aging . Steroids 2009 , 74 , 504 – 511 .
  • Wei , J. ; Dong , X. Determination of Diosgenin in Rhizoma Paridis by High Performance Liquid Chromatography . Se Pu 1999 , 17 , 498 – 499 .
  • Niño , J. ; Jiménez , D. A. ; Mosquera , O. M. ; Correa , Y. M. Diosgenin Quantification by HPLC in a Dioscorea polygonoides Tuber Collection from Colombian Flora . J. Braz. Chem. Soc. 2007 , 18 , 1073 – 1076 .
  • Trivedi , P. D. ; Pundarikakshudu , K. ; Rathnam , S. ; Shah , K. S. A Validated Quantitative Thin-Layer Chromatographic Method for Estimation of Diosgenin in Various Plant Samples, Extract, and Market Formulation . J. AOAC. Int. 2007 , 90 , 358 – 363 .
  • Kabanov , V. S. ; Stikhin , V. A. ; Azarkova , A. F. Gas-Chromatographic Method for the Determination of Diosgenin . Pharm. Chem. J. 1980 , 14 , 268 – 272 .
  • Taylor , W. G. ; Elder , J. L. ; Chang , P. R. ; Richards , K. W. Microdetermination of Diosgenin from Fenugreek (Trigonella foenum-graecum) Seeds . J. Agric. Food. Chem. 2000 , 48 , 5206 – 5210 .
  • Xu , L. ; Liu , Y. ; Wang , T. ; Qi , Y. ; Han , X. ; Xu , Y. ; Peng , J. ; Tang , X. Development and Validation of a Sensitive and Rapid Non-Aqueous LC–ESI-MS/MS Method for measurement of Diosgenin in the Plasma of Normal and Hyperlipidemic Rats: A Comparative Study . J. Chromato. B 2009 , 877 , 1530 – 1536 .
  • Sofowora , E. A. ; Hardman , R. Chromatographic Detection and Spectrophotometric Determination of Diosgenin and Other Delta5-sapogenins in Crude Plant Extracts . Planta. Med. 1974 , 26 , 385 – 390 .
  • Rishi , A. K. ; Kapoor , R. ; Vakhlu , V. K. A Rapid Spectrophotometric Method for the Quantitative Determination of Diosgenin in Dioscorea Tubers . Curr. Sci. 1976 , 45 , 327 – 328 .
  • Li , T. ; Zhang , Z. ; Zhang , L. ; Huang , X. ; Lin , J. ; Chen , G. An Improved Facile Method for Extraction and Determination of Steroidal Saponins in Tribulus terrestris by Focused Microwave-Assisted Extraction Coupled with GC-MS . J. Sep. Sci. 2009 , 32 , 4167 – 4175 .

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