A new HPLC–MS/MS method for investigating degradation kinetics of 6‴-feruloylspinosin and identifying its metabolites by rat intestinal bacterial flora in vitro

References

• Pharmacopoeia of People’s Republic of China, Ed. State Pharmacopoeia Committee. Beijing: China Medical Pharmaceutical Science and Technology Publishing House, 2015, 343 p.
   Google Scholar
• Han, H.; Ma, Y.; Eun, J. S.; Li, R.; Hong, J. T.; Lee, M. K.; Oh, K. W. Anxiolytic-Like Effects of Sanjoinine A Isolated from Zizyphi Spinosi Semen: Possible Involvement of GABAergic Transmission. Pharmacol. Biochem. Behav. 2009, 92(2), 206–213.
   PubMed Web of Science ®Google Scholar
• Ma, Y.; Han, H.; Nam, S. Y.; Kim, Y. B.; Hong, J. T.; Yun, Y. P.; Oh, K. W. Cyclopeptide Alkaloid Fraction from Zizyphi Spinosi Semen Enhances Pentobarbital-Induced Sleeping Behaviors. J. Ethnopharmacol. 2008, 117(2), 318–324.
   PubMed Web of Science ®Google Scholar
• You, Z. L.; Xia, Q.; Liang, F. R.; Tang, Y. J.; Xu, C. L.; Huang, J.; Zhao, L.; Zhang, W. Z.; He, J. J. Effects on the Expression of GABAA Receptor Subunits by Jujuboside A Treatment in Rat Hippocampal Neurons. J. Ethnopharmacol. 2010, 128(2), 419–423.
   PubMed Web of Science ®Google Scholar
• Zhang, Y. Q.; Qiao, L. D.; Song, M. Y.; Wang, L. J.; Xie, J. B.; Feng, H. HPLC-ESI-MS/MS Analysis of the Water-Soluble Extract from Ziziphi Spinosae Semen and its Ameliorating Effect of Learning and Memory Performance in Mice. Pharmacogn. Mag. 2014, 10(40), 509–516.
   PubMed Web of Science ®Google Scholar
• Xie, J. B.; Zhang, Y. Q.; Wang, L. J.; Qi, W. Q.; Zhang, M. C. Composition of Fatty Oils from Semen Ziziphi Spinosae and its Cardiotonic Effect on Isolated Toad Hearts. Nat. Prod. Res. 2012, 26(5), 479–483.
   PubMed Web of Science ®Google Scholar
• Jiang, J. G.; Huang, X. J.; Chen, J.; Lin, Q. S. Comparison of the Sedative and Hypnotic Effects of Flavonoids: Saponins, and Polysaccharides Extracted from Semen Ziziphus jujube. Nat. Prod. Res. 2007, 21(4), 310–320.
   PubMed Web of Science ®Google Scholar
• Liu, J.; Chen, B.; Yao, S. Simultaneous Analysis and Identification of Main Bioactive Constituents in Extract of Zizyphus jujuba var sapinosa (Zizyphi Spinosi Semen) by High-Performance Liquid Chromatography-Photodiode Array Detection-Electrospray Mass Spectrometry. Talanta 2007, 71(2), 668–675.
   PubMed Web of Science ®Google Scholar
• Cheng, G.; Bai, Y.; Zhao, Y.; Tao, J.; Liu, Y.; Tu, G. Z.; Ma, L.; Liao, N.; Xu, X. J. Flavonoids from Ziziphus jujuba Mill var. spinosa. Tetrahedron 2000, 56(45), 8915–8920.
   Web of Science ®Google Scholar
• Mosele, J. I.; Macià, A.; Farràs, M.; Valls, R. M.; Catalán, U.; Motilva, M. J. Faecal Microbial Metabolism of Olive Oil Phenolic Compounds: In Vitro and In Vivo Approaches. Mol. Nutr. Food. Res. 2014, 58(9), 1809–1819.
   PubMed Web of Science ®Google Scholar
• Wang, J. R.; Yau, L. F.; Zhang, R.; Xia, Y.; Ma, J.; Ho, H. M.; Hu, P.; Hu, M.; Liu, L.; Jiang, Z. H. Transformation of Ginsenosides from Notoginseng by Artificial Gastric Juice can Increase Cytotoxicity Toward Cancer Cells. J. Agric. Food Chem. 2014, 62(12), 2558–2573.
   PubMed Web of Science ®Google Scholar
• Lu, L.; Qian, D.; Yang, J.; Jiang, S.; Guo, J.; Shang, E. X.; Duan, J. A. Identification of Isoquercitrin Metabolites Produced by Human Intestinal Bacteria Using UPLC-Q-TOF/MS. Biomed. Chromatogr. 2013, 27(4), 509–514.
   PubMed Web of Science ®Google Scholar
• Yang, X. N.; Wang, Y. J.; Liu, Y. S.; Tang, X. Pharmacokinetics of Salvianolic Acids After Intravenous Injection with and without Panax quinquefolium Protopanaxadiol Saponins in Rats. J. Ethnopharmacol. 2008, 117(3), 408–414.
   PubMed Web of Science ®Google Scholar
• Wu, X.; Liu, L.; Zhang, M.; Dan, W.; Wang, Y.; Sun, Y. Simultaneous Analysis of Isomers of Escin Saponins in Human Plasma by Liquid Chromatography–Tandem Mass Spectrometry: Application to a Pharmacokinetic Study After Oral Administration. J. Chromatogr. B. 2010, 878(11–12), 861–867.
   PubMed Web of Science ®Google Scholar
• Sousa, T.; Paterson, R.; Moore, V.; Carlsson, A.; Abrahamsson, B.; Basit, A. W. The Gastrointestinal Microbiota as a Site for the Biotransformation of Drugs. Int. J. Pharm. 2008, 363(1–2), 1–25.
   PubMed Web of Science ®Google Scholar
• Neu, J. Gastrointestinal Development and Meeting the Nutritional Needs of Premature Infants. Am. J. Clin. Nutr. 2008, 85(2), 629S–634S.
   Google Scholar
• Delzenne, N. M.; Cani, P. D. Interaction Between Obesity and the Gut Microbiota: Relevance in Nutrition. Annu. Rev. Nutr. 2011, 31(1), 15–31.
   PubMed Web of Science ®Google Scholar
• Siggers, R. H.; Siggers, J.; Thymann, T.; Boye, M.; Sangild, P. T. Nutritional Modulation of the Gut Microbiota and Immune System in Preterm Neonates Susceptible to Necrotizing Enterocolitis. J. Nutr. Biochem. 2011, 22(6), 511–521.
   PubMed Web of Science ®Google Scholar
• Prachi, G.; Premavalli, K. S. In-Vitro Studies on Functional Properties of Selected Natural Dietary Fibers. Int. J. Food Prop. 2011, 14(2), 397–410.
   Web of Science ®Google Scholar
• Zhu, Y.; Suits, M. D. L.; Thompson, A. J.; Chavan, S.; Dinev, Z.; Dumon, C. Mechanistic Insights into a Ca2+-Dependent Family of α-Mannosidases in a Human Gut Symbiont. Nat. Chem. Biol. 2010, 6(2), 125–132.
   PubMed Web of Science ®Google Scholar
• Hehemann, J. H.; Correc, G.; Barbeyron, T.; Helbert, W.; Czjzek, M.; Michel, G. Transfer of Carbohydrate-Active Enzymes from Marine Bacteria to Japanese Gut Microbiota. Nature 2010, 464(7290), 908–912.
   PubMed Web of Science ®Google Scholar