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Journal of Liquid Chromatography & Related Technologies Volume 41, 2018 - Issue 4
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Original Articles

Enantioseparation of (RS)-Bupropion and determination of configuration

Poonam MalikDepartment of Chemistry, Indian Institute of Technology Roorkee, Roorkee, IndiaView further author information
,
Anu DalalDepartment of Chemistry, Indian Institute of Technology Roorkee, Roorkee, IndiaView further author information
&
Ravi BhushanDepartment of Chemistry, Indian Institute of Technology Roorkee, Roorkee, IndiaCorrespondence[email protected]
View further author information
Pages 155-160 | Received 18 Dec 2017, Accepted 06 Jan 2018, Published online: 14 Feb 2018

References

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  • Bhatt, N. M.; Chavada, V. D.; Sanyal, M.; Shrivastav, P. S. Design of Experiment Assisted Concurrent Enantioseparation of Bupropion and Hydroxybupropion by High-Performance Thin-Layer Chromatography. Chirality 2017, 29, 80–88. DOI: 10.1002/chir.22673.
  • Batra, S.; Bhushan, R. Enantioresolution of (RS)-Bupropion by Reversed Phase High(Performance Liquid Chromatography using Cyanuric Chloride based Chiral Derivatizing Reagents having Amino Acids as Chiral Auxiliaries. J. Liq. Chrom. Rel. Technol. 2014, 37, 2515–2528. DOI: 10.1002/bmc.1653.
  • Bhushan, R.; Batra, S. High-Performance Liquid Chromatographic Enantioseparation of (RS)-Bupropion Using Isothiocyanate-Based Chiral Derivatizing Reagents. Biomed. Chromatogr. 2013, 27, 956–959. DOI: 10.1002/bmc.2885.
  • Batra, S.; Singh, M.; Bhushan, R. L-Amino Acids as Chiral Selectors for the Enantioseparation of (±)-Bupropion by Ligand Exchange Thin-Layer Chromatography Using Cu(II) Complex via Four Different Approaches. J. Planar Chromatogr. Mod. TLC 2014, 27, 367–371.
  • Singh, M.; Bhushan, R. HPLC Enantioseparation of Racemic Bupropion, Baclofen and Etodolac: Modification of Conventional Ligand Exchange Approach by Pre-Column Formation of ‘Chiral Ligand Exchange Complexes’. Biomed. Chromatogr. 2016, 30, 1728–1732.
  • Munro, J.; Gormley, J. P.; Walker, T. A. Bupropion Hydrochloride: The Development of a Chiral Separation using AGP Column. J. Liq. Chrom. Rel. Technol. 2001, 24, 327–339. DOI: 10.1081/jlc-100001337.
  • Munro, J.; Walker, T. A. Bupropion Hydrochloride: The Development of a Chiral Separation Using an Ovomucoid Column. J. Chromatogr. A 2001, 913, 275–282. DOI: 10.1016/s0021-9673(01)00639-2.
  • Ali, I.; Suhail, M.; Alothman, Z. A.; Alwarthan, A. Chiral Separation and Modeling of Baclofen, Bupropion, and Etodolac Profens on Amylose Reversed Phase Chiral Column. Chirality 2017, 29, 386–397. DOI: 10.1002/chir.22717.
  • Batra, S.; Bhushan, R. Resolution of Enantiomers of Bupropion and Its Metabolites by Liquid Chromatography. Biomed. Chromatogr. 2016, 30, 670–682. DOI: 10.1002/bmc.3572.
  • Sherma, J. Biennial Review of Planar Chromatography: 2011–2013. Cent. Eur. J. Chem. 2014, 12, 427–452. DOI: 10.2478/s11532-013-0402-5.
  • Kowalska, T.; Sherma, J. (Eds.). Thin Layer Chromatography in Chiral Separations and Analysis; CRC Press: Boca Raton, 2007.

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