125
Views
1
CrossRef citations to date
0
Altmetric
Research Articles

Extracting antioxidants from blueberries

, , &

References

  • Kalt, W.; Cassidy, A.; Howard, L. R.; Krikorian, R.; Stull, A. J.; Tremblay, F.; Zamora-Ros, R. Recent Research on the Health Benefits of Blueberries and Their Anthocyanins. Adv. Nutr. 2020, 11, 224–236. DOI: 10.1093/advances/nmz065.
  • Cassidy, A.; Mukamal, K. J.; Liu, L.; Franz, M.; Eliassen, A. H.; Rimm, E. B. High Anthocyanin Intake is Associated with a Reduced Risk of Myocardial Infarction in Young and Middle-Aged Women. Circulation. 2013, 127, 188–196. DOI: 10.1161/CIRCULATIONAHA.112.122408.
  • Wu, X.; Beecher, G. R.; Holden, J. M.; Haytowitz, D. B.; Gebhardt, S. E.; Prior, R. L. Concentrations of Anthocyanins in Common Foods in the United States and Estimation of Normal Consumption. J. Agric. Food Chem. 2006, 54, 4069–4075. DOI: 10.1021/jf060300l.
  • Mattioli, R.; Francioso, A.; Mosca, L.; Silva, P. Anthocyanins: A Comprehensive Review of Their Chemical Properties and Health Effects on Cardiovascular and Neurodegenerative Diseases. Molecules. 2020, 25, 3809. DOI: 10.3390/molecules25173809.
  • Cho, M. J.; Howard, L. R.; Prior, R. L.; Clark, J. R. Flavonoid Glycosides and Antioxidant Capacity of Various Blackberry, Blueberry and Red Grape Genotypes Determined by High-Performance Liquid Chromatography/Mass Spectrometry. J. Sci. Food Agric. 2004, 84, 1771–1782. DOI: 10.1002/jsfa.1885.
  • Shi, M.; Loftus, H.; McAinch, A. J.; Su, X. Q. Blueberry as a Source of Bioactive Compounds for the Treatment of Obesity, Type 2 Diabetes and Chronic Inflammation. J. Funct. Foods. 2017, 30, 16–29. DOI: 10.1016/j.jff.2016.12.036.
  • Jennings, A.; Welch, A. A.; Fairweather-Tait, S. J.; Kay, C.; Minihane, A.-M.; Chowienczyk, P.; Jiang, B.; Cecelja, M.; Spector, T.; Macgregor, A.; Cassidy, A. Higher Anthocyanin Intake is Associated with Lower Arterial Stiffness and Central Blood Pressure in Women. Am. J. Clin. Nutr. 2012, 96, 781–788. DOI: 10.3945/ajcn.112.042036.
  • Tran, P. H. L.; Tran, T. T. D. Blueberry Supplementation in Neuronal Health and Protective Technologies for Efficient Delivery of Blueberry Anthocyanins. Biomolecules. 2021, 11, 102. DOI: 10.3390/biom11010102.
  • Bell, L.; Williams, C. M. Blueberry Benefits to Cognitive Function across the Lifespan. Int. J. Food Sci. Nutr. 2021, 72, 650–652. DOI: 10.1080/09637486.2020.1852192.
  • Devore, E. E.; Kang, J. H.; Breteler, M. M. B.; Grodstein, F. Dietary Intakes of Berries and Flavonoids in Relation to Cognitive Decline. Ann. Neurol. 2012, 72, 135–143. DOI: 10.1002/ana.23594.
  • Vuong, Q. V.; Ngoc Thuy Pham, H.; Vu, H. T.; Dang, T. T.; Van Ngo, T.; Chalmers, A. C. Fruit Characteristics, Phytochemical and Antioxidant Properties of Blueberry Ash (Elaeocarpus Reticulatus). Heliyon. 2018, 4, e00834. DOI: 10.1016/j.heliyon.2018.e00834.
  • Piechowiak, T.; Skóra, B.; Grzelak-Błaszczyk, K.; Sójka, M. Extraction of Antioxidant Compounds from Blueberry Fruit Waste and Evaluation of Their in Vitro Biological Activity in Human Keratinocytes (HaCaT). Food Anal. Methods. 2021, 14, 2317–2327. DOI: 10.1007/s12161-021-02056-7.
  • Dróżdż, P.; Šėžienė, V.; Pyrzynska, K. Phytochemical Properties and Antioxidant Activities of Extracts from Wild Blueberries and Lingonberries. Plant Foods Hum. Nutr. 2017, 72, 360–364. DOI: 10.1007/s11130-017-0640-3.
  • Hidalgo, G.-I.; Almajano, M. P. Red Fruits: Extraction of Antioxidants, Phenolic Content, and Radical Scavenging Determination: A Review. Antioxidants. 2017, 6, 7. DOI: 10.3390/antiox6010007.
  • Kähkönen, M. P.; Hopia, A. I.; Heinonen, M. Berry Phenolics and Their Antioxidant Activity. J. Agric. Food Chem. 2001, 49, 4076–4082. DOI: 10.1021/jf010152t.
  • Galvan d’Alessandro, L.; Kriaa, K.; Nikov, I.; Dimitrov, K. Ultrasound Assisted Extraction of Polyphenols from Black Chokeberry. Sep. Purif. Technol. 2012, 93, 42–47. DOI: 10.1016/j.seppur.2012.03.024.
  • Galván D’Alessandro, L.; Dimitrov, K.; Vauchel, P.; Nikov, I. Kinetics of Ultrasound Assisted Extraction of Anthocyanins from Aronia Melanocarpa (Black Chokeberry) Wastes. Chem. Eng. Res. Des. 2014, 92, 1818–1826. DOI: 10.1016/j.cherd.2013.11.020.
  • Paes, J.; Dotta, R.; Barbero, G. F.; Martínez, J. Extraction of Phenolic Compounds and Anthocyanins from Blueberry (Vaccinium Myrtillus L.) Residues Using Supercritical CO2 and Pressurized Liquids. J. Supercrit. Fluids. 2014, 95, 8–16. DOI: 10.1016/j.supflu.2014.07.025.
  • Périno-Issartier, Sandrine, Abert-Vian, Maryline, Chemat, Farid, Zill-e-Huma,. Solvent Free Microwave-Assisted Extraction of Antioxidants from Sea Buckthorn (Hippophae Rhamnoides) Food by-Products. Food Bioprocess Technol. 2011, 4 (6), 1020–1028. DOI: 10.1007/s11947-010-0438-x.
  • Suktham, T.; Jones, A.; Soliven, A.; Dennis, G. R.; Shalliker, R. A. A Comparison of the Performance of the Cupric Reducing Antioxidant Potential Assay and the Ferric Reducing Antioxidant Power Assay for the Analysis of Antioxidants Using Reaction Flow Chromatography. Microchem. J. 2019, 149, 104046. DOI: 10.1016/j.microc.2019.104046.
  • Çelik, S. E.; Özyürek, M.; Güçlü, K.; Apak, R. Determination of Antioxidants by a Novel on-Line HPLC-Cupric Reducing Antioxidant Capacity (CUPRAC) Assay with Post-Column Detection. Anal. Chim. Acta. 2010, 674, 79–88. DOI: 10.1016/j.aca.2010.06.013.
  • Laroze, L. E.; Díaz-Reinoso, B.; Moure, A.; Zúñiga, M. E.; Domínguez, H. Extraction of Antioxidants from Several Berries Pressing Wastes Using Conventional and Supercritical Solvents. Eur. Food Res. Technol. 2010, 231, 669–677. DOI: 10.1007/s00217-010-1320-9.
  • Boeing, J. S.; Barizão, E. O. E.; Silva, B. C.; Montanher, P. F.; de Cinque Almeida, V.; Visentainer, J. V. Evaluation of Solvent Effect on the Extraction of Phenolic Compounds and Antioxidant Capacities from the Berries: Application of Principal Component Analysis. Chem. Cent. J. 2014, 8, 48. DOI: 10.1186/s13065-014-0048-1.
  • Li, X.; Zhu, F.; Zeng, Z. Effects of Different Extraction Methods on Antioxidant Properties of Blueberry Anthocyanins. Open Chem. 2021, 19, 138–148. DOI: 10.1515/chem-2020-0052.
  • Kähkönen, M. P.; Heinämäki, J.; Ollilainen, V.; Heinonen, M. Berry Anthocyanins: Isolation, Identification and Antioxidant Activities. J. Sci. Food Agric. 2003, 83, 1403–1411. DOI: 10.1002/jsfa.1511.
  • Castañeda-Ovando, A.; Pacheco-Hernández, M. d L.; Páez-Hernández, M. E.; Rodríguez, J. A.; Galán-Vidal, C. A. Chemical Studies of Anthocyanins: A Review. Food Chem. 2009, 113, 859–871. DOI: 10.1016/j.foodchem.2008.09.001.
  • Barnes, J. S.; Nguyen, H. P.; Shen, S.; Schug, K. A. General Method for Extraction of Blueberry Anthocyanins and Identification Using High Performance Liquid Chromatography–Electrospray Ionization-Ion Trap-Time of Flight-Mass Spectrometry. J. Chromatogr. A. 2009, 1216, 4728–4735. DOI: 10.1016/j.chroma.2009.04.032.
  • Jones, A.; Pravadali-Cekic, S.; Hua, S.; Kocic, D.; Camenzuli, M.; Dennis, G.; Shalliker, A. Post Column Derivatization Using Reaction Flow High Performance Liquid Chromatography Columns. J. Visual. Exp. 2016, 62. DOI: 10.3791/53462.
  • Suktham, T.; Soliven, A.; Jones, A.; Dennis, G.; Shalliker, R. Information Rich Chromatographic Separations of Natural Samples: The Analysis of Antioxidants in Coffee Using Post Column Derivatisation and the CUPRAC Assay on Narrow Bore Reaction Flow HPLC Columns. Microchem. J. 2020, 153, 104403. DOI: 10.1016/j.microc.2019.104403.
  • Manwaring, C. W.; Cravino, J. A.; Patel, M.; Stathakis, J. G. H.; Soliven, A.; Suktham, T.; Shalliker, R. A. Using HPLC with in-Column Derivatization to Authenticate Coffee Samples. Molecules. 2023, 28, 1651. DOI: 10.3390/molecules28041651.
  • Stathakis, J. G. H.; Cravino, J. A.; Shalliker, R. A. Antioxidants in Coffee: An Exercise Using HPLC with Post-Column Derivatization and Statistical Analysis. J. Chem. Educ. 2023, 100, 1564–1570. DOI: 10.1021/acs.jchemed.1c01191.
  • Apak, R.; Güçlü, K.; Özyürek, M.; Çelik, S. E. Mechanism of Antioxidant Capacity Assays and the CUPRAC (Cupric Ion Reducing Antioxidant Capacity) Assay. Microchim. Acta. 2008, 160, 413–419. DOI: 10.1007/s00604-007-0777-0.
  • Bai, X.; Zhou, L.; Zhou, L.; Cang, S.; Liu, Y.; Liu, R.; Liu, J.; Feng, X.; Fan, R. The Research Progress of Extraction, Purification and Analysis Methods of Phenolic Compounds from Blueberry: A Comprehensive Review. Molecules. 2023, 28, 3610. DOI: 10.3390/molecules28083610.
  • Robards, K.; Antolovich, M. Analytical Chemistry of Fruit BioflavonoidsA Review. Analyst. 1997, 122, 11R–34R. DOI: 10.1039/a606499j.
  • Revilla, E.; Ryan, J.-M.; Martín-Ortega, G. Comparison of Several Procedures Used for the Extraction of Anthocyanins from Red Grapes. J. Agric. Food Chem. 1998, 46, 4592–4597. DOI: 10.1021/jf9804692.
  • Flavonoids: Chemistry, Biochemistry and Applications; Andersen, O. M., Markham, K. R., Eds.; CRC Press: Boca Raton, 2005. DOI: 10.1201/9781420039443.
  • Liazid, A.; Palma, M.; Brigui, J.; Barroso, C. G. Investigation on Phenolic Compounds Stability during Microwave-Assisted Extraction. J. Chromatogr. A. 2007, 1140, 29–34. DOI: 10.1016/j.chroma.2006.11.040.
  • Snyder, L. R.; Kirkland, J. J. Introduction to Modern Liquid Chromatography, 2nd ed.; John Wiley & Sons: Hoboken, 1979.
  • Clark, R. Substances Generally Recognized as Safe (GRAS) Contents. 2015. https://policycommons.net/artifacts/2128638/substances-generally-recognized-as-safe-gras-contents/2883936/ (accessed Jul 15, 2023).
  • Molino, A.; Rimauro, J.; Casella, P.; Cerbone, A.; Larocca, V.; Chianese, S.; Karatza, D.; Mehariya, S.; Ferraro, A.; Hristoforou, E.; Musmarra, D. Extraction of Astaxanthin from Microalga Haematococcus Pluvialis in Red Phase by Using Generally Recognized as Safe Solvents and Accelerated Extraction. J. Biotechnol. 2018, 283, 51–61. DOI: 10.1016/j.jbiotec.2018.07.010.
  • Rodríguez, L. C.; Campa[nbreve]Ta, A. M. G.; Linares, C. J.; Ceba, M. R. Estimation of Performance Characteristics of an Analytical Method Using the Data Set of the Calibration Experiment. Anal. Lett. 1993, 26, 1243–1258. DOI: 10.1080/00032719308019900.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.