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Original Articles

What Do You Know About Maryjane? A Systematic Review of the Current Data on the THC:CBD Ratio

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References

  • Aran, A., Cassuto, H., Lubotzky, A., Wattad, N., & Hazan, E. (2019). Brief report: Cannabidiol-rich cannabis in children with autism spectrum disorder and severe behavioral problems—A retrospective feasibility study. Journal of Autism and Developmental Disorders, 49(3), 1284–1288. doi:10.1007/s10803-018-3808-2
  • Barchel, D., Stolar, O., De-Haan, T., Ziv-Baran, T., Saban, N., Fuchs, D. O., … Berkovitch, M. (2019). Oral cannabidiol use in children with autism spectrum disorder to treat related symptoms and co-morbidities. Frontiers in Pharmacology, 9, 1521. doi:10.3389/fphar.2018.01521
  • Bidwell, L. C., Mueller, R., Yorkwilliams, S. L., Hagerty, S., Bryan, A. D., & Hutchison, K. E. (2018). A novel observational method for assessing acute responses to cannabis: Preliminary validation using legal market strains. Cannabis and Cannabinoid Research, 3(1), 35–44. doi:10.1089/can.2017.0038
  • Ciccone, C. D. (2017). Medical marijuana: Just the beginning of a long, strange trip? Physical Therapy, 97(2), 239–248. doi:10.2522/ptj.20160367
  • Grof, C. P. L. (2018). Cannabis, from plant to pill. British Journal of Clinical Pharmacology, 84(11), 2463–2467. doi:10.1111/bcp.13618
  • Libzon, S., Schleider, L. B.-L., Saban, N., Levit, L., Tamari, Y., Linder, I., … Blumkin, L. (2018). Medical cannabis for pediatric moderate to severe complex motor disorders. Journal of Child Neurology, 33(9), 565–571. doi:10.1177/0883073818773028
  • McCoy, B., Wang, L., Zak, M., Al‐Mehmadi, S., Kabir, N., Alhadid, K., … Snead, O. C. 3rd. (2018). A prospective open-label trial of a CBD/THC cannabis oil in Dravet syndrome. Annals of Clinical and Translational Neurology, 5(9), 1077–1088. doi:10.1002/acn3.621
  • Morgan, C. J. A., Freeman, T. P., Hindocha, C., Schafer, G., Gardner, C., & Curran, H. V. (2018). Individual and combined effects of acute delta-9-tetrahydrocannabinol and cannabidiol on psychotomimetic symptoms and memory function. Translational Psychiatry, 8(1), 181. doi:10.1038/s41398-018-0191-x
  • Morgan, C. J., Freeman, T. P., Schafer, G. L., & Curran, H. V. (2010). Cannabidiol attenuates the appetitive effects of delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis. Neuropsychopharmacology, 35(9), 1879–1885. doi:10.1038/npp.2010.58
  • Pacifici, R., Marchei, E., Salvatore, F., Guandalini, L., Busardò, F. P., & Pichini, S. (2017). Evaluation of cannabinoids concentration and stability in standardized preparations of cannabis tea and cannabis oil by ultra-high performance liquid chromatography tandem mass spectrometry. Clinical Chemistry and Laboratory Medicine, 55(10), 1555–1563. doi:10.1515/cclm-2016-1060
  • Pacifici, R., Pichini, S., Pellegrini, M., Rotolo, M. C., Giorgetti, R., Tagliabracci, A., … Huestis, M. A. (2019). THC and CBD concentrations in blood, oral fluid and urine following a single and repeated administration of “light cannabis”. Clinical Chemistry and Laboratory Medicine. doi:10.1515/cclm-2019-0119
  • Pacifici, R., Pichini, S., Pellegrini, M., Tittarelli, R., Pantano, F., Mannocchi, G., … Busardò, F. P. (2018). Determination of cannabinoids in oral fluid and urine of “light cannabis” consumers: A pilot study. Clinical Chemistry and Laboratory Medicine, 57(2), 238–243. doi:10.1515/cclm-2018-0566
  • Pichini, S., Mannocchi, G., Berretta, P., Zaami, S., Pirani, F., Pacifici, R., & Busardo, F. P. (2020). Delta9-tetrahydrocannabinol and cannabidiol time courses in the sera of “light cannabis” smokers: Discriminating light cannabis use from illegal and medical cannabis use. Therapeutic Drug Monitoring, 42(1), 151–156. doi:10.1097/FTD.0000000000000683
  • Russo, E. B. (2016). Current therapeutic cannabis controversies and clinical trial design issues. Frontiers in Pharmacology, 7, 309. doi:10.3389/fphar.2016.00309
  • Russo, E., & Guy, G. W. (2006). A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. Medical Hypotheses, 66(2), 234–246. doi:10.1016/j.mehy.2005.08.026
  • Russo, E. B., Mead, A. P., & Sulak, D. (2015). Current status and future of cannabis research. Clinical Researcher, 29(2), 58–63.
  • Saccà, F., Pane, C., Carotenuto, A., Massarelli, M., Lanzillo, R., Florio, E. B., & Brescia Morra, V. (2016). The use of medical-grade cannabis (bedrocan®) in patients non-responders to nabiximols (sativex®). Multiple Sclerosis, 22, 686. doi:10.1177/1352458516663086
  • Solowij, N., Broyd, S., Greenwood, L-M., van Hell, H., Martelozzo, D., Rueb, K., … Croft, R. (2019). A randomised controlled trial of vaporised δ9-tetrahydrocannabinol and cannabidiol alone and in combination in frequent and infrequent cannabis users: Acute intoxication effects. European Archives of Psychiatry and Clinical Neuroscience, 269(1), 17–35. doi:10.1007/s00406-019-00978-2
  • Tzadok, M., Uliel-Siboni, S., Linder, I., Kramer, U., Epstein, O., Menascu, S., … Ben-Zeev, B. (2016). CBD-enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience. Seizure, 35, 41–44. doi:10.1016/j.seizure.2016.01.004
  • van de Donk, T., Niesters, M., Kowal, M. A., Olofsen, E., Dahan, A., & van Velzen, M. (2019). An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia. Pain, 160(4), 860–869. doi:10.1097/j.pain.0000000000001464

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