Substance Use and Healthcare Utilization Across the Pre-Exposure Prophylaxis (PrEP) Care Cascade among Black and Latino Men Who Have Sex with Men

References

• Anderson, P. L., Glidden, D. V., Liu, A., Buchbinder, S., Lama, J. R., Guanira, J. V., McMahan, V., Bushman, L. R., Casapía, M., Montoya-Herrera, O., & Veloso, V. G. (2012). Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men. Science Translational Medicine, 4(151), 125–151.
   Google Scholar
• Behrens, J. T. (1997). Principles and procedures of exploratory data analysis. Psychological Methods, 2(2), 131–160. https://doi.org/10.1037/1082-989X.2.2.131
   Web of Science ®Google Scholar
• Blashill, A. J., Brady, J. P., Rooney, B. M., Rodriguez-Diaz, C. E., Horvath, K. J., Blumenthal, J., Morris, S., Moore, D. J., & Safren, S. A. (2020). Syndemics and the PrEP Cascade: Results from a sample of young latino men who have sex with men. Archives of Sexual Behavior, 49(1), 125–135. https://doi.org/10.1007/s10508-019-01470-7
   PubMed Web of Science ®Google Scholar
• Buchbinder, S. P. (2018). Maximizing the benefits of HIV preexposure prophylaxis. Topics in Antiviral Medicine, 25(4), 138–142.
   PubMedGoogle Scholar
• Cahill, S., Taylor, S. W., Elsesser, S. A., Mena, L., Hickson, D., & Mayer, K. H. (2017). Stigma, medical mistrust, and perceived racism may affect PrEP awareness and uptake in black compared to white gay and bisexual men in Jackson, Mississippi and Boston, Massachusetts. AIDS Care, 29(11), 1351–1358. https://doi.org/10.1080/09540121.2017.1300633
   PubMed Web of Science ®Google Scholar
• Calabrese, S. K., Earnshaw, V. A., Krakower, D. S., Underhill, K., Vincent, W., Magnus, M., Hansen, N. B., Kershaw, T. S., Mayer, K. H., Betancourt, J. R., & Dovidio, J. F. (2018). A closer look at racism and heterosexism in medical students’ clinical decision-making related to HIV pre-exposure prophylaxis (PrEP): Implications for PrEP education. AIDS and Behavior, 22(4), 1122–1138. 10.1007/s10461-017-1979-z
   PubMed Web of Science ®Google Scholar
• Card, K. G., Fournier, A. B., Sorge, J. T., Morgan, J., Grace, D., Ham, D., Lachowsky, N. J., & Trussler, T. (2020). Substance use patterns and awareness of biomedical HIV prevention strategies among sexual and gender minority men in Canada. AIDS Care, 32(12), 1506–1514. https://doi.org/10.1080/09540121.2020.1719026
   PubMed Web of Science ®Google Scholar
• Collins, L. M., Schafer, J. L., & Kam, C. M. (2001). A comparison of inclusive and restrictive strategies in modern missing data procedures. Psychological Methods, 6(4), 330–351.
   PubMed Web of Science ®Google Scholar
• Dietz, E., Clum, G. A., Chung, S. E., Leonard, L., Murphy, D. A., Perez, L. V., Harper, G. W., & Ellen, J. M. (2010). Adherence to scheduled appointments among HIV-infected female youth in five U.S. cities. The Journal of Adolescent Health: official Publication of the Society for Adolescent Medicine, 46(3), 278–283. https://doi.org/10.1016/j.jadohealth.2009.06.013
   PubMedGoogle Scholar
• Eaton, L. A., Kalichman, S. C., Price, D., Finneran, S., Allen, A., & Maksut, J. (2017). Stigma and conspiracy beliefs related to pre-exposure prophylaxis (PrEP) and interest in using PrEP among black and white men and transgender women who have sex with men. AIDS and Behavior, 21(5), 1236–1246. https://doi.org/10.1007/s10461-017-1690-0
   PubMed Web of Science ®Google Scholar
• García, M., & Harris, A. L. (2017). PrEP awareness and decision-making for Latino MSM in San Antonio, Texas. PloS One, 12(9), e0184014. https://doi.org/10.1371/journal.pone.0184014
   PubMed Web of Science ®Google Scholar
• Garnett, M., Hirsch-Moverman, Y., Franks, J., Hayes-Larson, E., El-Sadr, W. M., & Mannheimer, S. (2018). Limited awareness of pre-exposure prophylaxis among black men who have sex with men and transgender women in New York City. AIDS Care, 30(1), 9–17. https://doi.org/10.1080/09540121.2017.1363364
   PubMed Web of Science ®Google Scholar
• Goodman-Meza, D., Beymer, M. R., Kofron, R. M., Amico, K. R., Psaros, C., Bushman, L. R., Anderson, P. L., Bolan, R., Jordan, W. C., Rooney, J. F., Wohl, A. R., & Landovitz, R. J. (2019). Effective use of pre-exposure prophylaxis (PrEP) among stimulant users with multiple condomless sex partners: A longitudinal study of men who have sex with men in Los Angeles. AIDS Care, 31(10), 1228–1233. https://doi.org/10.1080/09540121.2019.1595523
   PubMed Web of Science ®Google Scholar
• Graham, J. W., Olchowski, A. E., & Gilreath, T. D. (2007). How many imputations are really needed? Some practical clarifications of multiple imputation theory. Prevention Science, 8(3), 206–213. https://doi.org/10.1007/s11121-007-0070-9
   PubMed Web of Science ®Google Scholar
• Grant, R. M., Anderson, P. L., McMahan, V., Liu, A., Amico, K. R., Mehrotra, M., Hosek, S., Mosquera, C., Casapia, M., Montoya, O., Buchbinder, S., Veloso, V. G., Mayer, K., Chariyalertsak, S., Bekker, L.-G., Kallas, E. G., Schechter, M., Guanira, J., Bushman, L., … Glidden, D. V. (2014). Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: A cohort study. The Lancet Infectious Diseases, 14(9), 820–829. https://doi.org/10.1016/S1473-3099(14)70847-3
   PubMed Web of Science ®Google Scholar
• Grant, R. M., Lama, J. R., Anderson, P. L., McMahan, V., Liu, A. Y., Vargas, L., Goicochea, P., Casapía, M., Guanira-Carranza, J. V., Ramirez-Cardich, M. E., Montoya-Herrera, O., Fernández, T., Veloso, V. G., Buchbinder, S. P., Chariyalertsak, S., Schechter, M., Bekker, L.-G., Mayer, K. H., Kallás, E. G.,… Glidden, D. V. (2010). Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. New England Journal of Medicine, 363(27), 2587–2599. https://doi.org/10.1056/NEJMoa1011205
   PubMed Web of Science ®Google Scholar
• Grov, C., Rendina, H. J., John, S. A., & Parsons, J. T. (2019). Determining the roles that club drugs, marijuana, and heavy drinking play in PrEP medication adherence among gay and bisexual men: Implications for treatment and research. AIDS and Behavior, 23(5), 1277–1286. https://doi.org/10.1007/s10461-018-2309-9
   PubMed Web of Science ®Google Scholar
• Hair, J. F., Black, W. C., Babin, B. J., & Anderson, R. E. (2010). Multivariate data analysis (7th ed.). Prentice-Hall, Inc.
   Google Scholar
• Higgins-Biddle, J. C., & Babor, T. F. (2018). A review of the Alcohol Use Disorders Identification Test (AUDIT), AUDIT-C, and USAUDIT for screening in the United States: Past issues and future directions. The American Journal of Drug and Alcohol Abuse, 44(6), 578–586. https://doi.org/10.1080/00952990.2018.1456545
   PubMed Web of Science ®Google Scholar
• Hoenigl, M., Jain, S., Moore, D., Collins, D., Sun, X., Anderson, P. L., Corado, K., Blumenthal, J. S., Daar, E. S., Milam, J., Dubé, M. P., & Morris, S. (2018). Substance use and adherence to HIV preexposure prophylaxis for men who have sex with men. Emerging Infectious Diseases, 24(12) https://doi.org/10.3201/eid2412.180400
   Web of Science ®Google Scholar
• Hojilla, J. C., Satre, D. D., Glidden, D. V., McMahan, V. M., Gandhi, M., Defechereux, P., Guanira, J. V., Mehrotra, M., Grant, R. M., & Carrico, A. W. (2019). Brief report: Cocaine use and pre-exposure prophylaxis: Adherence, care engagement, and kidney function. Journal of Acquired Immune Deficiency Syndromes (1999), 81(1), 78–82. https://doi.org/10.1097/QAI.0000000000001972
   PubMed Web of Science ®Google Scholar
• Hojilla, J. C., Vlahov, D., Glidden, D. V., Amico, K. R., Mehrotra, M., Hance, R., Grant, R. M., & Carrico, A. W. (2018). Skating on thin ice: Stimulant use and sub-optimal adherence to HIV pre-exposure prophylaxis. Journal of the International AIDS Society, 21(3), 1–5. https://doi.org/10.1002/jia2.25103
   Google Scholar
• Honaker, J., King, G., & Blackwell, M. (2011). Amelia II: A program for missing data. Journal of Statistical Software, 45(7), 1–47. [Database] https://doi.org/10.18637/jss.v045.i07
   Web of Science ®Google Scholar
• Hoots, B. E., Finlayson, T., Nerlander, L., & Paz-Bailey, G. (2016). Willingness to take, use of, and indications for pre-exposure prophylaxis among men who have sex with men—20 US cities, 2014. Clinical Infectious Diseases 63(5), 672–677. https://doi.org/10.1093/cid/ciw367
   PubMed Web of Science ®Google Scholar
• Kalichman, S. C., & Eaton, L. (2017). Alcohol‐antiretroviral interactive toxicity beliefs as a potential barrier to HIV pre‐exposure prophylaxis among men who have sex with men. Journal of the International AIDS Society, 20(1), 21534. https://doi.org/10.7448/IAS.20.1.21534
   PubMedGoogle Scholar
• Kanny, D., Jeffries, W. L., Chapin-Bardales, J., Denning, P., Cha, S., Finlayson, T., Wejnert, C., Abrego, M., Al-Tayyib, A., Anderson, B., Barak, N., Beckford, J. M., Bolden, B., Brady, K. A., Brandt, M. G., Brantley, M., Braunstein, S., Buyu, C., Cano, R., … Wortley, P. (2019). Racial/ethnic disparities in HIV preexposure prophylaxis among men who have sex with men — 23 urban areas, 2017. MMWR. Morbidity and Mortality Weekly Report, 68(37), 801–806. http://dx.doi.org/10.15585/mmwr.mm6837a2
   PubMed Web of Science ®Google Scholar
• Kimball, D., Rivera, D., Gonzales, M., & Blashill, A. J. (2020). Medical mistrust and the PrEP cascade among Latino sexual minority men. AIDS and Behavior, 24(12), 3456–3461. https://doi.org/10.1007/s10461-020-02916-z
   PubMed Web of Science ®Google Scholar
• Laborde, N. D., Kinley, P. M., Spinelli, M., Vittinghoff, E., Whitacre, R., Scott, H. M., & Buchbinder, S. P. (2020). Understanding PrEP persistence: Provider and patient perspectives. AIDS and Behavior, 24(9), 2509–2519. https://doi.org/10.1007/s10461-020-02807-3
   PubMedGoogle Scholar
• Lancki, N., Almirol, E., Alon, L., McNulty, M., & Schneider, J. A. (2018). Preexposure prophylaxis guidelines have low sensitivity for identifying seroconverters in a sample of young Black MSM in Chicago. AIDS (London, England), 32(3), 383–392. https://doi.org/10.1097/qad.0000000000001710
   PubMedGoogle Scholar
• Leech, A. A., Christiansen, C. L., Linas, B. P., Jacobsen, D. M., Morin, I., & Drainoni, M. L. (2020). Healthcare practitioner experiences and willingness to prescribe pre-exposure prophylaxis in the US. Plos One, 15(9), e0238375. https://doi.org/10.1371/journal.pone.0238375
   PubMedGoogle Scholar
• Lelutiu-Weinberger, C., & Golub, S. A. (2016). Enhancing PrEP access for black and Latino men who have sex with men. JAIDS Journal of Acquired Immune Deficiency Syndromes, 73(5), 547–555. https://doi.org/10.1097/QAI.0000000000001140
   PubMed Web of Science ®Google Scholar
• Little, T. D., Jorgensen, T. D., Lang, K. M., & Moore, E. W. G. (2014). On the joys of missing data. Journal of Pediatric Psychology, 39(2), 151–162. https://doi.org/10.1093/jpepsy/jst048
   PubMed Web of Science ®Google Scholar
• Morgan, E., Dyar, C., Hayford, C. S., Whitton, S. W., Newcomb, M. E., & Mustanski, B. (2021). Perceptions of marijuana decriminalization among young sexual and gender minorities in Chicago: An initial measure validation and test of longitudinal associations with use. Cannabis and Cannabinoid Research, 6(2), 156–164. https://doi.org/10.1089/can.2019.0072
   PubMedGoogle Scholar
• Morgan, E., Khanna, A. S., Skaathun, B., Michaels, S., Young, L., Duvoisin, R., Chang, M., Voisin, D., Cornwell, B., Coombs, R. W., Friedman, S. R., & Schneider, J. A. (2016). Marijuana use among young black men who have sex with men and the HIV care continuum: Findings from the uConnect cohort. Substance Use & Misuse, 51(13), 1751–1759. https://doi.org/10.1080/10826084.2016.1197265
   PubMed Web of Science ®Google Scholar
• Morgan, E., Moran, K., Ryan, D. T., Mustanski, B., & Newcomb, M. E. (2018). Threefold increase in PrEP uptake over time with high adherence among young men who have sex with men in Chicago. AIDS and Behavior, 22(11), 3637–3644. https://doi.org/10.1007/s10461-018-2122-5
   PubMedGoogle Scholar
• Morgan, E., Ryan, D. T., Newcomb, M. E., & Mustanski, B. (2018). High rate of discontinuation may diminish PrEP coverage among young men who have sex with men. AIDS and Behavior, 22(11), 3645–3648. https://doi.org/10.1007/s10461-018-2125-2
   PubMed Web of Science ®Google Scholar
• Muthén, L. K., & Muthén, B. O. (1998–2011). Mplus user’s guide (6th ed.). Muthén & Muthén.
   Google Scholar
• Nunn, A. S., Brinkley-Rubinstein, L., Oldenburg, C. E., Mayer, K. H., Mimiaga, M., Patel, R., & Chan, P. A. (2017). Defining the HIV pre-exposure prophylaxis care continuum. AIDS (London, England), 31(5), 731–734. https://doi.org/10.1097/qad.0000000000001385
   PubMed Web of Science ®Google Scholar
• Okafor, C. N., Hucks-Ortiz, C., Hightow-Weidman, L. B., Magnus, M., Emel, L., Beauchamp, G., Kuo, I., Hendrix, C., Mayer, K. H., & Shoptaw, S. J. (2020). Brief report: Associations between self-reported substance use behaviors and PrEP acceptance and adherence among black MSM in the HPTN 073 study. JAIDS Journal of Acquired Immune Deficiency Syndromes, 85(1), 23–29. https://doi.org/10.1097/QAI.0000000000002407
   PubMed Web of Science ®Google Scholar
• Oldfield, B. J., & Edelman, E. J. (2021). Addressing unhealthy alcohol use and the HIV pre-exposure prophylaxis care continuum in primary care: a scoping review. AIDS and Behavior, 25(6), 1777–1789. https://doi.org/10.1007/s10461-020-03107-6
   PubMedGoogle Scholar
• Oostrom, L., Rosentel, K., Motley, D., & Hill, B. J. (2020). Discordance in objective and self-perceived HIV risk: A potential barrier to pre-exposure prophylaxis in young gay and bisexual men. The Journal of the Association of Nurses in AIDS Care, 31(1), 103–109. https://doi.org/10.1097/jnc.0000000000000137
   PubMedGoogle Scholar
• Parmley, L. E., Harris, T. G., Chingombe, I., Mapingure, M., Mugurungi, O., Rogers, J. H., Gozhora, P., Wu, Y., Samba, C., Musuka, G., & Hakim, A. J. (2022). Engagement in the pre‐exposure prophylaxis (PrEP) cascade among a respondent‐driven sample of sexually active men who have sex with men and transgender women during early PrEP implementation in Zimbabwe. Journal of the International AIDS Society, 25(2), e25873. https://doi.org/10.1002/jia2.25873
   PubMedGoogle Scholar
• Parsons, J. T., Kutnick, A. H., Halkitis, P. N., Punzalan, J. C., & Carbonari, J. P. (2005). Sexual risk behaviors and substance use among alcohol abusing HIV-positive men who have sex with men. Journal of Psychoactive Drugs, 37(1), 27–36. https://doi.org/10.1080/02791072.2005.10399746
   PubMed Web of Science ®Google Scholar
• Parsons, J. T., Rendina, H. J., Lassiter, J. M., Whitfield, T. H., Starks, T. J., & Grov, C. (2017). Uptake of HIV pre-exposure prophylaxis (PrEP) in a national cohort of gay and bisexual men in the United States: the motivational PrEP cascade. Journal of Acquired Immune Deficiency Syndromes (1999), 74(3), 285–292. https://doi.org/10.1097/QAI.0000000000001251.
   PubMed Web of Science ®Google Scholar
• Quinn, K., Dickson-Gomez, J., Zarwell, M., Pearson, B., & Lewis, M. (2019). A gay man and a doctor are just like, a recipe for destruction”: How racism and homonegativity in healthcare settings influence PrEP uptake among young black MSM. AIDS and Behavior, 23(7), 1951–1963. https://doi.org/10.1007/s10461-018-2375-z
   PubMed Web of Science ®Google Scholar
• Ross, P. T., Hart-Johnson, T., Santen, S. A., & Zaidi, N. L. B. (2020). Considerations for using race and ethnicity as quantitative variables in medical education research. Perspectives on Medical Education, 9(5), 318–323. https://doi.org/10.1007/s40037-020-00602-3
   PubMed Web of Science ®Google Scholar
• Rubin, D. B. (1987). Multiple imputation for nonresponse in surveys. Wiley.
   Google Scholar
• Schafer, J. L., & Graham, J. W. (2002). Missing data: Our view of the state of the art. Psychological Methods, 7(2), 147–177.
   PubMed Web of Science ®Google Scholar
• Scott, H. M., Spinelli, M., Vittinghoff, E., Morehead-Gee, A., Hirozawa, A., James, C., Hammer, H., Liu, A., Gandhi, M., & Buchbinder, S. (2019). Racial/ethnic and HIV risk category disparities in preexposure prophylaxis discontinuation among patients in publicly funded primary care clinics. AIDS, 33(14), 2189–2195. https://doi.org/10.1097/QAD.0000000000002347
   PubMed Web of Science ®Google Scholar
• Shuper, P. A., Joharchi, N., Bogoch, I. I., Loutfy, M., Crouzat, F., El-Helou, P., Knox, D. C., Woodward, K., & Rehm, J. (2020). Alcohol consumption, substance use, and depression in relation to HIV pre-exposure prophylaxis (PrEP) nonadherence among gay, bisexual, and other men-who-have-sex-with-men. BMC Public Health, 20(1), 1782. https://doi.org/10.1186/s12889-020-09883-z
   Google Scholar
• Silapaswan, A., Krakower, D., & Mayer, K. H. (2017). Pre-exposure prophylaxis: A narrative review of provider behavior and interventions to increase PrEP implementation in primary care. Journal of General Internal Medicine, 32(2), 192–198. https://doi.org/10.1007/s11606-016-3899-4
   PubMed Web of Science ®Google Scholar
• Spector, A. Y., Remien, R. H., & Tross, S. (2015). PrEP in substance abuse treatment: A qualitative study of treatment provider perspectives. Substance Abuse Treatment, Prevention, and Policy, 10, 1. 10.1186/1747-597X-10-1[PMC][25575428]
   PubMed Web of Science ®Google Scholar
• Storholm, E. D., Volk, J. E., Marcus, J. L., Silverberg, M. J., & Satre, D. D. (2017). Risk perception, sexual behaviors, and PrEP adherence among substance-using men who have sex with men: A qualitative study. Prevention Science, 18(6), 737–747. https://doi.org/10.1007/s11121-017-0799-8
   PubMed Web of Science ®Google Scholar
• Tangmunkongvorakul, A., Chariyalertsak, S., Amico, K. R., Saokhieo, P., Wannalak, V., Sangangamsakun, T., Goicochea, P., & Grant, R. (2013). Facilitators and barriers to medication adherence in an HIV prevention study among men who have sex with men in the iPrEx study in Chiang Mai, Thailand. AIDS Care, 25(8), 961–967. https://doi.org/10.1080/09540121.2012.748871
   PubMed Web of Science ®Google Scholar
• Willie, T. C., Kershaw, T. S., Blackstock, O., Galvao, R. W., Safon, C. B., Tekeste, M., Ogburn, D. F., Wilbourn, B., Modrakovic, D., Taggart, T., Kaplan, C., Caldwell, A., & Calabrese, S. K. (2021). Racial and ethnic differences in women’s HIV risk and attitudes towards pre-exposure prophylaxis (PrEP) in the context of the substance use, violence, and depression syndemic. AIDS Care, 33(2), 219–228. https://doi.org/10.1080/09540121.2020.1762067
   PubMed Web of Science ®Google Scholar