References
- Lalla RV, Bowen J, Barasch A, et al. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer 2014;120:1453–1461.
- Hong JH, Omur-Ozbek P, Stanek BT, et al. Taste and odor abnormalities in cancer patients. J Support Oncol 2009;7:58–65.
- Bensinger W, Schubert M, Ang KK, et al. NCCN task force report. prevention and management of mucositis in cancer care. J Natl Compr Canc Netw 2008;6:S1–S21. quiz S22-4.
- Cawley MM, Benson LM. Current trends in managing oral mucositis. Clin J Oncol Nurs 2005;9:584–592.
- Peterson DE, Bensadoun RJ, Roila F, et al. Management of oral and gastrointestinal mucositis: ESMO clinical practice guidelines. Ann Oncol 2011;22:vi78–vi84.
- Parkhill AL. Oral mucositis and stomatitis associated with conventional and targeted anticancer therapy. J Pharmacovigilance 2013;1:112.
- Lalla RV, Peterson DE. Treatment of mucositis, including new medications. Cancer J 2006;12:348–354.
- Hosseinjani H, Hadjibabaie M, Gholami K, et al. The efficacy of erythropoietin mouthwash in prevention of oral mucositis in patients undergoing autologous hematopoietic SCT: a double‐blind, randomized, placebo‐controlled trial. Hematol Oncol 2015; doi: 10.1002/hon.2250. [Epub ahead of print].
- McGuire DB, Fulton JS, Park J, et al. Systematic review of basic oral care for the management of oral mucositis in cancer patients. Support Care Cancer 2013;21:3165–3177.
- Mogensen S, Treldal C, Feldager E, et al. New lidocaine lozenge as topical anesthesia compared to lidocaine viscous oral solution before upper gastrointestinal endoscopy. Local Reg Anesth 2012;5:17–22.
- Alison Brayfield, ed. Martindale: the complete drug reference. 38th ed. London: Pharmaceutical Press; 2014. ISBN 978-0-85711-139-5.
- Köstler WJ, Hejna M, Wenzel C, Zielinski CC. Oral mucositis complicating chemotherapy and/or radiotherapy: options for prevention and treatment. CA Cancer J Clin 2001;51:290–315.
- Gøtzsche PC, Johansen HK. Nystatin prophylaxis and treatment in severely immunodepressed patients. Cochrane Database Syst Rev 2002;4:CD002033.
- Nicolatou-Galitis O, Dardoufas K, Markoulatos P, et al. Oral pseudomembranous candidiasis, herpes simplex virus-1 infection, and oral mucositis in head and neck cancer patients receiving radiotherapy and granulocyte-macrophage colony-stimulating factor (GM-CSF) mouthwash. J Oral Pathol Med 2001;30:471–480.
- Codd JE, Deasy P. Formulation development and in vivo evaluation of a novel bioadhesive lozenge containing a synergistic combination of antifungal agents. Int J Pharm 1998;173:13–24.
- Akpan A, Morgan R. Oral candidiasis. Postgrad Med J 2002;78:455–459.
- Wiseman M. The treatment of oral problems in the palliative patient. J Can Dent Assoc 2006;72:453–456.
- Thompson PJ, Wingfield HJ, Cosgrove RF, et al. Assessment of oral candidiasis in patients with respiratory disease and efficacy of a new nystatin formulation. Br Med J (Clin Res Ed) 1986;292:1699–1700.
- Ridgway F, Ward MD. Antifungal pastille formulation and method. USPatent 4,725,440.
- Sklenár Z, Scigel V, Horácková K, Slanar O. Compounded preparations with nystatin for oral and oromucosal administration. Acta Pol Pharm 2012;70:759–762.
- Chan CK, Fok KL, Poon CM. Flavored anesthetic lozenge versus xylocaine spray used as topical pharyngeal anesthesia for unsedated esophagogastroduodenoscopy: a randomized placebo-controlled trial. Surg Endosc 2010;24:897–901.
- Aps JKM, Martens LC. Review: the physiology of saliva and transfer of drugs into saliva. Forensic Sci Int 2005;150:119–131.
- Allen L. Troches and lozenges. Secundum artem. Current and Practical Compounding Information for the Pharmacist 2009;4:1–6. Available from: http://www.perrigo.com/business/pdfs/Sec%20Artem%204.2.pdf.
- Shinde SG, Kadam V, Kapse GR, et al. A review on lozenges. Indo Am J Pharm Res 2014;4:9345–9349.
- Patel DM, Patel RJ, Shah HR, Patel CN. Formulation and evaluation of diphenhydramine hydrochloride lozenges for treatment of cough. World J Pharm Pharm Sci 2014;3:822–834.
- Ayverdi D, Ekim A, Ocakci AF. The effect of chewing gum on oral mucositis in children receiving chemotherapy. Health Sci J 2014;8:373–382.
- Jain V, Maheshwari R, Mahajan S. A review on lozenges. Brit Biomed Bull 2013;1:35–43.
- Madhav NV, Shakya AK, Shakya P, Singh K. Orotransmucosal drug delivery systems: a review. J Control Release 2009;140:2–11.
- Jones DS, Woolfson AD, Brown AF. Textural analysis and flow rheometry of novel, bioadhesive antimicrobial oral gels. Pharm Res 1997;14:450–457.
- Jones DS, Woolfson AD, Djokic J. Texture profile analysis of bioadhesive polymeric semisolids: mechanical characterization and investigation of interactions between formulation components. J Appl Polym Sci 1996;61:2229–2234.
- Marto J, Gouveia L, Jorge IM, et al. Starch-based pickering emulsions for topical drug delivery: a QbD approach. Colloid Surface B 2015;135:183–192.
- Khan K. The concept of dissolution efficiency. J Pharm Pharmacol 1975;27:48–49.
- ICH harmonized tripartite guideline validation of analytical procedures: methodology. ICHQ2B; 1996. Available from: http://www.ich.org.
- ICH harmonized tripartite guideline stability testing of new drugs and products. ICHQ1A(R2); 2003. Available from: http://www.ich.org.
- Matsui D, Barron A, Rieder MJ. Assessment of the palatability of antistaphylococcal antibiotics in pediatric volunteers. Ann Pharmacother 1996;30:586–588.
- Jones DS. Pharmaceutics – dosage form and design. London: Pharmaceutical Press; 2008.
- Schulze J, Sonnenborn U. Yeasts in the gut: from commensals to infectious agents. Dtsch Arztebl Int 2009;106:837–842.
- Sudbery PE. Growth of Candida albicans hyphae. Nat Rev Microbiol 2011;9:737–748.
- Buffo J, Herman MA, Soll DR. A characterization of pH-regulated dimorphism in Candida albicans. Mycopathologia 1984;85:21–30.
- Nadeem SG, Shafiq A, Hakim ST, et al. Effect of growth media, pH and temperature on yeast to hyphal transition in Candida albicans. Open J Med Microbiol 2013;3:185–192.
- Riley P, Glenny AM, Worthington HV, et al. Interventions for preventing oral mucositis in patients with cancer receiving treatment: oral cryotherapy. Cochrane Database Syst Rev 2015;12:CD011552.
- Reis CP, Roque LV, Baptista M, Rijo P. Innovative formulation of nystatin particulate systems in toothpaste for candidiasis treatment. Pharm Dev Technol 2015;21:282–287.
- Ellepola ANB, Samaranayake LP. The effect of limited exposure to antifungal agents on the germ tube formation of oral Candida albicans. J Oral Pathol Med 1998;27:213–219.
- Brito GN, Inocêncio AC, Querido SM, et al. In vitro antifungal susceptibility of Candida spp. oral isolates from HIV-positive patients and control individuals. Braz Oral Res 2011;25:28–33.
- Llabot JM, Manzo RH, Allemandi DA. Novel mucoadhesive extended release tablets for treatment of oral candidosis: “in vivo” evaluation of the biopharmaceutical performance. J Pharm Sci 2009;98:1871–1876.
- Aguiar MM, Albuquerque RP, Marinho DS, et al. Oral sustained release nystatin tablets for the treatment of oral candidiasis: formulation development and validation of UV spectrophotometric analytical methodology for content determination. Drug Dev Ind Pharm 2010;36:594–600.
- EMA note for guidance: specifications and control tests on the finished product. 3AQ11a; 1992. Available from: http://www.ema.europa.eu.
- Salgado AC, Rosa ML, Duarte MA, Almeida AJ. Stability of spironolactone in an extemporaneously prepared aqueous suspension: importance of microbiological quality of compounded pediatric formulations. Eur J Hosp Pharm Sci 2005;11:68–73.
- EMA guideline on pharmaceutical development of medicines for pediatric use. EMA/CHMP/QWP/805880/2012 rev. 2; 2012. Available from: http://www.ema.europa.eu.
- Cram A, Breitkreutz J, Desset-Brèthes S, et al. Challenges of developing palatable oral pediatric formulations. Int J Pharm 2009;365:1–3.
- Doyle C, Kushi LH, Byers T, et al. Nutrition and physical activity during and after cancer treatment: an American cancer society guide for informed choices. CA Cancer J Clin 2006;56:323–353.