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Ocular

Preparation of dexamethasone ophthalmic implants: a comparative study of in vitro release profiles

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Pages 218-224 | Received 18 Jul 2016, Accepted 06 Feb 2017, Published online: 30 Mar 2017

References

  • Arevalo JF. 2014. Diabetic macular edema: changing treatment paradigms. Curr Opin Ophthalmol. 25:502–507.
  • Barcia E, Herradon C, Herrero-Vanrell R. 2005. Biodegradable additives modulate ganciclovir release rate from PLGA microspheres destined to intraocular administration. LDDD. 2:184–193.
  • Bibliowicz J, Tittle RK, Gross JM. 2011. Toward a better understanding of human eye disease: insights from the Zebrafish, Danio rerio. In: Chang KT, Min KT, editors. Animal models of human disease. San Diego: Elsevier Academic Press Inc.; p. 287–330.
  • Boyer DS, Faber D, Gupta S, Patel SS, Tabandeh H, Li XY, Liu CC, Lou J, Whitcup SM; Ozurdex CHAMPLAIN Study Group. 2011. Dexamethasone intravitreal implant for treatment of diabetic macular edema in vitrectomized patients. Retina. 31:915–923.
  • Cabrera M, Yeh S, Albini TA. 2014. Sustained-release corticosteroid options. J Ophthalmol. 2014:164692.
  • Chang-Lin JE, Attar M, Acheampong AA, Robinson MR, Whitcup SM, Kuppermann BD, Welty D. 2011a. Pharmacokinetics and pharmacodynamics of a sustained-release dexamethasone intravitreal implant. Invest Ophthalmol Vis Sci. 52:80–86.
  • Chang-Lin JE, Burke JA, Peng Q, Lin T, Orilla WC, Ghosn CR, Zhang KM, Kuppermann BD, Robinson MR, Whitcup SM, Welty DF. 2011b. Pharmacokinetics of a sustained-release dexamethasone intravitreal implant in vitrectomized and nonvitrectomized eyes. Invest Ophthalmol Vis Sci. 52:4605–4609.
  • Chen H. 2015. Recent developments in ocular drug delivery. J Drug Target. 23:597–604.
  • Dash AK, Cudworth GC. 1998. Therapeutic applications of implantable drug delivery systems. J Pharmacol Toxicol Methods. 40:1–12.
  • de Smet MD. 2012. Corticosteroid intravitreal implants. In: Miserocchi E, Modorati G, Foster CS, editors. New treatments in noninfectious uveitis. Basel: Karger; p. 122–133.
  • Fialho SL, Behar-Cohen F, Cunha AS. 2008. Dexamethasone-loaded poly (ɛ-caprolactone) intravitreal implants: a pilot study. Eur J Pharm Biopharm. 68:637–646.
  • Fialho SL, Júnior ASC. 2007. Drug delivery systems for the posterior segment of the eye: fundamental basis and applications. Arq Bras Oftalmol. 70:173–179.
  • Gaudana R, Ananthula HK, Parenky A, Mitra AK. 2010. Ocular drug delivery. AAPS J. 12:348–360.
  • Hunter RS, Lobo AM. 2011. Dexamethasone intravitreal implant for the treatment of non-infections uveitis. Clin Ophthalmol. 5:1613–1621.
  • Maia J, Ribeiro MP, Ventura C, Carvalho RA, Correia IJ, Gil MH. 2009. Ocular injectable formulation assessment for oxidized dextran-based hydrogels. Acta Biomater. 5:1948–1955.
  • Miserocchi E, Fogliato G. 2013. Review on the worldwide epidemiology of uveitis. Eur J Ophthalmol. 23:705–717.
  • Resnikoff S, Pascolini D, Etya'ale D, Kocur I, Pararajasegaram R, Pokharel GP, Mariotti SP. 2004. Global data on visual impairment in the year 2002. Bull World Health Organ. 82:844–851.
  • Sapieha P, Hamel D. 2010. Proliferative retinopathies: angiogenesis that blinds. Int J Biochem Cell Biol. 42:5–12.
  • Short BG. 2008. Safety evaluation of ocular drug delivery formulations: techniques and practical considerations. Toxicol Pathol. 36:49–62.
  • Taylor SR, Isa H, Joshi L, Lightman S. 2010. New developments in corticosteroid therapy for uveitis. Ophthalmologica. 224:46–53.
  • van Wijngaarden P, Qureshi SH. 2008. Inhibitors of vascular endothelial growth factor (VEGF) in the management of neovascular age-related macular degeneration: a review of current practice. Clin Exp Optom. 91:427–437.
  • Zhang X, Zeng H. 2014. Diabetic macular edema: new concepts in patho-physiology and treatment. Cell Biosci. 4:27.

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