Advanced search
Publication Cover
Pharmaceutical Development and Technology Volume 23, 2018 - Issue 7: Issue Theme: Solubility enhancement and solid-state characterisation
Submit an article Journal homepage
212
Views
17
CrossRef citations to date
0
Altmetric
Research Article

Development of multiple-unit pellet system tablets by employing the SeDeM expert diagram system I: pellets with different sizes

Hannlie HammanCentre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South AfricaView further author information
,
Josias HammanCentre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South AfricaView further author information
,
Anita WesselsCentre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South AfricaView further author information
,
Jacques ScholtzCentre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South AfricaView further author information
&
Jan Harm SteenekampCentre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South AfricaCorrespondence[email protected]
View further author information
Pages 706-714 | Received 22 Feb 2017, Accepted 12 Jun 2017, Published online: 03 Jul 2017

References

  • Abdul S, Chandewar AV, Jaiswal SB. 2010. A flexible technology for modified-release drugs: multiple-unit pellet system (MUPS). J Controll Release. 147:2–16.
  • Aulton ME, Summers MP. 2013. Powders, granules and granulations. In: Aulton ME, Taylor KMG, editors. Aulton’s pharmaceutics: the design and manufacture of medicines. 4th ed. Edinburgh: Churchill Livingstone; p. 465–486.
  • Barakat NS, Ahmad AAE. 2008. Diclofenac sodium loaded-cellulose acetate butyrate: effect of processing variables on microparticles properties, drug release kinetics and ulcerogenic activity. J Microencapsul. 25:31–45.
  • British Pharmacopoeia Commission. 2015. Monographs. British pharmacopoeia, 2015. [Online]. London: The Stationary Office. Available from: https://www.pharmacopoeia.com/bp-2015/monographs
  • Dukić-Ott A, Remon JP, Foreman P, Vervaet C. 2007. Immediate release of poorly soluble drugs from starch-based pellets prepared via extrusion/spheronisation. Eur J Pharm Biopharm. 67:715–724.
  • Dukić-Ott A, Thommes M, Remon JP, Kleinebudde P, Vervaet C. 2009. Production of pellets via extrusion–spheronisation without the incorporation of microcrystalline cellulose: a critical review. Eur J Pharm Biopharm. 71:38–46.
  • Ghebre-Sellassie I, editor. 1994. Multiparticulate oral drug delivery. New York: M. Dekker; p. 480.
  • Jose S, Fangueiro JF, Smitha J, Cinu TA, Chacko AJ, Premaletha K, Souto EB. 2012. Cross-linked chitosan microspheres for oral delivery of insulin: Taguchi design and in vivo testing. Colloids Surf B Biointerfaces. 92:175–179.
  • Pagariya TP, Patil SB. 2013. Development and optimization of multiparticulate drug delivery system of alfuzosin hydrochloride. Colloids Surf B Biointerfaces. 102:171–177.
  • Pai R, Kohli K, Shrivastava B. 2012. Compression and evaluation of extended release matrix pellets prepared by the extrusion/spheronisation process into disintegrating tablets. Braz J Pharm Sci. 48:117–129.
  • Pérez P, Suñé-Negre JM, Miñarro M, Roig M, Fuster R, García-Montoya E, Hernández C, Ruhí R, Ticó JR. 2006. A new expert systems (SeDeM Diagram) for control batch powder formulation and preformulation drug products. Eur J Pharm Biopharm. 64:351–359.
  • Reddy S, Das P, Das H, Ghosh A. 2011. MUPS (multiple unit pellet system) tablets – a brief review. J Pharm Biomed Sci. 12:1–5.
  • Suñé-Negre JM, García E, Pérez PL, Aguilar Diaz JE, Carreras MR, Fuster R, Carmona MM, Tico JR. 2011a. SeDeM diagram: a new expert system for the formulation of drugs in solid form. In: Vizureanu P, editor. Expert systems for human, materials and automation. Croatia: InTech.
  • Suñé-Negre JM, Pérez-Lozano P, Miñarro M, Roig M, Fuster R, Hernández C, Ruhi R, Garcia-Montoya E, Tico JR. 2008. Application of the SeDeM Diagram and a new mathematical equation in the design of direct compression tablet formulation. Eur J Pharm Biopharm. 69:1029–1039.
  • Suñé-Negre JM, Pérez-Lozano P, Roig M, Fuster R, Hernández C, Ruhí R, García-Montoya E, Miñarro M, Ticó JR. 2011b. Optimization of parameters of the SeDeM Diagram Expert System: Hausner index (IH) and relative humidity (%RH). Eur J Pharm Biopharm. 79:464–472.
  • United States Pharmacopeia. 2015. United States Pharmacopeia and National Formulary (USP 39 - NF 34). 39th ed. Rockville (MD): The United States Pharmacopeial Convention.
  • Vervaet C, Baert L, Remon JP. 1995. Extrusion-spheronisation: a literature review. Int J Pharm. 116:131–146.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.