Advanced search
Publication Cover
Pharmaceutical Development and Technology Volume 25, 2020 - Issue 3
Submit an article Journal homepage
78
Views
1
CrossRef citations to date
0
Altmetric
Research Articles

Characterization and pharmacokinetic evaluation of microcomposite particles of alpha lipoic acid/hydrogenated colza oil obtained in supercritical carbon dioxide

Masatoshi HonjoFormulation Technology Group Functional Food Research Institute FANCL Research Institute FANCL Corporation, Yokohama, Japan; ;Research Institute of Composite Materials, Fukuoka University, Fukuoka, Japan; View further author information
,
Okuhara YasuhideFunctional Evaluation Group Health Science Research Center FANCL Research Institute FANCL Corporation, Yokohama, Japan; View further author information
,
Masayoshi YamadaMaterials Research Group Health Science Research Center FANCL Research Institute FANCL Corporation, Yokohama, Japan; View further author information
,
Sei HiguchiDepartment of Neuropharmacology Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan; View further author information
,
Kenji MishimaResearch Institute of Composite Materials, Fukuoka University, Fukuoka, Japan; ;Department of Chemical Engineering Faculty of Engineering, Fukuoka University, Fukuoka, Japan; Correspondence[email protected]
View further author information
,
Tanjina SharminResearch Institute of Composite Materials, Fukuoka University, Fukuoka, Japan; ;Department of Chemical Engineering Faculty of Engineering, Fukuoka University, Fukuoka, Japan; View further author information
,
Taku Michael AidaResearch Institute of Composite Materials, Fukuoka University, Fukuoka, Japan; ;Department of Chemical Engineering Faculty of Engineering, Fukuoka University, Fukuoka, Japan; View further author information
,
Takafumi KatoDepartment of Chemical Engineering Faculty of Engineering, Fukuoka University, Fukuoka, Japan; View further author information
,
Makoto MisumiDepartment of Electronics Engineering and Computer Science Faculty of Engineering, Fukuoka University, Fukuoka, Japan; View further author information
,
Tadashi SuetsuguDepartment of Electronics Engineering and Computer Science Faculty of Engineering, Fukuoka University, Fukuoka, Japan; View further author information
,
Hideaki OriiDepartment of Electrical Engineering Faculty of Engineering, Fukuoka University, Fukuoka, Japan; View further author information
,
Keiichi IrieDepartment of Neuropharmacology Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan; View further author information
,
Kazunori SanoDepartment of Neuropharmacology Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan; View further author information
,
Kenichi MishimaDepartment of Neuropharmacology Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan; View further author information
,
Tomomitsu SathoDepartment of Pharmaceutical Sciences, Fukuoka University, Fukuoka, Japan; View further author information
&
Takunori HaradaDepartment of Applied Chemistry Faculty of Engineering, Oita University, Oita, JapanView further author information
 show all
Pages 359-365 | Received 06 Oct 2017, Accepted 07 Jan 2019, Published online: 20 Dec 2019

References

  • Biewenga GP, Haenen G, Bast A. 1997. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol. 29:315–331.
  • Carey MC, Small DM, Bliss CM. 1983. Lipid digestion and absorption. Annu Rev Physiol. 45:651–677.
  • Fischman AJ, Alpert NM, Rubin RH. 2002. Pharmacokinetic imaging: a noninvasive method for determining drug distribution and action . Clin Pharmacokinet. 41:581–602.
  • Grasso S, Bramanti V, Tomassoni D, Bronzi D, Malfa G, Traini E, Napoli M, Renis M, Amenta F, Avola R. 2014. Effect of lipoic acid and α-glyceryl-phosphoryl-choline on astroglial cell proliferation and differentiation in primary culture. J Neurosci Res. 92:86–94.
  • Imamura M, Sato H. 2008. Development of sensory tests in selecting descriptive panelists for evaluating soy sauce and its related products. Japan Soc Food Sci Technol. 55:468–480.
  • Kate PS, Moreau RF, Smith EJ, Smith AR, Hagen TM. 2009. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta. 1790:1149–1160.
  • Larry AB. 2008. Chapter 1: clinical pharmacokinetic and pharmacodynamic concepts. In: Applied clinical pharmacokinetics. 2nd ed. New York (NY): McGraw-Hill Companies; p. 21–22.
  • Mishima K, Honjo M, Sharmin T, Ito S, Kawakami R, Kato T, Misumi M, Suetsugu T, Orii H, Kawano H, et al. 2015. Gas-saturated solution process to obtain microcomposite particles of alpha lipoic acid/hydrogenated colza oil in supercritical carbon dioxide. Pharm Dev Technol. 21(6):737–48.
  • Naito Y, Ikuta N, Okano A, Okamoto H, Nakata D, Terao K, Matsumoto K, Kajiwara N, Yasui H, Yoshikawa Y. 2015. Isomeric effects of anti-diabetic α-lipoic acid with γ-cyclodextrin. Life Sci. 136:73–78.
  • Packer L, Witt EH, Tritschler HJ. 1995. alpha-Lipoic acid as a biological antioxidant. Free Radic Biol Med. 19:227–250.
  • Peter G, Borbe HO. 1995. Absorption of [7,8-14C]-raca-lipoic acid from in situ ligated segments of the gastrointestinal tract of the rat. Arzneimittel-Forschung. 45:293–299.
  • Roberto M, Francesco Z, Giancarla S, Giuseppe S, Paola R, Eliano PN, Andrea M, Dario P, Gaetano AL, Giovanni G, et al. 2012. Effect of α-lipoic acid on platelet reactivity in type 1 diabetic patients. Diab Care. 35:196–197.
  • Rosenbaum SE. 2011. Basic pharmacokinetics and pharmacodynamics - an integrated textbook and computer simulations. Hoboken (NJ): John Wiley & Sons. ISBN 978-0-470-56906-1.
  • Ryota U, Hinako O, Naoko I, Keiji T, Takashi H. 2015. Enantioselective pharmacokinetics of α-lipoic acid in rats. Int J Mol Sci. 16:22781–22794.
  • Scott BC, Aruoma OI, Evans PJ, O'Neil C, Van der Vliet A, Cross CE, Tritschler H, Halliwell B. 1994. Lipoic and dihydrolipoic acids as antioxidants. A critical evaluation. Free Radic Res. 20:119–133.
  • Zamuner S, Di Iorio VL, Nyberg J, Gunn RN, Cunningham VJ, Gomeni R, Hooker AC. 2010. Adaptive-optimal design in PET occupancy studies. Clin Pharmacol Ther. 87:563–571.
  • Ziegler D, Ametov A, Barinov A, Dyck PJ, Gurieva I, Low PA, Munzel U, Yakhno N, Raz I, Novosadova M, et al. 2006. Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Diab Care. 29:2365–2370.
  • Ziegler D, Low PA, Litchy WJ, Boulton AJM, Vinik AI, Freeman R, Samigullin R, Tritschler H, Munzel U, Maus J, et al. 2011. Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial. Diab Care. 34:2054–2060.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.