Development and characterization of rapid dissolving ornidazole loaded PVP electrospun fibers

References

• Agarwal S, Wendorff JH, Greiner A. 2008. Use of electrospinning technique for biomedical applications. Polymer (Guildf). 49:5603–5621.
   Web of Science ®Google Scholar
• Asane GS, Rao YM, Bhatt JH, Shaikh KS. 2011. Optimization, characterisation and pharmacokinetic studies of mucoadhesive oral multiple unit systems of ornidazole. Sci Pharm. 79:181–196.
   PubMedGoogle Scholar
• Asmatulu R, Muppalla H, Veisi Z, Khan WS, Asaduzzaman A, Nuraje N. 2013. Study of hydrophilic electrospun nanofiber membranes for filtration of micro and nanosize suspended particles. Membranes (Basel). 3:375–388.
   PubMedGoogle Scholar
• Bakshi M, Singh B, Singh A, Singh S. 2001. The ICH guidance in practice: stress degradation studies on ornidazole and development of a validated stability-indicating assay. J Pharm Biomed Anal. 26:891–897.
   PubMed Web of Science ®Google Scholar
• Başaran E, Şenel B, Kirimlioğlu GY, Güven UM, Yazan Y. 2015. Ornidazole incorporated chitosan nanoparticles for ocular application. Lat Am J Pharm. 34:1180–1188.
   Web of Science ®Google Scholar
• Beglou MJ, Haghi AK. 2008. Electrospun biodegdadable and biocompatible natural nanofibers: a detailed review. Cellul Chem Technol. 42:441–462.
   Web of Science ®Google Scholar
• Bhardwaj N, Kundu SC. 2010. Electrospinning: a fascinating fiber fabrication technique. Biotechnol Adv. 28:325–347.
   PubMed Web of Science ®Google Scholar
• Cheng H, Yang X, Che X, Yang M, Zhai G. 2018. Biomedical application and controlled drug release of electrospun fibrous materials. Mater Sci Eng C Mater Biol Appl. 90:750–763.
   PubMed Web of Science ®Google Scholar
• Chivate A, Sargar V, Nalawade P, Tawde V. 2013. Formulation and development of oral dry suspension using taste masked Ornidazole particles prepared using Kollicoat(®) Smartseal 30 D. Drug Dev Ind Pharm. 39:1091–1097.
   PubMed Web of Science ®Google Scholar
• Deepak A, Goyal AK, Rath G. 2018. Nanofiber in transmucosal drug delivery. J Drug Deliv Sci Technol. 43:379–387.
   Web of Science ®Google Scholar
• Deka SR, Yadav S, Kumar D, Garg S, Mahato M, Sharma AK. 2017. Self-assembled dehydropeptide nano carriers for delivery of ornidazole and curcumin. Colloids Surf B Biointerfaces. 155:332–340.
   PubMed Web of Science ®Google Scholar
• Esentürk İ, Sedef Erdal M, Güngör S. 2016. Electrospinning method to produce drug-loaded nanofibers for topical/transdermal drug delivery applications. İstanbul Ecz Fak Derg/J Fac Pharm Istanbul [Internet]. 46:49–69. Available from: http://dergipark.gov.tr/download/article-file/266761
   Web of Science ®Google Scholar
• Fonseca-Santos B, Chorilli M. 2018. An overview of polymeric dosage forms in buccal drug delivery: state of art, design of formulations and their in vivo performance evaluation. Mater Sci Eng C. 86:129–143.
   PubMed Web of Science ®Google Scholar
• Forward KM, Flores A, Rutledge GC. 2013. Production of core/shell fibers by electrospinning from a free surface. Chem Eng Sci. 104:250–259.
   Web of Science ®Google Scholar
• Gajewski A. 2017. A couple new ways of surface tension determination. Int J Heat Mass Transf. 115:909–917.
   Web of Science ®Google Scholar
• Gökmeşe F, Uslu I, Aytimur A. 2013. Preparation and characterization of PVA/PVP nanofibers as promising materials for wound dressing. Polym - Plast Technol Eng. 52:1259–1265.
   Web of Science ®Google Scholar
• Hu X, Liu S, Zhou G, Huang Y, Xie Z, Jing X. 2014. Electrospinning of polymeric nanofibers for drug delivery applications. J Control Release. 185:12–21.
   PubMed Web of Science ®Google Scholar
• Huang S, Zhou L, Li M-C, Wu Q, Kojima Y, Zhou D. 2016. Preparation and properties of electrospun poly (vinyl pyrrolidone)/cellulose nanocrystal/silver nanoparticle composite fibers. Materials (Basel) [Internet]. 9:523. Available from: http://www.mdpi.com/1996-1944/9/7/523
   PubMed Web of Science ®Google Scholar
• Jia Y, Huang G, Dong F, Liu Q, Nie W. 2016. Preparation and characterization of electrospun poly(ε-caprolactone)/poly(vinyl pyrrolidone) nanofiber composites containing silver particles. Polym Compos. 37:2847–2854.
   Web of Science ®Google Scholar
• Joshi D, Garg T, Goyal AK, Rath G. 2015. Development and characterization of novel medicated nanofibers against periodontitis. Curr Drug Deliv. 12:564–577.
   PubMed Web of Science ®Google Scholar
• Kenry, Lim CT. 2017. Nanofiber technology: current status and emerging developments. Prog Polym Sci. 70:1–17.
   Web of Science ®Google Scholar
• Kraisit P, Limmatvapirat S, Luangtana-Anan M, Sriamornsak P. 2018. Buccal administration of mucoadhesive blend films saturated with propranolol loaded nanoparticles. Asian J Pharm Sci [Internet]. 13:34–43.
   PubMed Web of Science ®Google Scholar
• Krishnaiah YSR, Indira Muzib Y, Srinivasa Rao G, Bhaskar P, Satyanarayana V. 2003. Studies on the development of colon targeted oral drug delivery systems for ornidazole in the treatment of amoebiasis. Drug Deliv. 10:111–117.
   PubMed Web of Science ®Google Scholar
• Liu R, Li N, Liu N, Zhou X, Dong Z, Wen X, Liu L. 2012. Effects of systemic ornidazole, systemic and local compound ornidazole and pefloxacin mesylate on experimental periodontitis in rats. Med Sci Monit. 18:BR95–BR102. Available from: http://www.medscimonit.com/abstract/index/idArt/882514
   PubMed Web of Science ®Google Scholar
• Lubasova D, Niu H, Zhao X, Lin T. 2015. Hydrogel properties of electrospun polyvinylpyrrolidone and polyvinylpyrrolidone/poly(acrylic acid) blend nanofibers. RSC Adv. 5:54481–54487.
   Web of Science ®Google Scholar
• Luckey TD. 2006. Low dose irradiation as a treatment for gingivitis. Med Hypotheses. 66:695–697.
   PubMed Web of Science ®Google Scholar
• Marques MRC, Loebenberg R, Almukainzi M. 2011. Simulated biological fluids with possible application in dissolution testing. Dissolution Technol. 18:15–28.
   Web of Science ®Google Scholar
• Mirmohammad Sadeghi S, Vaezi M, Kazemzadeh A, Jamjah R. 2018. Morphology enhancement of TiO2/PVP composite nanofibers based on solution viscosity and processing parameters of electrospinning method. J Appl Polym Sci. 135:46337.
   Web of Science ®Google Scholar
• Morales JO, Brayden DJ. 2017. Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles. Curr Opin Pharmacol. 36:22–28.
   PubMed Web of Science ®Google Scholar
• Patel VF, Liu F, Brown MB. 2011. Advances in oral transmucosal drug delivery. J Control Release. 153:106–116.
   PubMed Web of Science ®Google Scholar
• Patel B, Shah S, Kumar S. 2014. Evaluation of ornidazole gel as an adjunct to the phase I therapy. Adv Hum Biol. 4:21–25.
   Google Scholar
• Rajesh P, Gunasekaran S, Gnanasambandan T, Seshadri S. 2016. Experimental and theoretical study of ornidazole. Spectrochim Acta - Part A Mol Biomol Spectrosc. 153:496–504.
   PubMed Web of Science ®Google Scholar
• Rath G, Hussain T, Chauhan G, Garg T, Kumar Goyal A. 2016. Fabrication and characterization of cefazolin-loaded nanofibrous mats for the recovery of post-surgical wound. Artif Cells Nanomed Biotechnol. 44:1783–1792.
   PubMed Web of Science ®Google Scholar
• Rawat S, Warade S, Lahoti S. 2010. In situ gel formulation of ornidazole for the treatment of periodontal disease. Curr Pharma Res. 1:60–69.
   Google Scholar
• Remeth Jacky Dias Havaldar VD, Ghorpade VS, Mali KK, Gaikwad VK, Kumbhar DM. 2016. Development and evaluation of in-situ gel containing ornidazole loaded microspheres for treatment of periodontitis. J App Pharm Sci. 6:200–209.
   Google Scholar
• Roy SK, Prabhakar B. 2010. Bioadhesive polymeric platforms for transmucosal drug delivery systems - a review. Trop J Pharm Res. 9:91–104.
   Web of Science ®Google Scholar
• Salamat-Miller N, Chittchang M, Johnston TP. 2005. The use of mucoadhesive polymers in buccal drug delivery. Adv Drug Deliv Rev. 57:1666–1691.
   PubMed Web of Science ®Google Scholar
• Santocildes-Romero ME, Hadley L, Clitherow KH, Hansen J, Murdoch C, Colley HE, Thornhill MH, Hatton PV. 2017. Fabrication of electrospun mucoadhesive membranes for therapeutic applications in oral medicine. ACS Appl Mater Interfaces. 9:11557–11567.
   PubMed Web of Science ®Google Scholar
• Shahreen L, Chase GG. 2015. Effects of electrospinning solution properties on formation of beads in TiO2 fibers with PdO particles. J Eng Fiber Fabr [Internet]. 10:155892501501000. Available from: http://journals.sagepub.com/doi/10.1177/155892501501000308
   Web of Science ®Google Scholar
• Singh B, Garg T, Goyal AK, Rath G. 2016. Development, optimization, and characterization of polymeric electrospun nanofiber: a new attempt in sublingual delivery of nicorandil for the management of angina pectoris. Artif Cells Nanomed Biotechnol. 44:1498–1507.
   PubMed Web of Science ®Google Scholar
• Sriyanti I, Edikresnha D, Munir MM, Rachmawati H, Khairurrijal. 2016. Electrospun polyvinylpyrrolidone (PVP) nanofiber mats loaded by Garcinia mangostana L. extracts. Mater Sci Forum [Internet]. 880:11–14. Available from: https://www.scientific.net/MSF.880.11
   Google Scholar
• Stepanyan R, Subbotin AV, Cuperus L, Boonen P, Dorschu M, Oosterlinck F, Bulters M. 2016. Nanofiber diameter in electrospinning of polymer solutions: model and experiment. Polym (UK). 97:428–439.
   Web of Science ®Google Scholar
• Suknuntha K, Tantishaiyakul V, Worakul N, Taweepreda W. 2011. Characterization of muco- and bioadhesive properties of chitosan, PVP, and chitosan/PVP blends and release of amoxicillin from alginate beads coated with chitosan/PVP. Drug Dev Ind Pharm [Internet]. 37:408–418. Available from: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79953244162&partnerID=40&dd2aab80a5b27a83ce99a8e0339be41e
   PubMed Web of Science ®Google Scholar
• Tarus B, Fadel N, Al-Oufy A, El-Messiry M. 2016. Effect of polymer concentration on the morphology and mechanical characteristics of electrospun cellulose acetate and poly (vinyl chloride) nanofiber mats. Alexandria Eng J. 55:2975–2984.
   Web of Science ®Google Scholar
• Tavakkol E, Tavanai H, Abdolmaleki A, Morshed M. 2017. Production of conductive electrospun polypyrrole/poly(vinyl pyrrolidone) nanofibers. Synth Met. 231:95–106.
   Web of Science ®Google Scholar
• Thakkar S, Misra M. 2017. Electrospun polymeric nanofibers: new horizons in drug delivery. Eur J Pharm Sci. 107:148–167. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0928098717304001
   PubMed Web of Science ®Google Scholar
• Thenmozhi S, Dharmaraj N, Kadirvelu K, Kim HY. 2017. Electrospun nanofibers: new generation materials for advanced applications. Mater Sci Eng B [Internet]. 217:36–48. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0921510717300016
   Web of Science ®Google Scholar
• Tort S, Acartürk F, Beşikci A. 2017. Evaluation of three-layered doxycycline-collagen loaded nanofiber wound dressing. Int J Pharm. 529:642–653.
   PubMed Web of Science ®Google Scholar
• Tort H, Oktay EA, Tort S, Bayar GR, Toksoy Topcu F, Kilic E, Acarturk F. 2017. Evaluation of ornidazole-loaded nanofibers as an alternative material for direct pulp capping. J Drug Deliv Sci Technol. 41:317–324.
   Web of Science ®Google Scholar
• Tort S, Demiröz FT, Yıldız S, Acartürk F. 2019. Effects of UV exposure time on nanofiber wound dressing properties during sterilization. J Pharm Innov [Internet]. Available from: http://link.springer.com/10.1007/s12247-019-09383-7
   PubMedGoogle Scholar
• Wang G, Yu D, Kelkar AD, Zhang L. 2017. Electrospun nanofiber: emerging reinforcing filler in polymer matrix composite materials. Prog Polym Sci. 75:73–107.
   Web of Science ®Google Scholar
• Wust J. 1977. Susceptibility of anaerobic bacteria to metronidazole, ornidazole, and tinidazole and routine susceptibility testing by standardized methods. Antimicrob Agents Chemother [Internet]. 11:631–637. Available from: http://aac.asm.org/cgi/doi/10.1128/AAC.11.4.631
   PubMed Web of Science ®Google Scholar
• Yadav SK, Mishra B. 2016. Preformulation studies on combination of ornidazole and doxycycline in pharmaceutical dosage forms: infra-red spectroscopy and simultaneous ultra-violet method development. J Chem Pharm Res [Internet]. 8:564–573. Available from: http://www.jocpr.com/articles/preformulation-studies-on-combination-of-ornidazole-and-doxycycline-in-pharmaceutical-dosage-forms-infrared-spectroscopy.pdf
   Google Scholar
• Zhang C, Liu Y, Li W, Gao P, Xiang D, Ren X, Liu D. 2018. Mucoadhesive buccal film containing ornidazole and dexamethasone for oral ulcers: in vitro and in vivo studies. Pharm Dev Technol. 1–9.
   PubMed Web of Science ®Google Scholar
• Zong X, Kim K, Fang D, Ran S, Hsiao BS, Chu B. 2002. Structure and process relationship of electrospun bioabsorbable nanofiber membranes. Polymer (Guildf). 43:4403–4412.
   Web of Science ®Google Scholar