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Research Article

A Study on Microwave-Induced Melt Granulation in a Single Pot High Shear Processor

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Pages 401-411 | Received 23 Nov 2007, Accepted 07 Apr 2008, Published online: 20 Oct 2008

REFERENCES

  • T Schaefer, B Taagegaard, LJ Thomsen, and HG Kristensen. (1993). Melt pelletization in a high shear mixer. IV. Effects of process variables in a laboratory scale mixer. Eur. J. Pharm. Sci 1:125–131.
  • T Schaefer, B Taagegaard, LJ Thomsen, and HG Kristensen. (1993). Melt pelletization in a high shear mixer. V. Effects of apparatus variables. Eur. J. Pharm. Sci 1:133–141.
  • TW Wong, WS Cheong, and PWS Heng. Melt granulation and pelletization Handbook of Pharmaceutical Granulation Technology 2nd DM Parikh. Taylor and Francis Group, AbingdonUK, (2005)385–406.
  • MK Doelling, and RA Nash. (1992). The development of a microwave fluid bed processor. II. Drying performance and physical characteristics of typical pharmaceutical granulations. Pharm. Res 9:1493–1501.
  • H Vromans. (1994). Microwave drying of pharmaceutical excipients: Comparison with conventional conductive drying. Eur. J. Pharm. Biopharm 40:333–336.
  • TK Mandal. (1995). Evaluation of microwave drying for pharmaceutical granulations. Drug Dev. Ind. Pharm 21:1683–1688.
  • Á Kelen, E Pallai-Varsanyi, S Ress, T Nagy, and K Pintye-Hodi. (2006). Practical method of choosing diluent that ensures the best temperature uniformity in the case of pharmaceutical microwave vacuum drying of a heat sensitive product. Eur. J. Pharm. Biopharm 62:101–109.
  • CM McLoughlin, WAM McMinn, and TRA Magee. Physical and dielectric properties of pharmaceutical powders Powder Technol. . , (2003)13440–51.
  • SO Nelson. (1994). Measurement of microwave dielectric properties of particulate materials. J. Food Eng 21:365–384.
  • RF Schiffmann. Microwave and dielectric drying Handbook of Industrial Drying AS Mujumdar. Marcel Dekker, New York, (1995)345–372.
  • F Içier, and T Baysal. Dielectric properties of food materials. 1. Factors affecting and industrial uses Crit. Rev. Food Sci. . , (2004)44465–471.
  • G Betz, PJ Bürgin, and H Leuenberger. (2004). Power consumption measurement and temperature recording during granulation. Int. J. Pharm 272:137–149.
  • Operating Manual for UltimaProTM10L, Machine No. 04V0010005. Collette: Belgium, 2005, Chapter 2.
  • PWS Heng, TW Wong, JJ Shu, and LSC Wan. (1999). A new method for the control of size of pellets in the melt pelletization process with a high shear mixer. Chem. Pharm. Bull 47:633–638.
  • PR Mort. Scale up of binder agglomeration processes Powder Technol. . , (2005)15086–103.
  • KH Esbensen. Principal Component Analysis (PCA) – Introduction Multivariate Data Analysis In Practice – An Introduction to Multivariate Data Analysis and Experimental Design 5th KH Esbensen. Camo Software AS, OsloNorway, (2001)19–74.
  • T Schaefer, and C Mathiesen. (1996). Melt pelletization in a high shear mixer. VII. Effects of product temperature. Int. J. Pharm 134:105–117.
  • T Schaefer, P Holm, and HG Kristensen. Melt pelletization in a high shear mixer. II. Power consumption and granule growth Acta Pharm. Nordica. . , (1992)4141–148.
  • T Schaefer, P Holm, and HG Kristensen. Melt pelletization in a high shear mixer. III. Effects of lactose quality Acta Pharm. Nordica. . , (1992)4245–252.
  • HG Kristensen, and T Schaefer. A review of pharmaceutical wet granulation Drug Dev. Ind. Pharm. . , , (1987)13803–872.
  • MJ Cliff. Granulation end point and automated process control of mixer granulators: Part I. Pharm. Technol. . , (1990)14112–132.
  • V Covari, WC Fry, WL Seibert, and L Augsburger. Instrumentation of a high shear mixer: evaluation and comparison of a new capacitive sensor, a watt meter and a strain gauge torque sensor for wet granulation monitoring Pharm. Res. . , (1992)91524–1533.
  • GJB Horsthuis, JAH Van Laarhoven, RCBM Van Rooij, and H Vromans. (1993). Studies on upscaling parameters of the Gral high shear granulation process. Int. J. Pharm 92:143–150.
  • T Schaefer. (1996). Melt pelletization in a high shear mixer. X. Agglomeration of binary mixtures. Int. J. Pharm 139:149–159.
  • A Faure, P York, and RC Rowe. (2001). Process control and scale-up of pharmaceutical wet granulation processes: a review. Eur. J. Pharm. Biopharm 52:269–277.
  • M Araszkiewicz, A Koziol, A Oskwarek, and M Lupinski. (2004). Microwave drying of porous materials. Dry Technol 22:2331–2341.
  • M Araszkiewicz, A Koziol, A Lupinska, and M Lupinski. (2006). Temperature distribution in a single sphere dried with microwaves and hot air. Dry Technol 24:1381–1386.
  • Á Kelen, S Ress, T Nagy, E Pallai-Varsanyi, and K Pintye-Hodi. (2006). “3D layered thermography” method to map the temperature distribution of a free flowing bulk in case of microwave drying. Int. J. Heat Mass Tran 49:1015–1021.
  • WAM McMinn, CM McLoughlin, and TRA Magee. (2006). Temperature characteristics of pharmaceutical powders during microwave drying. Dry Technol 24:571–580.

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