Mutagen formation in a model beef boiling system II. Effects of proteolysis and comparison of soluble fractions from several protein sources

References

• Ambler , RP . 1967 . “ Enzymatic hydrolysis with carboxypeptidases; Carboxypeptidases A and B. ” . In “Methods in Enzymology” , Edited by: Hirs , CHW . Vol. 11 , 155 – 166 . 436 – 445 . New York and London : Academic Press .
   Google Scholar
• Ames , BN , McCann , J and Yamasaki , E . 1975 . Methods for detecting carcinogens and mutagens with the Salmonella mammalian‐microsome mutagenicity test . Mutat Res , 31 : 347 – 364 .
   PubMed Web of Science ®Google Scholar
• Ashoor , SH , Dietrich , RA , Chu , FS and Pariza , MW . 1980 . Proline enhances mutagen formation in ground beef during frying . Life Sci , 26 : 1801 – 1805 .
   PubMedGoogle Scholar
• Barnes , WS , Maher , JC and Weisburger , JH . 1983 . High‐pressure liquid chromatographic method for the analysis of 2‐amino‐3‐methylimidazo[4,5‐f]quinoline, a mutagen formed during the cooking of food . J Agric Food Chem , 31 : 883 – 886 .
   Web of Science ®Google Scholar
• Bjarnason , J and Carpenter , KJ . 1970 . Mechanisms of heat damage in proteins 2. Chemical changes in pure proteins . Br 3 Nutrition , 24 : 313 – 329 .
   PubMed Web of Science ®Google Scholar
• Bjeldanes , LF , Morris , MM , Felton , JS , Healy , S , Stuermer , D , Berry , P , Timourian , H and Hatch , FT . 1982 . Mutagens from the cooking of food II. Survey by Ames/Salmonella test of mutagen formation in the major protein‐rich foods of the American diet . Food Chem Toxicol , 20 : 357 – 363 .
   PubMed Web of Science ®Google Scholar
• Bjeldanes , LF , Morris , MM , Felton , JS , Healy , S , Stuermer , D , Berry , P , Timourian , H and Hatch , FT . 1982 . Mutagens from the cooking of food III. Survey by Ames/Salmonella test of mutagen formation in secondary sources of cooked dietary protein . Food Chem Toxicol , 20 : 365 – 369 .
   PubMed Web of Science ®Google Scholar
• Bjeldanes , LF , Morris , MM , Timourian , H and Hatch , FT . 1983 . Effects of meat composition and cooking conditions on mutagen formation in fried ground beef . J Agr Food Chem , 31 : 18 – 21 .
   PubMed Web of Science ®Google Scholar
• Committee on Diet, Nutrition, and Cancer NRC . 1982 . “Diet, Nutrition, and Cancer.” , 1 – 10 . Washington, D.C. : National Academy Press . Ch. 13
   Google Scholar
• Commoner , B , Vithayathil , AJ , Dolara , P , Nair , S , Madyastha , P and Cuca , GC . 1978 . Formation of mutagens in beef and beef extract during cooking . Science , 201 : 913 – 916 .
   PubMed Web of Science ®Google Scholar
• Dayhoff , MO . 1972 . “Atlas of Protein Sequence and Structure” , Vol. 5 , D – 136 . Washington, D.C. : National Biomedical Research Foundation .
   Google Scholar
• Dayhoff , MO . 1976 . “Atlas of Protein Sequence and Structure” , Vol. 5 , 267 Washington, D.C. : National Biomedical Research Foundation . Suppl. 2.
   Google Scholar
• Doll , R . 1978 . Nutrition and Cancer; a review . Nutrition and Cancer , 1 : 35 – 45 .
   Google Scholar
• Felton , JS , Knize , M , Wood , C , Wuebbles , B , Healy , SK , Stuermer , DH , Bjeldanes , LF , Kimble , BJ and Hatch , FT . 1984 . Isolation and characterization of new mutagens from fried ground beef . Carcinogenesis , 5 : 95 – 102 .
   PubMed Web of Science ®Google Scholar
• Gray , JI and Morton , ID . 1981 . Some toxic compounds produced in food by cooking and processing . J Human Nutrition , 35 : 5 – 23 .
   PubMedGoogle Scholar
• Haenszel , W , Berg , JW , Segi , M , Kurihara , to and Locke , FB . 1973 . Large‐bowel cancer in Hawaiian Japanese . J Natl Cancer Inst , 51 : 1765 – 1779 .
   PubMed Web of Science ®Google Scholar
• Haenszel , W and Kurihara , M . 1968 . Studies of Japanese migrants. I. Mortality from cancer and other diseases among Japanese in the United States . J Natl Cancer Inst , 40 : 43 – 68 .
   PubMed Web of Science ®Google Scholar
• Hargraves , WA and Pariza , MW . 1983 . Purification and mass spectra characterization of bacterial mutagens from commercial beef extract . Cancer Res , 43 : 1467 – 1472 .
   PubMed Web of Science ®Google Scholar
• Hayatsu , H , Matsui , Y , Ohara , Y , Oka , T and Hayatsu , T . 1983 . Characterization of mutagenic fractions in beef extract and cooked ground beef. Use of blue‐cotton for efficient extraction . Gann , 74 : 472 – 482 .
   PubMedGoogle Scholar
• Khan , AW and Cowen , DC . 1977 . Rapid estimation of muscle proteins in beef‐vegetable protein mixtures . J Agric Food Chem , 25 : 236 – 238 .
   PubMed Web of Science ®Google Scholar
• Krone , CA and Iwaoka , WT . 1981 . Mutagen formation during the cooking of fish . Cancer Lett , 14 : 93 – 99 .
   PubMedGoogle Scholar
• Labuza , TP , Warren , RM and Warmbier , HC . 1976 . “ The physical aspects with respect to water and non‐enzymatic browning ” . In “Protein Crosslinking; Nutritional and Medical Consequences.” , Edited by: Friedman , M . 379 – 418 . New York and London : Plenum Press .
   Google Scholar
• Lowry , OH , Rosebrough , NJ , Farr , AL and Randall , RJ . 1951 . Protein measurement with the Folin phenol reagent . J Biol Chem , 193 : 265 – 275 .
   PubMed Web of Science ®Google Scholar
• Macy , RL Jr. , Naumann , HD and Bailey , ME . 1964 . Water‐soluble flavor and odor precursors of meat. II. Effects of heating on amino nitrogen constituents and carbohydrates in lyophilized diffusates from aqueous extracts of beef, pork, and lamb . J Food Sci , 29 : 142 – 148 .
   Web of Science ®Google Scholar
• Matsumoto , T , Yoshida , D , Mizusaki , S and Okamoto , H . 1977 . Mutagenic activity of amino acid pyroiysates in Salmonella typhimurium TA98 . Mutat Res , 48 : 279 – 286 .
   PubMed Web of Science ®Google Scholar
• Matsumoto , T , Yoshida , D , Mizusaki , J and Okamoto , H . 1978 . Mutagenicities of the pyrolyzates of peptides and proteins . Mutat Res , 56 : 281 – 288 .
   PubMed Web of Science ®Google Scholar
• Matsushima , T and Wang , Y‐M . 1982 . “ Mechanisms of conversion of food components to mutagens and carcinogens ” . In “Molecular Interrelations of Nutrition and Cancer.” , Edited by: Arnott , MS and van Eys , J . 35 – 42 . New York : Raven Press .
   Google Scholar
• Matsushima , T and Sugimura , T. 1981 . “ Mutagen‐carcinogens in amino acid and protein pyroiysates and in cooked food ” . In “Progress in Mutation Research” , Edited by: Kappas , A . Vol. 2 , 49 – 56 . Amsterdam, Oxford, and New York : Elsevier/North‐Holland Biomedical Press .
   Google Scholar
• Mauron , J . 1981 . “ The Maillard reaction in food; A critical review from the nutritional standpoint ” . In “Progress in Food and Nutrition Science” , Edited by: Eriksson , C . Vol. 5 , 5 – 35 . Great Britain : Pergamon Press Ltd. .
   Google Scholar
• McCann , J and Ames , BN . 1976 . Detection of carcinogens as mutagens in the Salmonella/microsome test: Assay of 300 chemicals; discussion . Proc Natl Acad Sci USA , 73 : 950 – 954 .
   PubMed Web of Science ®Google Scholar
• McCann , J , Choi , E , Yamasaki , E and Ames , BN . 1975 . Detection of carcinogens as mutagens in the Salmonella/microsome test: Assay of 300 chemicals . Proc Natl Acad Sci USA , 72 : 5135 – 5139 .
   PubMed Web of Science ®Google Scholar
• Pariza , MW . 1982 . Mutagens in heated foods . Food Technology , March : 53 – 56 .
   Google Scholar
• Pariza , MW , Ashoor , SH , Ruane , DJ , Hugdahl , MB and Chu , FS . 1980 . Formation of mutagens in cooked beef and in model systems . Proc Am Assoc Cancer Res , 21 : 87 (Abstract)
   Google Scholar
• Phillips , RL . 1975 . Role of life style and diet habits in the risk of cancer among Seventh‐Day Adventists . Cancer Res , 35 : 3515 – 3522 .
   Google Scholar
• Purchase , IFH , Longstaff , E , Ashby , J , Styles , JA , Anderson , D , Lefevre , PA and Westwood , FR . 1978 . An evaluation of 6 short term tests for detecting organic chemical carcinogens . Br J Cancer , 37 : 873 – 859 .
   PubMed Web of Science ®Google Scholar
• Reddy , BS , Cohen , LA , McCoy , GD , Hill , P , Weisburger , JH and Wynder , EL . 1980 . “ Nutrition and its relationship to cancer ” . In “Advances in Cancer Research” , Edited by: Klein , G and Weinhouse , S . Vol. 32 , 237 – 345 . New York and London : Academic Press .
   Google Scholar
• Rogers , AM and Shibamoto , T . 1982 . Mutagenicity of the products obtained from heated milk systems . Food Chem Toxicol , 20 : 259 – 263 .
   PubMedGoogle Scholar
• Shibamoto , T . 1982 . Occurrence of mutagenic products in browning model systems . Food Technology , March : 59 – 62 .
   Google Scholar
• Smyth , DG . 1967 . “ Techniques in enzyme hydrolysis ” . In “Methods in Enzymology” , Edited by: Hirs , CHW . Vol. 11 , 214 – 231 . New York and London : Academic Press .
   Google Scholar
• Spingarn , NE and Garvie , CT . 1979 . Formation of mutagens in sugar‐ammonia model systems . J Agric Food Chem , 27 : 1319 – 1321 .
   PubMed Web of Science ®Google Scholar
• Sugimura , T and Wang , Y‐M . 1982 . “ Tumor initiators and promoters associated with ordinary foods ” . In “Molecular Interrelations of Nutrition and Cancer.” , Edited by: Arnott , MS and van Eys , J . 3 – 24 . New York : Raven Press .
   Google Scholar
• Sugimura , T and Nagao , M . 1979 . “ Mutagenic factors in cooked foods ” . In “CRC Critical Reviews in Toxicology.” , Edited by: Goldberg , L . Vol. 6 , 189 – 209 . West Palm Beach : CRC Press .
   Google Scholar
• Sugimura , T , Nagao , M and Wakabayashi , K . 1981 . Mutagenic heterocyclic amines in cooked food . IARC Scientific Publication , 4 (40) : 251 – 267 .
   Google Scholar
• Sugimura , T and Sato , S . 1983 . Mutagens‐carcinogens in foods . Cancer Res , 43 (Suppl) : 2415s – 2421s .
   PubMed Web of Science ®Google Scholar
• Sugimura , T , Sato , S , Nagao , M , Yahagi , T , Matsushima , T , Takeuchi , M and Kawachi , T . 1976 . “ Overlapping of carcinogens and mutagens ” . In “Fundamentals in Cancer Prevention.” , Edited by: Magee , PN , Takayama , S , Sugimura , T and Matsushima , T . 191 – 213 . Baltimore, London, and Tokyo : University Park Press .
   Google Scholar
• Taylor , RT , Fultz , E and Shore , V . 1981 . Food mutagen formation in model boiling systems . Environ Mutagenesis , 3 : 349 (Abstract)
   Google Scholar
• Taylor , RT , Fultz , E and Shore , V . 1983 . Mutagen formation in a model beef boiling system I. Conditions with a soluble beef derived fraction . J Environ Sci Health , companion paper
   Google Scholar
• Taylor , RT , Shore , V and Fultz , E . 1982 . Mutagen formation in a model beef boiling system: Stimulation studies with amino acids and other agents . Environ Mutagenesis , 4 : 368 (Abstract)
   Google Scholar
• Turesky , RJ , Wishnok , JS , Tannenbaum , SR , Pfund , RA and Buchi , GH . 1983 . Qualitative and quantitative characterization of mutagens in commercial beef extract . Carcinogenesis , 4 : 863 – 866 .
   PubMed Web of Science ®Google Scholar
• Uyeta , M , Kanada , T , Mazaki , M and Tane , S . 1978 . Studies on mutagenicity of food (I) . J Food Hyg Soc Japan , 19 : 216 – 223 .
   Google Scholar
• Uyeta , M , Kanada , T , Mazaki , M , Tane , S and Takahashi , S . 1979 . “ Assaying mutagenicity of food pyrolysis products using the Ames test ” . In “Naturally Occurring Carcinogens‐Mutagens and Modulators of Carcinogenesis.” , Edited by: Miller , EC , Miller , JA , Hirono , I , Sugimura , T and Takeyama , S . 169 – 176 . Baltimore and Tokyo : Univ Park/Japan Sci Soc Press .
   Google Scholar
• Weisburger , JH and Spingarn , NE . 1979 . “ Mutagens as a function of mode of cooking of meats ” . In “Naturally Occurring Carcinogens‐Mutagens and Modulators of Carcinogenesis.” , Edited by: Miller , EC , Miller , JA , Hirono , I , Sugimura , T and Takeyama , S . 177 – 184 . Baltimore and Tokyo : Univ Park/Japan Sci Soc Press .
   Google Scholar
• Wynder , EL and Gori , GB . 1977 . Contribution of environment to cancer incidence; an epidemiologic exercise . J Natl Cancer Inst , 58 : 825 – 832 .
   PubMed Web of Science ®Google Scholar
• Yoshida , D and Fukuhara , Y . 1982 . Formation of mutagens by heating creatine and amino acids . Agric Biol Chem , 46 : 1069 – 1070 .
   Web of Science ®Google Scholar
• Yoshida , D and Okamoto , H . 1980 . Formation of mutagens by heating creatine and glucose . Biochem Biophys Res Commun , 96 : 844 – 847 .
   PubMedGoogle Scholar
• Yoshida , D and Okamoto , H . 1980 . Formation of mutagens by heating creatine or amino acids with addition of fatty acids . Agric Biol Chem , 44 : 3025 – 3027 .
   Web of Science ®Google Scholar
• Author to whom correspondence should be addressed.
   Google Scholar