Publication Cover
Journal of Environmental Science and Health, Part A
Toxic/Hazardous Substances and Environmental Engineering
Volume 45, 2010 - Issue 12
193
Views
8
CrossRef citations to date
0
Altmetric
Original Articles

Chloroform distribution and accumulation by combined inhalation plus oral exposure routes in rats

, , , , , & show all
Pages 1616-1624 | Received 25 Mar 2010, Published online: 20 Aug 2010

References

  • International Agency for Research on Cancer (IARC) . 1999 . Some chemicals that cause tumours of the kidney or urinary bladder in rodents and some other substances . IARC Monogr. Eval. Carcinog. Risks Hum. , 73 : 131 – 182 .
  • 1997 . ATSDR Toxicological Profile for Chloroform. ATSDR , Atlanta : Agency for Toxic Substances and Disease Registry . www.atsdr.cdc.gov/toxprofiles/tp6.html (accessed March, 2010)
  • Ministry of the Environment Government of Japan . 2008 . Pollutant Release and Transfer Register , Tokyo : Environmental Health and Safety Division, Environmental Health Department, Ministry of the Environment Government of Japan . www.env.go.jp/en/chemi/prtr/prtr.html (accessed March, 2010)
  • Andelman , J. B. 1985 . Human exposures to volatile halogenated organic chemicals in indoor and outdoor air . Environ. Health Perspect. , 62 : 313 – 318 .
  • Ministry of the Environment Government of Japan . 2003 . Chemicals in the Environment, Fiscal year 2002 , Tokyo : Environmental Health and Safety Division, Environmental Health Department, Ministry of the Environment Government of Japan . (in Japanese)
  • Yamamoto , S. , Kasai , T. , Matsumoto , M. , Nishizawa , T. , Arito , H. , Nagano , K. and Matsushima , T. 2002 . Carcinogenicity and chronic toxicity in rats and mice exposed to chloroform by inhalation . J. Occup. Health , 44 : 283 – 293 .
  • National Cancer Institute (NCI) . 1976 . Report on carcinogenesis bioassay of chloroform , Bethesda, MD : National Cancer Institute . NTIS PB-264-018
  • Jorgenson , T. A. , Meierhenry , E. F. , Rushbrook , C. J. , Bull , R. J. and Robinson , M. 1985 . Carcinogenicity of chloroform in drinking water to male Osborne–Mendel rats and female B6C3F1 mice . Fundam. Appl. Toxicol. , 5 : 760 – 769 .
  • Nagano , K. , Kano , H. , Arito , H. , Yamamoto , S. and Matsushima , T. 2006 . Enhancement of renal carcinogenicity by combined inhalation and oral exposures to chloroform in male rats . J. Toxicol. Environ. Health Pt. A , 69 : 1827 – 1842 .
  • United States Environmental Protection Agency (US EPA) . 2000 . Supplementary Guidance for Conducting Health Risk Assessment of Chemical Mixtures EPA 630/R–00/002
  • Withey , J. R. , Collins , B. T. and Collins , P. G. 1983 . Effect of vehicle on the pharmacokinetics and uptake of four halogenated hydrocarbons from the gastrointestinal tract of the rat . J. Appl. Toxicol. , 3 : 249 – 253 .
  • Morgan , D. L. , Cooper , S. W. , Carlock , D. L. , Sykora , J. J. , Sutton , B. , Mattie , D. R. and Mcdougal , J. N. 1991 . Dermal absorption of neat and aqueous volatile organic chemicals in the Fischer 344 rat . Environ. Res. , 55 : 51 – 63 .
  • Wang , P.-Y. , Kaneko , T. , Sato , A. , Charboneau , M. and Plaa , G. L. 1995 . Dose- and route-dependent alteration of metabolism and toxicity of chloroform in fed and fasting rats . Toxicol. Appl. Pharmacol. , 135 : 119 – 126 .
  • Islam , M. S. , Zhao , L. , Zhou , J. , Dong , L. , McDougal , J. N. and Flynn , G. L. 1999 . Systemic uptake and clearance of chloroform by hairless rats following dermal exposure: II. Absorption of the neat solvent . Am. Ind. Hyg. Assoc. J. , 60 : 438 – 443 .
  • Take , M. , Ohnishi , M. , Nagano , K. , Yamamoto , S. and Fukushima , S. 2009 . Design and performance of a system for blood collection of rats under whole-body inhalation exposure . J. Toxicol. Sci. , 34 : 221 – 226 .
  • Cohen , E. N. and Hood , N. 1969 . Application of low-temperature autoradiography to studies of the uptake and metabolism of volatile anesthetics in the mouse . I. chloroform. Anesthesiology , 30 : 306 – 314 .
  • Taylor , D. C. , Brown , D. M. , Keeble , R. and Langley , P. F. 1974 . Metabolism of chloroform- II. A sex difference in the metabolism of [14C]chloroform in mice . Xenobiotica , 4 : 165 – 174 .
  • Corley , R. A. , Mendrala , A. L. , Smith , F. A. , Staats , D. A. , Gargas , M. L. , Conolly , R. B. , Andersen , M. E. and Reitz , R. H. 1990 . Development of a physiologically based pharmacokinetic model for chloroform . Toxicol. Appl. Pharmacol. , 103 : 512 – 527 .
  • National Research Council . 1996 . Guide for the care and use of laboratory animals , Washington, DC : National Academy Press .
  • Rozman , K. K. and Klaassen , C. D. 2001 . “ Absorption, distribution, and excretion of toxicants ” . In Casarett & Doull's Toxicology, , Sixth Edition , 91 – 111 . New York : McGraw-Hill Companies, Inc. .
  • Enosawa , S. and Nakazawa , Y. 1986 . Changes in cytochrome P450 molecular species in rat liver in chloroform intoxication . Biochem. Pharmacol. , 35 : 1555 – 1560 .
  • Testai , E. and Vittozzi , L. 1986 . Biochemical alterations elicited in rat liver microsomes by oxidation and reduction products of chloroform metabolism . Chem. -Biol. Interact. , 59 : 157 – 171 .
  • Brady , J. F. , Li , D. , Ishizaki , H. , Lee , M. , Ning , S. M. , Xiao , F. and Yang , C. S. 1989 . Induction of cytochromes P450IIE1 and P450IIB1 by secondary ketones and the role of P450IIE1 in chloroform metabolism . Toxicol. Appl. Pharmacol. , 100 : 342 – 349 .
  • Fiserova–Bergerova , V. and Diaz , M. L. 1896 . Determination and prediction of tissue-gas partition coefficients . Int. Arch. Occup. Environ. Health , 58 : 75 – 87 .
  • Gargas , M. L. , Burgess , R. J. , Voisard , D. E. , Cason , G. H. and Andersen , M. E. 1989 . Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues . Toxicol. Appl. Pharmacol. , 98 : 87 – 99 .
  • Take , M. , Ohnishi , M. , Nagano , K. , Yamamoto , S. and Fukushima , S. Estimation of inhalation from oral gavage administration by blood chloroform and toluene concentration in rat . Proceedings of 16th Symposium on Environmental Chemistry, Kitakyushu . June 20–22 2007 , Fukuoka, Japan. pp. 698 – 699 . Ibaraki, Japan : Japan Society for Environmental Chemistry: Tsukuba . (in Japanese)

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.