Cytotoxic effects and oxidative stress response of six PBDE metabolites on human L02 cells

References

• Hites , R. A. 2004 . Polybrominated diphenyl ethers in the environment and in people: a meta- analysis of concentrations . Environ. Sci. Technol. , 38 : 945 – 956 .
   PubMed Web of Science ®Google Scholar
• Darnerud , P. O. , Eriksen , G. S. , Johannesson , T. , Larsen , P. B. and Viluksela , M. 2001 . Ploybrominated diphenyl ethers: occurrence, dietary exposure, and toxicology . Environ. Health Perspect. , 109 ( Suppl 1 ) : 49 – 68 .
   PubMed Web of Science ®Google Scholar
• Chen , D. A. , Mai , B. , Song , J. , Sun , Q. , Luo , Y. , Luo , X. , Zeng , E. Y. and Hale , R. C . 2007 . Polybrominated diphenyl ethers in birds of prey from Northern China . Environ. Sci. Technol. , 41 : 1828 – 1833 .
   PubMed Web of Science ®Google Scholar
• de Wit , C. A. 2002 . An overview of brominated flame retardants in the environment . Chemosphere , 46 : 583 – 624 .
   PubMed Web of Science ®Google Scholar
• Gill , U. , Chu , I. , Ryan , J. J. and Feeley , M. 2004 . Polybrominated diphenyl ethers: human tissue levels and toxicology . Rev. Environ. Contam. Toxicol. , 183 : 55 – 97 .
   PubMed Web of Science ®Google Scholar
• Hazrati , S. and Harrad , S. 2006 . Causes of variability in concentrations of polychlorinated biphenyls and polybrominated diphenyl ethers in indoor air . Environ. Sci. Technol. , 40 : 7584 – 7589 .
   PubMed Web of Science ®Google Scholar
• Law , R. J. , Allchin , C. R. , de Boer , J. , Covaci , A. , Herzke , D. , Lepom , P. , Morris , S. , Tronczynski , J. and de Wit , C. A. 2006 . Levels and trends of brominated flame retardants in the European environment . Chemosphere , 64 : 187 – 208 .
   PubMed Web of Science ®Google Scholar
• McDonald , T. A. 2005 . Polybrominated diphenylether levels among United States residents: daily intake and risk of harm to the developing brain and reproductive organs . Integr. Environ. Assess. Manag. , 1 : 343 – 354 .
   PubMed Web of Science ®Google Scholar
• Schecter , A. , Papke , O. , Harris , T. R. , Tung , K. C. , Musumba , A. , Olson , J. and Birnbaum , L. 2006a . Polybrominated diphenyl ether (PBDE) levels in expanded market basket survey of U.S. food and estimated PBDE dietary intake by age and sex . Environ. Health Perspect. , 114 : 1515 – 1520 .
   PubMed Web of Science ®Google Scholar
• Athanasiadou , M. , Cuadra , S. N. , Marsh , G. , Bergman , A. and Jakobsson , K. 2008 . Polybrominated diphenyl ethers (PBDEs) and bioaccumulative hydroxylated PBDE metabolites in young humans from Managua, Nicaragua . Environ. Health Perspect. , 116 : 400 – 408 .
   PubMed Web of Science ®Google Scholar
• Domingo , J. L. , Martí-Cid , R. , Castell , V. and Llobet , J. M. 2008 . Human exposure to PBDEs through the diet in Catalonia, Spain: temporal trend. A review of recent literature on dietary PBDE intake . Toxicology , 248 : 25 – 32 .
   PubMed Web of Science ®Google Scholar
• Furst , P. 2006 . Dioxins, polychlorinated biphenyls and other organohalogen compounds in human milk . Mol. Nutr. Food Res. , 50 : 922 – 933 .
   PubMed Web of Science ®Google Scholar
• Petreas , M. , She , J. , Brown , F. R. , Winkler , J. , Windham , G. , Rogers , E. , Zhao , G. , Bhatia , R. and Charles , M. J. 2003 . High body burdens of 2,2–,4,4–tetrabromodiphenyl ether (BDE-47) in California women . Environ. Health Perspect. , 111 : 1175 – 1179 .
   PubMed Web of Science ®Google Scholar
• Schecter , A. , Johnson-Welch , S. , Tung , K. C. , Harris , T. R. , Papke , O. and Rosen , R. 2007 . Polybrominated diphenyl ether (PBDE) levels in livers of U.S. human fetuses and newborns . J. Toxicol. Environ. Health Pt. A , 70 : 1 – 6 .
   PubMed Web of Science ®Google Scholar
• Schecter , A. , Papke , O. , Tung , K. C. , Joseph , J. , Harris , T. R. and Dahlgren , J. 2005a . Polybrominated diphenyl etherflameretardants in the US population: Current levels, temporal trends, and comparison with dioxins, dibenzofurans, and polychlorinated biphenyls . J. Occup. Environ. Med. , 47 : 199 – 211 .
   PubMed Web of Science ®Google Scholar
• Siddiqi , M. A. , Laessig , R. H. and Reed , K. D. 2003 . Polybrominated diphenyl ethers (PBDEs): new pollutants-old diseases . Clin. Med. Res. , 1 : 281 – 290 .
   PubMedGoogle Scholar
• Sjodin , A. , Patterson , D. G. Jr and Bergman , A. 2003 . A review on human exposure to brominated flame retardants—particularly polybrominated diphenyl ethers . Environ. Int. , 29 : 829 – 839 .
   PubMed Web of Science ®Google Scholar
• Eriksson , P. , Jakobsson , E. and Fredriksson , A. 2001 . Brominated flame retardants: a novel class of developmental neurotoxicants in our environment? . Environ. Health Perspect. , 109 : 903 – 908 .
   PubMed Web of Science ®Google Scholar
• Hallgren , S. , Sinjari , T. , Hakansson , H. and Darnerud , P. O. 2001 . Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice . Arch. Toxicol. , 75 : 200 – 208 .
   PubMed Web of Science ®Google Scholar
• Kuriyama , S. N. , Talsness , C. E. , Grote , K. and Chahoud , I. 2005 . Developmental exposure to low-dose PBDE-99: effects on male fertility and neurobehavior in rat offspring . Environ. Health Perspect. , 113 : 149 – 154 .
   PubMed Web of Science ®Google Scholar
• Lilienthal , H. , Hack , A. , Roth-Härer , A. , Grande , S. W. and Talsness , C. E. 2006 . Effects of developmental exposure to 2,2–,4,4–,5-pentabromodiphenyl ether (PBDE-99) on sex steroids, sexual development, and sexually dimorphic behavior in rats . Environ. Health Perspect. , 114 : 194 – 201 .
   PubMed Web of Science ®Google Scholar
• Marsh , G. , Stenutz , R. and Bergman , Å. 2003 . Synthesis of hydroxylated and methoxylated polybrominated diphenyl etherssNatural products and potential polybrominated diphenyl ether metabolites . Eur. J. Org. Chem. , 14 : 2566 – 2576 .
   Google Scholar
• Reistad , T. , Fonnum , F. and Mariussen , E. 2006 . Neurotoxicity of the pentabrominated diphenyl ether mixture, DE-71, and hexabromocyclododecane (HBCD) in rat cerebellar granule cells in vitro . Arch. Toxicol. , 80 : 785 – 796 .
   PubMed Web of Science ®Google Scholar
• Madia , F. , Giordano , G. , Fattori , V. , Vitalone , A. , Branchi , I. , Capone , F. and Costa , L. G. 2004 . Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells . Toxicol. Lett. , 154 : 11 – 21 .
   PubMed Web of Science ®Google Scholar
• Hakk , H. and Letcher , R. J. 2003 . Metabolism in the toxicokinetics and fate of brominated flame retardants—A review . Environ. Int. , 29 : 801 – 828 .
   PubMed Web of Science ®Google Scholar
• Hovander , L. , Malmberg , T. , Athanasiadou , M. , Athanassiadis , I. , Rahm , S. , Bergman , Å. and Wehler , E. K. 2002 . Identification of hydroxylated PCB metabolites and other phenolic halogenated pollutants in human blood plasma . Arch. Environ. Contam. Toxicol. , 42 : 105 – 117 .
   PubMed Web of Science ®Google Scholar
• Marsh , G. , Athanasiadou , M. , Athanassiadis , I. and Sandholm , A. 2006 . Identification of hydroxylated metabolites in 2,2–,4,4—tetratbromodiphenyl ether exposed rats . Chemosphere , 63 : 690 – 697 .
   PubMed Web of Science ®Google Scholar
• Marsh , G. , Athanasiadou , M. , Bergman , A. and Asplind , L. 2004 . Identification of hydroxylated and methoxylated polybrominated diphenyl ethers in Baltic Sea salmon (Salmo salar) blood . Environ. Sci. Technol. , 38 : 10 – 18 .
   PubMed Web of Science ®Google Scholar
• McKinney , M. A. , De Guise , S. , Martineau , D. , Beland , P. , Arukwe , A. and Letcher , R. J. 2006 . Biotransformation of polybrominated diphenyl ethers and polychlorinated biphenyls in beluga whale (Delphinapterus leucas) and rat mammalian model using an in vitro hepatic microsomal assay . Aquat. Toxicol. , 77 : 87 – 97 .
   PubMed Web of Science ®Google Scholar
• Sinkkonen , S. , Rantalainen , A. L. , Paasivirta , J. and Lahtipera , M. 2004 . Polybrominated methoxy diphenyl ethers (MeO-PBDEs) in fish and guillemots of Baltic Atlantic and Arctic environments . Chemosphere , 56 : 767 – 775 .
   PubMed Web of Science ®Google Scholar
• Teuten , E. L. , Xu , L. and Reddy , C. M. 2005 . Two abundant bioaccumulated halogenated compounds are natural products . Science , 307 : 917 – 920 .
   PubMed Web of Science ®Google Scholar
• Valters , K. , Li , H. , Alaee , M. , D’Sa , I. , Marsh , G. , Bergman , A. and Letcher , R. J. 2005 . Polybrominated diphenyl ethers and hydroxylated and methoxylated brominated and chlorinated analogues in the plasma of fish from the Detroit River . Environ. Sci. Technol. , 39 : 5612 – 5619 .
   PubMed Web of Science ®Google Scholar
• Letcher , R. J. , Klasson-Wehler , E. and Bergman , A. 2000 . Methyl sulfate and hydroxylated metabolites of polychlorinated biphenyls . The Handbook Environ. Chem. , 3 part K.
   Google Scholar
• Örn , U. and Klasson-Wehler , E. 1998 . Metabolism of 2,20,4,40-tetrabromodiphenyl ether in rat and mouse . Xenobiotica. , 28 : 199 – 211 .
   PubMed Web of Science ®Google Scholar
• Hamers , T. , Kamstra , J. H. , Sonneveld , E. , Murk , A. J. , Keter , M. H.A. , Andersson , P. L. , Legler , J. and Brouwer , A. 2006 . In vitro profiling of the endocrine-disrupting potency of brominated flame retardants . Toxicol Sci , 92 : 157 – 173 .
   PubMed Web of Science ®Google Scholar
• Canton , R. F. , Sanderson , J. T. , Nijmeijer , S. , Bergman , A. , Letcher , R. J. and van den Berg , M. 2006 . In vitro effects of brominated flame retardants and metabolites on CYP17 catalytic activity: a novel mechanism of action? . Toxicol. Appl. Pharmacol. , 216 : 274 – 281 .
   PubMed Web of Science ®Google Scholar
• Canton , R. F. , Sanderson , T. , Letcher , R. J. , Bergman , A. and van den Berg , M. 2005 . Inhibition and induction of aromatase (CYP19) activity by brominated flame retardants in H295R human adrenocortical carcinoma cells . Toxicol. Sci. , 88 : 447 – 455 .
   PubMed Web of Science ®Google Scholar
• Song , R. , He , Y. , Murphy , M. B. , Yeung , L. W. , Yu , R. M. , Lam , M. H. , Lam , P. K. , Hecker , M. , Giesy , J. P. , Wu , R. S. , Zhang , W. , Sheng , G. and Fu , J . 2008 . Effects of fifteen PBDE metabolites, DE71, DE79 and TBBPA on steroidogenesis in the H295R cell line . Chemosphere , 71 : 1888 – 1894 .
   PubMed Web of Science ®Google Scholar
• Meerts , I. A.T.M. , van Zanden , J. J. , Luijkis , E. A.C. , van Leeuwen-Bol , I. , Marsh , G. , Jakobsson , E. , Bergman , A. and Brouwer , A. 2000 . Potent competitive interactions of some polybrominated flame retardants and related compounds with human transthyretin in vitro . Toxicol. Sci. , 56 : 95 – 104 .
   PubMed Web of Science ®Google Scholar
• Masella , R. , Di Benedetto , R. , Vari , R. , Filesi , C. and Giovannini , C. 2005 . Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes . J. Nutr. Biochem. , 16 : 577 – 586 .
   PubMed Web of Science ®Google Scholar
• He , P. , He , W. , Wang , A. , Xia , T. , Xu , B. , Zhang , M. and Chen , X. 2008 . PBDE47-induced oxidative stress, DNA damage and apoptosis in primary cultured rat hippocampal neurons . Neurotoxicology , 29 : 124 – 129 .
   PubMed Web of Science ®Google Scholar
• Shao , J. , White , C. C. , Dabrowski , M. J. , Kavanagh , T. J. , Eckert , M. L. and Gallagher , E. P. 2008 . The role of mitochondrial and oxidative injury in BDE 47 toxicity to human fetal liver hematopoietic stem cells . Toxicol. Sci. , 101 : 81 – 90 .
   PubMed Web of Science ®Google Scholar
• An , J. , Li , S. H. , Zhong , Y. F. , Wang , Y. P. , Zhen , K. W. , Zhang , X. Y. , Wang , Y. J. , Wu , M. H. , Yu , Z. Q. , Sheng , G. Y. , Fu , J. M. and Huang , Y. C. 2010 . The cytotoxic effects of synthetic 6-hydroxylated and 6-methoxylated polybrominated diphenyl ether 47 (BDE47) . Environ. Toxicol. , Apr 12. [Epub ahead of print]
   PubMed Web of Science ®Google Scholar
• Wang , J. , Zhang , J. , Bai , S. , Wang , G. , Mu , L. , Sun , B. , Wang , D. , Kong , Q. , Liu , Y. , Yao , X. , Xu , Y. and Li , H . 2009 . Simulated microgravity promotes cellular senescence via oxidant stress in rat PC12 cells . Neurochem. Int. , 55 ( 7 ) : 710 – 716 .
   PubMed Web of Science ®Google Scholar