Publication Cover
Journal of Environmental Science and Health, Part A
Toxic/Hazardous Substances and Environmental Engineering
Volume 48, 2013 - Issue 14
351
Views
28
CrossRef citations to date
0
Altmetric
ARTICLES

Hygroscopic aerosol deposition in the human upper respiratory tract under various thermo-humidity conditions

, , &
Pages 1790-1805 | Received 02 Apr 2013, Published online: 05 Sep 2013

References

  • International Commission on Radiological Protection (ICRP) . Human Respiratory Tract Model for Radiological Protection , New York : Elsevier Science Ltd . 1994
  • Ferron , G. A. 1977 . The size of soluable aerosol particles as a function of the humidity of the air: Application to the human respiratory tract . J. Aerosol Sci , 3 : 251 – 267 .
  • Ferron , G. A. , Kreyling , W. G. and Haider , B. 1988 . Inhalation of salt aerosol particles - II. Growth and deposition in the human respiratory tract . J. Aerosol Sci , 19 : 611 – 631 .
  • Finlay , W. H. and Stapleton , K. W. 1995 . The effect on regional lung deposition of coupled heat and mass-transfer between hygroscopic droplets and their surrounding phase . J. Aerosol Sci , 26 : 655 – 670 .
  • Li , W. and Hopke , P. K. 1993 . Initial size distributions and hygroscopicity of indoor combustion aerosol particles . Aerosol Sci. Technol , 19 : 305 – 316 .
  • Martonen , T. B. , Bell , K. A. , Phalen , R. F. , Wilson , A. F. and Ho , A. 1982 . “ Growth rate measurements and deposition modeling of hygroscopic aerosols in human tracheobronchial models ” . In Inhaled Particles V , Edited by: Walton , W. H. 93 – 107 . Oxford , , UK : Pergamon Press .
  • Zhang , Z. , Kleinstreuer , C. and Kim , C. S. 2006 . Water vapor transport and its effects on the deposition of hygroscopic droplets in a human upper airway model . Aerosol Sci. Technol , 40 : 52 – 67 .
  • Cinkotai , F. F. 1971 . The behavior of sodium chloride particles in moist air . J. Aerosol Sci , 2 : 325 – 329 .
  • Peng , C. , Chow , A. H.L. and Chan , C. K. 2000 . Study of the hygroscopic properties of selected pharmaceutical aerosols using single particle levitation . Pharm. Res , 17 : 1104 – 1109 .
  • Ferron , G. A. , Oberdorster , G. and Hennenberg , R. 1989 . Estimation of the deposition of aerosolised drugs in the human respiratory tract due to hygroscopic growth . J. Aerosol Med , 2 : 271
  • Robinson , R. and Yu , C. P. 1998 . Theoretical analysis of hygroscopic growth rate of mainstream and sidestream cigarette smoke particles in the human respiratory tract . Aerosol Sci. Technol , 28 : 21 – 32 .
  • Zhang , Z. , Kleinstreuer , C. and Kim , C. S. 2006 . Isotonic and hypertonic saline droplet deposition in a human upper airway model . J. Aerosol Med , 19 : 184 – 198 .
  • Longest , P. W. and Xi , J. 2008 . Condensational growth may contribute to the enhanced deposition of cigarette smoke particles in the upper respiratory tract . Aerosol Sci. Technol , 42 : 579 – 602 .
  • Kim , J. W. , Xi , J. and Si , X. 2013 . Dynamic growth and deposition of hygroscopic aerosols in the nasal airway of a 5-year-old child . Int. J. Numer. Meth. Biomed. Eng , 29 : 17 – 39 .
  • Ferron , G. A. , Haider , B. and Kreyling , W. G. 1984 . Conditions for measuring supersaturation in the human lung using aerosols . J. Aerosol Sci , 15 : 211 – 215 .
  • Longest , P. W. and Hindle , M. 2011 . Numerical model to characterize the size Increase of combination drug and hygroscopic excipient nanoparticle aerosols . Aerosol Sci. Technol , 45 : 884 – 899 .
  • Longest , P. W. , Tian , G. and Hindle , M. 2011 . Improving the lung delivery of nasally administered aerosols during noninvasive ventilation-an application of enhanced condensational growth (ECG) . J. Aerosol Med. Pulm. D , 24 : 103 – 118 .
  • Tian , G. , Longest , P. W. , Su , G. G. and Hindle , M. 2011 . Characterization of respiratory drug delivery with enhanced condensational growth using an individual path model of the entire tracheobronchial airways . Ann. Biomed. Eng , 39 : 1136 – 1153 .
  • Xi , J. and Longest , P. W. 2009 . Characterization of submicrometer aerosol deposition in extrathoracic airways during nasal exhalation . Aerosol Sci. Technol , 43 : 808 – 827 .
  • Zhou , Y. , Xi , J. , Simpson , J. , Irshad , H. and Cheng , Y. S. 2013 . Aerosol deposition in a nasopharyngolaryngeal replica of a 5-year-old child . Aerosol Sci. Technol , 47 : 275 – 282 .
  • Xi , J. and Longest , P. W. 2007 . Transport and deposition of micro-aerosols in realistic and simplified models of the oral airway . Ann. Biomed. Eng , 35 : 560 – 581 .
  • Xi , J. and Longest , P. W. 2008 . Evaluation of a drift flux model for simulating submicrometer aerosol dynamics in human upper tracheobronchial airways . Ann. Biomed. Eng , 36 : 1714 – 1734 .
  • Wilcox , D. C. Turbulence Modeling for CFD, 2nd , La Cañada Flintridge, CA : DCW Industries, Inc. . 1998
  • Bird , R. B. , Steward , W. E. and Lightfoot , E. N. 1960 . Transport Phenomena , New York : John Wiley & Sons .
  • Green , D. W. 1997 . Perry's Chemical Engineers’ Handbook, 7th Ed. , New York : McGraw-Hill .
  • Morsi , S. A. and Alexander , A. J. 1972 . An investigation of particle trajectories in two-phase flow systems . J. Fluid Mech , 55 : 193 – 208 .
  • Allen , M. D. and Raabe , O. G. 1985 . Slip correction measurements of spherical solid aerosol particles in an improved Millikan apparatus . Aerosol Sci. Technol , 4 : 269 – 286 .
  • Matida , E. A. , Finlay , W. H. and Grgic , L. B. 2004 . Improved numerical simulation of aerosol deposition in an idealized mouth-throat . J. Aerosol Sci , 35 : 1 – 19 .
  • Longest , P. W. and Xi , J. 2007 . Effectiveness of direct Lagrangian tracking models for simulating nanoparticle deposition in the upper airways . Aerosol Sci. Technol , 41 : 380 – 397 .
  • Hinds , W. C. 1999 . Aerosol Technology: Properties, Behavior, and Measurement of Airborne Particles , New York : John Wiley and Sons .
  • Longest , P. W. and Kleinstreuer , C. 2005 . Computational models for simulating multicomponent aerosol evaporation in the upper respiratory airways . Aerosol Sci. Technol , 39 : 124 – 138 .
  • Atkins , P. and de Paula , J. 2006 . Physical Chemistry, 8th Ed. , 146 Oxford , , UK : Oxford University Press .
  • Xi , J. and Longest , P. W. 2008 . Effects of oral airway geometry characteristics on the diffusional deposition of inhaled nanoparticles . J. Biomech. Eng , 130 : 16
  • Xi , J. and Longest , P. W. 2008 . Numerical predictions of submicrometer aerosol deposition in the nasal cavity using a novel drift flux approach . Int. J. Heat Mass Tran , 51 : 5562 – 5577 .
  • Wexler , D. B. and Davidson , T. M. 2004 . The nasal valve: A review of the anatomy, imaging, and physiology . Am. J. Rhinol , 18 : 143 – 150 .
  • Cheng , K. H. , Cheng , Y. S. , Yeh , H. C. and Swift , D. L. 1995 . Deposition of Ultrafine Aerosols in the Head Airways During Natural Breathing and During Simulated Breath Holding Using Replicate Human Upper Airway Casts . Aerosol Sci. Technol , 23 : 465 – 474 .
  • Cheng , Y. S. , Su , Y. F. , Yeh , H. C. and Swift , D. L. 1993 . Deposition of Thoron progeny in human head airways . Aerosol Sci. Technol , 18 : 359 – 375 .
  • Cheng , Y. S. 2003 . Aerosol deposition in the extrathoracic region . Aerosol Sci. Technol , 37 : 659 – 671 .
  • Garcia , G. J.M. , Tewksbury , E. W. , Wong , B. A. and Kimbell , J. S. 2009 . Interindividual Variability in Nasal Filtration as a Function of Nasal Cavity Geometry . J. Aerosol Med. Pulm. D , 22 : 139 – 155 .
  • Guilmette , R. A. , Wicks , J. D. and Wolff , R. K. 1989 . Morphometry of human nasal airways in vivo using Magnetic Resonance Imaging . J. Aerosol Med , 2 : 365 – 377 .
  • Zheng , L. , Wang , Y. X. , Plawsky , J. L. and Wayner , P. C. 2002 . Effect of curvature, contact angle, and interfacial subcooling on contact line spreading in a microdrop in dropwise condensation . Langmuir , 18 : 5170 – 5177 .
  • Gill , P. E. and Murray , W. 1978 . Algorithms for the solution of the nonlinear least-squares problem . SIAM J. Numer. Anal , 15 : 977 – 992 .
  • Martonen , T. B. 1992 . Deposition patterns of cigarette smoke in human airways . Am. Ind. Hyg. Assoc. J. , 53 : 6 – 18 .
  • Phalen , R. F. , Oldham , M. J. and Mannix , R. C. 1994 . Cigarette smoke deposition in the tracheobronchial tree: Evidence for colligative effects . Aerosol Sci. Technol , 20 : 215 – 226 .
  • Pritchard , J. N. and Black , A. 1984 . “ An estimation of the tar particulate material depositing in the respiratory tracts of healthy male middle- and low-tar cigarette smokers ” . In Aerosols , Edited by: Liu , B. Y.H. , Pui , D. Y.H. and Fissan , H. J. 989 – 992 . New York : Elsevier Science .
  • Schlesinger , R. B. , Gurman , J. L. and Lippmann , M. 1982 . Particle deposition within bronchial airways: Comparisons using constant and cyclic inspiratory flows . Ann. Occup. Hyg , 26 : 47 – 64 .
  • Ingebrethsen , B. J. 1989 . “ The physical properties of mainstream cigarette smoke and their relationship to deposition in the respiratory tract ” . In Extrapolation of Dosimetric Relationships for Inhaled Particles and Gases , Edited by: Crapo , J. D. , Smolko , E. D. , Miller , F. J. , Graham , J. A. and Hayes , A. W. San Diego , CA : Academic Press .
  • Doorly , D. J. , Taylor , D. J. , Gambaruto , A. M. , Schroter , R. C. and Tolley , N. 2008 . Nasal architecture: form and flow . Philos. T. Roy. Soc. A , 366 : 3225 – 3246 .
  • Rouadi , P. , Baroody , F. M. , Abbott , D. , Naureckas , E. , Solway , J. and Naclerio , R. M. 1999 . A technique to measure the ability of the human nose to warm and humidify air . J. Appl. Physiol , 87 : 400 – 406 .
  • Shi , H. , Kleinstreuer , C. and Zhang , Z. 2006 . Laminar airflow and nanoparticle or vapor deposition in a human nasal cavity model . J. Biomech. Eng , 128 : 697 – 706 .
  • Keyhani , K. , Scherer , P. W. and Mozell , M. M. 1995 . Numerical simulation of airflow in the human nasal cavity . J. Biomech. Eng , 117 : 429 – 441 .
  • Robinson , R. J. and Yu , C. P. 2001 . Deposition of cigarette smoke particles in the human respiratory tract . Aerosol Sci. Technol , 34 : 202 – 215 .
  • Subramaniam , R. P. , Richardson , R. B. , Morgan , K. T. , Kimbell , J. S. and Guilmette , R. A. 1998 . Computational fluid dynamics simulations of inspiratory airflow in the human nose and nasopharynx . Inhal. Toxicol , 10 : 91 – 120 .
  • Fodil , R. , Brugel-Ribere , L. , Croce , C. l. , Sbirlea-Apiou , G. , Larger , C. , Papon , J. F.o. , Delclaux , C. , Coste , A. , Isabey , D. and Louis , B. 2005 . Inspiratory flow in the nose: a model coupling flow and vasoerectile tissue distensibility . J. Appl. Physiol , 98 : 288 – 295 .
  • Finlay , W. H. 1998 . Estimating the type of hygroscopic behavior exhibited by aqueous droplets . J. Aerosol Med , 11 : 221 – 229 .
  • Hilberg , O. , Jensen , F. T. and Pedersen , O. F. 1993 . Nasal airway geometry: comparison between acoustic reflections and magnetic resonance scanning . J. Appl. Physiol , 75 : 2811 – 2819 .
  • Pickering , D. N. and Beardsmore , C. S. 1999 . Nasal flow limitation in children . Pediatr. Pulmonol , 27 : 32 – 36 .
  • Mirza , N. , Kroger , H. and Doty , R. L. 1997 . Influence of age on the ‘nasal cycle’ . Laryngoscope , 107 : 62 – 66 .
  • Ohki , M. , Ogoshi , T. , Yuasa , T. , Kawano , K. and Kawano , M. 2005 . Extended observation of the nasal cycle using a portable rhinoflowmeter . J. Otolaryngol , 34 : 346 – 349 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.