Antioxidative and xanthine oxidase inhibitory activities and phytochemical screening of the hydro-alcoholic extract of mace, aril of Myristica fragrans: Implication as an adjuvant therapy in gout

References

• WHO. 2013. WHO Traditional Medicine Strategy, 2014–2023; WHO Press: Geneva, Switzerland.
   Google Scholar
• Ghosh, D.; Bagchi, D.; Konishi, T. Clinical Aspects of Functional Foods and Nutraceuticals: CRC Press/Taylor & Francis: Florida, USA, 2014; 1–445.
   Google Scholar
• Nagano, I. Myristicafragrans: An Exploration of the Spice. The Entheogen Review 2008, 16, 15–24.
   Google Scholar
• Akinboro, A.; Mohammad, A.B.; Asmawi, M.Z.; Sulaiman, S.F.; Sofiman, O.A. Antioxidants in Aqueous Extract of Myristicafragrans (Houtt.) Suppress Mitosis and Cyclophosphamide-Induced Chromosomal Aberrations in Allium Cepa L. Cells. Journal of Zhejiang University–ScienceB 2011, 12, 915–922.
   Google Scholar
• Somani, R.; Karve, S.; Jain, D.; Jain, K.; Singhai, A.K. Phytochemical and Pharmacological Potential of Myristicafragranshoutt: A Comprehensive Review. Pharmacognosy Reviews 2008, 2, 68–76.
   Google Scholar
• Kuo, C.F.; Grainge, M.J.; Zhang, W.; Doherty, M. Global Epidemiology of Gout: Prevalence, Incidence and Risk Factors. Nature Review Rheumatology 2015, 11, 649–662.
   PubMed Web of Science ®Google Scholar
• Nuki, G. An appraisal of the 2012 American College of Rheumatology Guidelines for the Management of Gout. Current Opinion in Rheumatology 2014, 26, 152–161.
   PubMed Web of Science ®Google Scholar
• Arellano, F.; Sacristan, J.A. Allopurinol Hypersensitivity Syndrome: A Review. Annals of Pharmacotherapy 1993, 27, 337–343.
   PubMed Web of Science ®Google Scholar
• Gomes, E.R.; Demoly, P. Epidemiology of Hypersensitivity Drug Reactions. Current Opinion in Allergy & Clinical Immunology 2005, 5, 309–316.
   PubMed Web of Science ®Google Scholar
• Christine, M.K.; Milner, J.A. Herbs and Spices in Cancer Prevention and Treatment. In Herbal Medicine: Biomolecular and Clinical Aspects; Benzei, I.F.F.; Wachtel-Galor, S.; Eds.; 2nd Ed., CRC Press: Boca Raton, FL, 2011.
   Google Scholar
• Sloan, A.E. Top 10 Global Food Trends. Food Technology 2005, 59, 20–32.
   Web of Science ®Google Scholar
• Ullah, M.F.; Bhat, S.H.; Hussain, E.; Abu-Duhier, F.; Hadi, S.M.; Ahmad, A.; Sarkar, F.H. Cancer Chemopreventive Pharmacology of Phytochemicals Derived from Plants of Dietary and Non-Dietary Origin: Implication for Alternative and Complementary Approaches. Phytochemistry Reviews 2014, 13, 811–833.
   Web of Science ®Google Scholar
• Suarez, B.; Alvarez, A.I.; Garcia, D.; Barrio, G.D.; Lobo, A.P.; Parra, F. Phenolic Profiles, Antioxidant Activity and in Vitro Antiviral Properties of Apple Pomace. Food Chemistry 2010, 120, 339–342.
   Google Scholar
• Blainski, A.; Lopes, G.C.; Palazzo De Mello, J.C. Application and Analysis of the Folin–Ciocalteu Method for the Determination of the Total Phenolic Content from Limoniumbrasiliense L. Molecules 2013, 18, 6852–6865.
   PubMed Web of Science ®Google Scholar
• Makkar, H.P.S. Quantification of Tannins in Tree Foliage: A Laboratory Manual, FAO/IAEA Working Document, Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, Vienna, Austria, 2000.
   Google Scholar
• Harborne, J.B. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis; Chapman and Hall: London, UK, 1976; 99–100, 109–110, 144–147, 185–188.
   Google Scholar
• Miliauskas, G.; Venskutonis, P.R.; Van Beck, T.A. Screening of Radical Scavenging of Some Medicinal and Aromatic Plant Extracts. Food Chemistry 2004, 85, 231–237.
   Web of Science ®Google Scholar
• Re, R.; Pellegrini, N.; Proteggente, A.; Pannala, A.; Yang, M.; Rice-Evans, C. Antioxidant Activity Applying an Improved ABTS Radical Cation Decolorization Assay. Free Radical Biology and Medicine 1999, 26, 1231–1237.
   PubMed Web of Science ®Google Scholar
• Vani, T.; Rajani, M.; Sarkar, S.; Shishoo, C.J. Antioxidant Properties of the Ayurvedic Formulation—Antioxidant Properties of the Ayurvedic Formulation—Triphala and Its Constituents. International Journal of Pharmaceutics 1997, 5, 303–317.
   Google Scholar
• Hazra, B.; Biswas, S.; Mandal, N. Antioxidant and Free Radical Scavenging Activity of Spondiaspinnata. BMC Complementary and Alternative Medicine 2008, 8, 63.
   PubMed Web of Science ®Google Scholar
• Mukherjee, S.; Pawar, N.; Kulkarni, O.; Nagarkar, B.; Thopte, S.; Bhujbal, A.; Pawar, P. Evaluation of Free-Radical Quenching Properties of Standard Ayurvedic Formulation Vayasthapana Rasayana. BMC Complementary and Alternative Medicine 2011, 11, 38.
   PubMed Web of Science ®Google Scholar
• Owen, P.L.; Johns, T. Xanthine Oxidase Inhibitory Activity of Northeastern North American Plant Remedies Used for Gout. Journal of Ethnophamacology 1999, 64, 149–160.
   PubMed Web of Science ®Google Scholar
• Abdullahi, A.; Hamzah, R.U.; Jigam, A.A.; Kabiru, A.Y.; Muhammad, H.; Sakpe, S.; Adefolalu, F.S.; Isah, M.C.; Kolo, M.Z. Inhibitory Activity of Xanthine Oxidase by Fractions of Cratevaadansonii. Journal of Acute Disease 2012, 1, 126–129.
   Google Scholar
• Ramawat, K.G.; Dass, S.; Mathur, M. The Chemical Diversity of Bioactive Molecules and Therapeutic Potential of Medicinal Plants. In Herbal Drugs: Ethnomedicine to Modern Medicine; Ramawat, K.G.; Ed.; Springer-Verlag: Berlin, Heidelberg, Germany, 2009; 7–32.
   Google Scholar
• Ullah, M.F.; Bhat, S.H.; Hussain, E., Abu-Duhier, F.; Hadi, S.M.; Ahmad, A.; Sarkar, F.H. Pharmacological Intervention Through Dietary Nutraceuticals in Gastrointestinal Neoplasia. Critical Reviews in Food Science & Nutrition 2016, 56, 1501–1518.
   Google Scholar
• Ullah, M.F. Sulforaphane (SFN): An Isothiocyanate in a Cancer Chemoprevention Paradigm. Medicines 2015, 2, 141–156.
   Google Scholar
• Xu, F.; Zhao, X.; Yang, L.; Wang, X.; Zhao, J. A New Cycloartane-Type Triterpenoidsaponin Xanthine Oxidase Inhibitor from Homonoiariparia Lour. Molecules 2014, 19, 13422–13431.
   PubMed Web of Science ®Google Scholar
• Wu, X.H.; Ruan, J.L.; Zhang, J.; Wang, S.Q.; Zhang, Y.W. Pallidifloside D, a Saponin Glycoside Constituent from Smilax Riparia, Resist to Hyperuricemia Based on URAT1 and GLUT9 in Hyperuricemic Mice. Journal of Ethnopharmacology 2014, 18, 201–205.
   Web of Science ®Google Scholar
• Kong, L.; Cai, Y.; Huang, W.; Cheng, C.H.; Tan, R. Inhibition of Xanthine Oxidase by Some Chinese Medicinal Plants Used to Treat Gout. Journal of Ethnopharmacology 2000, 73, 199–207.
   PubMed Web of Science ®Google Scholar
• Bochu, W.; Ling, X. A Review of Phytotherapy of Gout: Perspective of New Pharmacological Treatments. Pharmazie 2014, 69, 243–256.
   PubMed Web of Science ®Google Scholar
• Griffith, B.; Pendyala, S.; Hecker, L.; Lee, P.J.; Natarajan, V.; Thannickal, V.J. NOX Enzymes and Pulmonary Disease. Antioxidants and Redox Signaling 2009, 11, 2505–2516.
   PubMed Web of Science ®Google Scholar
• Wu, J.; Fernandes-Alnemri, T.; Alnemri, E.S. Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeriamonocyto Genes. Journal of Clinical Immunology 2010, 30, 693–702.
   PubMed Web of Science ®Google Scholar
• Harijith, A.; Ebenezer, D.L.; Natarajan, V. Reactive Oxygen Species at the Cross Roads of Inflammasome and Inflammation. Frontiers in Physiology 2014, 5(352), 1–11.
   PubMed Web of Science ®Google Scholar
• Bhaumik, U.K.; Kumar, A.D.; Selvan, V.T.; Saha, P.; Gupta, M.; Mazumder, U.K. Antioxidant and Free Radical Scavenging Property of Methanol Extract of Blumealanceolaria Leaf in Different in Vitro Models. Pharmacology Online 2008, 2, 74–89.
   Google Scholar
• Zheng, W.; Wang, S.Y. Antioxidant Activity and Phenolic Compounds in Selected Herbs. Journal of Agriculture and Food Chemistry 2001, 49, 5165–5170.
   PubMed Web of Science ®Google Scholar
• Adedapo, A.A.; Jimoh, F.O.; Afolayan, A.J.; Masika, P.J. Antioxidant Activities and Phenolic Contents of the Methanol Extracts of the Stems of Acokantheraoppositifolia and Adeniagummifera. BMC Complementary and Alternative Medicine 2008, 8, 54–60.
   PubMed Web of Science ®Google Scholar
• George, J.; Carr, E.; Davies, J.; Belch, J.J.H.; Struthers, A. High-Dose Allopurinol Improves Endothelial Function by Profoundly Reducing Vascular Oxidative Stress and Not by Lowering Uric Acid. Circulation 2006, 114, 2508–2516.
   PubMed Web of Science ®Google Scholar
• Biemond, P.; Swaak, A.J.G.; Van Eijk, H.G.; Koster, J.F. Intra-Articular Ferritin-Bound Iron in Rheumatoid Arthritis: A Factor That Increases Oxygen Free Radical-Induced Tissue Destruction. Arthritis & Rheumatism 2005, 29, 1187–1193.
   Web of Science ®Google Scholar
• Borges, F.; Feranandes, E.; Roleira, F. Progress Towards the Discovery of Xanthine Oxidase Inhibitors. Current Medicinal Chemistry 2002, 9, 195–217.
   PubMed Web of Science ®Google Scholar
• Burke, A.; Smyth, E.; FitzGerald, G.A. Analgesic-Antipyretic Agents: Pharmacotherapy of Gout. In Goodman & Gilman’s the Pharmacological Basis of Therapeutics; Brunton, L.L; Lazo, J.S; Parker, K.L; Eds.; McGraw-Hill Medical Publishing Division: New York, NY, 2006; 706–710.
   Google Scholar
• Ullah, M.F.; Bhat, S.H.; Abu-Duhier, F. Anti-Diabetic Potential of Hydro-Alcoholic Extract of Moringaperegrina Leaves: Implication as Functional Food for Prophylactic Intervention in Prediabetic Stage. Journal of Food Biochemistry 2015, 39, 349–490.
   Google Scholar
• Opara, E.I.; Chohan, M. Culinary Herbs and Spices: Their Bioactive Properties, the Contribution of Polyphenols and the Challenges in Deducing Their True Health Benefits. International Journal of Molecular Sciences 2014, 15, 19183–19202.
   PubMed Web of Science ®Google Scholar
• Younsi, F.; Trimech, R.; Boulila, A.; Ezzine, O.; Dhahri, S.; Boussaid, M.; Messaoud, C. Essential Oil and Phenolic Compounds of Artemisia Herba-Alba (Asso.): Composition, Antioxidant, Antiacetylcholinesterase, and Antibacterial Activities. International Journal of Food Properties 2016, 19, 1425–1438.
   Google Scholar
• Szabo, M.R.; Radu, D.; Gavrilas, S.; Chambre, D.; Iditoiu, C. Antioxidant and Antimicrobial Properties of Selected Spice Extracts. International Journal of Food Properties 2010, 13, 535–545.
   Web of Science ®Google Scholar