3,577
Views
5
CrossRef citations to date
0
Altmetric
Reviews

Mechanisms involved in the cardioprotective effect of avocado consumption: A systematic review

, , , &

References

  • Escosteguy, C.C.; Portela, M.C.; Lima, S.M.L.; Ferreira, V.M.B.; De, V.M.T.L.; UtilizaçÃo, B.C. De Diretrizes Clínicas Em Cardiologia Na Saúde Suplementar No Brasil. Revista Da Associação Médica Brasileira 2008, 54(5), 400–405.
  • Berthiaume, J.M.; Azam, S.M.; Hoit, B.D.; Chandler, M.P. Cardioprotective Effects of Dietary Lipids Evident in the Time-dependent Alterations of Cardiac Function and Gene Expression following Myocardial Infarction. Physiological Reports 2014 May 20, 2(5), e12019–e12019.
  • Colette, C.; Percheron, C.; Pares-Herbute, N.; Michel, F.; Pham, T.-C.; Brillant, L.; et al. Exchanging Carbohydrates for Monounsaturated Fats in Energy-Restricted Diets: Effects on Metabolic Profile and Other Cardiovascular Risk Factors. International Journal of Obesity and Related Metabolic Disorders: Journal of the International Association for the Study of Obesity 2003, 27(6), 648–656.
  • Wang, L.; Bordi, P.L.; Fleming, J.A.; Hill, A.M.; Kris-Etherton, P.M. Effect of a Moderate Fat Diet with and without Avocados on Lipoprotein Particle Number, Size and Subclasses in Overweight and Obese Adults: A Randomized, Controlled Trial. Journal of the American Heart Association 2015, 4(1), e001355–e001355.
  • Xavier, H.; Izar, M.; Farias Neto, J.; Assad, M.; Rocha, V.; Sposito, A.; et al.V Diretriz Brasileira de Dislipidemias e Prevenção da Aterosclerose. Arquivos Brasileiros De Cardiologia. 2013, 101(4), 120–129.
  • Montera, M.; Mesquita, E.; Colafranceschi, A.; Oliveira Junior, A.; Rabischoffsky, A.; Ianni, B.; et al. I Diretriz Brasileira De Miocardites E Pericardites. Arquivos Brasileiros de Cardiologia, 2013, 100(4), 1–36.
  • Hirasawa, M.; Shimura, K.; Shimizu, A.; Mura, K.; Tokue, C.; Arai, S. Quantification and Functional Analysis of Dietary Fiber and Polyphenols in Avocado. Journal of the Japanese Society for Food Science and Technology-Nippon Shokuhin Kagaku Kogaku Kaishi 2008, 55(3), 95–101.
  • Gillingham, L.G.; Harris-Janz, S.; Jones, P.J.H. Dietary Monounsaturated Fatty Acids are Protective against Metabolic Syndrome and Cardiovascular Disease Risk Factors. Lipids 2011 Mar 10, 46(3), 209–228.
  • Madrigal, J.C.; Muñoz, M.A.; Herrera Abarca, J.E.; Carbajal, F.C. Efectos Del Aguacate Como Fuente De Ácidos Grasos Monoinsaturados En Lípidos Séricos, Metabolismo De La Glucosa Y Reología En Pacientes Con Diabetes Tipo 2. Medicina Interna De Mexico 2008, 24(4), 267–272.
  • Li, Z.; Wong, A.; Henning, S.M.; Zhang, Y.; Jones, A.; Zerlin, A.; et al. Hass Avocado Modulates Postprandial Vascular Reactivity and Postprandial Inflammatory Responses to a Hamburger Meal in Healthy Volunteers. Food & Function 2013, 4(3), 384–391.
  • Fulgoni, V.L.; Dreher, M.; Davenport, A.J. Avocado Consumption Is Associated with Better Diet Quality and Nutrient Intake, and Lower Metabolic Syndrome Risk in US Adults: Results from the National Health and Nutrition Examination Survey (NHANES) 2001-2008. Nutrition Journal 2013, 12, 1.
  • Moher, D.; Liberati, A.; Tetzlaff, J.; Altman, D.G.; PRISMA Group. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement (Reprinted from Annals of Internal Medicine). Physical Therapy 2009, 89(9), 873–880.
  • Colquhoun, D.M.; Moores, D.; Somerset, S.M.; Humphries, J.A. Comparison of the Effects on Lipoproteins and Apolipoproteins of a Diet High in Monounsaturated Fatty Acids, Enriched with Avocado, and a High-Carbohydrate Diet. American Journal of Clinical Nutrition 1992, 56(4), 671–677.
  • Lerman-Garber, I.; Ichazo-Cerro, S.; Zamora-Gonzalez, J.; Posadas-Romero, C. Effect of a High-monounsaturated Fat Diet Enriched with Avocado in NIDDM Patients. Diabetes Care 1994, 17(4), 311–315.
  • Vázquez, A.; Ester, H.; Soralys, C.; Rosa, L.; Inciarte, G.; Coromoto, L. Efecto Del Consumo De Aguacate (Persea Americana Mill) Sobre El Perfil Lipídico En Adultos Con Dislipidemia Effect of Consumption of Avocado (Persea Americana Mill) on the Lipid Profile in Adults with Dyslipidemia. Anales Venezolanos De Nutrición 2009, 22(2), 84–89.
  • Pieterse, Z.; Jerling, J. C.; Oosthuizen, W.; Kruger, H.S.; Hanekom, S.M.; Smuts, C.M.; et al. Substitution of High Monounsaturated Fatty Acid Avocado for Mixed Dietary Fats during an Energy-restricted Diet: Effects on Weight Loss, Serum Lipids, Fibrinogen, and Vascular Function. Nutrition 2005, 21(1), 67–75.
  • Díaz Perilla, M.; Andrea Toro, C. Efecto De La Adición De Aguacate a La Alimentación Habitual Sobre Los Niveles De Lípidos En Personas Con Dislipidemia. Universitas Scientiarum 2004, 9(2), 49–58.
  • Graham, I.; Atar, D.; Borch-Johnsen, K.; Boysen, G.; Burell, G.; Cifkova, R.; et al. European Guidelines on Cardiovascular Disease Prevention in Clinical Practice: Executive Summary: Fourth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice. Constituted by R. European Heart Journal 2007 May 4, 28(19), 2375–2414.
  • World Health Organization. Obesity and Overweight. http://www.who.int/mediacentre/factsheets/fs311/en/ (accessed Oct 22, 2016).
  • Savage, J.S.; Marini, M.; Birch, L.L. Dietary Energy Density Predicts Women’ S Weight Change over 6 Y. American Journal of Clinical Nutrition 2008, 88, 677–684.
  • Naveh, E.; Werman, M.J.; Sabo, E.; Neeman, I. Defatted Avocado Pulp Reduces Body Weight and Total Hepatic Fat in Male Rats Fed Diets With cholesterol. The Journal of Nutrition 2002, 132(7), 2015–2018.
  • Kristensen, M.; Jensen, M.G. Dietary Fibres in the Regulation of Appetite and Food Intake. Importance of Viscosity. Appetite. 2011 Feb, 56(1), 65–70.
  • Lambert, J.E.; Parnell, J.A.; Tunnicliffe, J.M.; Han, J.; Sturzenegger, T.; Reimer, R.A. Consuming Yellow Pea Fiber Reduces Voluntary Energy Intake and Body Fat in Overweight/Obese Adults in a 12-Week Randomized Controlled Trial. Clinical Nutrition, 2016, 36(1),126–133.
  • Dewulf, E.M.; Cani, P.D.; Claus, S.P.; Fuentes, S.; Puylaert, P.G.; Neyrinck, A.M.; et al. Insight into the Prebiotic Concept: Lessons from an Exploratory, Double Blind Intervention Study with Inulin-type Fructans in Obese Women. Gut 2013 Aug, 62(8), 1112–1121.
  • Salgado, J.M.; Bin, C.; Mansi, D.N.; Souza, A. Efeito Do Abacate (Persea Americana Mill) Variedade Hass Na Lipidemia De Ratos Hipercolesterolêmicos. Ciência E Tecnologia De Alimentos 2008, 28(4), 922–928.
  • Dreher, M.L.; Davenport, A.J. Hass Avocado Composition and Potential Health Effects. Critical Reviews in Food Science and Nutrition 2013, 53(7), 738–750.
  • Marlett, J.A.; McBurney, M.I.; Slavin, J.L. Position of the American Dietetic Association. Journal of the American Dietetic Association 2002 Jul, 102(7), 993–1000.
  • Moussavi, N.; Gavino, V.; Receveur, O. Could the Quality of Dietary Fat, and Not Just Its Quantity, Be Related to Risk of Obesity? Obesity 2008 Jan, 16(1), 7–15.
  • Wien, M.; Haddad, E.; Oda, K.; Sabaté, J. A Randomized 3 × 3 Crossover Study to Evaluate the Effect of Hass Avocado Intake on Post-ingestive Satiety, Glucose and Insulin Levels, and Subsequent Energy Intake in Overweight Adults. Nutrition Journal 2013, 12, 155.
  • Coccia, E.; Varricchio, E.; Vito, P.; Turchini, G.M.; Francis, D.S.; Paolucci, M. Fatty Acid-specific Alterations in Leptin, Pparα, and CPT-1 Gene Expression in The. Rainbow Trout. Lipids 2014 Oct 10, 49(10), 1033–1046.
  • Keller, H.; Dreyer, C.; Medin, J.; Mahfoudi, A.; Ozato, K.; Wahli, W. Fatty Acids and Retinoids Control Lipid Metabolism through Activation of Peroxisome Proliferator-Activated Receptor-retinoid X Receptor Heterodimers. Proceedings of the National Academy of Sciences of the United States of America 1993 Mar, 90(6), 2160–2164.
  • Duarte Moreira Alves, R.; Boroni Moreira, A.P.; Silva, M.V.; Brunoro Costa, N.M.; Gonçalves Alfenas, R.D.C.; Bressan, J. High-oleic Peanuts Increase Diet-induced Thermogenesis in Overweight and Obese Men. Nutrición Hospitalaria 2014, 29(5), 1024–1032.
  • Bouchard, C.; Després, J.-P.; Mauriège, P. Genetic and Nongenetic Determinants of Regional Fat Distribution. Endocrine Reviews 1993 Feb, 14(1), 72–93.
  • Carvalho, C.P.; Bernal, J.E.; Velásquez, M.; Cartagena, J. Fatty Acid Content of Avocados (Persea Americana Mill. Cv. Hass) in Relation to Orchard Altitude and Fruit Maturity Stage. Agronomía Colombiana, 2015, 33(2), 220–227.
  • McIntyre, K.L.; Harris, C.S.; Saleem, A.; Beaulieu, L.-P.; Chieu, A.T.; Haddad, P.S.; et al. Seasonal Phytochemical Variation of Anti-glycation Principles in Lowbush Blueberry (Vaccinium Angustifolium). Planta Medica 2009, 75(3), 286–292.
  • Vita D.S.; Avellone, G.; Bongiorno, D.; Indelicato, S.; Massenti, R.; Lo, B.R. Quantitative Evaluation of the Phenolic Profile in Fruits of Six Avocado (Persea Americana) Cultivars by UHPLC-HESI-MS. International Journal of Food Properties,2016, 20(6), 1302–1312.
  • Peou, S.; Milliard-Hasting, B.; Sa, S. Impact of Avocado-enriched Diets on Plasma Lipoproteins: A Meta-Analysis. Journal of Clinical Lipidology [Internet] 2016 Jan, 10(1), 161–171.
  • Eckel, R.H.; Jakicic, J.M.; Ard, J.D.; De Jesus, J.M.; Houston Miller, N.; Hubbard, V.S.; et al. 2013 AHA/ACC Guideline on Lifestyle Management to Reduce Cardiovascular Risk. Journal of the American College of Cardiology 2014 Jul, 63(25), 2960–2984.
  • Moreno, J.J.; Mitjavila, M.T. The Degree of Unsaturation of Dietary Fatty Acids and the Development of Atherosclerosis (Review). Journal of Nutritional Biochemistry 2003, 14(4), 182–195.
  • Grant, W.C. Influence of Avocados on Serum Cholesterol. Proceedings of the Society for Experimental Biology and Medicine Society for Experimental Biology and Medicine (New York, NY) 1960, 104, 45–47.
  • Soares, H.F.; Ácido Graxo, O. Monoinsaturado Do Abacate No Controle Das Dislipidemias the Monounsaturated Fatty Acid from Avocado. Revista De Ciências Médicas 2000, 9(2), 47–51.
  • Parks, E.J.; Hellerstein, M.K. Carbohydrate-induced Hypertriacylglycerolemia: Historical Perspective and Review of Biological Mechanisms. The American Journal of Clinical Nutrition 2000, 71(2), 412–433.
  • Wang, C.S.; Hartsuck, J.; McConathy, W.J. Structure and Functional Properties of Lipoprotein Lipase. Biochimica Et Biophysica Acta 1992, 1123, 1–17.
  • Perona, J.S.; Covas, M.I.; Fitó, M.; Cabello-Moruno, R.; Aros, F.; Corella, D.; et al. Reduction in Systemic and VLDL Triacylglycerol Concentration after a 3-Month Mediterranean-Style Diet in High-cardiovascular-risk Subjects. Journal of Nutritional Biochemistry 2010, 21(9), 892–898.
  • Kendall, C.W.; Josse, A.R.; Esfahani, A.; Jenkins, D.J. Nuts, Metabolic Syndrome and Diabetes. The British Journal of Nutrition 2010, 104(4), 465–473.
  • Rashid, S.; Watanabe, T.; Sakaue, T.; Lewis, G.F. Mechanisms of HDL Lowering in Insulin Resistant, Hypertriglyceridemic States: The Combined Effect of HDL Triglyceride Enrichment and Elevated Hepatic Lipase Activity. Clinical Biochemistry 2003 Sep, 36(6), 421–429.
  • Lottenberg, A.M.P. Importância Da Gordura Alimentar Na Prevenção E No Controle De Distúrbios Metabólicos E Da Doença Cardiovascular. Arquivos Brasileiros De Endocrinologia & Metabologia 2009, 53(5), 595–607.
  • Yu-Poth, S.; Yin, D.; Kris-Etherton, P.M.; Zhao, G.; Etherton, T.D. Long-chain Polyunsaturated Fatty Acids Upregulate LDL Receptor Protein Expression in Fibroblasts and HepG2 Cells. The Journal of Nutrition 2005, 135(11), 2541–2545.
  • Vafa, M.R.; Haghighatjoo, E.; Shidfar, F.; Afshari, S.; Gohari, M.R.; Ziaee, A. Effects of Apple Consumption on Lipid Profile of Hyperlipidemic and Overweight Men. International Journal of Preventive Medicine 2011 Apr, 2(2), 94–100.
  • Kerckhoffs, D.A.; Hornstra, G.; Mensink, R.P. Cholesterol-lowering Effect of Beta-glucan from Oat Bran in Mildly Hypercholesterolemic Subjects May Decrease When Beta-Glucan Is Incorporated into Bread and Cookies. The American Journal of Clinical Nutrition 2003 Aug, 78(2), 221–227.
  • Rique, A.B.R.; Soares, E. de A.; Meirelles, C. de M. Nutrição E Exercício Na Prevenção E Controle Das Doenças Cardiovasculares. Revista Brasileira De Medicina Do Esporte. 2002, 8(6), 244–254.
  • Rull, A.; Camps, J.; Alonso-Villaverde, C.; Insulin Resistance, Inflammation, and Obesity: Role of Monocyte Chemoattractant Protein-1 (Orccl2) in the Regulation of Metabolism. Mediators of Inflammation 2010, 2010(2010) 1–11.
  • McLaren, J.E.; Michael, D.R.; Ashlin, T.G.; Ramji, D.P. Cytokines, Macrophage Lipid Metabolism and Foam Cells: Implications for Cardiovascular Disease Therapy. Progress in Lipid Research 2011 Oct, 50(4), 331–347.
  • Stoner, L.; Lucero, A.A.; Palmer, B.R.; Jones, L.M.; Young, J.M.; Faulkner, J. Inflammatory Biomarkers for Predicting Cardiovascular Disease. Clinical Biochemistry 2013 Oct, 46(15), 1353–1371.
  • Schnabel, R.; Blankenberg, S. Oxidative Stress in Cardiovascular Disease: Successful Translation from Bench to Bedside? Circulation 2007, 116(12), 1338–1340.
  • Villa-Rodríguez, J.A.; Molina-Corral, F.J.; Ayala-Zavala, J.F.; Olivas, G.I.; González-Aguilar, G.A. Effect of Maturity Stage on the Content of Fatty Acids and Antioxidant Activity of “Hass” Avocado. Food Research International 2011, 44(5), 1231–1237.
  • Duthie, S.J.; Jenkinson, A.M.; Crozier, A.; Mullen, W.; Pirie, L.; Kyle, J.; et al. The Effects of Cranberry Juice Consumption on Antioxidant Status and Biomarkers Relating to Heart Disease and Cancer in Healthy Human Volunteers. European Journal of Nutrition 2006, 45(2), 113–122.
  • Sen, C.K.; Packer, L. Antioxidant and Redox Regulation of Gene Transcription. The FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology 1996, 10(7), 709–720.
  • Rgm, S.; Gomes, A.C.; Naves, M.M.V.; Mota, J.F. Nuts and Legume Seeds for Cardiovascular Risk Reduction: Scientific Evidence and Mechanisms of Action. Nutrition Reviews 2015, 73(6), 335–347.
  • Scoditti, E.; Massaro, M.; Carluccio, M. A.; Pellegrino, M.; Wabitsch, M.; Calabriso, N.; et al. Additive Regulation of Adiponectin Expression by the Mediterranean Diet Olive Oil Components Oleic Acid and Hydroxytyrosol in Human Adipocytes. Plos One 2015, 10(6), e0128218.
  • Lawrence, T. The Nuclear Factor NF-kappaB Pathway in Inflammation. Cold Spring Harbor Perspectives in Biology 2009, 1(6), 1–10.
  • Baer, D.J.; Judd, J.T.; Clevidence, B.A.T.R. Dietary Fatty Acids Affect Plasma Markers of Inflammation in Healthy Men Fed Controlled Diets: Arandomized Crossover Study. The American Journal of Clinical Nutrition 2004, 79, 969–973.
  • Oliviero, F.; Spinella, P.; Fiocco, U.; Ramonda, R.; Sfriso, P.; Punzi, L. How the Mediterranean Diet and Some of Its Components Modulate Inflammatory Pathways in Arthritis. Swiss Medical Weekly 2015 Nov 2, 145, w14190.
  • Estruch, R. Anti-inflammatory Effects of the Mediterranean Diet: The Experience of the PREDIMED Study. Proceedings of the Nutrition Society 2010 Aug 2, 69(3), 333–340.
  • Martin-Ventura, J.L.; Madrigal-Matute, J.; Martinez-Pinna, R.; Ramos-Mozo, P.; Blanco-Colio, L.M.; Moreno, J.A.; et al. Erythrocytes, Leukocytes and Platelets as a Source of Oxidative Stress in Chronic Vascular Diseases: Detoxifying Mechanisms and Potential Therapeutic Options. Thrombosis and Haemostasis 2012, 108(3), 435–442.
  • Magdalon, J.; Vinolo, M.A.R.; Rodrigues, H.G.; Paschoal, V.A.; Torres, R.P.; Mancini-Filho, J.; et al. Oral Administration of Oleic or Linoleic Acids Modulates the Production of Inflammatory Mediators by Rat Macrophages. Lipids 2012, 47(8), 803–812.
  • Perdomo, L.; Beneit, N.; Otero, Y.F.; Escribano, Ó.; Díaz-Castroverde, S.; Gómez-Hernández, A.; et al. Protective Role of Oleic Acid against Cardiovascular Insulin Resistance and in the Early and Late Cellular Atherosclerotic Process. Cardiovascular Diabetology 2015 Dec 10, 14(1), 75.
  • Bellido, C.; López-Miranda, J.; Blanco-Colio, L.M.; Pérez-Martínez, P.; Muriana, F.J.; Martín-Ventura, J.L.; et al. Butter and Walnuts, but Not Olive Oil, Elicit Postprandial Activation of Nuclear Transcription Factor kappaB in Peripheral Blood Mononuclear Cells from Healthy Men. The American Journal of Clinical Nutrition 2004, 80(6), 1487–1491.
  • Salvadó, L.; Coll, T.; Gómez-Foix, A.M.; Salmerón, E.; Barroso, E.; Palomer, X.; et al. Oleate Prevents Saturated-fatty-acid-induced ER Stress, Inflammation and Insulin Resistance in Skeletal Muscle Cells through an AMPK-dependent Mechanism. Diabetologia 2013 Jun, 56(6), 1372–1382.
  • Milbury, P.E.; Vita, J.A.; Blumberg, J.B. Anthocyanins are Bioavailable in Humans following an Acute Dose of Cranberry Juice. The Journal of Nutrition 2010, 140(6), 1099–1104.
  • Denis, M.; Desjardins, Y.; Furtos, A.; Marcil, V.; Dudonné, S.; Montoudis, A.; et al. Prevention of Oxidative Stress, Inflammation and Mitochondrial Dysfunction in the Intestine by Different Cranberry Phenolic Fractions. Clinical Science [Internet] 2015, 128(3), 197–212.
  • Abbas, M.; Saeed, F.; Anjum, F.M.; Tufail, T.; Bashir, M.S.; Ishtiaq, A. Natural Polyphenols: An Overview. International Journal of Food Properties, 2016, 20(8), 1689–1699.
  • King, J.C.; Blumberg, J.; Ingwersen, L.; Jenab, M.; Tucker, K.L. Tree Nuts and Peanuts as Components of a Healthy Diet. The Journal of Nutrition 2008 Sep, 138(9), 1736S–1740S.
  • Berryman, C.E.; West, S.G.; Fleming, J.A.; Bordi, P.L.; Kris-Etherton, P.M. Effects of Daily Almond Consumption on Cardiometabolic Risk and Abdominal Adiposity in Healthy Adults with Elevated LDL-cholesterol: A Randomized Controlled Trial. Journal of the American Heart Association 2015, 4(1), e000993–e000993.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.