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Immunology

Expression of Interferon Epsilon in Mucosal Epithelium is Regulated by Elf3

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Pages 334-343 | Received 03 Jun 2024, Accepted 05 Jun 2024, Published online: 08 Jul 2024

References

  • Roberts RM. Interferon-tau, a Type 1 interferon involved in maternal recognition of pregnancy. Cytokine Growth Factor Rev. 2007;18:403–408. doi:10.1016/j.cytogfr.2007.06.010.
  • LaFleur DW, Nardelli B, Tsareva T, Mather D, Feng P, Semenuk M, Taylor K, Buergin M, Chinchilla D, Roshke V, et al. Interferon-kappa, a novel type I interferon expressed in human keratinocytes. J Biol Chem. 2001;276:39765–39771. doi:10.1074/jbc.M102502200.
  • Hertzog PJ. Type I interferons as primers, activators and inhibitors of innate and adaptive immune responses. Immunol Cell Biol. 2012;90:471–473. doi:10.1038/icb.2012.15.
  • Noppert SJ, Fitzgerald KA, Hertzog PJ. The role of type I interferons in TLR responses. Immunol Cell Biol. 2007;85:446–457. doi:10.1038/sj.icb.7100099.
  • Kato H, Sato S, Yoneyama M, Yamamoto M, Uematsu S, Matsui K, Tsujimura T, Takeda K, Fujita T, Takeuchi O, et al. Cell type-specific involvement of RIG-I in antiviral response. Immunity. 2005;23:19–28. doi:10.1016/j.immuni.2005.04.010.
  • Cai X, Chiu YH, Chen ZJ. The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling. Mol Cell. 2014;54:289–296. doi:10.1016/j.molcel.2014.03.040.
  • Cavlar T, Ablasser A, Hornung V. Induction of type I IFNs by intracellular DNA-sensing pathways. Immunol Cell Biol. 2012;90:474–482. doi:10.1038/icb.2012.11.
  • Hardy MP, Owczarek CM, Jermiin LS, Ejdebäck M, Hertzog PJ. Characterization of the type I interferon locus and identification of novel genes. Genomics. 2004;84:331–345. doi:10.1016/j.ygeno.2004.03.003.
  • Matsumiya T, Prescott SM, Stafforini DM. IFN-epsilon mediates TNF-alpha-induced STAT1 phosphorylation and induction of retinoic acid-inducible gene-I in human cervical cancer cells. J Immunol. 2007;179:4542–4549. doi:10.4049/jimmunol.179.7.4542.
  • Stifter SA, Matthews AY, Mangan NE, Fung KY, Drew A, Tate MD, Soares da Costa TP, Hampsey D, Mayall J, Hansbro PM, et al. Defining the distinct, intrinsic properties of the novel type I interferon, IFN. J Biol Chem. 2018;293:3168–3179. doi:10.1074/jbc.M117.800755.
  • Secombes CJ, Zou J. Evolution of interferons and interferon receptors. Front Immunol. 2017;8:209. doi:10.3389/fimmu.2017.00209.
  • Fung KY, Mangan NE, Cumming H, Horvat JC, Mayall JR, Stifter SA, De Weerd N, Roisman LC, Rossjohn J, Robertson SA, et al. Interferon-epsilon protects the female reproductive tract from viral and bacterial infection. Science. 2013;339:1088–1092. doi:10.1126/science.1233321.
  • Gearing LJ, Cumming HE, Chapman R, Finkel AM, Woodhouse IB, Luu K, Gould JA, Forster SC, Hertzog PJ. CiiiDER: a tool for predicting and analysing transcription factor binding sites. PLoS One. 2019;14:e0215495. doi:10.1371/journal.pone.0215495.
  • Matys V, Kel-Margoulis OV, Fricke E, Liebich I, Land S, Barre-Dirrie A, Reuter I, Chekmenev D, Krull M, Hornischer K, et al. TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes. Nucleic Acids Res. 2006;34:D108–10. doi:10.1093/nar/gkj143.
  • Chiang SY, Burli RW, Benz CC, Gawron L, Scott GK, Dervan PB, Beerman TA. Targeting the ets binding site of the HER2/neu promoter with pyrrole-imidazole polyamides. J Biol Chem. 2000;275:24246–24254. doi:10.1074/jbc.M000820200.
  • Sementchenko VI, Watson DK. Ets target genes: past, present and future. Oncogene. 2000;19:6533–6548. doi:10.1038/sj.onc.1204034.
  • Ng AY, Waring P, Ristevski S, Wang C, Wilson T, Pritchard M, Hertzog P, Kola I. Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epithelium. Gastroenterology. 2002;122:1455–1466. doi:10.1053/gast.2002.32990.
  • Wu J, Duan R, Cao H, Field D, Newnham CM, Koehler DR, Zamel N, Pritchard MA, Hertzog P, Post M, et al. Regulation of epithelium-specific ETS-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation. Cell Res. 2008;18:649–663. doi:10.1038/cr.2008.57.
  • Demers A, Kang G, Ma F, Lu W, Yuan Z, Li Y, Lewis M, Kraiselburd EN, Montaner L, Li Q. The mucosal expression pattern of interferon-epsilon in rhesus macaques. J Leukoc Biol. 2014;96:1101–1107. doi:10.1189/jlb.3A0214-088RRR.
  • Wei GH, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, et al. Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. EMBO J. 2010;29:2147–2160. doi:10.1038/emboj.2010.106.
  • Oikawa T, Yamada T. Molecular biology of the ETS family of transcription factors. Gene. 2003;303:11–34. doi:10.1016/s0378-1119(02)01156-3.
  • Oettgen P, Alani RM, Barcinski MA, Brown L, Akbarali Y, Boltax J, Kunsch C, Munger K, Libermann TA. Isolation and Characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ETS family. Mol Cell Biol. 1997;17:4419–4433. doi:10.1128/MCB.17.8.4419.
  • Tymms MJ, Ng AY, Thomas RS, Schutte BC, Zhou J, Eyre HJ, Sutherland GR, Seth A, Rosenberg M, Papas T, et al. A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer. Oncogene. 1997;15:2449–2462. doi:10.1038/sj.onc.1201427.
  • Kushwah R, Oliver JR, Wu J, Chang Z, Hu J. Elf3 regulates allergic airway inflammation by controlling dendritic cell-driven T cell differentiation. J Immunol. 2011;187:4639–4653. doi:10.4049/jimmunol.1101967.
  • Shatnawi A, Norris JD, Chaveroux C, Jasper JS, Sherk AB, McDonnell DP, Giguère V. ELF3 is a repressor of androgen receptor action in prostate cancer cells. Oncogene. 2014;33:862–871. doi:10.1038/onc.2013.15.
  • Kim S, Choi Y, Spencer TE, Bazer FW. Effects of the estrous cycle, pregnancy and interferon tau on expression of cyclooxygenase two (COX-2) in ovine endometrium. Reprod Biol Endocrinol. 2003;1:58. doi:10.1186/1477-7827-1-58.
  • Yuan JS, Reed A, Chen F, Stewart CN. Jr. Statistical analysis of real-time PCR data. BMC Bioinformatics. 2006;7:85. doi:10.1186/1471-2105-7-85.

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