16
Views
41
CrossRef citations to date
0
Altmetric
Original Articles

Amoxycillin/Clavulanic Acid: a Review of its Efficacy in over 38,500 Patients from 1979 to 1992

, &
Pages 67-93 | Published online: 15 Jul 2016

References

  • Todd PA, Iknfield P. Amoxicillin/clavulanic acid: an update of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs 1990; 39 (2): 264–307.
  • Brogden RN, Carmine A, Heel RC, Morley PA, Speight TM. Amoxycillin/clavulanic acid: a review of the antibacterial activity, pharmacokinetics and therapeutic use. Drugs 1981; 22: 337–362.
  • Chalmers TC, Smith H, Blackburn B, et al. A method for assessing the quality of a randomized control trial. Controlled Clinical Trials 1981; 2: 31–49.
  • L’Abbé K, Detsky AS, O’Rourke K. Meta-analysis in clinical research. Ann Intern Med 1987; 107: 224–233.
  • Abbas AMA, Goel PK, Venkit N, Gowers E. Augmentin therapy in the treatment of urinary tract infections in general practice. Br J Clin Pract 1984; 38 (2): 49–51.
  • Abbas AMA, Chandra V, Dongaonkar PP, et al. Ciprofloxacin versus amoxycillin/clavulanic acid in the treatment of urinary tract infections in general practice. J Antimicrob Chemother 1989; 24: 235–239.
  • Acar JF, Goldstein FW, Goldstein FW. Augmentin in the control of urinary tract infections caused by resistance to amoxycillin. Proc 13th Int Congr Chemother Vienna 1983; (22); 59.
  • Agrawal SK, Jain S, Sahai J. Clavulanic acid potentiated amoxycillin (Augmentin) in the treatment of urinary tract infections. Antiseptic 1987; (Jan): 18–21.
  • Agren K, Lundberg C, Nord CE. Effect of amoxycillin-/clavulanic acid on the aerobic and anaerobic tonsillar microflora in the treatment of recurrent tonsillitis. Scand J Infect Dis 1990; 22: 691–697.
  • Aigner K, Schindl R, Mittermayer H. Augmentin in acute exacerbations of chronic bronchitis. J Int Med Res 1984; 12 (6): 321–326.
  • Aigner K, Mittermayer IIW, Schindl R. Experience with Augmentin in the treatment of chronic bronchitis and bronchopneumonia. Proc Eur Symp Augmentin Scheveningen 1982; Excerpta Med Curr Clin Pract Ser 1983; No. 4: 267–277.
  • Al Roomi LG, Sutton AM, Cockburn F, Mcallister TA. Amoxycillin and clavulanic acid in the treatment of urinary infection. Arch Dis Child 1984; 59 (3): 256–259.
  • Allegra L, Grassi C, Grossi E, et al. Ruolo degli antibiotici nel trattamento delle riacutizzazioni della bronchite cronica: risultati di uno studio Italiano multicentrics (the role of antibiotics in the treatment of chronic bronchitis exacerbation: follow-up of a multicenter study). G Ital Mal Torace 1991; 45 (3): 138–148.
  • Amendola F, Natuzzi M, De Mattia D, Schettini F. Pediatric suspension of amoxycillin and clavulanic acid in the treatment of bacterial infections of the upper respiratory tract and ear. Minerva Pediatr 1989; 41 (2): 97–103.
  • Ancill RJ, Ballard JH, Capewell MA. Urinary tract infections in geriatric inpatients: A comparative study of amoxycillin-clavulanic acid and cotrimoxazole. Curr Ther Res Clin Exp 1987; 41 (4): 444–448.
  • Anyanwu CH, Umeh BUO. A clinical evaluation of clavulanate-potentiated amoxycillin in the management of moderate to severe respiratory tract infections. J Int Med Res 1988; 16: 210–215.
  • Appelman CLM, Claessen JQPJ, Touw-Otten FWMM, Hordijk GJ, De Melker RA. Co-amoxiclav in recurrent acute otitis media: placebo controlled study. Br Med J 1991; 303: 1450–1452.
  • Arai S, Konishi K, Nishioka K, Takishima T. Clinical effects of BRL25000 (clavulanic acid-amoxicillin) on chronic respiratory infections caused by haemophilus influenzae. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 168–175.
  • Arguedas AG, Zaleska M, Stutman HR, Blumer JL, Hains CS. Comparative trial of cefprozil vs. amoxicillin clavulanate potassium in the treatment of children with acute otitis media with effusion. Pediatr Infect Dis J 1991; 10 (5): 375–380.
  • Arkoulis T, Tzingounis V. Acute urinary tract infection in pregnant women treated with clavulanate and potentiated amoxycillin. Proc 16th Int Congr Chemother Jerusalem 1989.
  • Aronovitz GH. Safety and efficacy of Augmentin in the treatment of streptococcal pharyngitis. Postgrad Med 1984; (Augmentin Symp Suppl): 257–258.
  • Askew C, Lomax J, Lawson W, Kingston RD. Effectiveness of two therapeutic antibiotic regimens in the treatment of serious post-operative infections. Br J Clin Pract 1989; 43 (12): 438–442.
  • Astruc J. Efficaciete et tolerance d’une nouvelle formulation d’amoxicilline 100 mg-acide clavulanique 12,5 mg dans les otitis aigues du nourrissone (Effectiveness and safety of a new formulation containing 100 mg amoxicillin-12.5 mg clavulanic acid in infants with acute otitis media). Ann Pediatr 1992; 39 (2): 142–148.
  • Aten EM, Neu HC. A multicenter, double-blind comparative study of amoxicillin/clavulanic acid and cefaclor in the treatment of skin and skin structure infections. Postgrad Med 1984; (Augmentin Symp Suppl): 147–155.
  • Baba S, Murai K, Kinoshitah, et al. Evaluation of BRL25000 (clavulanic acid-amoxicillin) in acute purulent otitis media and acute exacerbation of chronic otitis media: a comparative double blind study with amoxicillin. Chemotherapy (Tokyo) 1983; 31 (Suppl 2): 97–112.
  • Baba S. Clinical studies on Augmentin in the treatment of otorhinolaryngological infections. Augmentin: Proc Int Symp Montreux Switzerland, July 1981 Eds. Leigh DA and Robinson OPW, Excerpta Medica: 149–155.
  • Badelon O, Bingen E, Sauzeau C, Lambert-Zechovsky N, De Ribier A, Bensahel H. First line antibiotic treatment in bone and joint sepsis in children (Choix de l’antibiotherapie de premiere intention dans le traitement des infections osseuses et articulaires de l’enfant). Pathol Biol 1988; 36: 746–749.
  • Bailey RR, Bishop V, Peddie B, Chambers PFM, Davies PR, Crofts HG. Comparison of Augmentin with cotrimoxazole for treatment of uncomplicated urinary tract infections. NZ Med J 1983; 96: 970–972.
  • Balasubramaniam S, Velayos E, Lakshmanan S, Chuah SK, Bansal MB, Thadepalli H. Clinical evaluation of Augmentin therapy in anaerobic infection of skin and soft tissue. Proc 14th Int Congr Chemother Kyoto 1986: 1284–1285.
  • Ball AP, Mehtar S, Watson A. Clinical efficacy and tolerance of Augmentin in soft tissue infection. J Antimicrob Chemother 1982; 10 (1): 67–74.
  • Ball AP, Watson T, Mentar S. Amoxycillin and clavulanic acid in intra-abdominal and pelvic sepsis. J Antimicrob Chemother 1981; 7 (4): 441–444.
  • Ball AP, Geddes AM, Davey PG, Farrell ID, Brookes GR. Clavulanic acid and amoxicillin: a clinical, bacteriological and pharmacological study. Lancet 1980; i: 620–623.
  • Balmes P, Clerc G, Dupont B, Labram C, Pariente R, Poirier R. Comparative study of azithromycin and amoxicillin/clavulanic acid in the treatment of lower respiratory tract infections. Eur J Clin Microbiol Infect Dis 1991; 10: 437–439.
  • Baranski MC, Baranski NC, Baranski Filho MC. Treatment of bacterial diseases common in general practice with BRL-25000 (amoxycillin/potassium clavulanate). Arq Bras Med 1983; 57 (2): 105–109.
  • Basta M, Drozdz W, Gedliczka M, Heczko PB. Evaluation of Augmentin in treatment of lower extremity infections in diabetic patients. Proc 7th Mediterr Congr Chemother Barcelona 1990; (20–25 May): Abstr: 159.
  • Bee LH, Phang T. Treatment of uncomplicated gonococcal urethritis in males with two doses of Augmentin, six hours apart. Singapore Med J 1985; 26: 147–149.
  • Beeuwkes H, Rutgers VH. A combination of amoxycillin and clavulanic acid in the treatment of respiratory tract infections caused by amoxycillin-resistant haemophilus influenzae. Infection 1981; 9 (5): 244–248.
  • Begue P, Astruc J, Barthe P, et al. Traitement des pyelonephrites aigues (P.A.) de l’enfant (Enf.) – etude multicentrique comparative amoxicilline-acide clavulanique (A-Ca)-versus amoxicilline plus netilmicine (A + N). Reun Interdiscip Chimiother Antiinfect 1987; Paris 3 December Abstr 181/C10 Page 234.
  • Begue P, Lacroix J. Essai comparatif multicentrique du cefuroxime axetil en suspension versus amoxicilline/acide clavulanique dans l’infection respiratoire de l’enfant (cefuroxime axetil and respiratory tract infection: results of a multicentre trial conducted in pediatric offices). Med Mal Infect 1991; 21: 75–78.
  • Begue P, Broussin B, Quinet B, Garabedian N, Sounthavong JP, Riviere F. Otites moyennes aiguës de l’enfant: etude clinique randomisee et ouverte de l’efficacite de deux antibiotiques majeurs, (ethylsuccinate d’erythromycine/acetyl-sulfafurazole versus amoxicilline/acide clavulanique). Ann Pediatr 1990; 37 (2): 127–130.
  • Benard Y, Brambilla C, Bonnaud F, Guerin JC, Aubertin J. Etude comparative du cefadroxil et de l’association amoxicilline – acide clavulanique dans le traitement des surinfections aigues de bronchopneumopathies chroniques de l’adulte. (Comparative study of cefadroxil and a combination of amoxycillin and clavulanic acid in the treatment of acute superinfections in chronic pulmonary disease in adults). Med Mal Infect 1991; 21: 350–358.
  • Beumer HM, Sips AP, Mathijsen A. Miraxid versus Augmentin in exacerbations of chronic bronchitis. Drugs Exp Clin Res 1984; 10 (5): 351–356.
  • Beumer HM. Cefixime versus amoxicillin/clavulanic acid in lower respiratory tract infections. Int J Clin Pharmacol Ther Toxicol 1989; 27 (1): 30–33.
  • Bisetti A, Grassi L, Romano V, Scacciavillani E. Therapy of pulmonary bacterial infections with amoxicillin and clavulanic acid: clinical experience. Arch Monaldi 1987; 42 (6): 505–514.
  • Bocazzi A, Borzani M, Scotti L. Amoxycillin-clavulanic acid combination in upper respiratory tract bacterial infections in pediatric patients. A controlled clinical study. Pediatr Med Chir 1988; 10 (4): 395–400.
  • Boccazzi A, Bosi M, Piceci E, et al. Trattamento antibiotico dell’otite media nel bambino: confronto tra l’associazione amoxicillina-acido clavulanico e l’eritromicina. Farm Ter 1990; VII (1): 44–48.
  • Bonsignore G, Ferrara G, Bellia V, Scaglione T. Use of amoxycillin-clavulanic acid (Augmentin) in the treatment of adult patients with acute or chronic exacerbated lower respiratory tract infections. Proc 6th Mediterr Congr Chemother Taormina 1988; Page 17 Abstr 36.
  • Borderon JC, Ramponi N, Ployet MJ, Despert F, Bloc D, Laughier J. A clinical trial of amoxycillin + clavulanic acid in pediatric patients. Ann Pediatr 1985; 32 (10): 895–899.
  • Boschi G, Zanacca C, Bartoli G, et al. Cefaclor vs amoxicillina + acido clavulanico nelle infezioni respiratorie in eta pediatricac(cefaclor vs amoxicillin and clavulanic acid in respiratory infections in paediatric age). Gazz Med Ital Arch Sci Med 1992; 151 (1–2): 11–15.
  • Bossi R, Beretta F, Vaghi A, et al. Studio dell’efficacia e della tollerabilità di un’associazione amoxicillina-acido clavulanico in pazienti broncopatici cronici riacutizzati. Ital J Chest Dis 1989; 43 (4): 271–277.
  • Boston PF, Gowers E, Rose AJ. Augmentin compared with oxytetracycline for chest infections in general practice. Br J Dis Chest 1986: 80(2); 148–156.
  • Brakenbury PH, Muwanga C. A comparative double blind study of amoxycillin/clavulanate vs placebo in the prevention of infection after animal bites. Arch Emerg Med 1989; 6: 251–256.
  • Brambilla C, Kastanakis S, Knight S, Cunningham K. Cefuroxime and cefuroxime axetil versus amoxicillin plus clavulanic acid in the treatment of lower respiratory tract infections. Eur J Clin Microbiol Infect Dis 1992; 11 (2): 118–124.
  • Brambilla C, Guerin JC, Bonnaud F, Benard Y, Aubertin J. Comparative trial of cefadroxil and a combination of amoxycillin and clavulanic acid in the treatment of acute community-acquired pulmonary infections presumed to be pneumococcal. Med Mal Infect 1991; 21; 342–349.
  • Britton M. Comparison of intravenous cefuroxime followed by cefuroxime axetil versus Augmentin (intravenous then oral) in the treatment of lower respiratory tract infections. Proc 7th Mediterr Congr Chemother Barcelona 1990; (20–25 May), Abstr: 163.
  • Bromberg K, Worku M, Gullans CR, Sierra MF. Augmentin (amoxicillin/potassium clavulanate) for the therapy of paediatric skin and soft tissue infections. Postgrad Med 1984; (Augmentin Symp Suppl): 235–238.
  • Brook I. Treatment of patients with acute recurrent tonsillitis due to group a beta-haemolytic streptococci: a prospective randomized study comparing penicillin and amoxycillin/clavulanate potassium. J Antimicrob Chemother 1989; 24 (2): 227–233.
  • Brumfitt W, Hamilton-Miller JMT. Changing role of cotrimoxazole in the treatment of recurrent urinary infections: a comparison with Augmentin. Br J Clin Pract 1985; 39 (9): 346–351.
  • Brumfitt W, Hamilton-Miller JMT. Amoxicillin plus clavulanic acid in the treatment of recurrent urinary tract infections. Antimicrob Agents Chemother 1984; 25 (2): 276–278.
  • Brumfitt W, Hamilton-Miller JMT. Comparative study of cephradine and amoxicillin-clavulanate in the treatment of recurrent urinary tract infections. Antimicrob Agents Chemother 1990; 34 (9): 1803–1805.
  • Buchi W, Casey PA. Experience with parenteral and sequential parenteral-oral amoxicillin/clavulanate (Augmentin) in hospitalized patients. Infection 1988; 16 (5): 306–312.
  • Buisson PH, Valette C, et al. Traitement des infections genitales hautes de la femme: etude multicentrique de 1, efficacite et de la tolerance comparees de l’association amoxicilline-acide clavulanique et d’une triple association antibiotique. Rev Fr Gynecol Obstet 1989; 84 (10): 699–703.
  • Capecchi V. Clinical evaluation of an amoxicillin-clavulanic acid combination in respiratory tract infections. Clin Ter 1987; 120 (3): 211–218.
  • Cardenas JV, Markowitz N, Salo S, Del Busto R, Madhavan T, Fisher E, Quinn EL. Clinical evaluation of Augmentin (amoxycillin + clavulanic acid). Proc 21st Interscience Conf Antimicrob Agents Chemother Chicago 1981; Abstr 447.
  • Carles P, Courty G, Godard P, et al. Efficacite et tolerance de l’Augmentin dans les surinfections bronchiques chez l’insuffisant respiratoire chronique). Gaz Med Fr 1987; 94 (43): 69–73.
  • Casali L, Consiglio M, Pasi M et al. Amoxycillin + clavulanic acid in the treatment of lower respiratory tract infections (LRTI): a multicentre study. Proc 17th Int Congr Chemother Berlin 1991; A1020.
  • Casas Rodriguez J, Pallares Robles J, Guarga Rjas A, et al. Amoxicilina/acido clavulanico y trimethoprim en el tratamiento de la infeccion urinaria en atencion primaria. Atencion Primaria 1990; 7: 127–130.
  • Casey PA, Walther M. Comparison of amoxycillin-/clindamycin with Augmentin in treatment of non-puerperal breast abscesses in women. Proc 23rd Interscience Conf Antimicrob Agents Chemother Las Vegas 1983; Abstr No. 850.
  • Catalano GB, Serra A, La Mantia I. Use of amoxycillin and clavulanic acid combination in the infections of the otorhinolaryngological area. Riv Ital Otorinolaryngol Audiol Foniatr 1988; 8 (4): 359–365.
  • Cervenova O, Chocholova M, Dzurikova V. Klinicke sledovanie Augmentinu pri infekciach mocovych ciest u deti. Cs Pediatr 1990; 45: 169–171.
  • Chan KH, Mandel EM, Rockette HE, et al. A comparative study of amoxicillin-clavulanate and amoxicillin treatment of otitis media with effusion. Arch Otolaryngol Head Neck Surg 1988; 114 (2): 142–146.
  • Chardon H, Poirier R, Lagier E, Jacqueme P. Traitement des bronchopneumonies de l’adulte par l’augmentin intraveineux. Reun Interdiscip Chimiother Antiinfect 1987; Paris 3 December Abstr 120/P7 Page 173.
  • Cho K, Sakata H, Fujita K, Yoshioka H, Mukai N. Laboratory and clinical studies on BRL 25000 (clavulanic acid-amoxycillin) granules in the pediatric field. Jpn J Antibiot 1985; 38 (2): 253–262.
  • Cho N, Fukunaga K, Kunii K. Clinical studies on BRL25000 (clavulanic acid-amoxicillin) in the field of obstetrics and gynecology. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 548–566.
  • Cho N, Fukunaga K, Kunii K. Fundamental and clinical studies on Brl 25000 (clavulanic acid-amoxicillin) in the field of obstetrics and gynecology. Jpn J Antibiot 1983; 36: 481–486.
  • Chomarat M, Dubreuil C. Traitement des otites moyennes aigues: etude comparative de l’efficacite de la cefatrizine et de l’amoxicilline-acide clavulanique (treatment of acute otitis media: comparative study of the efficacy of cefatrizine and amoxycillin-clavulanic acid). Pathol Biol 1991; 39 (5): 555–557.
  • Chomarat M, Dubost J, Kalfon F. Etude randomisee de l’association amoxicilline-acide clavulanique versus amoxicilline + metronidazole dans les cellulites de la face d’origine dentaire. Pathol Biol 1991; 39 (5): 558–560.
  • Cioffi R, Turco D, Alfano B, Di Salvatore F, Gnasso P, Mastroianni S. Treatment of respiratory tract infections with Augmentin. Proc 6th Mediterr Congr Chemother Taormina 1988; Abstr 446: 281.
  • Ciraru-Vigneron N, Barrier J, Becue J, et al. Amoxycillin/clavulanic acid («Augmentin») compared with a combination of aminopenicillin, aminoglycoside and metronidazole in the treatment of pelvic inflammatory disease. Pharmathera-peutica 1989; 5 (5): 312–319.
  • Cohen R, Lebeaut A, Narcy P. Treatment of acute otitis media by an oral pediatric suspension of amoxicillin-clavulanic acid. Ann Pediatr 1989; 36 (1): 49–54.
  • Conde Redondo F, Gomez Garcia S, Alvarez Garcia J, Valbuena Crespo C. La asociacion amoxicilina mas clavulanico en el tratamiento de la infeccionurinaria en pediatría. Pediatrika 1989; 9 (7): 41–46.
  • Contardi I. Eradicazione di streptococco B emolitico di gruppo a con amoxicillina piu acido clavulanico dopo fallimento della terapia orale con eritromicina o penicillina v in infezioni orofgaringee (eradication of B haemolytic streptococcus group a with amoxicillin and clavulanate potassium after failure of oral therapy with erythromycin or penicillin v in oropharynx infections). G Mal Infett Parassit 1990; 42 (2): 109–111.
  • Contardi I, Nastri A. Amoxycillin/clavulanic acid in the treatment of pneumonia in children. Proc 7th Mediterr Congr Chemother Barcelona 1990; 20–25 May: Abstr 158.
  • Cooper J, Raeburn A, Brumfitt W, Hamilton-Miller JMT. Single dose and conventional treatment for acute bacterial and non-bacterial dysuria and frequency in general practice. Infection 1990; 18 (2): 65–69.
  • Crokaert F, Van Der Linden MP, Yourassowsky E. Activities of amoxicillin and clavulanic acid combinations against urinary tract infections. Antimicrob Agents Chemother 1982; 22 (2): 346–349.
  • D’Adda D, Maruzzi MM, Pravettoni G, Raiteri D, Carotenuto E. Clinical evaluation of a new combination of amoxicillin and clavulanic acidin treatment of lower respiratory tract infections. G Ital Mal Torace 1989; 43 (1): 33–36.
  • D’Costa LJ, Ndinya-Achola JO, Haase D, Fransen L, Nsanze H. Treatment of PPNG with 4 regimens involving Augmentin with or without probenecid and penicillin + probenecid with or without a small dose of Augmentin. Afr J Sex Trans Dis 1986; (Feb): 21–22.
  • Dagan R, Bar-David Y. Comparison of amoxicillin and clavulanic acid (Augmentin) for the treatment of nonbullous impetigo. Am J Dis Child 1989; 143 (8): 916–918.
  • Dalet F, Del Rio G. A clinical evaluation of the association amoxycillin and clavulanic acid in the treatment of urinary infections. Proc 13th Int Congr Chemother Vienna 1983; 97: 47–51.
  • Dambro N, Friedman AD, Alexander ER, Harrison HR. Augmentin therapy for urinary tract infections in children. Postgrad Med 1984; (Augmentin Symp Suppl): 263–266.
  • Daniel RR, et al. Comparison of the efficacy, safety and toleration of azithromycin and Augmentin in the treatment of childhood otitis media. Proc 7th Mediterr Congr Chemother Barcelona 1990; 20–25 May: Abstr 100.
  • Dautzenberg B, Scheimberg A, Brambilla CH, et al. Comparison of 2 oral antibiotics, roxithromycin and amoxycillin plus clavulanic acid, in lower respiratory tract infections. Proc 17th Int Congr Chemother Berlin 1991; A755.
  • Davies JG, Rose AJ, Walker GD. A comparison of Augmentin and cotrimoxazole in the treatment of adult infections in general practice. Br J Clin Pract 1982; 36 (11–12): 387–404.
  • De Almeida Esmeraldo P, Meira MCM, Gonzaga MA. Evaluation of clavulin in pediatric infections. Folha Med 1985; 90 (3): 145–149.
  • De Silva AH, Bashi SAQ, Basu Roy R. Treatment of uncomplicated anogenital gonorrhoea with a single oral dose of 3g amoxycillin combined with 250mg clavulanic acid. Br J Vener Dis 1984; 60 (2): 132–133.
  • Debray H, Galland A. Experience with Augmentin in the treatment of infections in children. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983; No. 4: 347–353.
  • Decker K. Clinical results of the treatment of pelvic inflammatory disease with oral formulations of Augmentin or ciprofloxacin. Proc 2nd Biennial Conf Chemother Infect Dis Malig Montreux 1989: 72.
  • Degae R, Shalit I, Kinhorn M, et al. Prospective, randomized, comparative study of amoxycillin-clavulanate versus standard antibiotic therapy for the treatment of septic arthritis and osteomyelitis in pediatric patients. Proc 7th Mediterr Congr Chemother Barcelona 1990; (20–25 May), Abstr: 90.
  • Delorme N, Beck G, Chabot F, Guenoun P, Polu JM, Sadoul P. Oral antimicrobial chemotherapy amoxycilline in the chronic bronchitis traitement des poussees infectieuses de la bronchite chronique par amoxicilline + clavulanate (Augmentin). Ann Med Nancy Est 1987; 26: 299–302.
  • Derluyn J. Clinical experience with 3 dosage regimens of oral Augmentin in patients with urinary tract infections. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983; No. 4: 183–191.
  • Dickie AS, Lang SDR. Pilot study of single dose Augmentin for acute bacterial cystitis. NZ Med J 1986; 99 (807): 600.
  • Dixon JM. Outpatient treatment of non-lactational breast abscesses. Br J Surg 1992; 79 (1): 56–57.
  • Du Plessis DJ, Cilliers D, Van Rensburg AJ, Lindeque K, Kritzinger NA. An evaluation of Augmentin, in the treatment of urinary tract infections, occurring in patients with spinal injuries. Augmentin: Proc Int Symp Montreux Switzerland, July 1981 Eds. Leigh DA and Robinson OPW, Excerpta Medica: 78–85.
  • El Filali KM, El M’daghri N, El Kabli H, Hajji M, Benbachir M, Himmich H. Efficacy and tolerance of intravenous amoxycillin/clavulanic acid in adults. Pharmatherapeutica 1989; 5 (5): 329–337
  • Elliot PJ, Reeves DS, Holt HA, Chapman ST, Bywater MJ. Evaluation of Augmentin in respiratory tract infections. Proc 1st Symp Augmentin Excerpta Med Int Cong Set Excerpta Med Int Cong Ser 1980; Proc 1st Symp Augmentin 270–274.
  • Ellis-Pegler RB, Lang SDR, Downey DJ, Anderson MPR. Augmentin treatment of bacterial infections in hospitalised patients. NZ Med J 1982; 95: 542–545.
  • Engelhard D, Cohen D, Strauss N, Sacks TG, Jorczak-Sarni L, Shapiro M. Randomised study of myringotomy, amoxycillin/clavulanate, or both for acute otitis media in infants. Lancet 1989; II (8655): 141–143.
  • Esposito S, Noviello S, D’Errico G, Montanaro C. Amoxicillin/clavulanic acid (Augmentin) for treatment of upper and lower respiratory tract infections. Proc 7th Mediterr Congr Chemother Barcelona 1990; 20–25 May: Abstr 156.
  • Faro S, Pastorek J, Aldridge K. Open efficacy and tolerance study of Augmentin in the treatment of urinary tract infections. Postgrad Med 1984; Augmentin Symp Suppl: 195–198.
  • Fast MV, Nsanze H, D’Costa LJ, et al. Treatment of chancroid by clavulanic acid with amoxycillin in patients with beta-lactamase positive Haemophilus ducreyi infection. Lancet 1982; ii: 509–511.
  • Federspil P. Augmentan in ENT infections. Augmentan: Symposiumsband Karlsruhe: 1982; Frankfurt-Main: Zurich: PMI-Pharm & Medical Information, 1983: 76–85.
  • Feist H. Sequential therapy with iv and oral ofloxacin in lower respiratory tract infections: a comparative study. Infection 1991; 19 (Suppl. 7): S380–S383.
  • Feldman W, Sutcliffe T, Dulberg C. Twice-daily antibiotics in the treatment of acute otitis media: trimethoprim-sulfamethoxazole versus amoxicillin-clavulanate. Can Med Assoc J 1990; 142 (2): 115–118.
  • Fernandez H, Claquin C, Guibert M, Papiernik E. Suspected postpartum endometritis: a controlled clinical trial of single-agent antibiotic therapy with Amox-CA (Augmentin) vs. ampicillin-metronidazole ± aminoglycoside. Eur J Obstet Gyne Reprod Biol 1990; 36: 69–74.
  • Fink M, Casey PA. The treatment of pneumonia and urinary tract infections in hospitalized children. Augmentan: Symposiumsband Karlsruhe: 1982; Frankfurt-Main: Zurich: PMI-Pharm & Medical Information, 1983: 86–90.
  • Fiocchi A, Zuccotti G, Bellu R, Marangione P, Riva E, Giovannini M. Treatment of respiratory tract infections in children: a study of a combination of amoxycillin and clavulanic acid. J Int Med Res 1990; 18 (4): 326–333.
  • Fior R, Tamburini P, Veljak C, Zocconi E. The association of amoxicillin clavulanic acid in the management of bacterial infections of the middle ear and parasinasal sinuses in pediatric age. Riv Ital Otorinolaryngol Audiol Foniatr 1989; 9 (1): 84–87.
  • Fischbach M, Hamel G, Jehl F, et al. Infection urinaire febrile (temperature superieure a 38,5 degree) chez l’enfant: experience clinique, biologique et bacteriologique d’une antibiotherapie intraveineuse limitee a 3 jours. Med Hyg 1992; 50 (1921): 432–434.
  • Fischbach M, Simeoni U, Mengus L, et al. Urinary tract infections with tissue penetration in children: cefotaxime compared with amoxycillin/clavulanate. J Antimicrob Chemother 1989; 24 (Suppl.B): 177–183.
  • Flavell Matts SG, Fancourt GJ, Mitchell CJ, Gowers E, Boston PF. Further data on Augmentin and cotrimoxazole in the treatment of urinary tract infection. Br J Clin Pract 1985; 39 (5): 179–184.
  • Fleisher G, Scott P, Wilmott C, Campos J. Amoxycillin combined with clavulanic acid for the treatment of urin ry tract infections in children. Postgrad Med 1984; Augmentin Symp Suppl: 219–223.
  • Fleisher GR, Wilmott CM, Campos JM. Amoxycillin combined with clavulanic acid for the treatment of soft tissue infections in children. Antimicrob Agents Chemother 1983; 24 (5): 679–681.
  • Flores Guerrero R. Evaluation of Augmentin in the treatment of adult patients with bacterial infections. Invest Med Int 1983; 10 (3): 260–263.
  • Freitas E Costa M, Correia I, Goncalves JR. Clinical evaluation of amoxycillin + clavulanic acid in the treatment of lower respiratory tract infections in ambulatory patients: personal experience. Proc 6th Mediterr Congr Chemother Taormina 1988; Abstr 287: Page 253.
  • Frigerio D, Nastri A, Paizis G. Open, multicentre study on the efficacy and tolerability of amoxicillin and clavulanic acid in the treatment of otorhinolaryngoiatric infections. Proc Int Cong Man Infect Amsterdam 1992; P273.
  • Frigerio D, Nastri A, Grossi E. Efficacy and safety of Augmentin in the treatment of infections in children. Proc 17th Int Congr Chemother Berlin 1991; A1255.
  • Fritz F, Fourie E, Pickard I, Reinach G. A randomized controlled study of oral roxithromycin and amoxycillin plus clavulanic acid in the treatment of patients with acute maxillary sinusitis. Proc 17th Int Congr Chemother Berlin 1991; A759.
  • Fujii R, Nishimura T. Pharmacokinetics and clinical studies on BRL25000 in the treatment of paediatrics infections. Proc 24th Interscience Conf Antimicrob Agents Chemother Washington 1984; 847.
  • Fujimura N, Yuasa K, Sasaki R, Kurokawa K. Basic and clinical studies on BRL25000 (clavulanic acid-amoxicillin) in urology. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 507–517.
  • Gaillat J, Jacquet JF, Janin A, Micoud M. Clinical trials in acute exacerbations of bronchitis with clavulanic acid-amoxycillin against josamycin. Pathol Biol 1987; 35 (5): 634–637.
  • Gallacher G, Erwin L, Scott PJW, Sleigh JD. Augmentin (amoxycillin-clavulanic acid) compared with amoxycillin alone in the treatment of urinary tract infections in the elderly. J Infect 1986; 12(3): 229–233.
  • Gan VN, Kusmiesz H, Shelton S, Nelson JD. Comparative evaluation of loracarbef and amoxicillin-clavulanate for acute otitis media. Antimicrob Agents Chemother 1991; 35(5): 967–971.
  • Gardembas-Pain M, Desablens B, Sensebe L, Lamy T, Ghandour C, Boasson M. Home treatment of febrile neutropenia: an empirical oral antibiotic regimen. Ann Oncol 1991; 2 (7): 485–487.
  • Garrel JP, Sonneck JM, Thabaut A, Leaute JB. Augmentin in the treatment of skin infections. Proc Eur Symp Augmentin Scheveningen 1982, Excerpta Med Curr Clin Pract Ser 1983; No. 4: 234–240.
  • Gehanno P, Simonet M, Moisy N. Utilisation d’une nouvelle resentation pediatrique (suspension) de l’association amoxicilline-acide clavulanique (AM-AC) dans les otites moyennes aigues du jeune enfant. Reun Interdiscip Chimiother Antiinfect 1987; Paris 3 December.
  • Gehanno P, Taillebe M, Denis P, et al. Short-course cefotaxime compared with five-day co-amoxyclav in acute otitis media in children. J Antimicrob Chemother 1990; 26 (Suppl A): 29–36.
  • Gerlach HL, Schaal KP, Walz C, Pape HD. Clinical efficacy of amoxicillin/clavulanic acid (AC) in severe odontogenic infections extending to face and neck. Proc 15th Int Congr Chemother Istanbul 1987; Abstr 962.
  • Germaud P, Benard Y, Brambilla C, Guerin JC, Nouvet G, Zuck P. Amoxycillin/clavulanate single-agent therapy as first-line treatment in community-acquired lung abscesses. Proc 2nd Biennial Conf Chemother Infect Dis Malig Montreux 1989; 8.
  • Golaescu M, Violescu M, Giuglea M, Dancu I. Our laboratory and clinical experience with Augmentin. Viata Med 1984; 31 (7): 327–331.
  • Goldstein EJC, Reinhardt JF, Murray PM, Finegold SM. Outpatient therapy of bite wounds – demographic data, bacteriology, and a prospective, randomized trial of amoxicillin/clavulanic acid versus penicillin and dicloxacillin. Int J Dermatol 1987; 26 (2): 123–127.
  • Goldstein FW, Goldstein FW, Kitzis MD, Acar JF. The protective role of clavulanic acid in urinary tract infections. Proc Eur Symp Augmentin Scheveningen 1982, Excerpta Med Curr Clin Pract Ser 1983; No 4: 178–182.
  • Goldstein FW, Kitzis MD, Acar JF. Effect of clavulanic acid and amoxycillin formulation against beta-lactamase producing Gram-negative bacteria in urinary tract infections. J Antimicrob Chemother 1979; 5: 705–709.
  • Goldstein FW, Kitzis MD, Malhuret C, Bourqelot P, Acar JF, Goldstein FW. Clinical evaluation of the formulation clavulanic acid plus amoxycillin in the treatment of urinary tract infections due to beta-lactamase-producing bacteria. Proc 19th Interscience Conf Antimicrob Agents Chemother, 11th Int Congr Chemother Boston 1979; 349–351.
  • Gooch WM, Congeni BL, Swenson E, Snellman LW. Effectiveness and safety of Augmentin in the management of pneumonia of infants and children. Curr Ther Res Clin Exp 1985; 37 (2): 178–183.
  • Graham VAL, Lowes JA, Shaw EJ, Davies RJ. An assessment of the value of Augmentin in the management of respiratory tract infections. Augmentin: Proc Int Symp, Montreux Switzerland, July 1981; Eds. Leigh DA and Robinson OPW, Excerpta Medica: 138–148.
  • Grange JD, Amiot X, Grange V, et al. Traitement de l’infection du liquide d’ascite du cirrhotique par amoxicilline-acide clavulanique. Ann Gastroenterol Hepatol 1991; 27 (2): 79–83.
  • Green-Thompson RW, Van Den Ende J, Vawda V, Kritzinger NA. A comparison of the efficacy of Augmentin and triple antibiotic therapy in gynaecological infections. Proc 2nd Biennial Conf Chemother Infect Dis Malig Montreux 1989; 55–56.
  • Gruer LD, Rodger RSC, Turney JH, Adu D, Michael J. Capd Peritonitis. Lancet 1983; 1 (8320): 349.
  • Gurwith MJ, Stein GE, Gurwith D. Prospective comparison of amoxycillin-clavulanic acid and cefaclor in treatment of uncomplicated urinary tract infections. Antimicrob Agents Chemother 1983; 24 (5): 716–719.
  • H’moud T, Mayaud C, et al. Comparative study of two therapeutic designs of amoxicillin-clavulanic acid(A-CA) in the treatment of community acquired pneumonia requiring hospitalization. Proc 16th Int Congr Chemother Jerusalem 1989; Abstr.
  • Hansen R. A double-blind efficacy and tolerance study of amoxycillin-clavulanic acid and cefaclor in the treatment of skin and skin structure infections. Postgrad Med 1984; Augmentin Symp Suppl: 239–243.
  • Hansrod D, Howalder R, Rozar GJ. A clinical and bacteriological evaluation of Augmentin: A new broad spectrum antibiotic in general practice. East Afr Med J 1983; 60 (11): 778–783.
  • Hart CA, Desmond AD, Percival A. Treatment of gentamicin-resistant klebsiella urinary tract infections with cephradine, Augmentin, cefuroxime and amikacin. J Antimicrob Chemother 1981; 8: 231–237.
  • Haruta T, Kuroki S, Okura K, Kobayashi Y. Bacteriological and clinical evaluation of BRL 25000 (clavulanic acid-amoxycillin) granules in the pediatric field. Jpn J Antibiot 1985; 38 (2): 359–372.
  • Hatano H, Hirayama N, Oki K. Studies On BRL2500 (clavulanic acid-amoxicillin) in the field of ophthalmology. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 598–604.
  • Havard CWH, Fernando A, Brumfitt W, Hamilton-Miller JMT. A pilot study of «Augmentin» in lower respiratory tract infections: Pharmacokinetic and clinical results. Br J Dis Chest 1982; 76 (3): 255–260.
  • Hebblethwaite EM, Brown GW, Cox DM. A comparison of the efficacy and safety of cefuroxime axetil and Augmentin in the treatment of upper respiratory tract infections. Drugs Exp Clin Res 1987; 13 (2): 91–94.
  • Henry-Suchet J, Douyeb B. Treatment of acute salpingitis with a combination of Augmentin and synthetic tetra-cycline or with Augmentin alone. Rev Fr Gynecol Obstet 1987; 82 (4): 281–284.
  • Hernandez A, Capdevila JA, Pigrau C, Andreu A, Bartolome R, Almirante B, Pahissa A, Martinez-Vanques JM. Comparative trial between oral amoxycillin-clavulanic acid or cefonicid in treatment of acute not complicated community-acquired pyelonephritis (PNF). Proc 7th Mediterr Congr Chemother Barcelona 1990; 20–25 May, Abstr 159.
  • Hirosaka K, Kamidono S, Ishigami J. Fundamental studies on BRL25000 (clavulanic acid-amoxicillin) in the urological field. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 496–506.
  • Hoshina H, Hirosawa H, Mikuni K, Ichihashi H. Fundamental and clinical studies on BRL 25000 (clavulanic acid-amoxycillin) granules in pediatric infections. Jpn J Antibiot 1985; 38 (2): 309–318.
  • Houang E, Colley N, Chapman M. Comparison of amoxycillin with clavulanate (Augmentin), with ampicillin and metronidazole, as the first line treatment for postoperative infections after gynaecological surgery. J Obstet Gynaecol Br Commonw 1987; 8 (2): 156–160.
  • Hugonot R, Hugonot L, Pappo M, Chiche D. Traitement ambulatoire par le cefuroxime-axetil des bronchites infectieuses du sujet de soixante ans ou plus: etude comparative avec l’association d’amoxicilline et d’acide clavulanique. Pathologie Biologie 1990; 38: 533–537.
  • Huizinga WKJ, Kritzinger NA, Bhamjee A. The value of adjuvant systemic antibiotic therapy in localised wound infections among hospital patients: A comparative study. J Infect 1986; 13 (1): 11–16.
  • Iravani A, Richard GA. Treatment of urinary tract infections with a combination of amoxicillin and clavulanic acid. Antimicrob Agents Chemother 1982; 22: 672–677.
  • Iravani A, Richard GA. Amoxicillin-clavulanic acid versus cefaclor in the treatment of urinary tract infections and their effects on the urogenital and rectal flora. Antimicrob Agents Chemother 1986; 29 (1): 107–111
  • Ito A, Shindo K, Fukushima K. Clinical studies on BRL25000 (clavulanic acid-amoxicillin) in the field of internal medicine. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 246–253.
  • Iwai N, Tanda Y, Shibata M, Mizoguchi F, Katayama M. Fundamental and clinical studies on BRL 25000 (clavulanic acid-amoxycillin) in the pediatric field. Jpn J Antibiot 1985; 38 (2): 342–358.
  • Jacobsson S, Rigner P, Von Sydow C, Bondesson G. Recurrent and penicillin V-resistant otitis media. A treatment study with amoxycillin-clavulanate and cefaclor. Acta Oto-Laryngol 1988; 106 (3–4): 171–177.
  • Jacqueme P, Magnan A, Lagier E, Chardon H, Poirier R. Utilisation de l’Augmentin dans les surinfections de bronchite chronique chez des patients n’ayant pas repondu a un premier traitement. Proc Ricai Paris 1989; 7 Dec: Abstr 18.
  • Jaffe AC, O’Brien CA, Reed MD, Blumer JL. Randomized comparative evaluation of Augmentin and cefaclor in pediatric skin and soft-tissue infections. Curr Ther Res Clin Exp 1985; 38 (1): 160–168.
  • Jaffe AC, O’Brien CA, Lemon E, Capretta TM, Aronoff SC, Blumer JL. Clinical experience with Augmentin in a pediatric outpatient setting. Postgrad Med 1984; Augmentin Symp Suppl: 199–211.
  • Jedlickova Z, Simkova M, Rubin A. Experiences with a combination of amoxicillin and clavulanic acid in vitro and in paediatric clinic. Proc 13th Int Congr Chemother Vienna 1983; 55: 93–98.
  • Jeffries MG, Rose AJ, Williams HN. An initial assessment of Augmentin for the treatment of paediatric infections in general practice. Br J Clin Pract 1983; 37 (2): 61–66.
  • Jensen T, Pedersen SS, Stafanger G, Hoiby N, Koch C, Bondesson G. Comparison of amoxycillin/clavulanate with amoxycillin in children and adults with chronic obstructive pulmonary disease and infection with Haemophilus influenzae. Scand J Infect Dis 1988; 20: 517–524.
  • Jibril HB, Ifere OAS, Odumah DU. An open, comparative evaluation of amoxycillin and amoxycillin plus clavulanic acid (Augmentin) in the treatment of bacterial pneumonia in children. Curr Med Res Opin 1989; 11 (9): 585–592.
  • Kafetzis DA, Carabinos CH, Kouppari G, Skandami V, Radiotis A, Apostolopoulos N. Cefprozil (CPZ) versus amoxicillin-clavulanate (AMC) in the treatment of acute otitis media (AOM) in children. Proc 17th Int Congr Chemother Berlin 1991; A1374.
  • Kaleida PH, Bluestone CD, Rockette HE, et al. Amoxycillin-clavulanate potassium compared with cefaclor for acute otitis media in infants and children. Pediatr Infect Dis J 1987; 6 (3): 265–271.
  • Kanazawa Y. Basic and clinical studies on BRL25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 262–268.
  • Kanematsu M, Sakai S, Hasegawa Y, Kato N, Kawada Y, Nishiura T. Beta-lactamase inhibitor in the treatment of urinary tract infection – Experimental and clinical studies on BRL25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 467–481.
  • Kapetanakis G, Hulla FW, Keratzopoulos D. A therapeutic study of Augmentin in a chest clinic. Proc Eur Symp Augmentin Scheveningen 1982. Excerpta Med Curr Clin Pract Ser 1983; No. 4: 291–297.
  • Kaplan EL, Johnson DR. Eradication of group A streptococci from the upper respiratory tract by amoxicillin with clavulanate after oral penicillin V treatment failure. J Pediatrics 1988; 113: 400–403.
  • Kaprio E, Haapaniemi J, Bondesson G. Clinical efficacy of amoxycillin/clavulanic acid and cefaclor in acute otitis media. Acta Oto-Laryngol 1988; 106 (449): 45–46.
  • Karachalios GN. Treatment of respiratory tract infections with a combination of amoxycillin and clavulanic acid. Int J Clin Pharmacol Ther Toxicol 1985; 23 (12): 647–649.
  • Karachalios GN, Georgiopoulos AN. Treatment of acute urinary tract infections with amoxycillin and clavulanic acid combination. IRCS Med Sci 1984; 12: 1042–1043.
  • Karachalios GN. Randomized comparative study of amoxycillin clavulanic acid and cotrimoxazole in the treatment of acute urinary tract infections in adults. Antimicrob Agents Chemother 1985; 28 (5): 693–694.
  • Kattamis C, Syriopoulou V, Papagregoriou-Theodoridou M, Moustrou-Antonellou G. Effectiveness of Augmentin in the treatment of urinary tract infections in children. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983; No. 4: 334–340.
  • Kattamis C, Syriopoulou V, Hadjiminas J, Tsivitanidou-Kacourou T. Effectiveness of intravenous Augmentin in the treatment of thalassemic patients with Yersinia enterocolitica infection. J Antimicrob Chemother 1984; 14: 303–305.
  • Kawada Y, Kanaematsu M, Nishiura T, et al. Comparative studies of BRL25000 (clavulanic acid-amoxicillin) and cefatrizine in complicated urinary tract infections. Chemotherapy (Tokyo) 1983; 31 (Suppl 2): 64–82.
  • Kawamura S, Sugita R, Fujimaki Y, Deguchi K. Fundamental and clinical studies on BRL 25000 (clavulanic acid-amoxicillin) in the field of otorhinolaryngology. Jpn J Antibiot 1983; 36: 500–508.
  • Key PR, Azadian BS, Evans BA. Augmentin compared with amoxycillin in treating uncomplicated gonorrhoea. Genitourinary Med 1985; 61 (3): 165–167.
  • Khan WN, Rodriguez WJ, Sait T, et al. Sultamicillin vs Augmentin in the treatment of acute otitis media (AOM). Proc 28th Interscience Conf Antimicrob Agents Chemother Los Angeles 1988; Abstr 330.
  • Kierszenbaum JS, Leite EV, Guimaraes PC, Marcelino MA, Cantaluppi ET. Clinical and laboratory study of BRL-25,000 in pediatric infections. Folha Med 1983; 86 (1–2): 71–77.
  • Kim JH, Kim SH, Hur H, Kim YT. Treatment of uncomplicated male gonococcal urethritis with clavulanate-potentiated amoxycillin. Korean J Dermatol 1987; 25(3): 343–350.
  • Kiosz D, Heilmann HD. Augmentin in the treatment of cystic fibrosis. Proc 6th Mediterr Congr Chemother Taormina 1988; Abstr 233: Page 139.
  • Kirei BR, Mhalu FS, Pallangyo PK, Seif SAB. The efficacy of Augmentin as a beta-lactam antibiotic in surgical and medical practice. East Afr Med J 1987; 64 (7): 499–503.
  • Kishida H, Kisaka Y, Matsubayashi S, et al. Clinical results of BRL25000 (clavulanic acid-amoxicillin) in the fields of obstetrics and gynecology. Jpn J Antibiot 1983; 36 (3): 487–499.
  • Klietmann W, Focht J, Nosner K, Kruger A, Machka K. Treatment of chronic tonsillitis with Augmentin (AUG) versus penicillin (PEN). Proc 17th Int Congr Chemother Berlin 1991; A1264.
  • Knobber D, Bergbreiter R. Zur Klinik der akuten epiglottitis erwachsener. Laryngo-Rhino-Otol 1991; 70: 695–697.
  • Kobayashi H, Takamura M, Takeda H, Kawai S. Clinical evaluation of BRL25000 (clavulanic acid-amoxicillin) in the RTI field. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 216–221.
  • Kollaritsch H, Pichler H, Jeschko E, Breyer S, Graninger W. Augmentin (amoxycillin/clavulanic acid formulation) in the treatmentof urinary tract infections. Proc 12th Int Congr Chemother Florence 1981. 1982: 780–782.
  • Kosmidis J, Stahakis C, Kotilis D, Daikos GK. Augmentin in the treatment of skin and soft tissue infections due to penicillin-resistant staphylococci. Proc 20th Interscience Conf Antimicrob Agents Chemother New Orleans 1980; Abstr 608.
  • Kosmidis J, Anyfantis A, Stathakis C, Mantopoulos K, Daikos GK. Augmentin (amoxycillin plus sodium clavulanate, a beta-lactamase inhibitor) is active in amoxycillin-resistant infections. Proc 19th Interscience Conf Antimicrob Agents Chemother, Boston 1979; 330–331.
  • Kumar B, Sharma VK, Sharma M. Clavulanic acid and amoxycillin in uncomplicated gonorrhoea. Indian J Dermatol Venereol Leprol 1989; 55: 294–296.
  • Kynast G. The use of Augmentin in general practice. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983; No. 4: 278–281.
  • Langan CE, Platt DJ, Guthrie AJ. A study of difficult respiratory infections in general practice. Scott Med J 1982; 27: S017–S020.
  • Lao LM, Lao MLM. A combination of amoxycillin and clavulanic acid in the treatment of acute male penicillin-resistant gonorrhoea in the Philippines. Augmentin: Proc Int Symp, Montreux Switzerland, July 1981 Eds. Leigh DA and Robinson OPW, Excerpta Medica: 222–226.
  • Larbre F, Thome J, et al. Etude de l’efficacite et de la tolerance d’une nouvelle formulation d’amoxicilline 100 mg -acide clavulanique 12.5 mg/ml par voie orale dans les infections urinaires du nourrisson. Proc 10th Interdise Meet Anti-Infect Chemother Paris 1990; Abstr 113/C8.
  • Latif AS, Sithole J, Bvumbe S, Gumbo B, Kawemba M, Summer RS. Trea ing gonococcal urethritis in men: Oral amoxycillin potentiated by clavulanate compared with intramuscular procaine penicillin. Br J Vener Dis 1984; 60 (1): 29–30.
  • Lawrence AG, Shanson DC. Single dose oral amoxycillin 3g with either 125mg or 250mg clavulanic acid to treat uncomplicated anogenital gonorrhoea. Genitourinary Med 1985; 61 (3): 168–171.
  • Le Clech G, Bourdiniere J. Efficacy of combined amoxycillin-clavulanic acid in the treatment of sinusitis in children and adults. A multicentre trial. Ann Oto-Laryngol 1987; 104: 147–150.
  • Leigh DA, Bradnock K, Marriner JM. Augmentin (amoxycillin and clavulanic acid) therapy in complicated infections due to beta-lactamase producing bacteria. J Antimicrob Chemother 1981; 7: 229–236.
  • Lenck LC, Fallouh B, Labouz F, Jacquetin B. Controle coelioscopique du traitement des salpingites. A propos de 40 observations. Rev Fr Gynaecol Obstet 1988; 83: 401–5.
  • Leng B. Augmentin in the treatment of urinary tract infections due to amoxycillin-resistant bacteria. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983; No. 4: 153–160.
  • Lerner SA, Lyon ES, Wald VC. The treatment of urinary tract infections with amoxycillin/potassium clavulanate (Augmentin) Postgrad Med 1984; Augmentin Symp Suppl: 225–228.
  • Leroy O, Beuscart C, Chidiac C, et al. Traitement des infections broncho-pulmonaires par l’association amoxycilline-acid clavulanique. Lille Med 1987; 27 (6): 302–305.
  • Levenstein JH. Efficacy and tolerability of amoxycillin/clavulanic acid combination in the treatment of common bacterial infections. S Afr Med J 1982; 62 (5): 16a–20a.
  • Levi D, Lemba P, Amery K. Treatment of postsurgical abdominal septic states: Comparative study of two antibiotic therapies. Pharmatherapeutica 1989; 5 (5): 355–363.
  • Lim KB, Rajan VS, Giam YC, Lui EO, Sng EH, Yeo KL. Two dose Augmentin treatment of acute gonorrhoea in men. Br J Vener Dis 1984; 60 (3): 161–163.
  • Lim KB, Thirumoorthy T, Lee CT, Sng EH, Tan T. Clinical experience in the use of clavulanic acid/penicillin regimens in the treatment of uncomplicated gonorrhoea. Ann Acad Med Singapore 1986; 15 (2): 258–261.
  • Lim KB, Thrumoorthy T, Lee CT, Sng EH, Tan T. Three regimens of procaine penicillin G, Augmentin, and probenecid compared for treating acute gonorrhoea in men. Genitourinary Med 1986; 62 (2): 82–85.
  • Lim VKE, Bakar R, Hussin Z. Single dose amoxycillin and clavulanic acid in the treatment of gonococcal urethritis in males. Med J Malays 1982; 37 (3): 235–238.
  • Lima MBC, Silva MA. Clinical and laboratory study with the BRL-25000 (amoxycillin/clavulanic acid). Folha Med 1984; 89 (1): 41–45.
  • Lippert D. A trial of orally adminstered Augmentin in the treatment of post-traumatic bone and joint infections. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983; No. 4; 241–251.
  • Lopes Filho O, Mimica I, Betti E, Burlamaqui JC, Takara C, Mimica LJ. Eficacia clinica e bacteriologica da associacao clavulanato de potassio + amoxicilina e do cefaclor em otite media aguda emcriancasc (Clinical and bacteriological efficacy of the association amoxicillin-clavulanate potassium compared with cefaclor for acute otitis media in children). Folha Med 1992; 104 (1–2): 39–42.
  • Lousbergh D, Jochems G, Everaert L, Puttemans M. Roxithromycin versus amoxycillin plus clavulanic acid in the treatment of respiratory tract infections. Proc 17th Int Congr Chemother Berlin 1991; A770.
  • Madsen PO, Dorflinger T, Frimodt-Moller P. Augmentin and cefaclor in treatment of complicated urinary tract infections. A comparative study. Postgrad Med 1984; Augmentin Symp Suppl: 191–193.
  • Maesen FPV, Davies BI, Baur C. Amoxycillin/clavulanate in acute purulent exacerbations of chronic bronchitis. J Antimicrob Chemother 1987; 19 (3): 373–383.
  • Magnusson I, Clark WB, Low SB, Maruniak J, Marks RG, Walker CB. Effect of non-surgical periodontal therapy combined with adjunctive antibiotics in subjects with refractory periodontal disease. (1) Clinical results. J Clin Periodontal 1989; 16: 647–653.
  • Maniatis T, Castellano M. Comparative evaluation of cefaclor versus amoxicillin/clavulanate potassium in the treatment of bacterial bronchitis. Curr Ther Res 1990; 48 (2): 308–312.
  • Marchant CD, Shurin PA, Johnson CE, et al. A randomized controlled trial of amoxicillin plus clavulanate compared with cefaclor for treatment of acute otitis media. J Pediatr 1986; 109 (5): 891–896.
  • Marino GT, De Moraes JL, De Oliveiro LS. Evaluation of BRL 25.000 — Clavulin — in paediatric patients. Arq Bras Med 1984; 58 (2): 131–137.
  • Martinelli R, Da Silva Lopes AA, De Oliveira MMMG, Rocha H. Amoxicillin-clavulanic acid in treatment of urinary tract infection due to Gram-negative bacteria resistant to penicillin. Antimicrob Agents Chemother 1981; 20 (6): 800–802.
  • Martinez JRI,Jellido MD,Granell JCSI, et al. Amoxicilina mas acido clavulanico en el tratamiento de las infecciones urinarias en pediatria (Amoxicillin and clavulanic acid in the treatment of paediatric urinary infections). An Esp Pediatr 1990; 32 (1): 53–57.
  • Martini H, Ziani F, Adjrad A. L’association amoxicilline/acide clavulanique comme antibiotherapie complementaire de la chirugie dans le traitement des osteomyelites hematogenes chronique. Med Mal Infect 1991; 21: 710–711.
  • Mashimo K. The results of clinical studies with BRL 25000 (Augmentin) in Japan. Augmentin: Proc Int Symp Montreux Switzerland, July 1981 Eds. Leigh DA and Robinson OPW, Excerpta Medica: 227–239.
  • Matsuda S. Augmentin treatment in obstetrics and gynaecology. Augmentin: Proc Int Symp, Montreux Switzerland, July 1981 Eds. Leigh DA and Robinson OPW, Excerpta Medica: 179–191.
  • Matsumoto K, Shishido H, Takahashi A, et al. Clinical evaluation of BRL25000, combination of amoxicillin and clavulanic acid in respiratory tract infection. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 349–357.
  • Matsuoka K, Konno S, Eto K. Clinical evaluation of BRL25000 (clavulanic acid amoxicillin) in urinary tract infections. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 517–523.
  • Mayer HO, Jeschek H, Kowatsch A. Augmentin in the the treatment of urinary tract infection in pregnant women and pelvic inflammatory disease. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983; No. 4: 207–217.
  • Mayhew SR. A comparison of cefuroxime axetil and amoxycillin/clavulanic acid in the treatment of lower respiratory tract infection in general practice. R Soc Med Int Congr Symp Ser 1987; No. 124: 45–52.
  • McCarty JM, Froehlich HF, Renteria A, Linn LS, Farlow D, Therasse D. Randomized trial of LY163892, a new oral carbacephem antibiotic, vs amoxicillin/clavulanate potassium in the treatment of bronchitis. Proc Eur Congr Clin Microbiol Nice 1989; Abstr 130.
  • McGhie D, Kerfoot P, Talbot DJ. A comparative study of Miraxid (pivmecillinam plus pivampicillin) and Augmentin (amoxycillin-clavulanic acid) in the treatment of lower respiratory tract infections in general practice. J Int Med Res 1986; 14: 254–260.
  • Mehta AP, Phutane L, Patel MH, Rupwate RU, Kamat SR. Comparative study of amoxycillin and amoxycillin-/clavulanic acid in lower respiratory infections. J Assoc Physicians India 1991; 39 (3): 251–253.
  • Mehtar S, Ball AP. Intravenous Augmentin in bacteraemia and severe invasive polymicrobial sepsis. J Antimicrob Chemother 1985; 15 (6): 765–771.
  • Mehtar S. Respiratory tract infections caused by beta-lactamase producing organisms treated with Augmentin. Scott Med J 1982; 27: S24–S27.
  • Mehtar S. Serious thoracic and abdominal infections treated with intravenous Augmentin. Proc 3rd Mediterr Congr Chemother Dubrovnik. Chemioterapia 1984; 1 (4).
  • Michel JP, Sauvage P, Denis F, Babied G, Berardi-Grassais L, Richardin F. Utilisation de l’Augmentin en traitment de premiere intention et en monotherapie dans les infections basses du sujet age vivant en collectivite: Etude clinique et bilan bacteriologique. Med Mal Infect 1988; (Suppl 5): 389.
  • Micillo E, Dericoloso A, Tranchese D, Cione P. Clavulanic acid-shielded amoxicillin in the treatment of acute and chronic infective diseases of the pulmonary system. Arch Monaldi 1987; 42 (6): 535–549.
  • Miki F, Takamatsu K, Kohno M, et al. Comparison of BRL25000 (clavulanic acid-amoxicillin) and amoxicillin in the treatment of chronic respiratory tract infections. Chemotherapy (Tokyo) 1983; 31 (Suppl 2): 1–43.
  • Miki F, Takamatsu K, Kohno M, Beppu K, Kubo K. Clinical studies on BRL25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 292–295.
  • Millard G. Further treatment with Augmentin in the treatment of skin infections. Scott Med J 1982; 27: S35–S38.
  • Millard LG, Abbas AMA. The treatment of skin and soft-tissue infections with Augmentin. Proc 1st Symp Augmentin Excerpta Med Int Cong Ser Excerpta Med Int Cong Ser 1980; 231–236.
  • Minamitani M, Hachimori K, Kaneda K. Basic and clinical studies of BRL25000 (clavulanic acid – amoxycillin) granules in the field of pediatrics. Jpn J Antibiot 1985; 38 (2): 415–422.
  • Mira E, Messa A, Garotta F, Pamarana F. Amoxicillin + clavulanic acid in the treatment of E.N.T. infections: Results of an Italian multicentre study. Proc 17th Int Congr Chemother Berlin 1991; A1026.
  • Miyachi Y, Ueda S, Hayakawa F, Nakashima T, Hakamada S, Kuno K. Fundamental and clinical studies on BRL 25000 (clavulanic acid amoxycillin) granules in the pediatric field. Jpn J Antibiot 1985; 38 (2): 423–430.
  • Mogavero S, Accomando A, Benigno V. Treatment of infectious bronchopneumopathies in children with amoxycillin and clavulanic acid. Pediatr Med Chir 1988; 10 (5): 511–516.
  • Morales WJ, Collins EM, Angel JL, Knuppel RA. Short course of antibiotic therapy in treatment of postpartum endomyometritis. Am J Obstet Gynaecol 1989; 161: 568–572.
  • Moreo G, Sardi C, Braschi R, Nani M, Remotti G. Comparison of an antibiotic combination (amoxicillin + clavulanic acid) and cefaclor in the treatment of acute or flareups of chronic bronchopneumopathies. Clin Ter 1988; 126 (6): 411–416.
  • Motohiro T, Tanaka K, Koga T. Basic and clinical trials of BRL25000 (clavulanic acid-amoxycillin) granules in the field of paediatrics. Jpn J Antibiot 1985; 38 (2): 481–506.
  • Motohiro T, Tanaka K, Koga T. Clinical trial of BRL25000 (clavulanic acid-amoxicillin) granules on skin and soft tissue infections in the field of pediatrics. Jpn J Antibiot 1985; 38 (2): 507–537.
  • Motta P, Catania A, Blasi F, Zanussi C. Use of amoxycillin-clavulanic acid (Augmentin) in uncomplicated lower urinary tract infections (UTI) caused by aminopenicillin-resistant bacteria. Proc 7th Mediterr Congr Chemother Barcelona 1990; 20–25 May, Abstr 154.
  • Mouton Y, Beuscart C, Leroy O, Ajana F, Charrel J. Evaluation de la ciprofloxacine versus amoxicilline plus acide clavulanique ou erythromycine pour le traitement empirique des pneumonies communautaires. Pathol Biol 1991; 39 (1): 34–37.
  • Mouzinho A, Abrantes M, Pinto F, Marques Pinto L. Treatment of respiratory tract infections caused by Haemophilus influenzae with Augmentin (amoxycillin/clavulanic acid): Prospective trial. J Drug Dev 1989; 2 (Suppl 1): 79–82.
  • Munday PE, Bingham JS, Ison CA, Erdman YJ, Harris JRW, Easmon CSF. Treatment of gonorrhea with clavulanate-potentiated amoxycillin (Augmentin). Sex Trans Dis 1985; 12 (3): 163–165.
  • Music E, Kumelj M, Prlja D, Paulin A, Potokar T. Uporedenje amoksicilina i amoksiklava u terapiji respiracionih infekcija (RI) (Comparison of amoxicillin and amoxclav in the treatment of respiratory tract infections). Plucne Boles Tuberk 1989; 41 (3–4): 187–192.
  • Nagamatsu I, Horiguchi S. Clinical study of BRL 25000 (clavulanic acid-amoxycillin) granules in pediatric infections. Jpn J Antibiot 1985; 38 (2): 287–295.
  • Nagata K, Yokoyama M. Clinical experience with BRL 25000 (clavulanic acid-amoxycillin) granules in pediatric infections. Jpn J Antibiot 1985; 38 (2): 263–268.
  • Nakamuta S, Momose S, Kumazawa J, Emoto K, Hara S, Tsunodo K. Clinical evaluation of BRL25000 (clavulanic acid-amoxicillin) on urinary tract infections. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 513–516.
  • Nakano M, Kanzaki R, Hayakawa M, et al. Clinical studies on BRL25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 184–190.
  • Nakauchi K, Akima S. Clinical evaluation for BRL25000 (clavulanic acid-amoxicillin) on the complicated urinary tract infection in aged patients. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 418–423.
  • Nakayama I. BRL 25000 – Augmentin: Clinical experience in the treatment of surgical and dermatological infections. Augmentin: Proc Int Symp, Montreux Switzerland, July 1981 Eds. Leigh DA and Robinson OPW, Excerpta Medica: 165–178.
  • Nakazawa S, Sato H, Narita A. Fundamental and clinical studies on BRL 25000 (clavulanic acid-amoxycillin) granules in the pediatric field. Jpn J Antibiot 1985; 38 (2): 296–308.
  • Ndinya-Achola Jo, Nsanze H, Karasira P, et al. Three day oral course of Augmentin to treat chancroid. Genitourinary Med 1986; 62 (3): 202–204.
  • Nishimura T, Tabuki K, Takashima T, Takagi M. Laboratory and clinical studies of BRL25000 (clavulanic acid-amoxicillin) granules in the pediatric field. Jpn J Antibiot 1985; 38 (2): 431–440.
  • Nishiura T. Efficacy of Augmentin (BRL 25000) in urinary tract infections. Augmentin: Proc Int Symp Montreux Switzerland, July 1981 Eds. Leigh DA and Robinson OPW, Excerpta Medica: 65–77.
  • O’Donovan C, Rudd R, O’Neill S, et al. Augmentin (intravenous then oral) compared with cefuroxime followed by cephalexin for chest infections in hospitalised patients. Br J Clin Pract 1987; 41 (12): 1044–1052.
  • O’Dowd TC, Ribeiro CD, Smail JE, Menday AP, Howells CHL. A comparative trial of pivmecillinam/pivampicillin and amoxycillin/clavulanate in the therapy of urinary tract infection in a general practice population. Curr Med Res Opin 1984; 9: 310–315.
  • Obwegeser J, Kunz J, Wust J, Schar G, Steiner R, Buchi W. Clinical efficacy of amoxycillin/clavulanate in laparoscopically confirmed salpingitis. J Antimicrob Chemother 1989; 24 (Suppl.B): 165–176.
  • Odio CM, Kusmiesz H, Shelton S, Nelson JD. Comparative treatment trial of Augmentin versus cefaclor for acute otitis media with effusion. Pediatrics 1985; 75 (5): 819–826.
  • Ohkawa M, Shoda R, Sugata T, et al. Clinical evaluation of BRL25000 (clavulanic acid-amoxicillin) in urinary tract infections. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 482–495.
  • Ohkawa M, Kuroda K A comparative study of BRL 25000 – Augmentin – and amoxycillin in complicated urinary tract infections. Augmentin: Proc Int Symp Montreux Switzerland, July 1981 Eds. Leigh DA and Robinson OPW, Excerpta Medica: 86–95.
  • Okada K, Murakami Y, Kinoshita H, Kawamura N, Ohkoshi M. Fundamental and clinical Studies on BRL25000 (clavulanic acid-amoxicillin) in the field of urology. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 443–456.
  • Okazaki T, Machida T, Onodera S, Mitsui K, Suzono I. Fundamental and clinical studies on BRL25000 (clavulanic acid-amoxicillin) in gonorrhoeal urethritis. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 413–417.
  • Okubo H, Okamoto Y, Ueda Y, Maehara K, Mase K, Yonezu S. Basic and clinical studies On BRL25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 273–291.
  • Oldini C, Messa A, Pamparana F, Garotta F. Effectiveness and tolerability of amoxicillin + clavulanic acid in the treatment of ear infections. Proc 17th Int Congr Chemother Berlin 1991; A1027.
  • Ooishi M, Nagai S. Laboratory and clinical experiments in the ophthalmic application of BRL25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 605–611.
  • Osato K, Tsugami H, Harada K, Maruyama J. Incidence of gonorrhoea due to penicillinase producing Neisseria gonorrhoeae in Japan 1981–3 and treatment using a new antibiotic combination, BRL25000 (amoxycillin and clavulanic acid Genitourinary Med 1986; 62 (3): 158–162.
  • Osoba AO, Oyelese AO, Ashiru JP, Ekweozor CC, Ochei J. Single dose treatment of gonococcal urethritis with Augmentin in Ibadan. Proc Int Conjoint Sex Trans Dis Meeting Montreal 1984.
  • Osoba AO, Ocunbanjo BO, Adeyemi-Doro FAB, Rotowa NA, Ochei J. Single dose therapy of gonorrhoea with Augmentin plus probenecid. Afr J Sex Trans Dis 1986; Feb: 11–13.
  • Palcoux JB, Raynaud EJ, Borderon JC, et al. A clinical trial of the clavulanic acid amoxicillin combination in childhood urinary tract infection. Ann Pediatr 1986; 33 (8): 761–763.
  • Palermo B, Rizza S, Pistorio MP, Crimi N, Maccarrone C, Mistretta A. Therapy of infective respiratory diseases with a shielded beta-lactam antibiotic (amoxicillin and clavulanic acid). Arch Monaldi 1987; 42 (6): 519–533.
  • Pariente R. Results of a comparative clinical trial of erythromycin versus the amoxycillin-clavulanic acid combination in acute bronchial superinfections in patients with chronic respiratory failure. Sem Hop 1987; 63 (20): 1653–1657.
  • Pecco P, Torta L, Negro F, Pavesio D. Amoxicillin and clavulanic acid suspension for children in the treatment of bronchopulmonary infections. Pediatr Med Chir 1989; 11: 65–70.
  • Pedler SJ, Bint AJ. Comparative study of amoxycillin-clavulanic acid and cephalexin in the treatment of bacteruria during pregnancy. Antimicrob Agents Chemother 1985; 27 (4): 508–510.
  • Penn RL, Manocha KL, Burford JG, George RB. Prospective comparison of Augmentin and cefaclor as therapy for lower respiratory infections. Postgrad Med 1984; Augmentin Symp Suppl: 251–255.
  • Periti P, Novelli A, Schildwachter G, Schmidt-Gayk H, Ryo Y, Zuck P. Efficacy and tolerance of cefpodoxime proxetil compared with co-amoxiclav in the treatment of exacerbations of chronic bronchitis. J Antimicrob Chemother 1990; 26 (Suppl E): 63–69.
  • Peyramond D, Abenhaim N, Chiche D. Etude du traitement antibiotique des infections respiratoires acquises en ville: Cefuroxime axetil vs amoxicilline/acide clavulanique (Community acquired respiratory infections: Cefuroxime axetil versus amoxicilline/clavulanic acid). Med Mal Infect 1991; 21 (Spec. Iss.): 98–102.
  • Peyrille F, Carriere JP, Dalous A. Oral treatment with a combination of amoxicillin-clavulanic acid in 41 children. Rev Pediatr 1986; 22 (8): 347–352.
  • Pichichero M, Aronovitz GH, Gooch WM, et al. Comparison of cefuroxime-axetil, cefaclor and amoxicillin-clavulanate potassium suspensions in acute otitis media in infants and children. Southern Med J 1990; 83: 1174–1177.
  • Pien FD. Double-blind comparative study of two dosage regimens of cefaclor and amoxicillin-clavulanic acid in the outpatient treatment of soft tissue infection. Antimicrob Agents Chemother 1983; 24 (6): 856–859.
  • Pines A, Raafat H, Khorasani MH, Jabbar NA, Sharma JC. Experience with amoxycillin plus potassium clavulanate in lower respiratory tract infections. Proc 1st Symp Augmentin Excerpta Med Int Cong Ser 1980: 277–282.
  • Pitt WR. Augmentin therapy in childhood urinary tract infection. Aust Paediatr J 1986; 22 (3); 254.
  • Ploechl E, Pirko P, Huber EG. Clinical experience with oral and injectable Augmentin in the treatment of paediatric patients. Proc 9th Int Congr Infect Parasit Dis Munich 1986: Abstr 1403.
  • Ploechl E, Huber EG. Clinical experience with intravenous Augmentin in the treatment of paediatric infections. J Int Med Res 1986; 14 (3): 153–157.
  • Plouffe JF. Augmentin treatment of lower respiratory tract infections. Postgrad Med 1984; Augmentin Symp Suppl: 183–185.
  • Prat V, Horcickova M, Hatala M, Liska M, Matousovic K. The combination of amoxycillin and clavulanic acid in urinary tract infections (UTI) caused by bacterial strains producing beta-lactamase. Proc 13th Int Congr Chemother Vienna 1983. 1983 97: 52–58.
  • Price JD. Augmentin. a review of paediatric clinical evaluations in the UK including a survey of bacteriological isolates and clinical efficacy and safety. Proc 22nd Interscience Conf Antimicrob Agents Chemother Miami 1982. 1982: Abstr 310.
  • Principi N, Vigano A, Dalla Villa A, Reali E. Therapy of urinary tract infections (UTIs) in children with amoxycillin plus clavulanic acid. Proc 6th Mediterr Congr Chemother Taormina 1988: Abstr 37.
  • Principi N, Marchisio P, Tornaghi R, Onorato J, Massironi E, Picco P. Acute otitis media in human immuno-deficiency virus-infected children. Pediatrics 1991; 88 (3): 566–571.
  • Quinn EL, Cardenas JV, Pohlod D, et al. Treatment of skin and soft tissue infections with amoxycillin-clavulanic acid or cefaclor. Postgrad Med 1984; Augmentin Symp Suppl: 97–104.
  • Rademaker CMA, Sips AP, Beumer HM, et al. A double-blind comparison of low-dose ofloxacin and amoxycillin/clavulanic acid in acute exacerbations of chronic bronchitis. J Antimicrob Chemother 1990; 26 (Suppl D): 75–81.
  • Rampulla C, Fracchia C, Messa A, Garotta F, Pamparana F. Amoxicillin plus clavulanic acid (Clavulin) in exacerbations of COPD: Preliminary findings of a multicentretrial. Proc 17th Int Congr Chemother Berlin 1991: Abstr 1019.
  • Raz R, Rottensterich E, Boger S, Potasman I, Comparison of single-dose administration and 3-day course of amoxicillin with those of clavulanic acid for treatment of uncomplicated urinary-tract infection in women. Antimicrob Agents Chemother 1991; 35 (8): 1688–1690.
  • Raz R, Halevy R, Antonelli Y, Keness J. The use of Augmentin in hospitalized and ambulatory children. Chemotherapia 1989; 1 (2): 110–112.
  • Rees T, Saul S, Tehan S. Augmentin in the treatment of acute otitis media: A comparative study. Proc 7th Mediterr Congr Chemother Barcelona 1990; 20–25 May: Abstr: 158.
  • Reeves DS, Elliot PJ, Holt HA, Chapman ST, Mojaddedi Z. A clinical trial of Augmentin in urinary tract infections. Proc 1st Symp Augmentin Excerpta Med Int Cong Ser 1980: 138–144.
  • Reiner E. Augmentin of urinary tract infections in patients with neurogenic disorders of micturition secondary to spinal injury. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983; No. 4: 169–178.
  • Reme JM, Anguill C, Boulogne M, et al. Comparison between 2 designs of amoxycillin-clavulanic acid (A-CA) in the treatment of acute pelvic inflammatory disease with coelioscopy. Proc 16th Int Congr Chemother Jerusalem 1989: Abstr.
  • Renton RL, Murphy O’Connor JC, Westlake DM. Comparison of bacampicillin (Ambaxin) and Augmentin in the treatment of acute bronchitis in general practice. Clin Trials J 1984; 2184: 207–214.
  • Risser WL, Kaplan SL, Mason EO, Listernick R, Yogev R, Pickering LK. Treatment of soft tissue infections in children with amoxicillin-clavulanic acid combination or cefaclor. Curr Ther Res Clin Exp 1985; 37 (4): 747–753.
  • Roydhouse N. Antibiotic treatment of otitis media with effusion. NZ Med J 1991; 104: 380–382.
  • Ruberto U, D’Eufemia P, Martino F, Giardini O. Amoxycillin and clavulanic acid in the treatment of urinary tract infections in children. J Int Med Res 1989; 17 (2): 168–171.
  • Ruiz Speare JO. Treatment of respiratory, urinary, or soft tissue infections with Augmentin. Invest Med Int 1983; 10 (3): 254–259.
  • Ruiz Speare JO. Treatment of respiratory infections with Augmentin given every 12 hours. Invest Med Int 1983; 10 (3): 251–253.
  • Sabbour MS, Osman LM. Experience with antimicrobial combinations in urinary tract infections. Drugs Exp Clin Res 1988; 14 (1): 45–51.
  • Saenz Aguirre C. Evaluation of Augmentin in the treatment of bacterial infections of children. Invest Med Int 1983; 10 (2): 155–159.
  • Saenz Aguirre C. Evaluation of Augmentin in the treatment of bacterial infections in paediatric patients. Invest Med Int 1983; 10 (1): 43–48.
  • Saito A, Kato Y, Ishikawa K, et al. Basic and clinical studies of BRL25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 125–143.
  • Sakai K, Fujimoto M, Ueda T, et al. Clinical trials of BRL25000 (clavulanic acid-amoxicillin) on infectious diseases of the skin and soft tissues. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 387–396.
  • Sakai S, Kumamoto Y, Nishio A, Maruta H, Hasegawa M. Basic and clinical studies on BRL25000 (clavulanic acid-amoxicillin), Treatment of urinary tract infections. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 402–412.
  • Saroglou G, Paniara-Volika O, Sima A, et al. Amoxycillin and clavulanic acid combination: Clinical and laboratory evaluation in pulmonary infections. Clin Therap 1982; 4 (6): 442–449.
  • Sato Y, Iwata S, Akita H, et al. Fundamental and clinical studies on BRL 25000 (clavulanic acid-amoxycillin) granules in the pediatric field. Jpn J Antibiot 1985; 38: 327–341.
  • Sawada H, Miura K, Kinoshita R, et al. Clinical studies on BRL25000 (clavulanic acid-amoxicillin) in the field of internal medicine. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 269–272.
  • Sawaki M, Nakano H, Tsujimura M, et al. Clinical evaluation of BRL25000 (clavulanic acid-amoxicillin) in respiratory tract infections. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 298–303.
  • Schaad UB, Pfenninger J, Wedgwood-Krucko J. Sequential intravenous-oral amoxycillin/clavulanate (Augmentin) therapy in paediatric hospital practice. J Antimicrob Chemother 1987; 19 (3): 385–391.
  • Schift R, Van Ulsen J, Ansink-Schipper MC, et al. Comparison of oral treatment of uncomplicated urogenital and rectal gonorrhoea with cefuroxime axetil ester or clavulanic acid-potentiated amoxycillin (Augmentin). Genitourinary Med 1986; 62 (5): 313–317.
  • Schmidt EW, Zimmermann I, Ritzerfeld W, Voss E, Ulmer WT. Controlled prospective study of oral amoxycillin-/clavulanate vs ciprofloxacin in acute exacerbations of chronic bronchitis. J Antimicrob Chemother 1989; 24 (Suppl.B): 185–193.
  • Schmitt M, Bondonny Jm, Delmas P, et al. Antibiotic therapy of perforated appendicitis in children: A comparison of amoxycillin/clavulanate with a combination of benzylpenicillin, netilmicin and metronidazole. J Antimicrob Chemother 1989; 24 (Suppl.B): 157–163.
  • Schutz Von W. Behandlung unkomplizierter harnwegsinfektionen. Wirksamkeit und vertraglichkeit von sultamicillin gegenuber amoxicillin/clavulansaure. Fortschr Med 1990; 18: 365–368.
  • Schwartz RH, Mclinn S, Camacho A, Macloughlin G, Ossi M. Cefuroxime axetil suspension versus amoxicillin/clavulanate suspension in the treatment of acute otitis media in children. Proc 17th Int Congr Chemother Berlin 1991: A1371.
  • Schwigon CD. Treatment of nosocomial respiratory tract infections with oral Augmentin. Proc 13th Int Congr Chemother Vienna 1983; 22: 56–57.
  • Schwigon CD, Barckow D, Gotz D, Hopfenmuller G. Comparactive clinical study of Augmentan and ciprofloxacin in the treatmentof respiratory infection in hospitalized patients. Proc 16th Int Congr Chemother Jerusalem 1989: Abstr.
  • Seidenfeld JJ. A double-blind trial of amoxicillin and clavulanic acid versus cefaclor in adult patients with lower respiratory tract infection. Postgrad Med 1984; Augmentin Symp Suppl: 177–181.
  • Sekita T, Takahashi H, Kobayashi Y, Fujimori I. Clinical study on BRL25000, a combination drug of amoxicillin and clavulanic acid. Chemotherapy (Tokyo) 1982; 30 (Suppl): 239–245.
  • Sevieri GF. Studio sull’efficacia e la tollerabilita del cefaclor e della amoxicillina-acido clavulanico nel trattamento delle infezioni del tratto respiratorio inferiore (Efficacy and tolerability of cefaclor and amino clavulanic acid in the treatment of lower respiratory tract infections). Minerva Pneumol 1991; 30 (2): 95–97.
  • Shalit I, Dagan R, Einhorn M, et al. Prospective, randomized, comparative study of amoxicillin-clavulanate versus ceftriaxone for the treatment of periorbital cellulitis in pediatric patients. Proc 7th Mediterr Congr Chemother Barcelona 1990; 20–25 May: Abstr 90.
  • Shanks N, Maclin J, Coles S. Comparison of oral erythromycin ethylsuccinate and clavulanate-potentiated amoxicillin in the treatment of acute respiratory tract infections. Clin Ther 1989; 11 (6): 812–819.
  • Shigemi K, Kaoru S, Isao F, et al. Studies on the usefulness and safety of Augmentin (clavulanic acid amoxicillin) in urological field. Med Consult New Remedies 1989; 26 (10): 65–74.
  • Shinozaki T, Meguro H, Fujii R, Mashiko Z, Okamoto Y, Arimasu O. Fundamental and clinical evaluation of the BRL 25000 (Amoxycillin-clavulanic acid) granules in the pediatric field. Jpn J Antibiot 1985; 38 (2): 269–285.
  • Snavely SR, Harms JL, Hinthorn DR, Liu C. Efficacy of amoxycillin-potassium clavulanate in the treatment of urinary tract infections. Postgrad Med 1984; Augmentin Symp Suppl: 213–217.
  • Soejima R, Niki Y, Kawanishi M, Matsushima T, Okimoto T, Nakahama T. Fundamental and clinical studies on BRL25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 304–313.
  • Solbiati M, Concia E, Bassetti D. The role of Augmentin in the treatment of upper and lower respiratory tract infections in children. Proc 6th Mediterr Congr Chemother Taormina 1988; Page 18: Abstr 38.
  • Spector SL, Camacho AE, Corbo R, et al. Comparison of the efficacy and safety of cefuroxime axetil and amoxycillin clavulanate in the treatment of patients with acute bacterial maxillary sinusitis. J Allergy Clin Immunol 1992; 782.
  • Stahl JP, Pappo M. A multicenter randomized trial of cefuroxime-axetil versus amoxicillin with clavulanic acid in community-acquired ENT and lower respiratory tract infections. Sem Hop 1989; 65 (5): 247–251.
  • Stamboulian D, Sarachian B, Arguello E, Belforte B. Evaluation of amoxicillin with and without BRL 14151 in the treatment of urinary tract infections. Proc 19th Interscience Conf Antimicrob Agents Chemother, Boston 1979: 338–340.
  • Starnes WL, Szechinski J, Behal FJ. Human liver alanine aminopeptidase: A kinin converting enzyme sensitive to beta-lactam antibiotics. Eur J Biochem 1982; 124 (2): 363–370.
  • Stein GE, Patterson MJ, Gurwith D, Van Der Laan BA, Gurwith MJ. Amoxycillin/clavulanic acid therapy of acute urinary tract infection. Curr Ther Res Clin Exp 1982; 32 (4): 617–623.
  • Stenstrom C, Lundgren K, Ingvarsson L, Bertilson SO. Amoxycillin/clavulanate versus amoxycillin in recurrent otitis media and therapeutic failure in children. Acta Otolaryngol (Stockh) 1991; 111: 120–129.
  • Stevens JD, Abbas AMA. Therapeutic study of Augmentin in respiratory tract infections. Proc 1st Symp Augmentin 1980; 287–292.
  • Stewart JSS. Augmentin versus cephradine and metronidazole in the treatment of serious infections – A comparative clinical study. Proc 7th Int Symp Future Trends Chemother 1986: Abstr.
  • Stockley RA, Dragicevic P, Burnett D, Hill SL Role of beta-lactamases in the response of pulmonary infections to amoxycillin/clavulanate. J Antimicrob Chemother 1989; 24 (Suppl.B): 73–81.
  • Sunakawa K, Ishizuka Y. Basic and clinical studies on BRL 25000 (clavulanic acid-amoxycillin) granules in the pediatric field. Jpn J Antibiot 1985; 38 (2): 319–326.
  • Suputtamongkol Y, Dance DAB, Chaowagul W, Wattanagoon Y, Wuthiekanun V, White NJ. Amoxycillin-clavulanic acid treatment of melioidosis. Trans R Soc Trop Med Hyg 1991; 85: 672–675.
  • Suwaki M, Ikeda M, Kashiwa N, Nohara N. Fundamental and clinical studies on BRL25000 (clavulanic acid-amoxicillin) in the field of dermatology. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 587–593.
  • Suzuki K. Laboratory and clinical studies on BRL25000 (clavulanic acid-amoxicillin) in the urinary tract infection. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 424-442.
  • Symonds J, Biswas AK. Amoxycillin, Augmentin, and metronidazole in bacterial vaginosis associated with Gardnerella vaginalis. Genitourinary Med 1986; 62 (2): 136.
  • Takase Z, Shirafuji H, Uchida M. Clinical and laboratory studies on BRL25000 (clavulanic acid-amoxicillin)in the field of obstetrics and gynecology. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 579–586.
  • Takebe K, Kumasaka Y, Nakahata H, et al. Fundamental and clinical studies on BRL25000 (clavulanic acid-amoxicillin) in internal field. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 152–167.
  • Takebe K. The evaluation of Augmentin treatment in respiratory tract infections. Augmentin: Proc Int Symp, Montreux Switzerland, July 1981 Eds. Leigh DA and Robinson OPW, Excerpta Medica: 125–137.
  • Tan JS, File TM. Double blind efficacy and safety study of Augmentin versus cefaclor in the treatment of lower respiratory tract infection. Postgrad Med 1984; Augmentin Symp Suppl: 129–131.
  • Tan TH, Tay L, Yeo M, Feng PH. Augmentin (amoxycillin and clavulanic acid) in the treatment of urinary tract infections and skin and soft tissue infections. Singapore Med J 1983; 24 (5): 299–302.
  • Tanz RR, Shulman ST, Sroka PA, Yogev R. Influence of beta-lactamase-producing flora on recovery of Group A streptococci following treatment of acute pharyngitis. Am J Dis Child 1989; 143 (4): 419.
  • Tassler H, et al. Fleroxacin (FL) versus amoxicillin clavulanate potassium (AMX/CP) in the therapy of skin and soft tissue infections. Proc 17th Int Congr Chemother Berlin 1991: A1455.
  • Tatsis G, Veslemes M, Hadjistavrou C, Votsiou A, Jordanoglou J. Treatment of lower respiratory tract infections with amoxycillin-clavulanic acid (A-CA) in adults. Proc 7th Mediterr Congr Chemother Barcelona 1990; 20–25 May: Abstr 90.
  • Tazi-Lakhsassi L, Abid A, Sehlane M. Tolerance de l’association amoxicilline -acide clavulanique. J Int Med Res 1986; 14 (6): 158.
  • Thomassin J-M, Pech A. Interet de l’association acide clavulanique-amoxicilline dans le traitement de l’otite aigue de l’enfant a propos d’une etude multicentrique hospitalière portant sur 134 observations. J Med Lyon 1986; 1420.
  • Thomsen J, Sederberg-Olsen J, Balle V, Vejlsgaard R, Stangerup S-E, Bondesson G. Antibiotic treatment of children with secretory otitis media. Arch Otolaryngol Head Neck Surg 1989; 115: 447–451.
  • Thornley PE, Aitken JM, Nichol GM, Slevin NJ. Amoxycillin-clavulanic acid combination in bronchopulmonary infection due to beta-lactamase-producing Branhamella catarrhalis – Preliminary report. Drugs 1986; 31 (Suppl 3): 113–114.
  • Tio D, De Koning GAJ, Ansink MC, Coutinho RA. Augmentin in the treatment of gonorrhoea caused by penicillinase-producing gonococci. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983; No. 4: 218–223.
  • Tison E, Marpeau L, Pigne A, Tessier F, Barrat J. The treatment of non-chlamydial acute salpingitis. A study into the efficacy and tolerance of a single-therapy antibiotic, namely Augmentin. J Gynecol Obstet Biol Reprod 1988; 17 (4): 513–519.
  • Tolkoff-Rubin NE, Weber D, Kelly M, Wilkinson R, Rubin RH. The use of a fixed drug combination of amoxycillin and clavulanic acid (Augmentin) in the treatment of urinary tract infection: A preliminary report. Augmentin: Proc Int Symp, Montreux Switzerland, July 1981 Eds. Leigh DA and Robinson OPW, Excerpta Medica: 57–64.
  • Toporovski J, Steffens L, Noack M, Kranz A, Burdeska A, Kissling M. Effectiveness of cefetamet pivoxil in the treatment of pyelonephritis in children. J Int Med Res 1992; 20 (1): 87–93.
  • Toyonaga Y, Kurosu Y, Sugita M, Nakamura H, Takahashi T, Hori M. Fundamental and clinical studies on BRL 25000 (clavulanic acid-amoxycillin) granules in the pediatric field. Jpn J Antibiot 1985; 38 (2): 373–414.
  • Tsutou H, Nanba R, Taguchi M, et al. Fundamental and clinical studies on BRL25000 (clavulanic acid-amoxicillin) in the field of oral surgery. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 650–661.
  • Ueda J, Saito A, Shimada J, et al. Clinical studies on BRL 25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 198–215.
  • Uematsu M, Itoh T, Kikawa R, Morishima T, Kaneko A, Sasaki J. Fundamental and clinical studies on BRL25000 (clavulanic acid-amoxicillin) in oral surgery. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 640–649.
  • Ulmer WT, Zimmermann I. A controlled trial of amoxycillin with clavulanic acid (BRL 25000) against doxycycline in chronic bronchitis. J Int Med Res 1981; 9: 372–377.
  • Umbach G, Lang N, Werner H. Oral Augmentin in the treatment of urinary tract infections. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983; No. 4: 161–168.
  • Umemura S, Suwaki M, Nohara N, et al. Double blind comparative test for BRL25000 (clavulanic acid-amoxicillin) vs amoxicillin in acute skin infection. Chemotherapy (Tokyo) 1983; 31 (Suppl 2): 83–96.
  • Uri FI, Sartawi SA, Dajani YF, Masoud AA, Barakat HF. Amoxycillin/clavulanic acid (Augmentin) compared with triple drug therapy for pelvic inflammatory disease. Int J Gynecol Obstet 1992; 38 (1): 41–43.
  • Vallcorba-Plana N, Redondo Eleno M, Prieto Prieto J, et al. Cambios microbiológicos en la flora subgingival despues del tratamiento conamoxicilina-acido clavulanico. Av Periodon 1990; 1 (2): 87–92.
  • Van Der Meijden WI, Piot P, Loriaux SM, Stolz E. Amoxycillin, amoxycillin-clavulanic acid and metronidazole in the treatmentof clue cell-positive discharge. A comparative clinical and laboratory study. J Antimicrob Chemother 1987; 20 (5): 735–742.
  • Van Erps P, Nowe P, Denis LJ. A clinical trial of Augmentin in urinary tract infections. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983: 147–152.
  • Van Niekerk CH, Van Den Ende J, Louw EA, Mahaffey A, Muller FO, Hundt HKC. A pharmacokinetic study of paediatric formulations of amoxycillin plus clavulanic acid (Augmentin) in children. Proc 22nd Interscience Conf Antimicrob Agents Chemother Miami 1982. 1982: Abstr 309.
  • Verhoest P, Boulanger JC, Orfila J. A proposed new therapeutic strategy in upper genital tract infections. Proc 16th Int Congr Chemother Jerusalem 1989: Abstr.
  • Vrankova J, Kocvara R. Treatment of urinary infection by a combination of amoxycillin and clavulanic acid. Cas Lek Cesk 1983; 122 (37): 1144–1145.
  • Wald ER, Reilly JS, Casselbrant MC, Chiponis DM. Treatment of acute sinusitis in children: Augmentin versus cefaclor. Postgrad Med 1984; Augmentin Symp Suppl: 133–136.
  • Wald ER, Chiponis D, Ledesma-Medina J. Comparative effectiveness of amoxycillin and amoxycillin-clavulanate potassium in acute paranasal sinus infections in children: A double blind, placebo controlled trial. Pediatrics 1986; 77 (6): 795–800.
  • Wallace RJ, Steele LC, Brooks DL, Luman JI, Wilson RW, McLarty JW. Amoxycillin-clavulanic acid in the treatment of lower respiratory tract infections caused by beta-lactamase positive Haemophilus influenzae and Branhamella catarrhalis. Antimicrob Agents Chemother 1985; 27 (6): 912–915.
  • Wallace RJ, Brown BA, Stocks JM, Griffith DE, Mazurek GH. Comparative trial of cefixime (FIX) and amoxicillin/clavulananic acid (A/C) in adult lower respiratory infections due to Moraxella catarrhalis (M Cat) and Haemophilus influenzae (H Flu). Proc 17th Int Congr Chemother Berlin 1991: A1132.
  • Watanabe A, Oizumi K, Sasaki M, Aonuma S, Onuma K, Konno K. BRL25000 (clavulanic acid-amoxicillin) antimicrobial activity and clinical investigation on respiratory tract infections. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 176–183.
  • Watson A, Mahendra M. A multicentre therapeutic study of Augmentin in infections presenting in general practice. Excerpta Med Int Cong Ser 1980: Proc 1st Symp Augmentin 187–202.
  • Watts HF, Williams AH, Cox DM. A pilot study of cefuroxime axetil (Zinnat) and Augmentin in the treatment of skin and soft tissue infections in general practice. Clin Trials J 1987; 24 (5): 356–363.
  • Weber K, Preac-Mursic V, Neubert U, et al. Antibiotic therapy of early European Lyme Borreliosis and acrodermatitis chronica atrophicans. Ann NY Acad Sci 1988; 539: 324–345.
  • Weisser J, Wesch R, Kresken M. Clinical experience with Augmentin in German hospitals. Proc 2nd Biennial Conf Chemother Infect Dis Malig Montreux 1989; 70–71.
  • Wielemans R, Gline JP. Clinical experience with oral Augmentin in the treatment of ear, nose and throat infections in children. Proc Eur Symp Augmentin Scheveningen 1982 Excerpta Med Curr Clin Pract Ser 1983: No. 4: 341–346.
  • Wielemans R, Gline JP. Clinical experience with Augmentin in upper respiratory tract infections (URTI). Proc 22nd Interscience Conf Antimicrob Agents Chemother Miami 1982. 1982: Abstr 307.
  • Williams KJ, Hebblethwaite EM, Brown GW, Cox DM, Plested SJ. Cefuroxime axetil in the treatment of uncomplicated UTI: A comparison with cefaclor and Augmentin. Drugs Exp Clin Res 1987; 13 (2): 95–99.
  • Wolner-Hanssen P, Paavonen J, Kiviat N, et al. Ambulatory treatment of suspected pelvic inflammatory disease with Augmentin, with or without doxycycline. Am J Obstet Gynecol 1988; 158 (3 Part 1): 577–579.
  • Yamaguchi K, Chang Ch, Tanaka H, et al. Laboratory and clinical studies on BRL25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 338–348.
  • Yamamoto Y, Arat J, Hagiyam M. BRL25000 (clavulanic acid-amoxicillin) in the field of dermatology. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 594–597.
  • Yamamoto Y, Yamamoto H, Shimura H. Clinical studies of BRL25000 (clavulanic acid-amoxicillin) in surgical field. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 397–401.
  • Yamaoka S, Yamane Y, Mashimo K. Clinical investigations of BRL25000 (clavulanic acid-amoxicillin). Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 222–225.
  • Yoshida H, Saitoh K, Fuji K, et al. Clinical evaluation of BRL25000 (clavulanic acid-amoxicillin) in the field of oral surgery. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 633–639.
  • Yoshioka K, Youngs DJ, Keighley MR. A randomised prospective controlled study of ciprofloxacin with metronidazole versus amoxicillin/clavulanic acid with metronidazole in the treatment of intra-abdominal infection. Infection 1991; 19 (1): 25–29.
  • Yura J, Shinagawa N, Ishikawa S, et al. Fundamental and clinical studies on BRL25000 (clavulanic acid-amoxicillin) in the surgical field. Chemotherapy (Tokyo) 1982; 30 (Suppl 2): 379–386.
  • Zeni F, Tardy B, Page Y, Comtet C, Billard JL, Bertrand JC. Traitement de l’infection spontanee du liquide d’ascite par amoxicilline et acide calvulanique. Presse Medicale 1991; 20: 1511–1512.
  • Zoccola GC, Calogiuri PL, Ciotta D, Barbero P.. Valutazione clinica dell’efficacia terapeutica dell’associazione amoxicillina-acido clavulanico nella patologia odontostomatologica acuta. Minerva Stomatol 1988; 375: 1005–1009.
  • Neu HC. The crisis in antibiotic resistance. Science 1992; 257: 1064–1073.
  • Gould IM, Reid TMS, Golder D et al. Penetration of amoxycillin/clavulanate (Augmentin) into bronchial mucosa with different dosing regimens. Proc 7th Mediterr Congr Chemother Barcelona 1990.
  • Fernandes PB, Hardy D, Bailer R et al. Susceptibility testing of macrolide antibiotics against Haemophilus influenzae and correlation of in vitro results with in vivo efficacy in a mouse septicemia model. Antimicrob Agents Chemother 1987; 31: 1243–1250.
  • Pellegrino MB, D’Amico G, Stefani S et al. Antibacterial activity of amoxicillin/clavulanic acid against Haemophilus sp and B. catarrhalis in comparison with some macrolides, cefixime and cefuroxime. Proc 8th Mediterr Congr Chemother Athens 1992, Abstr 158.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.