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Antimicrobial Original Research Paper

Gram-negative bacteria as causative agents of ventilator-associated pneumonia and their respective resistance mechanisms

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Pages 344-358 | Received 25 Jan 2020, Accepted 25 Jun 2020, Published online: 30 Jul 2020

References

  • Koulenti D, Rello J. Hospital-acquired pneumonia in the 21st century: a review of existing treatment options and their impact on patient care. Expert Opin Pharmacother. 2006;7(12):1555–69.
  • Chastre J, Fagon JY. Ventilator-associated pneumonia. Am J Respir Crit Care Med. 2002;165(7):867–903.
  • Craven D. Epidemiology of ventilator-associated pneumonia. Chest. 2000;117(4 Suppl 2):186S–7S.
  • Dey A, Bairy I. Incidence of multidrug-resistant organisms causing ventilator-associated pneumoniae in a tertiary care hospital: a nine months prospective study. Ann Thorac Med. 2007;2(2):52–7.
  • Kliebe C, Nies B, Meyer J, Tolxdorf-Neutzling R, Wiedemann B. Evolution of plasmid-coded resistance to broad-spectrum cephalosporins. Antimicrob Agents Chemother. 1985;28(2):302–7.
  • Bradford PA. Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin Microbiol Rev. 2001;14(4):933–51.
  • Jacoby GA, Munoz-Price LS. The new beta-lactamases. N Engl J Med. 2005;352(4):380–91.
  • Rossolini GM, D'Andrea MM, Mugnaioli C. The spread of CTX-M-type extended-spectrum β-lactamases. Clin Microbial Infect. 2008;14(1):33–41.
  • Bonnet R. Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes. Antimicrob Agents Chemother. 2004;48(1):1–14.
  • Silva J, Gatica R, Aguilar C, Becerra Z, Garza-Ramos U, Velazquez M, Miranda G, Leanos B, Solorzano F, Echaniz G. Outbreak of infections with extended-spectrum β-lactamase producing Klebsiella pneumoniae in a Mexican Hospital. J Clin Microbiol. 2001;39(9):3193–6.
  • Gniadkowski M, Palucha A, Grzesiowski P, Hryniewicz W. Outbreak of ceftazidime-resistant Klebsiella pneumoniae in Warsaw, Poland; clonal spread of the TEM-47 extended-spectrum β-lactamase (ESBL)-producing strain and transfer of a plasmid carrying the SHV-5 like ESBL-encoding gene. Antimicrob Agents Chemother. 1998;42(12):3079–85.
  • Shannon K, Stapleton P, Xiang X, Johnson A, Beattie H, El Bakri F, Cookson B, French G. Extended-spectrum β-lactamase-producing Klebsiella pneumoniae strains causing nosocomial outbreak of infection in the United Kingdom. J Clin Microbiol. 1998;36(10):3105–10.
  • Essack SY. Treatment options for extended-spectrum beta-lactamase-producers. FEMS Microbiol Lett. 2000;190(2):181–4.
  • Jacoby GA. AmpC beta-lactamases. Clin Microbiol Rev. 2009;22(1):161–82.
  • Queenan AM, Bush K. Carbapenemases: the versatile beta-lactamases. Clin Microbiol Rev. 2007;20(3):440–58.
  • Cantón R, Akóva M, Carmeli Y, Giske CG, Glupczynski Y, Gniadkowski M, et al. Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe. Clin Microbiol Infect. 2012;18(5):413–31.
  • Clinical Laboratory Standard Institution. Performance standards for antimicrobial susceptibility testing, 2016. 22th informational supplement. Approved standard M100-S22. Clinical and Laboratory Standards Institute, Wayne, PA.
  • http://www.eucast.org.
  • EUCAST: European Comittee on Antimicrobial Susceptibility testing, recommendations for in vitro susceptibility testing, 2020
  • Jarlier V, Nicolas MH, Fournier G, Philippon A. Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns. Rev Infect Dis. 1988;10(4):867–78.
  • Coudron PE. Inhibitor-based methods for detection of plasmid-mediated AmpC beta-lactamases in Klebsiella spp., Escherichia coli, and Proteus mirabilis. J Clin Microbiol. 2005;43(8):4163–7.
  • Lee K, Lim YS, Yong D, Yum JH, Chong Y. Evaluation of the Hodge test and the imipenem-EDTA double-disk synergy test for differentiating metallo-beta-lactamase-producing isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol. 2003;41(10):4623–9.
  • Pasteran F, Mendez T, Guerriero L, Rapoport M, Corso A. Sensitive screening tests for suspected class A carbapenemase production in species of Enterobacteriaceae. J Clin Microbiol. 2009;47(6):1631–9.
  • Pournaras S, Markogiannakis A, Ikonomidis A, Kondyli L, Bethimouti K, Maniatis AN, Legakis NJ, Tsakris A. Outbreak of multiple clones of imipenem-resistant Acinetobacter baumannii isolates expressing OXA-58 carbapenemase in an intensive care unit. J Antimicrob Chemother. 2006;57(3):557–61.
  • Magiorakos A-P, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect. 2012;18(3):268–81.
  • Elwell LP, Falkow S. The characterization of R plasmids and the detection of plasmid-specified genes. In: Lorian V (ed). Antibiotics in Laboratory Medicine. 2nd ed. Baltimore MD: Williams and Wilkins; 1986. p. 683–721.
  • Nüesch-Inderbinen MT, Hächler H, Kayser FH. Detection of genes coding for extended-spectrum SHV beta-lactamases in clinical isolates by a molecular genetic method, and comparison with the E test. Eur J Clin Microbiol Infect Dis. 1996;15(5):398–402.
  • Arlet G, Brami G, Décrè D, Flippo A, Gaillot O, Lagrange PH, et al. Molecular characterisation by PCR-restriction fragment length polymorphism of TEM beta-lactamases. FEMS Microbiol Lett. 1995;134(2–3):203–8.
  • Woodford N, Ward ME, Kaufmann ME, Turton J, Fagan EJ, James D, et al. Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum beta-lactamases in the UK. J Antimicrob Chemother. 2004;54(4):735–43.
  • Pagani L, Mantengoli E, Migliavacca R, Nucleo E, Pollini S, Spalla M, et al. Multifocal detection of multidrug-resistant Pseudomonas aeruginosa producing the PER-1 extended-spectrum beta-lactamase in Northern Italy. J Clin Microbiol. 2004;42(6):2523–9.
  • Woodford N, Fagan EJ, Ellington MJ. Multiplex PCR for rapid detection of genes encoding CTX-M extended-spectrum (beta)-lactamases. J Antimicrob Chemother. 2006;57(1):154–5.
  • Perez-Perez FJ, Hanson ND. Detection of plasmid-mediated AmpC beta-lactamase genes in clinical isolates by using multiplex PCR. J Clin Microbiol. 2002;40(6):2153–62.
  • Yigit H, Queenan AM, Anderson GJ, Domenech-Sanchez A, Biddle JW, Steward CD, et al. Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob Agents Chemother. 2001;45(4):1151–61.
  • Naas T, Vandel W, Sougakoff W, Livermore DM, Nordmann P. Cloning and sequence analysis of the gene for a carbapenem-hydrolyzing class A beta-lactamase, Sme-1, from Serratia marcescens S6. Antimicrob Agents Chemother. 1994;38(6):1262–70.
  • Nordmann P, Mariotte S, Naas T, Labia R, Nicolas MH. Biochemical properties of a carbapenem-hydrolyzing beta-lactamase from Enterobacter cloacae and cloning of the gene into Escherichia coli. Antimicrob Agents Chemother. 1993;37(5):939–46.
  • Giakkoupi P, Xanthaki A, Kanelopoulou M, Vlahaki A, Miriagou V, Kontou S, et al. VIM-1 Metallo-beta-lactamase-producing Klebsiella pneumoniae strains in Greek hospitals. J Clin Microbiol. 2003;41(8):3893–6.
  • Yan JJ, Ko WC, Tsai SH, Wu HM, Wu JJ. Outbreak of infection with multidrug-resistant Klebsiella pneumoniae carrying blaIMP-8 in a University Medical Center in Taiwan. J Clin Microbiol. 2001;39(12):4433–9.
  • Mulvey MR, Grant JM, Plewes K, Roscoe D, Boyd DA. New Delhi metallo-β-lactamase in Klebsiella pneumoniae and Escherichia coli, Canada. Emerg Infect Dis. 2011;17(1):103–6.
  • Gülmez D, Woodford N, Palepou M-FI, Mushtaq S, Metan G, Yakupogullari Y, et al. Carbapenem-resistant Escherichia coli and Klebsiella pneumoniae isolates from Turkey with OXA-48-like carbapenemases and outer membrane protein loss. Int J Antimicrob Agents. 2008;31(6):523–6.
  • Robicsek A, Strahilevitz J, Sahm DF, Jacoby GA, Hooper DC. The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect Dis. 2006;6(10):629–40.
  • Jeong SH, Lee K, Chong Y, Yum JH, Lee SH, Choi HJ, et al. Characterization of a new integron containing VIM-2, a metallo-beta-lactamase gene cassette, in a clinical isolate of Enterobacter cloacae. J Antimicrob Chemother. 2003;51(2):397–400.
  • Turton JF, Ward ME, Woodford N, Kaufmann ME, Pike R, Livermore DM, et al. The role of ISAba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii. FEMS Microbiol Lett. 2006;258(1):72–7.
  • Saladin M, Cao VTB, Lambert T, Donay J-L, Herrmann J-L, Ould-Hocine Z, et al. Diversity of CTX-M beta-lactamases and their promoter regions from Enterobacteriaceae isolated in three Parisian hospitals. FEMS Microbiol Lett. 2002;209(2):161–8.
  • Carattoli A, Bertini A, Villa L, Falbo V, Hopkins KL, Threlfall EJ. Identification of plasmids by PCR-based replicon typing. J Microbiol Methods. 2005;63(3):219–28.
  • Bertini A, Poirel L, Mugnier PD, Villa L, Nordmann P, Carattoli A. Characterization and PCR-based replicon typing of resistance plasmids in Acinetobacter baumannii. Antimicrob Agents Chemother. 2010;54(10):4168–77.
  • Turton JF, Gabriel SN, Valderrey C, Kaufmann ME, Pitt TL. Use of sequence-based typing and multiplex PCR to identify clonal lineages of outbreak strains of Acinetobacter baumannii. Clin Microbiol Infect. 2007;13(8):807–15.
  • Bošnjak Z, Bedenić B, Mazzariol A, Jarža-Davila N, Šuto S, Kalenić S. VIM-2 beta-lactamase in Pseudomonas aeruginosa isolates from Zagreb, Croatia. Scand J Infect Dis. 2010;42(3):193–7.
  • Bedenić B, Vraneš J, Bošnjak Z, Marijan T, Mlinarić-Džepina A, Kukovec T. Emergence of CTX-M group 1 extended-spectrum β-lactamase-producing Klebsiella pneumoniae strains in the community. Med Glas. 2010;7(1):32–9.
  • Bedenić B, Firis N, Elveđi-Gašparović V, Krilanović M, Matanović K, Štimac I, et al. Emergence of multidrug-resistant Proteus mirabilis in a long-term care facility in Croatia. Wien Klin Wochenschr. 2016;128(11–12):404–13.
  • Bedenić B, Sardelić S, Luxner J, Bošnjak Z, Varda-Brkić D, Lukić-Grlić A, et al. Molecular characterization of class b carbapenemases in advanced stage of dissemination and emergence of class d carbapenemases in Enterobacteriaceae from Croatia. Infect Genet Evol. 2016;43:74–82.
  • Zujić Atalić V, Bedenić B, Kocsis E, Mazzariol A, Sardelić S, et al. Diversity of carbapenemases in clinical isolates of Enterobacteriaceae in Croatia: the results of the multicenter study. Clin Microbiol Infect. 2014; 20(11):O894–903.
  • Bedenić B, Slade M, Starčević LŽ, Sardelić S, Vranić-Ladavac M, Benčić A, et al. Epidemic spread of OXA-48 beta-lactamase in Croatia. J Med Microbiol. 2018;67(8):1031–4.
  • Jelić M, Škrlin J, Bejuk D, Košćak I, Butić I, Gužvinec M, et al. Characterization of isolates associated with emergence of OXA-48-producing Klebsiella pneumoniae in Croatia. Microb Drug Resist. 2018;24(7):973–9.
  • Franolić-Kukina I, Bedenić B, Budimir A, Herljević Z, Vraneš J, Higgins P. Clonal spread of carbapenem-resistant OXA-72-positive Acinetobacter baumannii in a Croatian university hospital. Int J Infect Dis. 2011;15(10):e706–e9.
  • Vranić-Ladavac M, Bedenić B, Minandri F, Ištok M, Bošnjak Z, Frančula-Zaninović S, et al. Carbapenem resistance and acquired class D beta-lactamases in Acinetobacter baumannii from Croatia 2009–2010. Eur J Clin Microbiol Infect Dis. 2014;33(3):471–8.
  • Bedenić B, Beader N, Godič-Torkar K, Vranić-Ladavac M, Luxner J, Veir Z, et al. Nursing home as a reservoir of carbapenem-resistant Acinetobacter baumannii. Microb Drug Resist. 2015;21(3):270–8.
  • Goić-Barišić I, Hrenović J, Kovačić A, Šeruga-Musić M. Emergence of oxacillinases in environmental carbapenem-resistant Acinetobacter baumannii associated with clinical isolates. Microb Drug Resist. 2016;22(7):559–63.

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