The Potential of Proton and Light Ion Beams in Radiotherapy

References

• Intensity Modulated Radiation Therapy Collaborative Work-ing Group. Intensity-modulated radiotherapy: current status and issues of interest, lilt J Radiat Oncol Biol Phys 2001; 51: 880–914.
   PubMed Web of Science ®Google Scholar
• Tubiana M. Eschwege F. Conformal radiotherapy and inten-sity-modulated radiotherapy clinical data. Acta Oncol 2000; 39: 555–67.
   Google Scholar
• Bonnett DE. Current developments in proton therapy: a review. Phys Med Biol 1993; 38: 1371 92.
   Google Scholar
• Levy RP, Schulte RW, Slater JD. et al. Stereotactic radio-surgery-the role of charged particles. Acta Oncol 1999; 38: 165–9.
   PubMed Web of Science ®Google Scholar
• Fuss M, Loredo LN. Blacharski PA. et al. Proton radiation therapy for medium and large choroidal melanoma: preserva-tion of the eye and its functionality. hit .1 Radiat Oncol Biol Phys 2001; 49: 1053 9.
   Google Scholar
• Munzenrider JE. Liebsch N. Proton therapy for tumors of the skull base. Strahlenther Onkol 1999; 175(Suppl): 257–63.
   Google Scholar
• The Proton Therapy Working Party. Proton therapy for base of skull chordoma: a report for the Royal College of Radiologists. Clin Oncol 2000; 12: 75–9.
   Web of Science ®Google Scholar
• Shipley WU, Verhey U. Munzenrider JE, et al. Advanced prostate cancer: the results of a randomized comparative trial of high dose irradiation boosting with conformal protons compared with conventional dose irradiation using photons alone. hit J Radiat Oncol Biol Phys 1995; 32: 3–12.
   PubMed Web of Science ®Google Scholar
• Isacsson U, Lennernas B, Grusell E. et al. Comparative treatment planning between proton and X-ray therapy in esophageal cancer. Int J Radiat Oncol Biol Phys 1998; 41: 441–50.
   Google Scholar
• Isacsson U. Hagberg H, Johansson 1(A, et al. Potential advantages of protons over conventional radiation beams for paraspinal tumours. Radiother Oncol 1997; 45: 63–70.
   Google Scholar
• Isacsson U, Montelius A, Jung B. et al. Comparative treatment planning between proton and x-ray therapy in locally advanced rectal cancer. Radiother Oncol 1996; 41: 263–72.
   Google Scholar
• Baumert BG. Lomax AJ, Miltehey V. et al. A comparison of dose distributions of proton and photon beams in stereotactic conformal radiotherapy of brain lesions. hit J Radiat Oncol Biol Phys 2001; 49: 1439–49.
   PubMed Web of Science ®Google Scholar
• Cella L, Lomax A. Miralbell R. Potential role of intensity modulated proton beams in prostate cancer radiotherapy. hit J Radiat Oncol Biol Phys 2001; 49: 217–23.
   Google Scholar
• Fuss M, Hug EB, Schaefer RA, et al. Proton radiation therapy (PRT) for pediatric optic pathway gliomas: comparison with 3D planned conventional photons and a standard photon technique. Int J Radiat Oncol Biol Phys 1999: 45: 1117–26.
   PubMed Web of Science ®Google Scholar
• Miralbell R, Crowell C. Suit H. Potential improvement of three dimensional treatment planning and proton therapy in the outcome of maxillary sinus cancer. Int J Radiat Oncol Biol Phys 1997; 22: 305–10.
   Google Scholar
• Miralbell R. Lomax A. Bortfeld T, et al. Potential role of proton therapy in the treatment of pediatric medulloblastoma/ primitive neuroectodermal tumors: reduction of the supraten-torial target volume. Int J Radiat Oncol Biol Phys 1997: 38: 477–84.
   PubMed Web of Science ®Google Scholar
• Miralbell R. Lomax A, Russo M. Potential role of proton therapy in the treatment of pediatric medulloblastoma/primi-tive neuro-ectodermal tumors: spinal theca irradiation. Int J Radiat Oncol Biol Phys 1997; 38: 805–11.
   Google Scholar
• Oelfke U. Bortfeld T. Intensity modulated radiotherapy with charged particle beams: studies of inverse treatment planning for rotation therapy. Med Phys 2000; 27: 1246–57.
   Google Scholar
• Zurlo A, Lomax A. Hoess A. et al. The role of proton therapy in the treatment of large irradiation volumes: a comparative planning study of pancreatic and biliary tumors. Int J Radiat Oncol Biol Phys 2000; 48: 277–88.
   Google Scholar
• Cozzi L, Fogliata A. Lomax A, et al. A treatment planning comparison of 3D conformal therapy, intensity modulated photon therapy and proton therapy for treatment of advanced head and neck tumours. Radiother Oncol 2001; 61: 287 927.
   Google Scholar
• Lee C, Tait D. Nahum A, et al. Comparison of proton therapy and conformal X-ray therapy in non-small cell lung cancer (NSCLC). Br J Radiat 1999; 72: 1078–84.
   PubMed Web of Science ®Google Scholar
• Lin R, Hug EB, Schaefer RA, et al. Conformal proton radiation therapy of the posterior fossa: a study comparing protons with three-dimensional planned photons in limiting dose to auditory structures. Int J Radiat Oncol Biol Phys 2000; 48: 1219–26.
   PubMed Web of Science ®Google Scholar
• Johansson J, Isacsson U, Lindman H. et al. Node-positive left-sided breast cancer patients after breast-conserving surgery: potential outcomes of radiotherapy modalities and techniques. Radiother Oncol 2002; 65: 89–98.
   Google Scholar
• Fogliata A, Bolsi A. Cozzi L. Critical appraisal of treatment techniques based on conventional photon beams, intensity modulated photon beams and proton beams for therapy of intact breast. Radiother Oncol 2002; 62: 137–45.
   Google Scholar
• Paganetti H, Niemierko A. Ancukiewicz M, et al. Relative biological effectiveness (RBE) values for proton beam therapy. Int J Radiat Oncol Biol Phys 2002; 53: 407-2 1.
   PubMed Web of Science ®Google Scholar
• Tilly N. Radiobiological investigations of proton and light ion therapy. Stockholm. Thesis: Stockholm University; 2002.
   Google Scholar
• Brahme A. Development of radiation therapy optimization. Acta Oncol 2000; 39: 579–95.
   PubMed Web of Science ®Google Scholar
• Brahme A, Nilsson J, Belkic D. Biologically optimized radia-tion therapy Acta Oncol 2001: 40: 725–34.
   Google Scholar
• Tilikidis A, Brahme A. Microdosimetric description of beam quality and biological effectiveness in radiation therapy. Acta Oncol 1994; 33: 457 69.
   PubMed Web of Science ®Google Scholar
• Stenerlow B, Pettersson OA. Essand M, et al. Irregular variations in radiation sensitivity when the linear energy transfer is increased. Radiother Oncol 1995; 36: 133–42.
   PubMed Web of Science ®Google Scholar
• Peters U. Targeting hypoxia in head and neck cancer. Acta Oncol 2001; 40: 937–40.
   PubMed Web of Science ®Google Scholar
• Zackrisson B, Kjellen E, Glimelius B, et al. and the Swedish Cancer Society Investigation Group. Sensitizing and protective substances in radiotherapy and predictive assays. Acta Oncol 2002:41: 615–22.
   Google Scholar
• Steel GG. Basic clinical radiology. 3rd ed. London: Edward Arnold: 2002.
   Google Scholar
• Kraft G. Tumor therapy with ion beams. Nucl Instr Meth Phys Res A 2000: 454: 1–10.
   Web of Science ®Google Scholar
• Brahme A, Lewensohn R, Ringborg U, et al. Design of a centre for biologically optimised light ion therapy in Stockholm. Nucl Inst Meth B 2001: 184: 569–88.
   Web of Science ®Google Scholar
• Koike S, Ando K. Uzawa A. et al. Significance of fractionated irradiation for the biological therapeutic gain of carbon ions. Radiat Prot Dosimetry 2002; 99" 405–8.
   Google Scholar
• Mizoe J. Tsujii H, Kamada T et al. Preliminary results of carbon-ion radiotherapy for advanced head and neck cancer. Int J Radiat Oncol Biol Phys 2000; 46: 691.
   Google Scholar
• Schulz-Ertner D. Haberer T, Jakcl O. et al. Radiotherapy for chordomas and low-grade chondrosarcomas of the skull base with carbon ions. Int J Radiat Oncol Biol Phys 2002; 53: 36–42.
   Google Scholar
• Russel KJ. Caplan RJ. Laramore GE. et al. Photon versus fast neutron external beam radiotherapy in the treatment of locally advanced prostate cancer: results of a randomized prospective trial. Int J Radiat Oncol Biol Phys 1993; 28: 47–54.
   Web of Science ®Google Scholar
• Griffin TW, Laramore GE. Neutron radiation and prostate cancer. Int J Radiat Oncol Biol Phys 1995; 33: 231–2.
   PubMed Web of Science ®Google Scholar
• Pickles T, Goodman GB. Fryer Ci, et al Pion conformal radiation of prostate cancer: results of a randomized study Int J Radiat Oncol Biol Phys 1998; 43: 47–55.
   Google Scholar
• Haraf D.I. Rubin SJ, Sweeney P. et al. Photon neutron mixed-beam radiotherapy of locally advanced prostate cancer. Int J Radiat Oncol Biol Phys 1995; 33: 3–14.
   PubMed Web of Science ®Google Scholar
• Joiner MC, Marples B, Lambin P, et al. Low-dose hypersensi-tivity: current status and possible mechanisms. Int J Radiat Oncol Biol Phys 2001; 49: 379–89.
   PubMed Web of Science ®Google Scholar
• Skarsgard LD. Hill AA. Acheson DK. Evidence for two forms of substructure in the cell survival curve-mechanisms and clinical consequences. Acta Oncol 1999; 38: 895–902.
   PubMed Web of Science ®Google Scholar
• Turesson I, Bernefors R, Book M, et al. Normal tissue response to low doses ofradiotherapy assessed by molecular markers. A study of skin in patients treated for prostate cancer. Acta Oncol 2001:40:941–51.
   Google Scholar
• Turesson I. Carlsson J, Brahme A, Glimelius B. Zackrisson B, Stenerlow B and the Swedish Cancer Society Investigation Group. Biological response to radiation therapy. Acta Oncol 2003; 42: 92–106.
   Google Scholar
• Suit H. The Gray Lecture 2001: coming technical advances in radiation oncology Int J Radiat Oncol Biol Phys 2002; 53: 798–809
   Google Scholar
• Swedish Cancer Society. Investigation concerning clinical treatment studies. Canccrfonden, 1999.
   Google Scholar
• Mattsson S, Brahme A. Carlsson J. ct al. Swedish Cancer Society radiation therapy research investigation. Acta Oncol 2002:41: 596–603.
   Google Scholar