Dicer induced reactive oxygen species inhibit hepatocellular carcinoma through interacting with cytochrome c oxidase

References

• Sung H, Ferlay J, Siegel RL. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. 2021.
   Google Scholar
• Liu S, An J, Lin J, et al. Single nucleotide polymorphisms of microRNA processing machinery genes and outcome of hepatocellular carcinoma. PLoS One. 2014;9(3):e92791.
   PubMed Web of Science ®Google Scholar
• Saikolappan S, Kumar B, Shishodia G, et al. Reactive oxygen species and cancer: a complex interaction. Cancer Lett. 2019;452:132–143.
   PubMed Web of Science ®Google Scholar
• Aggarwal V, Tuli HS, Varol A, et al. Role of reactive oxygen species in cancer progression: Molecular mechanisms and recent advancements. Biomolecules. 2019;9(11):735.
   PubMed Web of Science ®Google Scholar
• Kuo MT, Savaraj N. Roles of reactive oxygen species in hepatocarcinogenesis and drug resistance gene expression in liver cancers. Mol Carcinog. 2006;45(9):701–709.
   PubMed Web of Science ®Google Scholar
• Gentric G, Maillet V, Paradis V, et al. Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease. J Clin Invest. 2015;125(3):981–992.
   PubMed Web of Science ®Google Scholar
• Wang F, Yang JL, Yu KK, et al. Activation of the NF-κB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma. Mol Cancer. 2015;14:10.
   PubMed Web of Science ®Google Scholar
• Dai X, Wang L, Deivasigamni A, et al. A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma. Oncotarget. 2017;8(8):12831–12842.
   PubMedGoogle Scholar
• Campian JL, Gao X, Qian M, et al. Cytochrome c oxidase activity and oxygen tolerance. J Biol Chem. 2007;282(17):12430–12438.
   PubMed Web of Science ®Google Scholar
• Oliva CR, Nozell SE, Diers A, III, et al. Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. J Biol Chem. 2010;285(51):39759–39767.
   PubMed Web of Science ®Google Scholar
• Foulkes WD, Priest JR, Duchaine TF. DICER1: mutations, microRNAs and mechanisms. Nat Rev Cancer. 2014;14(10):662–672.
   PubMed Web of Science ®Google Scholar
• Ventura A, Jacks T. MicroRNAs and cancer: short RNAs go a long way. Cell. 2009;136(4):586–591.
   PubMed Web of Science ®Google Scholar
• Caruso S, Calderaro J, Letouzé E, et al. Germline and somatic DICER1 mutations in familial and sporadic liver tumors. J Hepatol. 2017;66(4):734–742.
   PubMed Web of Science ®Google Scholar
• Heravi-Moussavi A, Anglesio MS, Cheng SW, et al. Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers. N Engl J Med. 2012;366(3):234–242.
   PubMed Web of Science ®Google Scholar
• Yang R, Xu J, Hua X, et al. Overexpressed miR-200a promotes bladder cancer invasion through direct regulating dicer/miR-16/JNK2/MMP-2 axis. Oncogene. 2020;39(9):1983–1996.
   PubMed Web of Science ®Google Scholar
• Minghu F, Baohua C, Helong C, et al. miR-186 mediated up-regulation of Dicer1 inhibits Colon cancer invasion and metastasis. Current Immunology. 2020;40:177–186.
   Google Scholar
• Dong J, Wang J, Shan C, et al. MicroRNA-892a regulates laryngocarcinoma cell proliferation via dicer. Exp Biol Med (Maywood). 2020;245(14):1222–1232.
   PubMed Web of Science ®Google Scholar
• Gao C, Li X, Tong B, et al. Up-regulated expression of dicer reveals poor prognosis in laryngeal squamous cell carcinoma. Acta Otolaryngol. 2014;134(9):959–963.
   PubMed Web of Science ®Google Scholar
• Bian XJ, Zhang GM, Gu CY, et al. Down-regulation of dicer and Ago2 is associated with cell proliferation and apoptosis in prostate cancer. Tumour Biol. 2014;35(11):11571–11578.
   PubMedGoogle Scholar
• Faber C, Horst D, Hlubek F, et al. Overexpression of dicer predicts poor survival in colorectal cancer. Eur J Cancer. 2011;47(9):1414–1419.
   PubMed Web of Science ®Google Scholar
• Faggad A, Budczies J, Tchernitsa O, et al. Prognostic significance of dicer expression in ovarian cancer-link to global microRNA changes and oestrogen receptor expression. J Pathol. 2010;220(3):382–391.
   PubMed Web of Science ®Google Scholar
• Zhang L, Wang C, Liu S, et al. Prognostic significance of dicer expression in hepatocellular carcinoma. Oncol Lett. 2016;11(6):3961–3966.
   PubMed Web of Science ®Google Scholar
• Wu X, Chen X, Liu H, et al. Rescuing dicer expression in inflamed Colon tissues alleviates colitis and prevents colitis-associated tumorigenesis. Theranostics. 2020;10(13):5749–5762.
   PubMed Web of Science ®Google Scholar
• Chen X, Li WF, Wu X, et al. Dicer regulates non-homologous end joining and is associated with chemosensitivity in Colon cancer patients. Carcinogenesis. 2017;38(9):873–882.
   PubMed Web of Science ®Google Scholar
• Yang Y, Ishak Gabra MB, Hanse EA, et al. MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1. Nat Commun. 2019;10(1):809.
   PubMedGoogle Scholar
• Li Q, Liu X, Yin Y, et al. Insulin regulates glucose consumption and lactate production through reactive oxygen species and pyruvate kinase M2. Oxid Med Cell Longev. 2014;2014:504953.
   PubMed Web of Science ®Google Scholar
• Zhang K, Wu L, Zhang P, et al. miR-9 regulates ferroptosis by targeting glutamic-oxaloacetic transaminase GOT1 in melanoma. Mol Carcinog. 2018;57(11):1566–1576.
   PubMed Web of Science ®Google Scholar
• Li SZ, Hu YY, Zhao J, et al. MicroRNA-34a induces apoptosis in the human glioma cell line, A172, through enhanced ROS production and NOX2 expression. Biochem Biophys Res Commun. 2014;444(1):6–12.
   PubMed Web of Science ®Google Scholar
• Akan I, Akan S, Akca H, et al. Multidrug resistance-associated protein 1 (MRP1) mediated vincristine resistance: effects of N-acetylcysteine and buthionine sulfoximine. Cancer Cell Int. 2005;5(1):22.
   PubMedGoogle Scholar
• Oliva CR, Markert T, Ross LJ, et al. Identification of small molecule inhibitors of human cytochrome c oxidase that target chemoresistant glioma cells. J Biol Chem. 2016;291(46):24188–24199.
   PubMed Web of Science ®Google Scholar
• Zhang S, Guo Z, Xu J, et al. miR-502-mediated histone methyltransferase SET8 expression is associated with clear cell renal cell carcinoma risk. Oncol Lett. 2017;14(6):7131–7138.
   PubMed Web of Science ®Google Scholar
• Jia Y, Li R, Cong R, et al. Maternal low-protein diet affects epigenetic regulation of hepatic mitochondrial DNA transcription in a sex-specific manner in newborn piglets associated with GR binding to its promoter. PLoS One. 2013;8(5):e63855.
   PubMed Web of Science ®Google Scholar
• Gordillo GM, Biswas A, Khanna S, et al. Dicer knockdown inhibits endothelial cell tumor growth via microRNA 21a-3p targeting of nox-4. J Biol Chem. 2014;289(13):9027–9038.
   PubMed Web of Science ®Google Scholar
• Shilo S, Roy S, Khanna S, et al. Evidence for the involvement of miRNA in redox regulated angiogenic response of human microvascular endothelial cells. Arterioscler Thromb Vasc Biol. 2008;28(3):471–477.
   PubMed Web of Science ®Google Scholar
• Chen Z, Li Y, Zhang H, et al. Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression. Oncogene. 2010;29(30):4362–4368.
   PubMed Web of Science ®Google Scholar
• Das S, Ferlito M, Kent OA, et al. Nuclear miRNA regulates the mitochondrial genome in the heart. Circ Res. 2012;110(12):1596–1603.
   PubMed Web of Science ®Google Scholar
• Aschrafi A, Schwechter AD, Mameza MG, et al. MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons. J Neurosci. 2008;28(47):12581–12590.
   PubMed Web of Science ®Google Scholar
• Chesney J, Telang S. Regulation of glycolytic and mitochondrial metabolism by ras. Curr Pharm Biotechnol. 2013;14(3):251–260.
   PubMed Web of Science ®Google Scholar
• Kadenbach B, Hüttemann M, Arnold S, et al. Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase. Free Radic Biol Med. 2000;29(3-4):211–221.
   PubMed Web of Science ®Google Scholar
• Leadsham JE, Sanders G, Giannaki S, et al. Loss of cytochrome c oxidase promotes RAS-Dependent ROS production from the ER resident NADPH oxidase, Yno1p, in yeast. Cell Metab. 2013;18(2):279–286.
   PubMed Web of Science ®Google Scholar