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The Journal of Protein Folding Disorders
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Letter to the Editor

Absence of an increased wall thickness does not rule out cardiac amyloidosis

Steven A. Mullera Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands;b Netherlands Heart Institute, Utrecht, Utrecht, Netherlands;c Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart’ (ERN GUARDHEART),  http://guardheart.ern-net.euCorrespondence[email protected]
View further author information
,
Anouk Achtend Department of Cardiology, Maastricht University, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The NetherlandsView further author information
,
Manon G. van der Meera Department of Cardiology, University Medical Center Utrecht, Utrecht, NetherlandsView further author information
,
Peter-Paul Zwetsloota Department of Cardiology, University Medical Center Utrecht, Utrecht, NetherlandsView further author information
,
Sandra Sanders-van Wijke Department of Cardiology, Zuyderland Medical Centre, Heerlen, The NetherlandsView further author information
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Pim van der Harsta Department of Cardiology, University Medical Center Utrecht, Utrecht, NetherlandsView further author information
,
J. Peter van Tintelenc Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart’ (ERN GUARDHEART),  http://guardheart.ern-net.eu;f Department of Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, The NetherlandsView further author information
,
Anneline S. J. M. te Rielea Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands;b Netherlands Heart Institute, Utrecht, Utrecht, Netherlands;c Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart’ (ERN GUARDHEART),  http://guardheart.ern-net.euView further author information
,
Vanessa van Empeld Department of Cardiology, Maastricht University, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The NetherlandsView further author information
,
Christian Knackstedtd Department of Cardiology, Maastricht University, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The NetherlandsView further author information
&
Marish I. F. J. Oerlemansa Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands;c Member of the European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart: ERN GUARD-Heart’ (ERN GUARDHEART),  http://guardheart.ern-net.euView further author information
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Received 22 Dec 2023, Accepted 19 Apr 2024, Published online: 20 May 2024

References

  • Brons M, Muller SA, Rutten FH, et al. Evaluation of the cardiac amyloidosis clinical pathway implementation: a real-world experience. Eur Heart J Open. 2022;2(2):oeac011. doi: 10.1093/ehjopen/oeac011.
  • Garcia-Pavia P, Rapezzi C, Adler Y, et al. Diagnosis and treatment of cardiac amyloidosis: a position statement of the ESC working group on myocardial and pericardial diseases. Eur Heart J. 2021;42(16):1554–1568. doi: 10.1093/eurheartj/ehab072.
  • Sammani A, Jansen M, de Vries NM, et al. Automatic identification of patients with unexplained left ventricular hypertrophy in electronic health record data to improve targeted treatment and family screening. Front Cardiovasc Med. 2022;9:768847. doi: 10.3389/fcvm.2022.768847.
  • Devesa A, Camblor Blasco A, Pello Lázaro AM, et al. Prevalence of transthyretin amyloidosis in patients with heart failure and no left ventricular hypertrophy. ESC Heart Fail. 2021;8(4):2856–2865. doi: 10.1002/ehf2.13360.
  • Arana-Achaga X, Goena-Vives C, Villanueva-Benito I, et al. Development and validation of a prediction model and score for transthyretin cardiac amyloidosis diagnosis: t -Amylo. JACC Cardiovasc Imaging. 2023;16(12):1567–1580. doi: 10.1016/j.jcmg.2023.05.002.
  • Davies DR, Redfield MM, Scott CG, et al. A simple score to identify increased risk of transthyretin amyloid cardiomyopathy in heart failure with preserved ejection fraction. JAMA Cardiol. 2022;7(10):1036–1044. doi: 10.1001/jamacardio.2022.1781.
  • Boldrini M, Cappelli F, Chacko L, et al. Multiparametric echocardiography scores for the diagnosis of cardiac amyloidosis. JACC Cardiovasc Imaging. 2020;13(4):909–920. doi: 10.1016/j.jcmg.2019.10.011.
  • Aimo A, Tomasoni D, Porcari A, et al. Left ventricular wall thickness and severity of cardiac disease in women and men with transthyretin amyloidosis. Eur J Heart Fail. 2023;25(4):510–514. doi: 10.1002/ejhf.2824.

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