Publication Cover
Redox Report
Communications in Free Radical Research
Volume 22, 2017 - Issue 6
825
Views
8
CrossRef citations to date
0
Altmetric
RESEARCH ARTICLE

3-methoxy aroylhydrazones – free radicals scavenging, anticancer and cytoprotective potency

ORCID Icon, , , , & ORCID Icon

References

  • Dröge W. Free radicals in the physiological control of cell function. Physiol Rev. 2002;82(1):47–95. doi: 10.1152/physrev.00018.2001
  • Valko M, Leibfritz D, Moncol J, et al. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol. 2007;39(1):44–84. doi: 10.1016/j.biocel.2006.07.001
  • Pham-Huy LA, He H, Pham-Huy C. Free radicals, antioxidants in disease and health. Int J Biomed Sci. 2008;4(2):89–96.
  • Júnior WB, Alexandre-Moreira MS, Alves MA, et al. Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their zinc(II) complexes. Molecules. 2011;16(8):6902–6915. doi: 10.3390/molecules16086902
  • El-Sayed MAA, Adbel-Aziz NI, Abdel-Aziz AAM, et al. Design, synthesis and biological evaluation of substituted hydrazones and pyraloze derivatives as selective COX-2 inhibitors: Molecular docking study. Bioorg Med Chem. 2011;19(11):3416–3424. doi: 10.1016/j.bmc.2011.04.027
  • Kumar P, Narasimhan B. Hydrazides/hydrazones as antimicrobial and anticancer agents in the new millennium. Mini Rev Med Chem. 2013;13(7):971–987. doi: 10.2174/1389557511313070003
  • Metwally KA, Abdel-Aziz LM, Lashine ESM, et al. Hydrazones of 2-aryl-quinoline-4-carboxylic acid hydrazides: synthesis and preliminary evaluation as antimicrobial agents. Bioorg Med Chem. 2006;14(24):8675–8682. doi: 10.1016/j.bmc.2006.08.022
  • Oviddiu O, Ndongo J, Moldovan C, et al. Synthesis and antimicrobial activity of some new 2-hydrazone-thiazoline-4-ones. Farmacia. 2012;60(6):785–797.
  • Silva AG, Zapata-Sudo G, Kummerle AE, et al. Synthesis and vasodilatory activity of new N-acylhydrazone derivatives, designed as LASSBio-294 analogues. Bioorg Med Chem. 2005;13(10):3431–3437. doi: 10.1016/j.bmc.2005.03.003
  • Jois HS, Kalluraya B, Vishwanath T. Synthesis, spectroscopic properties and antioxidant activity of bis-hydrazones and schiff's bases derived from terephthalic dihydrazide. J Fluoresc. 2015;25(3):481–488. doi: 10.1007/s10895-015-1558-5
  • Nikolaevskii A, Kniga O, Khizhan E, et al. Antioxidant activity of hydrazones with sterically hindered phenol fragments. Russ J Phys Chem A. 2012;86(12):1816–1820. doi: 10.1134/S0036024412120205
  • Belkheiri N, Bouguerne B, Bedos-Belval F, et al. Synthesis and antioxidant activity evaluation of a syringic hydrazones family. Eur J Med Chem. 2010;45(7):3019–3026. doi: 10.1016/j.ejmech.2010.03.031
  • Nikolova-Mladenova B, Halachev N, Iankova R, et al. Synthesis, characterization and cytotoxic activity of new salicylaldehyde benzoylhydrazone derivatives as potential anti-proliferative agents. Arzneimittel For/Drug Res. 2011;61(12):714–718.
  • Liu Z, Jiao Y, Wang Y, et al. Polysaccharides-based nanoparticles as drug delivery systems. Adv Drug Deliv Rev. 2008;60(15):1650–1662. doi: 10.1016/j.addr.2008.09.001
  • Porfire AS, Zabaleta V, Gamazo C, et al. Influence of dextran on the bioadhesive properties of poly(anhydride) nanoparticles. Int J Pharm. 2010;390(1):37–44. doi: 10.1016/j.ijpharm.2009.08.017
  • Kumar MN, Muzzarelli RA, Muzzarelli C, et al. Chitosan chemistry and pharmaceutical perspectives. Chem Rev. 2004;104(12):6017–6084. doi: 10.1021/cr030441b
  • Baldrick P. The safety of chitosan as a pharmaceutical excipient. Regul Toxicol Pharmacol. 2010;56(3):290–299. doi: 10.1016/j.yrtph.2009.09.015
  • Hadjimitova V, Traykov T, Mileva M, et al. Effect of some psychotropic drugs on luminol-dependent chemiluminescence induced by O2.-,OH., HOCL. Z Naturforsch C. 2002;57c:1066–1071.
  • Halliwell B, Gutteridge JM, Aruoma OI. The deoxyribose method: a simple “test-tube” assay for determination of rate constants for reactions of hydroxyl radicals. Anal Biochem. 1987;165(1):215–219. doi: 10.1016/0003-2697(87)90222-3
  • Re R, Pellegrini N, Proteggente A, et al. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med. 1999;26(9–10):1231–1237. doi: 10.1016/S0891-5849(98)00315-3
  • Traykov T, Hadjimitova V, Goliysky P, et al. Effect of phenothiazines on activated macrophage-induced luminol-dependent chemiluminescence. Gen Physiol Biophys. 1997;16(1):3–14.
  • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983;65(1–2):55–63. doi: 10.1016/0022-1759(83)90303-4
  • Van Dyke K, Van Dyke C, Woodfork K, editors. Luminescence biotechnology: instruments and applications. Boca Raton: CRC Press; 2002.
  • Roda A, Guardigli M, Pasini P. Bioluminescence and chemiluminescence in drug screening. Anal Bioanal Chem. 2003;377(5):826–833. doi: 10.1007/s00216-003-2096-6
  • Campbell AK. Chemiluminescence: principles and applications in biology and medicine. Cambridge: VCH; 1988. chap 5.
  • Schwamberger G, Flesh I, Ferber E. Tumorocidal effector molecules of murine macrophages. Pathobiology. 1991;59(4):248–253. doi: 10.1159/000163656
  • Sies H, de Groot H. Role of reactive oxygen species in cell toxicity. Toxicol Lett. 1992;64–65:547–551.
  • Conner EM, Grisham MB. Inflammation, free radicals, and antioxidants. Nutrition. 1996;12(4):274–277. doi: 10.1016/S0899-9007(96)00000-8
  • Forman HJ, Torres M. Redox signaling in macrophages. Mol Aspects Med. 2001;22(4–5):189–216. doi: 10.1016/S0098-2997(01)00010-3
  • Forman HJ, Torres M. Signaling by the respiratory burst in macrophages. IUBMN Life. 2001;51(6):365–371. doi: 10.1080/152165401753366122
  • Avakumova N, Hadjimitova V, Traykov T. Inhibition of oxygen free radicals induced luminol-dependent chemiluminescence by 4-methoxy derivatives of salicylaldehyde benzoyl hydrazine. Luminescence. 2014;29(S1):61–62.
  • Leopoldini M, Russo N, Toscano M. The molecular basis of working mechanism of natural polyphenolic antioxidants. Food Chem. 2011;125:288–306. doi: 10.1016/j.foodchem.2010.08.012
  • Wright JS, Johnson ER, DiLabio GA. Predicting the activity of phenolic antioxidants: theoretical method, analysis of substituent effects, and application to major families of antioxidants. J Am Chem Soc. 2001;123(6):1173–1183. doi: 10.1021/ja002455u
  • Demirel Özel A, Durmuş Z, Yılmaz İ, et al. Electroreduction of some substituted hydrazones on platinum electrode in dimethyl formamide. Acta Chim Slov. 2009;56:797–806.
  • Bakalbassis EG, Lithoxoidou AT, Vafiadis AP. Theoretical insights, in the liquid phase, into the antioxidant mechanism-related parameters in the 2- monosubstituted phenols. J Phys Chem A. 2006;110:11151–11159. doi: 10.1021/jp061718p
  • Kareem HS, Ariffin A, Nordin N, et al. Correlation of antioxidant activities with theoretical studies for new hydrazone compounds bearing a 3,4,5-trimethoxy benzyl moiety. Eur J Med Chem. 2015;103:497–505. doi: 10.1016/j.ejmech.2015.09.016

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.