The emerging role of irisin in experimentally induced arthritis: a recent update involving HMGB1/MCP1/Chitotriosidase I–mediated necroptosis

References

• Belizário J, Vieira-Cordeiro L, Enns S. Necroptotic cell death signaling and execution pathway: lessons from knockout mice. Mediators Inflamm. 2015;2015:1.
   Web of Science ®Google Scholar
• Peltzer N, Walczak H. Cell death and inflammation – a vital but dangerous liaison. Trends Immunol. 2019;40(5):387–402.
   PubMed Web of Science ®Google Scholar
• Xingfeng Q, Yingying Z, Jiahuai H. RIP3 is an upregulator of aerobic metabolism and the enhanced respiration by necrosomal RIP3 feeds back on necrosome to promote necroptosis. Cell Death Differ. 2018;25(5):821–824.
   PubMed Web of Science ®Google Scholar
• Roh JS, Sohn DH. Damage-Associated molecular patterns in inflammatory diseases. Immune Netw. 2018;18(4):e27.
   PubMed Web of Science ®Google Scholar
• Martinotti S, Patrone M, Ranzato E. Emerging roles for HMGB1 protein in immunity, inflammation, and cancer. Immunotargets Ther. 2015;4:101–109.
   PubMed Web of Science ®Google Scholar
• He M, Bianchi ME, Coleman TR, et al. Exploring the biological functional mechanism of the HMGB1 / TLR4 / MD-2 complex by surface plasmon resonance. Mol Med. 2018;24(1):21.
   PubMedGoogle Scholar
• Najafov A, Chen H, Yuan J. Necroptosis and cancer. Trends Cancer. 2017;3(4):294–301.
   PubMed Web of Science ®Google Scholar
• Oliveira SR, Amaral JD, Rodrigues CMP. Mechanism and disease implications of necroptosis and neuronal inflammation. Cell Death Dis. 2018;9(9):903.
   PubMedGoogle Scholar
• Shan B, Pan H, Najafov A, et al. Necroptosis in development and diseases. Genes Dev. 2018;32(5-6):327–340.
   PubMed Web of Science ®Google Scholar
• Kim Y, Oh HC, Jang Won Park JW, et al. Diagnosis and treatment of inflammatory joint disease. Hip Pelvis. 2017;29(4):211–222.
   PubMedGoogle Scholar
• Guo Q, Wang Y, Xu D, et al. Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies. Bone Res. 2018;6:15.
   PubMed Web of Science ®Google Scholar
• Scanzello CR. Chemokines and inflammation in osteoarthritis: insights from patients and animal models. J Orthop Res. 2017;35(4):735–739.
   PubMed Web of Science ®Google Scholar
• Chang YC, Soriano M, Hahn RA, et al. Expression of cytokines and chemokines in mouse skin treated with sulfur mustard. Toxicol Appl Pharmacol. 2018;355:52–59.
   PubMed Web of Science ®Google Scholar
• Elmonem MA, van den Heuvel LP, Levtchenko EN. Immunomodulatory effects of Chitotriosidase enzyme. Enzyme Res. 2016;2016:1.
   Google Scholar
• Kanneganti M, Kamba A, Mizoguchi E. Role of chitotriosidase (chitinase 1) under normal and disease conditions. J Epithel Biol Pharmacol. 2012;5:1–9. PMID: 23439988.
   PubMedGoogle Scholar
• Hao F, Lee JR, Zhong L, et al. Hybrid micelles containing methotrexate-conjugated polymer and co-loaded with microRNA-124 for rheumatoid arthritis therapy. Theranostics. 2019;9(18):5282–5297.
   PubMed Web of Science ®Google Scholar
• Bubak MP, Heesch MWS, Shute RJ, et al. Irisin and fibronectin type III domain-containing 5 responses to exercise in different environmental conditions. Int J Exerc Sci. 2017;10(5):666–680. PMID: 28966707.
   PubMedGoogle Scholar
• Munoz IYM, Romero ESC, Garcia JJG. Irisin a novel metabolic biomarker: present knowledge and future directions. Int J Endocrinol. 2018;2018:1.
   Web of Science ®Google Scholar
• Bilski J, Mazur-Bialy A, Wojcik D, et al. Effect of forced physical activity on the severity of experimental colitis in normal weight and obese mice. Involvement of oxidative stress and proinflammatory biomarkers. Nutrients. 2019;11(5):1127.
   PubMed Web of Science ®Google Scholar
• Saleh BO, Majeed MJ, Oreaby GM. Irisin impact as a medication that ameliorate and hinder the development of insulin resistance associated disorders without regular exercise (experimental study). IOSR J Dent Med Sci. 2014 Sept;13(9):28–35. doi:10.9790/0853-13932835. Ver. III.
   Google Scholar
• Trentham DE, Townes AS, Kang AH. Autoimmunity to type II collagen an experimental model of arthritis. J Exp Med. 1977;146:857–868. doi:10.1084/jem.146.3.857.
   PubMed Web of Science ®Google Scholar
• Carlson BC, Jansson ÅM, Larsson A, et al. The endogenous adjuvant squalene can induce a chronic T-cell- mediated arthritis in rats. Am J Pathol. 2000;156:2057–2065.
   PubMed Web of Science ®Google Scholar
• Rioja I, Bush KA, Buckton JB, et al. Joint cytokine quantification in two rodent arthritis models: kinetics of expression, correlation of mRNA and protein levels and response to prednisolone treatment. ClinExpImmunol. 2004;137(1):65–73. doi:10.1111/j.1365-2249.2004.02499.x.
   Google Scholar
• Lowry OH,: Rosebrough NJ, Farr AL and Randall RJ. Protein measurement with the Folin phenol reagent. J BiolChem. 1952;193(1):265–275. PMID:14907713.
   Web of Science ®Google Scholar
• El-Magd MA, Abbas HE, El-kattawy AM, et al. Novel polymorphisms of the IGF1R gene and their association with average daily gain in Egyptian buffalo (Bubalus bubalis). Domest Anim Endocrinol. 2013;45(2):105–110.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25(4):402–408.
   PubMed Web of Science ®Google Scholar
• Hollak C, Weely S, Oers M, et al. Marked elevation of plasma chitotriosidase activity. A novel hallmark of Gaucher disease. J Clin Invest. 1994;93(3):1288. doi:10.1172/JCI117084.
   PubMed Web of Science ®Google Scholar
• Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95:351–358. doi:10.1016/0003-2697(79)90738-3.
   PubMed Web of Science ®Google Scholar
• Marwan S, Samir A, Khalid S. Serum nitric oxide and peroxynitrite levels in adult sero-positive rheumatoid arthritis treated with disease modifying antirheumatic drugs: a preliminary report. Turk J Med Sci. 2010;40(2):191–197. doi:10.3906/sag-0809-32.
   Web of Science ®Google Scholar
• Drury RA, Wallington EA. Carletons histological technique. 5th ed. Oxford: Oxford University Press; 1980. p. 241–242.
   Google Scholar
• Ramos-Vara JA. Technical aspects of immunohistochemistry. Vet Pathol. 2005;42(4):405–426.
   PubMed Web of Science ®Google Scholar
• Kanter M, Uysal T, Kara O. Depression of glucose levels and partial restoration of pancreatic (β) cell damage by melatonin in streptozotozin- induced diabetic rats. Arch Toxicol. 2006;80:362–369.
   PubMed Web of Science ®Google Scholar
• Carson FL. Histotechnology a self- instructural text. 2nd ed.; 1996; p. 154–156.
   Google Scholar
• Firestein GS. Evolving concepts of rheumatoid arthritis. Nature. 2003;423(6937):356.
   PubMed Web of Science ®Google Scholar
• Lee SH, Ye Kwon J, Kim SY, et al. Interferon-gamma regulates inflammatory cell death by targeting necroptosis in experimental autoimmune arthritis. Sci Rep. 2017;7(1):10133.
   PubMedGoogle Scholar
• Jhun J, Lee SH, Kim SY, et al. RIPK1 inhibition attenuates experimental autoimmune arthritis via suppression of osteoclastogenesis. J Transl Med. 2019;17(1):84.
   PubMedGoogle Scholar
• Meyer O. Role of TNF-alpha and cytokines in the physiopathology of rheumatoid arthritis. Therapeutic perspectives. Bull Acad Natl Med. 2003;187(5):935–954. PMID:14979058.
   PubMed Web of Science ®Google Scholar
• Chang YJ, Hsu SL, Liu YT, et al. Gallic acid induces necroptosis via TNF–α signaling pathway in activated hepatic stellate cells. PLoS One. 2015;10((3):e0120713. doi:10.1371/journal.pone.0120713.
   PubMed Web of Science ®Google Scholar
• Berghe TV, Linkermann A, Jouan-Lanhouet S, et al. Regulated necrosis: the expanding network of non-apoptotic cell death pathways. Nat Rev Mol Cell Biol. 2014;15(2):135–147.
   PubMed Web of Science ®Google Scholar
• Andersson U, Harris HE. The role of HMGB1 in the pathogenesis of rheumatic disease. Biochim Biophys Acta Gene Regul Mech. 2010;1799(1-2):141–148. doi:10.1016/j.bbagrm.2009.11.003.
   Web of Science ®Google Scholar
• Xu Z, Jin Y, Yan H, et al. High-mobility group box 1 protein-mediated necroptosis contributes to dasatinib-induced cardiotoxicity. Toxicol Lett. 2018;296:39–47. doi:10.1016/j.toxlet.2018.08.003.
   PubMed Web of Science ®Google Scholar
• Andersson U, Erlandsson-Harris H. HMGB1 is a potent trigger of arthritis. J Intern Med. 2004;255(3):344–350. doi:10.1111/j.1365-2796.2003.01303.x.
   PubMed Web of Science ®Google Scholar
• Basok BI, Kucur M, Kizilgul M, et al. Increased Chitotriosidase activities in patients with rheumatoid arthritis: a possible novel marker? J Med Biochem. 2014;33(3):245–251. doi:10.2478/jomb-2014-0010.
   Web of Science ®Google Scholar
• Arhire LI, Mihalache L, Covasa M. Irisin: a hope in understanding and managing obesity and metabolic syndrome. Front Endocrinol (Lausanne). 2019;10:524.
   PubMed Web of Science ®Google Scholar
• Lavrova DP, Zavodovsky BV, Akhverdyan YR, et al. Irisin as a new marker for the early diagnosis of low-traumatic fractures in rheumatoid arthritis. Klin Lab Diagn. 2018;63(11):702–706.
   PubMedGoogle Scholar
• Vadalà G. Cross talk between muscle and cartilage: the myokine irisin attenuates osteoarthritis related cartilage degeneration. Orthop Proc. 2018;100(SUPP_15):18–18.
   Google Scholar
• Dong J, Dong Y, Chen F, et al. Inhibition of myostatin in mice improves insulin sensitivity via irisin-mediated cross talk between muscle and adipose tissues. Int J Obes. 2016;40(3):434.
   PubMed Web of Science ®Google Scholar
• Mazur-Bialy AI. Irisin acts as a regulator of macrophages host defense. Life Sci. 2017;176:21–25.
   PubMed Web of Science ®Google Scholar
• Gannon NP, Vaughan RA, Garcia-Smith R, et al. Effects of the exercise-inducible myokine irisin on malignant and non-malignant breast epithelial cell behavior in vitro. Int J Cancer. 2015;136(4):E197–E202.
   PubMed Web of Science ®Google Scholar
• Mazur-Bialy AI, Pocheć E, Zarawski M. Anti-inflammatory properties of irisin, mediator of physical activity, are connected with TLR4/MyD88 signaling pathway activation. Int J Mol Sci. 2017;18(4):701.
   PubMed Web of Science ®Google Scholar
• Fan X, Du J, Wang MH, et al. Irisin contributes to the hepatoprotection of dexmedetomidine during intestinal ischemia/reperfusion. Oxid Med Cell Longev. 2019 May 2;2019:7857082. doi:10.1155/2019/7857082.
   PubMed Web of Science ®Google Scholar
• Olson CM, Hedrick MN, Izadi H, et al. P38 mitogen-activated protein kinase controls NF-κB transcriptional activation and tumor necrosis factor alpha production through RelA phosphorylation mediated by mitogen-and stress-activated protein kinase 1 in response to borrelia burgdorferi antigens. Infect Immun. 2007;75(1):270–277.
   PubMed Web of Science ®Google Scholar
• Mazur-Bialy AI, Kozlowska K, Pochec E, et al. Myokine irisin-induced protection against oxidative stress in vitro. Involvement of heme oxygenase-1 and antioxidazing enzymes superoxide dismutase-2 and glutathione peroxidase. J Physiol Pharmacol. 2018;69:117–125.
   PubMed Web of Science ®Google Scholar
• Zhu D, Wang H, Zhang J, et al. Irisin improves endothelial function in type 2 diabetes through reducing oxidative/nitrative stresses. J Mol Cell Cardiol. 2015;87:138–147.
   PubMed Web of Science ®Google Scholar
• Lim MA, Louie B, Ford D, et al. Development of the digital arthritis index. A novel metric to measure disease parameters in rat model of rheumatoid arthritis. Front Pharmacol. 2017;8:818.
   PubMed Web of Science ®Google Scholar