The neural basis of mood dysregulation in bipolar disorder

REFERENCES

• Ali , SO , Denicoff , KD , Altshuler , LL , Hauser , P , Li , X , Conrad , AJ , Smith‐Jackson , EE , Leverich , GS and Post , RM . (2001) . Relationship between prior course of illness and neuroanatomic structures in bipolar disorder: A preliminary study. . Neuropsychiatry, Neuropsychology, and Behavioral Neurology , 14 : 227 – 232 .
   PubMedGoogle Scholar
• Altshuler , LL , Bartzokis , G , Grieder , T , Curran , J and Mintz , J . (1998) . Amygdala enlargement in bipolar disorder and hippocampal reduction in schizophrenia: An MRI study demonstrating neuroanatomic specificity. . Archives of General Psychiatry , 55 : 663 – 664 .
   PubMed Web of Science ®Google Scholar
• Ananth , J , Gold , J and Ghadirian , AM . (1981) . Long term effects of lithium carbonate on cognitive functions. . Journal of Psychiatric Evaluation and Treatment , 3 : 551 – 555 .
   Google Scholar
• Angst , F , Stassen , HH , Clayton , PJ and Angst , J . (2002) . Mortality of patients with mood disorders: Follow‐up over 34–38 years. . Journal of Affective Disorders , 68 : 167 – 181 .
   PubMed Web of Science ®Google Scholar
• Aylward , EH , Roberts‐Twillie , JV , Barta , PE , Kumar , AJ , Harris , GJ , Geer , M , Peyser , CE and Pearlson , GD . (1994) . Basal ganglia volumes and white matter hyperintensities in patients with bipolar disorder. . American Journal of Psychiatry , 151 : 687 – 693 .
   PubMed Web of Science ®Google Scholar
• Baxter , LR, Jr. , Phelps , ME , Mazziotta , JC , Schwartz , JM , Gerner , RH , Selin , CE and Sumida , RM . (1985) . Cerebral metabolic rates for glucose in mood disorders. Studies with positron emission tomography and fluorodeoxyglucose F 18. . Archives of General Psychiatry , 42 : 441 – 447 .
   PubMed Web of Science ®Google Scholar
• Baxter , LR, Jr. , Schwartz , JM , Phelps , ME , Mazziotta , JC , Guze , BH , Selin , CE , Gerner , RH and Sumida , RM . (1989) . Reduction of prefrontal cortex glucose metabolism common to three types of depression. . Archives of General Psychiatry , 46 : 243 – 250 .
   PubMed Web of Science ®Google Scholar
• Bench , CJ , Friston , KJ , Brown , RG , Frackowiak , RS and Dolan , RJ . (1993) . Regional cerebral blood flow in depression measured by positron emission tomography: The relationship with clinical dimensions. . Psychological Medicine , 23 : 579 – 590 .
   PubMed Web of Science ®Google Scholar
• Berns , GS , Martin , M and Proper , SM . (2002) . Limbic hyperreactivity in bipolar II disorder. . American Journal of Psychiatry , 159 : 304 – 306 .
   PubMed Web of Science ®Google Scholar
• Bhagwagar , Z , Cowen , PJ , Goodwin , GM and Harmer , CJ . (2004) . Normalization of enhanced fear recognition by acute SSRI treatment in subjects with a previous history of depression. . American Journal of Psychiatry , 161 : 166 – 168 .
   PubMed Web of Science ®Google Scholar
• Blumberg , HP , Leung , HC , Skudlarski , P , Lacadie , CM , Fredericks , CA , Harris , BC , Charney , DS , Gore , JC , Krystal , JH and Peterson , BS . (2003a) . A functional magnetic resonance imaging study of bipolar disorder: State‐ and trait‐related dysfunction in ventral prefrontal cortices. . Archives of General Psychiatry , 60 : 601 – 609 .
   PubMed Web of Science ®Google Scholar
• Blumberg , HP , Martin , A , Kaufman , J , Leung , HC , Skudlarski , P , Lacadie , C , Fulbright , RK , Gore , JC , Charney , DS , Krystal , JH and Peterson , BS . (2003b) . Frontostriatal abnormalities in adolescents with bipolar disorder: Preliminary observations from functional MRI. . American Journal of Psychiatry , 160 : 1345 – 1347 .
   PubMed Web of Science ®Google Scholar
• Blumberg , HP , Stern , E , Ricketts , S , Martinez , D , de Asis , J , White , T , Epstein , J , Isenberg , N , McBride , PA , Kemperman , I , Emmerich , S , Dhawan , V , Eidelberg , D , Kocsis , JH and Silbersweig , DA . (1999) . Rostral and orbital prefrontal cortex dysfunction in the manic state of bipolar disorder. . American Journal of Psychiatry , 156 : 1986 – 1988 .
   PubMed Web of Science ®Google Scholar
• Blumberg , HP , Stern , E , Martinez , D , Ricketts , S , de Asis , J , White , T , Epstein , J , McBride , PA , Eidelberg , D , Kocsis , JH and Silbersweig , DA . (2000) . Increased anterior cingulate and caudate activity in bipolar mania. . Biological Psychiatry , 48 : 1045 – 1052 .
   PubMed Web of Science ®Google Scholar
• Brambilla , P , Harenski , K , Nicoletti , M , Mallinger , AG , Frank , E , Kupfer , DJ , Keshavan , MS and Soares , JC . (2001) . Differential effects of age on brain gray matter in bipolar patients and healthy individuals. . Neuropsychobiology , 43 : 242 – 247 .
   PubMed Web of Science ®Google Scholar
• Brambilla , P , Harenski , K , Nicoletti , M , Sassi , RB , Mallinger , AG , Frank , E , Kupfer , DJ , Keshavan , MS and Soares , JC . (2003) . MRI investigation of temporal lobe structures in bipolar patients. . Journal of Psychiatric Research , 37 : 287 – 295 .
   PubMed Web of Science ®Google Scholar
• Brambilla , P , Nicoletti , MA , Harenski , K , Sassi , RB , Mallinger , AG , Frank , E , Kupfer , DJ , Keshavan , MS and Soares , JC . (2002) . Anatomical MRI study of subgenual prefrontal cortex in bipolar and unipolar subjects. . Neuropsychopharmacology , 27 : 792 – 799 .
   PubMed Web of Science ®Google Scholar
• Brody , AL , Saxena , S , Stoessel , P , Gillies , LA , Fairbanks , LA , Alborzian , S , Phelps , ME , Huang , SC , Wu , HM , Ho , ML , Ho , MK , Au , SC , Maidment , K and Baxter , LR, Jr. (2001) . Regional brain metabolic changes in patients with major depression treated with either paroxetine or interpersonal therapy: Preliminary findings. . Archives of General Psychiatry , 58 : 631 – 640 .
   PubMed Web of Science ®Google Scholar
• Calder , AJ , Lawrence , AD and Young , AW . (2001) . Neuropsychology of fear and loathing. Nature Reviews. . Neuroscience , 2 : 352 – 363 .
   PubMed Web of Science ®Google Scholar
• Caligiuri , MP , Brown , GG , Meloy , MJ , Eberson , SC , Kindermann , SS , Frank , LR , Zorrilla , LE and Lohr , JB . (2003) . An fMRI study of affective state and medication on cortical and subcortical brain regions during motor performance in bipolar disorder. . Psychiatry Research , 123 : 171 – 182 .
   PubMed Web of Science ®Google Scholar
• Cavanagh , JT , Van Beck , M , Muir , W and Blackwood , DH . (2002) . Case‐control study of neurocognitive function in euthymic patients with bipolar disorder: An association with mania. . British Journal of Psychiatry , 180 : 320 – 326 .
   PubMed Web of Science ®Google Scholar
• Clark , L , Iversen , SD and Goodwin , GM . (2002) . Sustained attention deficit in bipolar disorder. . British Journal of Psychiatry , 180 : 313 – 319 .
   PubMed Web of Science ®Google Scholar
• Darwin C (1998) The expression of the emotions in man and animals (3rd ed.). London: Harper Collins. (Original work published 1872)
   Google Scholar
• Davidson , RJ , Jackson , DC and Kalin , NH . (2000) . Emotion, plasticity, context, and regulation: Perspectives from affective neuroscience. . Psychological Bulletin , 126 : 890 – 909 .
   PubMed Web of Science ®Google Scholar
• Devinsky , O . (1995) . Cognitive and behavioral effects of antiepileptic drugs. . Epilepsia , 36 (Suppl. 2) : S46 – S65 .
   Google Scholar
• Elliott , R , Ogilvie , A , Rubinsztein , JS , Calderon , G , Dolan , RJ and Sahakian , BJ . (2004) . Abnormal ventral frontal response during performance of an affective go/no go task in patients with mania. . Biological Psychiatry , 55 : 1163 – 1170 .
   PubMed Web of Science ®Google Scholar
• Elliott , R , Rubinsztein , JS , Sahakian , BJ and Dolan , RJ . (2002) . The neural basis of mood‐congruent processing biases in depression. . Archives of General Psychiatry , 59 : 597 – 604 .
   PubMed Web of Science ®Google Scholar
• Engelsmann , F , Katz , J , Ghadirian , AM and Schachter , D . (1988) . Lithium and memory: A long‐term follow‐up study. . Journal of Clinical Psychopharmacology , 8 : 207 – 212 .
   PubMed Web of Science ®Google Scholar
• Ferrier , IN , Stanton , BR , Kelly , TP and Scott , J . (1999) . Neuropsychological function in euthymic patients with bipolar disorder. . British Journal of Psychiatry , 175 : 246 – 251 .
   PubMed Web of Science ®Google Scholar
• Getz , GE , Shear , PK and Strakowski , SM . (2003) . Facial affect recognition deficits in bipolar disorder. . Journal of International Neuropsychological Society , 9 : 623 – 632 .
   PubMed Web of Science ®Google Scholar
• Gitlin , MJ , Swendsen , J , Heller , TL and Hammen , C . (1995) . Relapse and impairment in bipolar disorder. . American Journal of Psychiatry , 152 : 1635 – 1640 .
   PubMed Web of Science ®Google Scholar
• Goldapple , K , Segal , Z , Garson , C , Lau , M , Bieling , P , Kennedy , S and Mayberg , H . (2004) . Modulation of cortical‐limbic pathways in major depression: Treatment‐specific effects of cognitive behavior therapy. . Archives of General Psychiatry , 61 : 34 – 41 .
   PubMed Web of Science ®Google Scholar
• Goodwin , GM , Austin , MP , Dougall , N , Ross , M , Murray , C , O'Carroll , RE , Moffoot , A , Prentice , N and Ebmeier , KP . (1993) . State changes in brain activity shown by the uptake of 99mTc‐exametazime with single photon emission tomography in major depression before and after treatment. . Journal of Affective Disorders , 29 : 243 – 253 .
   PubMed Web of Science ®Google Scholar
• Goodwin , GM , Cavanagh , JT , Glabus , MF , Kehoe , RF , O'Carroll , RE and Ebmeier , KP . (1997) . Uptake of 99mTc‐exametazime shown by single photon emission computed tomography before and after lithium withdrawal in bipolar patients: Associations with mania. . British Journal of Psychiatry , 170 : 426 – 430 .
   PubMed Web of Science ®Google Scholar
• Gross , JJ . (2002) . Emotion regulation: Affective, cognitive, and social consequences. . Psychophysiology , 39 : 281 – 291 .
   PubMed Web of Science ®Google Scholar
• Gruber , SA , Rogowska , J and Yurgelun‐Todd , DA . (2004) . Decreased activation of the anterior cingulate in bipolar patients: an fMRI study. . Journal of Affective Disorders , 82 : 191 – 201 .
   PubMed Web of Science ®Google Scholar
• Gur , RE , McGrath , C , Chan , RM , Schroeder , L , Turner , T , Turetsky , BI , Kohler , C , Alsop , D , Maldjian , J , Ragland , JD and Gur , RC . (2002) . An fMRI study of facial emotion processing in patients with schizophrenia. . American Journal of Psychiatry , 159 : 1992 – 1999 .
   PubMed Web of Science ®Google Scholar
• Hariri , AR , Mattay , VS , Tessitore , A , Fera , F and Weinberger , DR . (2003) . Neocortical modulation of the amygdala response to fearful stimuli. . Biological Psychiatry , 53 : 494 – 501 .
   PubMed Web of Science ®Google Scholar
• Harmer , CJ , Grayson , L and Goodwin , GM . (2002) . Enhanced recognition of disgust in bipolar illness. . Biological Psychiatry , 51 : 298 – 304 .
   PubMed Web of Science ®Google Scholar
• Harrison , PJ . (2002) . The neuropathology of primary mood disorder. . Brain , 125 : 1428 – 1449 .
   PubMed Web of Science ®Google Scholar
• Hempel , A , Hempel , E , Schonknecht , P , Stippich , C and Schroder , J . (2003) . Impairment in basal limbic function in schizophrenia during affect recognition. . Journal of Psychiatric Research , 122 : 115 – 124 .
   Google Scholar
• Keck , PE, Jr. , McElroy , SL , Strakowski , SM , West , SA , Sax , KW , Hawkins , JM , Bourne , ML and Haggard , P . (1998) . 12‐month outcome of patients with bipolar disorder following hospitalization for a manic or mixed episode. . American Journal of Psychiatry , 155 : 646 – 652 .
   PubMed Web of Science ®Google Scholar
• Keedwell , P , Andrew , C , Williams , SCR , Brammer , M and Phillips , ML . (2005) . Abnormal ventromedial prefrontal cortical and subcortical responses to happy stimuli are associated with anhedonia and state anxiety in major depressive disorder. . Biological Psychiatry , 58 : 495 – 503 .
   PubMed Web of Science ®Google Scholar
• Kennedy , SH , Evans , KR , Kruger , S , Mayberg , HS , Meyer , JH , McCann , S , Arifuzzman , AI , Houle , S and Vaccarino , FJ . (2001) . Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression. . American Journal of Psychiatry , 158 : 899 – 905 .
   PubMed Web of Science ®Google Scholar
• Kessing , LV . (1998) . Cognitive impairment in the euthymic phase of affective disorder. . Psychological Medicine , 28 : 1027 – 1038 .
   PubMed Web of Science ®Google Scholar
• Kessler , RC , McGonagle , KA , Zhao , S , Nelson , CB , Hughes , M , Eshleman , S , Wittchen , HU and Kendler , KS . (1994) . Lifetime and 12‐month prevalence of DSM‐III‐R psychiatric disorders in the United States: Results from the National Comorbidity Survey. . Archives of General Psychiatry , 51 : 8 – 19 .
   PubMed Web of Science ®Google Scholar
• Ketter , TA , Kimbrell , TA , George , MS , Dunn , RT , Speer , AM , Benson , BE , Willis , MW , Danielson , A , Frye , MA , Herscovitch , P and Post , RM . (2001) . Effects of mood and subtype on cerebral glucose metabolism in treatment‐resistant bipolar disorder. . Biological Psychiatry , 49 : 97 – 109 .
   PubMed Web of Science ®Google Scholar
• King , DJ . (1994) . Psychomotor impairment and cognitive disturbances induced by neuroleptics. . Acta Psychiatrica Scandinavica , 380 (Suppl.) : 53 – 58 .
   Google Scholar
• Kocsis , JH , Shaw , ED , Stokes , PE , Wilner , P , Elliot , AS , Sikes , C , Myers , B , Manevitz , A and Parides , M . (1993) . Neuropsychologic effects of lithium discontinuation. . Journal of Clinical Psychopharmacology , 13 : 268 – 275 .
   PubMed Web of Science ®Google Scholar
• Kruger , S , Seminowicz , D , Goldapple , K , Kennedy , SH and Mayberg , HS . (2003) . State and trait influences on mood regulation in bipolar disorder: Blood flow differences with an acute mood challenge. . Biological Psychiatry , 54 : 1274 – 1283 .
   PubMed Web of Science ®Google Scholar
• Lang PJ Bradley MM Cuthbert BN (1998) International affective picture system (IAPS). NIMH Center for the Study of Emotion and Attention, University of Florida, Gaines‐ville.
   Google Scholar
• Lange , K , Williams , LM , Young , AW , Bullmore , ET , Brammer , MJ , Williams , SC , Gray , JA and Phillips , ML . (2003) . Task instructions modulate neural responses to fearful facial expressions. . Biological Psychiatry , 53 : 226 – 232 .
   PubMed Web of Science ®Google Scholar
• Lawrence , NS , Williams , AM , Surguladze , S , Giampietro , V , Brammer , MJ , Andrew , C , Frangou , S , Ecker , C and Phillips , ML . (2004) . Subcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression. . Biological Psychiatry , 55 : 578 – 587 .
   PubMed Web of Science ®Google Scholar
• Lembke , A and Ketter , TA . (2002) . Impaired recognition of facial emotion in mania. . American Journal of Psychiatry , 159 : 302 – 304 .
   PubMed Web of Science ®Google Scholar
• Lennox , BR , Jacob , R , Calder , AJ , Lupson , V and Bullmore , ET . (2004) . Behavioural and neurocognitive responses to sad facial affect are attenuated in patients with mania. . Psychological Medicine , 34 : 795 – 802 .
   PubMed Web of Science ®Google Scholar
• Levesque , J , Eugene , F , Joanette , Y , Paquette , V , Mensour , B , Beaudoin , G , Leroux , JM , Bourgouin , P and Beauregard , M . (2003) . Neural circuitry underlying voluntary suppression of sadness. . Biological Psychiatry , 53 : 502 – 510 .
   PubMed Web of Science ®Google Scholar
• Lochhead , RA , Parsey , RV , Oquendo , MA and Mann , JJ . (2004) . Regional brain gray matter volume differences in patients with bipolar disorder as assessed by optimized voxel‐based morphometry. . Biological Psychiatry , 55 : 1154 – 1162 .
   PubMed Web of Science ®Google Scholar
• Lopez‐Larson , MP , DelBello , MP , Zimmerman , ME , Schwiers , ML and Strakowski , SM . (2002) . Regional prefrontal gray and white matter abnormalities in bipolar disorder. . Biological Psychiatry , 52 : 93 – 100 .
   PubMed Web of Science ®Google Scholar
• Lyon , HM , Startup , M and Bentall , RP . (1999) . Social cognition and the manic defense: Attributions, selective attention, and self‐schema in bipolar affective disorder. . Journal of Abnormal Psychology , 108 : 273 – 282 .
   PubMed Web of Science ®Google Scholar
• Malhi , GS , Lagopoulos , J , Sachdev , P , Mitchell , PB , Ivanovski , B and Parker , GB . (2004a) . Cognitive generation of affect in hypomania: An fMRI study. . Bipolar Disorders , 6 : 271 – 285 .
   PubMed Web of Science ®Google Scholar
• Malhi , GS , Lagopoulos , J , Ward , PB , Kumari , V , Mitchell , PB , Parker , GB , Ivanovski , B and Sachdev , P . (2004b) . Cognitive generation of affect in bipolar depression: An fMRI study. . European Journal of Neuroscience , 19 : 741 – 754 .
   PubMed Web of Science ®Google Scholar
• Manji , HK , Moore , GJ and Chen , G . (2000) . Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: Implications for the pathophysiology and treatment of manic‐depressive illness. . Biological Psychiatry , 48 : 740 – 754 .
   PubMed Web of Science ®Google Scholar
• Martin , SD , Martin , E , Rai , SS , Richardson , MA and Royall , R . (2001) . Brain blood flow changes in depressed patients treated with interpersonal psychotherapy or venlafaxine hydrochloride: preliminary findings. . Archives of General Psychiatry , 58 : 641 – 648 .
   PubMed Web of Science ®Google Scholar
• Martinez‐Aran , A , Penades , R , Vieta , E , Colom , F , Reinares , M , Benabarre , A , Salamero , M and Gasto , C . (2002) . Executive function in patients with remitted bipolar disorder and schizophrenia and its relationship with functional outcome. . Psychotherapy and Psychosomatics , 71 : 39 – 46 .
   PubMed Web of Science ®Google Scholar
• Martinez‐Aran , A , Vieta , E , Colom , F , Torrent , C , Sanchez‐Moreno , J , Reinares , M , Benabarre , A , Goikolea , JM , Brugue , E , Daban , C and Salamero , M . (2004a) . Cognitive impairment in euthymic bipolar patients: Implications for clinical and functional outcome. . Bipolar Disorders , 6 : 224 – 232 .
   PubMed Web of Science ®Google Scholar
• Martinez‐Aran , A , Vieta , E , Reinares , M , Colom , F , Torrent , C , Sanchez‐Moreno , J , Benabarre , A , Goikolea , JM , Comes , M and Salamero , M . (2004b) . Cognitive function across manic or hypomanic, depressed, and euthymic states in bipolar disorder. . American Journal of Psychiatry , 161 : 262 – 270 .
   PubMed Web of Science ®Google Scholar
• Martinot , JL , Hardy , P , Feline , A , Huret , JD , Mazoyer , B , Attar‐Levy , D , Pappata , S and Syrota , A . (1990) . Left prefrontal glucose hypometabolism in the depressed state: A confirmation. . American Journal of Psychiatry , 147 : 1313 – 1317 .
   PubMed Web of Science ®Google Scholar
• Mataix‐Cols , D , Cullen , S , Lange , K , Zelaya , F , Andrew , C , Amaro , E , Brammer , MJ , Williams , SC , Speckens , A and Phillips , ML . (2003) . Neural correlates of anxiety associated with obsessive‐compulsive symptom dimensions in normal volunteers. . Biological Psychiatry , 53 : 482 – 493 .
   PubMed Web of Science ®Google Scholar
• Mayberg , HS , Brannan , SK , Tekell , JL , Silva , JA , Mahurin , RK , McGinnis , S and Jerabek , PA . (2000) . Regional metabolic effects of fluoxetine in major depression: Serial changes and relationship to clinical response. . Biological Psychiatry , 48 : 830 – 843 .
   PubMed Web of Science ®Google Scholar
• Mayberg , HS , Liotti , M , Brannan , SK , McGinnis , S , Mahurin , RK , Jerabek , PA , Silva , JA , Tekell , JL , Matin , CC , Lancaster , JL and Fox , PT . (1999) . Reciprocal limbic‐cortical function and negative mood: Converging PET findings in depression and normal sadness. . American Journal of Psychiatry , 156 : 675 – 682 .
   PubMed Web of Science ®Google Scholar
• McClure , EB , Pope , K , Hoberman , AJ , Pine , DS and Leibenluft , E . (2003) . Facial expression recognition in adolescents with mood and anxiety disorders. . American Journal of Psychiatry , 160 : 1172 – 1174 .
   PubMed Web of Science ®Google Scholar
• McDonald , C , Zanelli , J , Rabe‐Hesketh , S , Ellison‐Wright , I , Sham , P , Kalidindi , S , Murray , RM and Kennedy , N . (2004) . Meta‐analysis of magnetic resonance imaging brain morphometry studies in bipolar disorder. . Biological Psychiatry , 56 : 411 – 417 .
   PubMed Web of Science ®Google Scholar
• Mehta , MA , Sahakian , BJ , McKenna , PJ and Robbins , TW . (1999) . Systemic sulpiride in young adult volunteers simulates the profile of cognitive deficits in Parkinson's disease. . Psychopharmacology (Berlin) , 146 : 162 – 174 .
   PubMed Web of Science ®Google Scholar
• Moore , PB , Shepherd , DJ , Eccleston , D , Macmillan , IC , Goswami , U , McAllister , VL and Ferrier , IN . (2001) . Cerebral white matter lesions in bipolar affective disorder: Relationship to outcome. . British Journal of Psychiatry , 178 : 172 – 176 .
   PubMed Web of Science ®Google Scholar
• Morris , JS , Frith , CD , Perrett , DI , Rowland , D , Young , AW , Calder , AJ and Dolan , RJ . (1996) . A differential neural response in the human amygdala to fearful and happy facial expressions. . Nature , 383 : 812 – 815 .
   PubMed Web of Science ®Google Scholar
• Murphy , FC , Sahakian , BJ , Rubinsztein , JS , Michael , A , Rogers , RD , Robbins , TW and Paykel , ES . (1999) . Emotional bias and inhibitory control processes in mania and depression. . Psychological Medicine , 29 : 1307 – 1321 .
   PubMed Web of Science ®Google Scholar
• O'Connell , RA , Mayo , JA , Flatow , L , Cuthbertson , B and O'Brien , BE . (1991) . Outcome of bipolar disorder on long‐term treatment with lithium. . British Journal of Psychiatry , 159 : 123 – 129 .
   PubMed Web of Science ®Google Scholar
• Ochsner , KN , Bunge , SA , Gross , JJ and Gabrieli , JD . (2002) . Rethinking feelings: An FMRI study of the cognitive regulation of emotion. . Journal of Cognitive Neuroscience , 14 : 1215 – 1229 .
   PubMed Web of Science ®Google Scholar
• Phillips , ML , Drevets , WC , Rauch , SL and Lane , R . (2003a) . Neurobiology of emotion perception: I. The neural basis of normal emotion perception. . Biological Psychiatry , 54 : 504 – 514 .
   PubMed Web of Science ®Google Scholar
• Phillips , ML , Drevets , WC , Rauch , SL and Lane , R . (2003b) . Neurobiology of emotion perception: II. Implications for major psychiatric disorders. . Biological Psychiatry , 54 : 515 – 528 .
   PubMed Web of Science ®Google Scholar
• Phillips , ML , Marks , IM , Senior , C , Lythgoe , D , O'Dwyer , AM , Meehan , O , Williams , SC , Brammer , MJ , Bullmore , ET and McGuire , PK . (2000) . A differential neural response in obsessive‐compulsive disorder patients with washing compared with checking symptoms to disgust. . Psychological Medicine , 30 : 1037 – 1050 .
   PubMed Web of Science ®Google Scholar
• Phillips , ML , Williams , L , Senior , C , Bullmore , ET , Brammer , MJ , Andrew , C , Williams , SC and David , AS . (1999) . A differential neural response to threatening and non‐threatening negative facial expressions in paranoid and non‐paranoid schizophrenics. . Psychiatry Research , 92 : 11 – 31 .
   PubMed Web of Science ®Google Scholar
• Phillips , ML , Young , AW , Senior , C , Brammer , M , Andrew , C , Calder , AJ , Bullmore , ET , Perrett , DI , Rowland , D , Williams , SC , Gray , JA and David , AS . (1997) . A specific neural substrate for perceiving facial expressions of disgust. . Nature , 389 : 495 – 498 .
   PubMed Web of Science ®Google Scholar
• Rubinsztein , JS , Fletcher , PC , Rogers , RD , Ho , LW , Aigbirhio , FI , Paykel , ES , Robbins , TW and Sahakian , BJ . (2001) . Decision‐making in mania: A PET study. . Brain , 124 : 2550 – 2563 .
   PubMed Web of Science ®Google Scholar
• Sassi , RB , Brambilla , P , Hatch , JP , Nicoletti , MA , Mallinger , AG , Frank , E , Kupfer , DJ , Keshavan , MS and Soares , JC . (2004) . Reduced left anterior cingulate volumes in untreated bipolar patients. . Biological Psychiatry , 56 : 467 – 475 .
   PubMed Web of Science ®Google Scholar
• Sax , KW , Strakowski , SM , Zimmerman , ME , DelBello , MP , Keck , PE, Jr. and Hawkins , JM . (1999) . Frontosubcortical neuroanatomy and the continuous performance test in mania. . American Journal of Psychiatry , 156 : 139 – 141 .
   PubMed Web of Science ®Google Scholar
• Sharma , V , Menon , R , Carr , TJ , Densmore , M , Mazmanian , D and Williamson , PC . (2003) . An MRI study of subgenual prefrontal cortex in patients with familial and non‐familial bipolar I disorder. . Journal of Affective Disorders , 77 : 167 – 171 .
   PubMed Web of Science ®Google Scholar
• Silfverskiold , P and Risberg , J . (1989) . Regional cerebral blood flow in depression and mania. . Archives of General Psychiatry , 46 : 253 – 259 .
   PubMed Web of Science ®Google Scholar
• Sprengelmeyer , R , Rausch , M , Eysel , UT and Przuntek , H . (1998) . Neural structures associated with recognition of facial expressions of basic emotions. . Procceedings of the Royal Society of London. Series B , 265 : 1927 – 1931 .
   PubMed Web of Science ®Google Scholar
• Strakowski , SM , Adler , CM and DelBello , MP . (2002) . Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder? . Bipolar Disorders , 4 : 80 – 88 .
   PubMed Web of Science ®Google Scholar
• Strakowski , SM , Adler , CM , Holland , SK , Mills , N and DelBello , MP . (2004) . A preliminary FMRI study of sustained attention in euthymic, unmedicated bipolar disorder. . Neuropsychopharmacology , 29 : 1734 – 1740 .
   PubMed Web of Science ®Google Scholar
• Strakowski , SM , DelBello , MP , Sax , KW , Zimmerman , ME , Shear , PK , Hawkins , JM and Larson , ER . (1999) . Brain magnetic resonance imaging of structural abnormalities in bipolar disorder. . Archives of General Psychiatry , 56 : 254 – 260 .
   PubMed Web of Science ®Google Scholar
• Surguladze , SA , Brammer , MJ , Young , AW , Andrew , C , Travis , MJ , Williams , SC and Phillips , ML . (2003) . A preferential increase in the extrastriate response to signals of danger. . NeuroImage , 19 : 1317 – 1328 .
   PubMed Web of Science ®Google Scholar
• Thompson , PJ . (1991) . Antidepressants and Memory. . Annual Review of Psychopharmacology , 6 : 79 – 90 .
   Web of Science ®Google Scholar
• Tohen , M , Hennen , J , Zarate , CM, Jr. , Baldessarini , RJ , Strakowski , SM , Stoll , AL , Faedda , GL , Suppes , T , Gebre‐Medhin , P and Cohen , BM . (2000) . Two‐year syndromal and functional recovery in 219 cases of first‐episode major affective disorder with psychotic features. . American Journal of Psychiatry , 157 : 220 – 228 .
   PubMed Web of Science ®Google Scholar
• Venn , HR , Gray , JM , Montagne , B , Murray , LK , Michael , Burt D , Frigerio , E , Perrett , DI and Young , AH . (2004) . Perception of facial expressions of emotion in bipolar disorder. . Bipolar Disorder , 6 : 186 – 293 .
   Web of Science ®Google Scholar
• Videbech , P and Ravnkilde , B . (2004) . Hippocampal volume and depression: a meta‐analysis of MRI studies. . American Journal of Psychiatry , 161 : 1957 – 1966 .
   PubMed Web of Science ®Google Scholar
• Williams , LM , Das , P , Harris , AW , Liddell , BB , Brammer , MJ , Olivieri , G , Skerrett , D , Phillips , ML , David , AS , Peduto , A and Gordon , E . (2004) . Dysregulation of arousal and amygdala‐prefrontal systems in paranoid schizophrenia. . American Journal of Psychiatry , 161 : 480 – 489 .
   PubMed Web of Science ®Google Scholar
• Yurgelun‐Todd , DA , Gruber , SA , Kanayama , G , Killgore , WD , Baird , AA and Young , AD . (2000) . fMRI during affect discrimination in bipolar affective disorder. . Bipolar Disorders , 2 : 237 – 248 .
   PubMed Web of Science ®Google Scholar
• Zubieta , JK , Huguelet , P , O'Neil , RL and Giordani , BJ . (2001) . Cognitive function in euthymic bipolar I disorder. . Psychiatry Research , 102 : 9 – 20 .
   PubMed Web of Science ®Google Scholar