Advanced search
Publication Cover
Biomarkers Volume 7, 2002 - Issue 6
Submit an article Journal homepage
27
Views
24
CrossRef citations to date
0
Altmetric
Research Article

Toxicity of cypermethrin: hsp70 as a biomarker of response in transgenic Drosophila

Indranil Mukhopadhyay Embryotoxicology Section, Industrial Toxicology Research Centre, PO Box 80, M. G. Marg, Lucknow 226 001, Uttar Pradesh, India
,
Aamir Nazir Embryotoxicology Section, Industrial Toxicology Research Centre, PO Box 80, M. G. Marg, Lucknow 226 001, Uttar Pradesh, India
,
D. K. Saxena Embryotoxicology Section, Industrial Toxicology Research Centre, PO Box 80, M. G. Marg, Lucknow 226 001, Uttar Pradesh, India
&
D. Kar Chowdhuri Embryotoxicology Section, Industrial Toxicology Research Centre, PO Box 80, M. G. Marg, Lucknow 226 001, Uttar Pradesh, India
Pages 501-510 | Published online: 29 Sep 2008

  • ABASSY, M. A., ELDEERAWI, M. E. and ELDEFRAWI, A. T. 1983, Pyrethroid action on nicotinic acetylcholine receptor/channel. Pesticide Biochemistry and Physiolgy, 19, 299-308.
  • BARNES, J. A., DIX, D. J., COLLINS, B. W., LUFT, C. and ALLEN, J. W. 2001, Expression of inducible Hsp70 enhances the proliferation of MCF-7 breast cancer cells and protects against the cytotoxic effects of hyperthermia. Cell Stress and Chaperanes, 6, 316-325.
  • BENFORD, D. J., HANLEY, B. A., BOTTRILL, K., OEHLSCHLAGER, S., BALLS, M., BRANCE, F., CASTEGNARO, J. J., DESCOTES, J., HEMMINIKI, K., LINDSAY, D. and SCHILTER, B. 2000, Biomarkers as predictive tools in toxicity testing. Alternatives to Laboratory Animals. 28, 119-131.
  • CASIDA, J. E. 1980, Pyrethrum flowers and pyrethroid insecticides. Environmental Health Perspectives, 34, 189-202.
  • CHADDHA, D. S. 1992, Cypermethrin. In Prevention of Food Adulteration Act and Rules, 1952 Amended in 1992, edited by D. S. Chaddha (New Delhi: Associated Chamber of Commerce and Industry of India), pp. 114-127.
  • CHAPPLE, J. P., SMERDON, G. R. and HAWKINS, A. J. S. 1997, Stress-70 protein induction in Mytilus edutis: tissue specific responses to elevated temperature reflect relative vulnerability and physiological function. Journal of Experimental Marine Biology and Ecology, 217, 225-235.
  • CRAIG, E. A., WEISSMAN, J. S. and HORWICH, A. L. 1994, Heat shock proteins and molecular chaperones: mediators of protein conformation and turnover in the cell. Cell, 78, 365-372.
  • DE POMERAI, D. I. 1996, Heat shock proteins as biomarkers of pollution. Human and Experimental Toxicology, 15, 279-285.
  • DILWORTH, C. and TIMBRELL, J. A. 1998, An investigation into the sensitivity of heat shock proteins as markers of cellular damage: a comparative study of hydrazine and cadmium chloride in primary rat hepatocyte cultures. Biomarkers, 3, 177-190.
  • ELLIOTT, M., JAMES, N. F. AND POTTER, C. 1978. The future of pyrethroids in insect control. Annual Review in Entomology, 23, 443-469.
  • FESTING, M. F. W., BAUMANS, V., COMBES, D. R., HALDER, M., HENDRIKSEN, F. M., HOWARD, B. R., LOVELL, D. P., MOORE, G. J., OVEREND, P. and WILSON, M. S. 1998. Reducing the use of laboratory animals in biomedical research: problems and possible solutions. Alternatives to Laboratory Animals, 26, 283-301.
  • HIGHTOWER, L. E. 1991, Heat shock, stress proteins, chaperones and proteotoxicity. Cell, 66, 191-201.
  • KAR CHOWDHURI, D., SAXENA, D. K. and VISWANATHAN, P. N. 1999, Effect of hexachlorohexane (HCH), its isomers and metabolites on Hsp70 expression in transgenic Drosophila melanogaster. Pesticide Biochemistry and Physiology, 63, 15-25.
  • KING, Y. T., LIN, C. S., LIN, J. H. and LEE, W. C. 2002. Whole-body hyperthermia-induced thermotolerance is associated with the induction of heat shock protein 70 in mice. Journal of Experimental Biology, 205, 273-278.
  • KOHLER, H. R., BELITZ, B., ECKWERT, H., ADAM, R., RAHMAN, B. and TRONTELJ, P. 1998, Validation of hsp70 stress gene expression as a marker of metal effects in Deroceras reticulatum (Pulmonata): correlation with demographic parameters. Environmental Toxicology and Chemistry, 17, 2246-2253.
  • KREBS, R. A. and FEDER, M. E. 1997. Tissue specific variation in hsp70 expression and thermal damage in Drosophila melanogaster larve. Journal of Experimental Biology, 200, 2007-2015.
  • LAKHOTIA, S. C. and MUKHERJEE, T. 1980, Specific activation of puff 93D of Drosophila melanogaster by benzamide and the effect of benzamide on the heat shock induced puffing activity. Chromosoma, 81, 125-136.
  • LINDQUIST, S. and CRAIG, E. A. 1988, The heat shock proteins. Annual Review of Genetics, 22, 631-677.
  • LIS, J. T., SIMON, J. A. and SUTTON, C. A. 1983, New heat shock puffs and ß-galactosidase activity resulting from transformation of Drosophila with an hsp 70-lacZ hybrid gene. Cell, 35, 403-413.
  • MORIMOTO, R. I., TISSIERES, A. and GEORGOPOULOS, C. (editor). 1994. The Biology of Heat Shock Proteins and Molecular Chaperones (New York: Cold Spring Harbor Laboratory Press), 610 pp.
  • MUKHOPADHYAY, I., NAZIR, A., MAHMOOD, K., SAXENA, D. K., DAS, M., KHANNA, S. K. and KAR CHOWDHURI, D. 2002, Toxicity of argemone oil: effect on hsp70 expression and tissue damage in transgenic Drosophila melanogaster (hsp 70-lacZ)Bg9. Cell Biology and Toxicology, 18, 1-11.
  • NADEAU, D., CORNEAU, S., PLANTE, I., MORROW, G. and TANGUAY, R. M. 2001, Evaluation for Hsp70 as a biomarker of effect of pollutants on the earthworm Lumbricus terrestris. Cell Stress and Chaperones, 6, 153-163.
  • NAZIR, A., MUKHOPADHYAY, I., SAXENA, D. K. and KAR CHOWDHURI, D. 2001, Chlorpyrifos induced hsp70 expression and effect on reproductive performance in transgenic Drosophila melanogaster (hsp70-lacZ) Bg9. Archives of Environmental Contamination and Toxicology, 41, 443-449.
  • O'KANE, C. J. and GEHRING, W. J. 1987, Detection in situ of genomic regulatory elements in Drosophila. Proceedings of National Academy of Sciences of the USA, 84, 9123-9127.
  • PYZA, E., MAK, P., KRAMARZ, P. and LASKOWSKI, R. 1997, Heat shock proteins (hsp70) as biomarkers in ecotoxicological studies. Ecotoxicology and Environmental Safety, 38, 244-251.
  • RUIGHT, G. S. F. 1985, Pyrethroids. In Comprehensive Insect Physiology, Biochemistry and Pharmacology, vol. 12., edited by G. A. Kerkut and L. I. Gilbert (New York: Pergemon Press), pp. 183-262.
  • RYAN, J. A. and HIGHTOWER, L. E. 1996, Stress proteins as molecular biomarkers for environmental toxicology. In Stress Inducible Cellular Responses, edited by U. Feige, R. I. Morimoto, I. Yahura and B. Polla (Basel: Birkhauser Verlag), pp. 411-424.
  • SAMBROOK, J., FRITSCH, E. F. and MANIATIS, T. (editors). 1989, Molecular Cloning: A Laboratory Manual (Cold Spring Harbor: Cold Spring Harbor Laboratory Press), pp. 18.47-18.75.
  • SINGH, B. N. and LAKHOTIA, S. C. 1995, The non-induction of HSP70 in heat shocked Malpighian tubules of Drosophila larvae is not due to constitutive presence of HSP70 or HSC70. Current Science, 69, 178-182.
  • STRINGHAM, G. and CANDIDO, E. P. M. 1994, Transgenic hsp16-lacZ strains of the soil nematode Caenorhabditis elegans as biological monitors of environmental stress. Environmental Toxicology and Chemistry, 13, 1211-1220.
  • VARO, I., SERRANO, R., PITARCH, E., AMAT, F., LOPEZ, F. J. and NAVARRO, J. C. 2002, Bioaccumulation of chlorpyrifos through an experimental food chain: study of protein HSP70 as biomarker of sub-lethal stress in fish. Archives of Environmental Contamination and Toxicology, 42, 229-235.
  • VELAZQUEZ, J. M. and LINDQUIST, S. 1984, Hsp70: nuclear concentration during environmental stress and cytoplasmic storage during recovery. Cell, 36, 655-662.
  • WELCH, W. J. 1993, How cells respond to stress. Scientific American, 34-41.
  • WERNER, I. and HINTON, D. 1999, Field validation of hsp70 stress proteins as biomarkers in Asian clam (Potamocorbula amurenis): is downregulation an indicator of stress? Biomarkers, 4, 473-484.
  • WERNER, I. and NAGEL, R. 1997, Stress proteins hsp60 and hsp70 in three species of amphipoda exposed to cadmiumm, diazinon, dieldrin and fluornathene. Environmental Toxicology and Chemistry, 16, 2393-2403.
  • WILKINSON, C. F. and BRATTESTEN, L. B. 1972, Microsomal drug metabolizing enzymes in insects. Drug Metabolism Review, 1, 153-177.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.