88
Views
11
CrossRef citations to date
0
Altmetric
Research Article

MN/CA9: a potential gene marker for detection of malignant cells in effusions

, , , , , , , & show all
Pages 214-220 | Received 07 Aug 2006, Published online: 08 Oct 2008

References

  • Bedrossian, CWM. 1998. Diagnostic problems in serous effusions. Diagnostic Cytopathology, 19:131–137.
  • Buhr J, Berghauser KH, Gonner S, Kelm C, Burkhardt E, Padberg WM. The prognostic significance of tumor cell detection in intraoperative pleural lavage and lung tissue culture with lung cancer. Journal of Thorac Cardiovascular Surgery 1997; 113: 683–690
  • Chia SK, Wykoff CC, Watson PH, Han C, Leek RD, Pastorek J, Gatter KC, Ratcliffe P, Harris AL. Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma. Journal of Clinical Oncology 2001; 19: 3660–3668
  • Fetsch PA, Abati A. Immunocytochemistry in effusion cytology: a contemporary review. Cancer 2001; 93: 293–308
  • Fiegl M, Haun M, Massoner A, Krugmann J, Muller-Holzner E, Hack R, et al. Combination of cytology, fluorescence in situ hybridization for aneuploidy, and reverse-transcriptase polymerase chain reaction for human mammaglobin/mammaglobin B expression improves diagnosis of malignant effusions. Journal of Clinical Oncology 2004; 22: 474–483
  • Gerhard M, Juhl H, Kalthoff H, Schreiber HW, Wagener C, et al. Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction. Journal of Clinical Oncology 1994; 12: 725–729
  • Hedley D, Pintilie M, Woo J, Morrison A, Birle D, Fyles A, et al. Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas. Clinical Cancer Research 2003; 9: 5666–5674
  • Ivanov S, Liao SY, Ivanova A, Danilkovitch-Miagkova A, Tarasova N, Weirich G, et al. Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer. American Journal of Pathology 2001; 158: 905–919
  • Kim SJ, Rabbani ZN, Vollmer RT, Schreiber EG, Oosterwijk E, Dewhirst MW, et al. Carbonic anhydrase IX in early-stage non-small cell lung cancer. Clinical Cancer Research 2004; 10: 7925–7933
  • Kivela AJ, Parkkila S, Saarnio J, Karttunen TJ, Kivela J, Parkila AK, et al. Expression of von Hippel–Lindau tumor suppressor and tumor-associated carbonic anhydrases IX and XII in normal and neoplastic colorectal mucosa. World Journal of Gastroenterology 2005; 11: 2616–2625
  • Kowalewska M, Radziszewski J, Kulik J, Barathova M, Nasierowska-Guttmajer A, Bidzinski M, et al. Detection of carbonic anhydrase 9-expressing tumor cells in the lymph nodes of vulvar carcinoma patients by RT-PCR. International Journal of Cancer 2005; 116: 957–962
  • Lee WY. Limitations of detection of malignancy in pleural effusions using ELISA-based TRAP assay: comparison with cytological examination. Cytopathology 2005; 16: 227–232
  • Li G, Cuilleron M, Cottier M, Gentil-Perret A, Lambert C, Genin C, et al. The use of MN/CA9 gene expression in identifying malignant solid renal tumors. European Urology 2006; 49: 401–405
  • Li G, Passebosc-Faure K, Lambert C, Gentil-Perret A, Blanc F, Oosterwijk E, et al. The expression of G250/MN/CA9 antigen by flow cytometry: its possible implication for detection of micrometastatic renal cancer cells. Clinical Cancer Research 2001; 7: 89–92
  • Liao SY, Aurelio ON, Jan K, Zavada J, Stanbridge EJ. Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney. Cancer Research 1997; 57: 2827–2833
  • Light RW. Tumor markers in undiagnosed pleural effusions. Chest 2004; 126: 1721–1722
  • Lloyd JM, Mclver CM, Stephenson SA, Hewett PJ, Rieger N, Hardingham JE. Identification of early-stage colorectal cancer patients at risk of relapse post-resection by immunobead reverse transcription-PCR analysis of peritoneal lavage fluid for malignant cells. Clinical Cancer Research 2006; 12: 417–423
  • McKiernan JM, Buttyan R, de la Taille A, Stifelman MD, Emanuel ER, Bagiella E, et al. The detection of renal carcinoma cells in the peripheral blood with an enhanced reverse transcriptase polymerase chain reaction assay for MN/CA9. Cancer 1999; 86: 492–497
  • Mohanty SK, Dey P. Serous effusions: diagnosis of malignancy beyond cytomorphology. An analytic review. Postgraduate Medical Journal 2003; 79: 569–574
  • Monte SA, Ehya H, Lang WR. Positive effusion cytology as the initial presentation of malignancy. Acta Cytologica 1987; 31: 448–452
  • Mori M, Mimori K, Ueo H, Tsuj K, Shiraishi T, Barnard GF, et al. Clinical significance of molecular detection of carcinoma cells in lymph nodes and peripheral blood by reverse transcription-polymerase chain reaction in patients with gastrointestinal or breast carcinomas. Journal of Clinical Oncology 1998; 16: 128–132
  • Nagel H, Werner C, Hemmerlein B. Real-time reverse transcription-polymerase chain reaction assay for GA733-2 m RNA in the detection of metastatic carcinoma cells in serous effusions. American Journal of Clinical Pathology 2003; 120: 888–901
  • Okamoto I, Morisaki T, Sasaki J, Miyake H, Matsumoto M, Suga M, et al. Molecular detection of cancer cells by competitive reverse transcription-polymerase chain reaction analysis of specific CD44 variant RNAs. Journal of the National Cancer Institute 1998; 90: 307–315
  • Passebosc-Faure K, Li G, Lambert C, Cottier M, Gentil-Perret A, Fournel P, et al. Evaluation of a panel of molecular markers for the diagnosis of malignant serous effusions. Clinical Cancer Research 2005; 11: 6862–6867
  • Porcel JM, Vives M, Esquerdas A, Salud A, Perez B, Rodriguez-Panadero F. Use of a panel of tumor markers (carcinoembryonic antigen, cancer antigen 125, carbohydrate antigen 15-3, and cytokeratin 19 fragments) in pleural fluid for the differential diagnosis of malignant and benign effusions). Chest 2004; 126: 1757–1763
  • Potter CP, Harris AJ. Diagnostic, prognostic and therapeutic implications of carbonic anhydrases in cancer. British Journal of Cancer 2003; 89: 2–7
  • Shitrit D, Zingerman B, Bar-Gil Shitrit A, Shlomi D, Kramer MR. Diagnostic value of CYFRA 21-1, CEA, CA19-9, CA 15-3, and CA 125 assays in pleural effusions: analysis of 116 cases and review of the literature. The Oncologists 2005; 10: 501–507
  • To EM, Chan WY, Chow C, Ng EK, Chung SC. Gastric cancer cell detection in peritoneal washing: cytology versus RT-PCR for CEA transcripts. Diagnostic Molecular Pathology 2003; 12: 88–95
  • Yang CT, Lee MH, Lan RS, Chen JK. Telomerase activity in pleural effusions: diagnostic significance. Journal of Clinical Oncology 1998; 16: 567–573
  • Yu CJ, Shew JY, Liaw YS, Kuo SH, Luh KT, et al. Application of mucin quantitative competitive reverse transcription polymerase chain reaction in assisting the diagnosis of malignant pleural effusion. American Journal of Respiratory and Critical Care Medicine 2001; 164: 1312–1318

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.