230
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Metabonomic characterization of early atherosclerosis in hamsters with induced cholesterol

, , , , , , , , , , & show all
Pages 372-380 | Received 11 Nov 2008, Accepted 07 May 2009, Published online: 25 Jun 2009

References

  • A JY, Trygg J, Gullberg J, Johansson A, Jonsson P, Antti H, Marklund S, Moritz T. (2005). Extraction and GC/MS analysis of the human blood plasma metabolome. Anal Chem 77:8086–94.
  • Allain CC, Poon LS, Chen CS, Richmond W, Fu PC. (1974). Enzymatic determination of total serum cholesterol. Clin Chem 20:470–5.
  • Antoku Y, Tsukamoto K, Miyoshi Y, Nagino H, Anezaki M, Suwa K, Narabe Y. (2000). Correlations of elevated levels of hexacosanoate in erythrocyte membranes with risk factors for atherosclerosis. Atherosclerosis 153:169–73.
  • Bijnens AP, Lutgens E, Ayoubi T, Kuiper J, Horrevoets AJ, Daemen MJAP. (2006). Genome-wide expression studies of atherosclerosis: critical issues in methodology, analysis, interpretation of transcriptomics data. Arterioscler Thromb Vasc Biol 26:1226–35.
  • Brindle JT, Antti H, Holmes E, Tranter G, Nicholson JK, Bethell HWL, Clarke S, Schofield, PM, Mckilligin E, Mosedale DE, Grainger DJ. (2002). Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics. Nat Med 8:1439–44.
  • Bucolo G, David H. (1973). Quantitative determination of serum triglycerides by the use of enzymes. Clin Chem 36:476–82.
  • Daumerie CE, Woollett LA, Dietschy JM. (1992). Fatty acids regulate hepatic low density lipoprotein receptor activity through redistribution of intracellular cholesterol pools. Proc Natl Acad Sci USA 89:10797–801.
  • Dumas ME, Barton RH, Toye A, Cloarec O, Blancher C, Rothwell A, Fearnside J, Tatoud R, Blanc V, Lindon J, Mitchell SC, Holmes E, McCarthy MI, Scott J, Gauguier D, Nicholson JK. (2006). Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice. Proc Natl Acad Sci USA 103:1511–16.
  • Eriksson L, Johansson E, Kettaneh-Wold N, Wold S. (2001). Multi- and megavariate data analysis principles and applications. Umea, Sweden: Umetrics Academy, Umetrics AB.
  • Hui DY. (2003). HIV protease inhibitors and atherosclerosis. J Clin Invest 111:317–18.
  • Jonsson P, Johansson AI, Gullberg J, Trygg J, A JY, Grung B, Marklund S, Sjöström M, Antti H, Moritz T. (2005). High-throughput data analysis for detecting and identifying differences between samples in GC/MS-Based metabolomic analyses. Anal Chem 77:5635–42.
  • Kenny LC, Dunn WB, Ellis DI, Myers J, Baker PN, Kell DB. (2005). Novel biomarkers for pre-eclampsia detected using metabolomics and machine learning. Metabolomics 1:227–34.
  • Kleemann R, Verschuren L, Erk MJ, Nikolsky Y, Cnubben NHP, Verheij ER, Smilde AK, Hendriks HFJ, Zadelaar S, Smith GJ, Kaznacheev V, Nikolskaya T, Melnikov A, Hurt-Camejo E, Greef J, Ommen B, Kooistra T. (2007). Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis. Genome Biol 8:R200.
  • Kris-Etherton PM, Dietschy J. (1997). Design criteria for studies examining individual fatty acid effects on cardiovascular disease risk factors: human and animal studies. Am J Clin Nutr 65 (Suppl.):1590S–6S.
  • Lahoz C, Mostaza, JM. (2007). Atherosclerosis as a systemic disease. Rev Esp Cardiol 60:184–95.
  • Lescano-De-Souza AJ, Curi R. (1999). Cholesterol inhibits glutamine metabolism in LLC WRC256 tumour cells but does not affect it in lymphocytes: possible implications for tumour cell proliferation. Cell Biochem Funct 17:223–38.
  • Lusis AJ. (2000). Atherosclerosis. Nature 407:233–41.
  • Mayr M, Chung Y, Mayr U, Yin X, Ly L, Troy H, Fredericks S, Hu Y, Griffiths JR, Xu Q. (2005). Proteomic and metabolomic analyses of atherosclerotic vessels from apolipoprotein E-deficient mice reveal alterations in inflammation, oxidative stress, and energy metabolism. Arterioscler Thromb Vasc Biol 25:2135–42.
  • Nicholson J, Lindon, J, Holmes E. (1999). ‘Metabonomics’: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis for biological NMR spectroscopic data. Xenobiotica 29:1181–9.
  • Nistor A, Bulla A, Filip DA, Radu A. (1987). The hyperlipidemic hamster as a model of experimental atherosclerosis. Atherosclerosis 68:159–73.
  • Sabatine MS, Liu E, Morrow DA, Heller E, McCarroll R, Wiegand R, Berriz GF, Roth FP, Gerszten RE. (2005). Metabolomic identification of novel biomarkers of myocardial ischemia. Circulation 112:3868–75.
  • Sato T, Saito T, Yoshinaga K. (1985). The chemical composition of the thoracic aorta in diabetic and non-diabetic rats. Tohoku J Exp Med 147:357–64.
  • Steinberg D. (2002). Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime. Nat Med 8:1211–17.
  • Sung HJ, Ryang YS, Jang SW, Lee CW, Han KH, Ko J. (2006). Proteomic analysis of differential protein expression in atherosclerosis. Biomarkers 11:279–90.
  • Trygg J, Lundstedt T. (2007). Chemometrics techniques for metabonomics. J Proteome Res 6:469–79.
  • Tuomisto TT, Binder BR, Ylä-Herttuala S. (2005). Genetics, genomics and proteomics in atherosclerosis research. Ann Med 37:323–32.
  • Weingand KW, Daggy BP. (1990). Quantitation of high-density lipoprotein cholesterol in plasma from hamsters by differential precipitation. Clin Chem 36:575.
  • Wold S. (1978). Cross-validatory estimation of the number of components in factor and principal components models. Technometrics 20:397–405.
  • Woollett LA, Spady DK, Dietschy JM. (1992). Regulatory effects of the saturated fatty acids 6:0 through 18:0 on hepatic low density lipoprotein receptor activity in the hamster. J Clin Invest 89:1133–41.
  • Yi LZ, Yuan DL, Che ZH, Liang YZ, Zhou ZG, Gao HY, Wang YM. (2008). Plasma fatty acid metabolic profile coupled with uncorrelated linear discriminant analysis to diagnose and biomarker screening of type 2 diabetes and type 2 diabetic coronary heart diseases. Metabolomics 4:30–8.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.