N-acetylcysteine decreases urinary level of neutrophil gelatinase-associated lipocalin in deceased-donor renal transplant recipients: a randomized clinical trial

References

• Ampatzidou, F., et al., 2012. Neutrophil gelatinase-associated lipocalin as emerging biomarker of acute renal failure in renal transplant patient after coronary artery bypass surgery. Journal of cardiovascular surgery (Torino), 53, 805–808.
   PubMed Web of Science ®Google Scholar
• Barrera-Chimal, J. and Bobadilla, N.A., 2012. Are recently reported biomarkers helpful for early and accurate diagnosis of acute kidney injury? Biomarkers, 17, 385–393.
   PubMed Web of Science ®Google Scholar
• Boom, H., et al., 2000. Delayed graft function influences renal function, but not survival. Kidney international, 58, 859–866.
   PubMed Web of Science ®Google Scholar
• Buemi, A., et al., 2014. Is plasma and urine neutrophil gelatinase-associated lipocalin (NGAL) determination in donors and recipients predictive of renal function after kidney transplantation? Clinical biochemistry, 47, 68–72.
   PubMed Web of Science ®Google Scholar
• Choi, H.M., et al., 2013. Urine neutrophil gelatinase-associated lipocalin predicts graft outcome up to 1 year after kidney transplantation. Transplantation proceedings, 45, 122–128.
   PubMed Web of Science ®Google Scholar
• Daly, P.J., et al., 2005. Delayed graft function: a dilemma in renal transplantation. BJU international, 96, 498–501.
   PubMed Web of Science ®Google Scholar
• Danilovic, A., et al., 2011. Protective effect of N-acetylcysteine on early outcomes of deceased renal transplantation. Transplantation proceedings, 43, 1443–1449.
   PubMed Web of Science ®Google Scholar
• Devarajan, P., 2008. Neutrophil gelatinase-associated lipocalin–an emerging troponin for kidney injury. Nephrology dialysis transplantation, 23, 3737–3743.
   PubMed Web of Science ®Google Scholar
• Eremenko, A.A., et al., 2014. [Neutrophil gelatinase-associated lipocalin (u-NGAL) in the assessment of renal function in patients after kidney allotransplantation]. Anesteziologiia reanimatologiia, 59, 10–15.
   PubMedGoogle Scholar
• Field, M., et al., 2014. The use of NGAL and IP-10 in the prediction of early acute rejection in highly sensitized patients following HLA-incompatible renal transplantation. Transplant international, 27, 362–370.
   PubMed Web of Science ®Google Scholar
• Fishbane, S., 2008. N-acetylcysteine in the prevention of contrast-induced nephropathy. Clinincal journal of the American society of nephrology, 3, 281–287.
   PubMed Web of Science ®Google Scholar
• Fonseca, I., et al., 2014. Oxidative stress in kidney transplantation: malondialdehyde is an early predictive marker of graft dysfunction. Transplantation, 97, 1058–1065.
   PubMed Web of Science ®Google Scholar
• Fuller, T.F., et al., 2004. Influence of donor pretreatment with N-acetylcysteine on ischemia/reperfusion injury in rat kidney grafts. Journal of urology, 171, 1296–1300.
   PubMed Web of Science ®Google Scholar
• Haase, M., et al., 2009. Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis. American journal of kidney diseases, 54, 1012–1024.
   PubMed Web of Science ®Google Scholar
• Hall, I.E., et al., 2010. IL-18 and urinary NGAL predict dialysis and graft recovery after kidney transplantation. Journal of the American society of nephrology, 21, 189–197.
   PubMed Web of Science ®Google Scholar
• Han, M., et al., 2012. Renal neutrophil gelatinase associated lipocalin expression in lipopolysaccharide-induced acute kidney injury in the rat. BMC nephrology, 13, 25.
   PubMed Web of Science ®Google Scholar
• Hollmen, M.E., et al., 2014. Serum neutrophil gelatinase-associated lipocalin and recovery of kidney graft function after transplantation. BMC nephrology, 15, 123.
   PubMed Web of Science ®Google Scholar
• Kanter, J., et al., 2013. Urinary neutrophil gelatinase-associated lipocalin after kidney transplantation: is it a good biomarker to assess delayed graft function? Transplantation proceedings, 45, 1368–1370.
   PubMed Web of Science ®Google Scholar
• Kohei, J., et al., 2013. Neutrophil gelatinase-associated lipocalin is a sensitive biomarker for the early diagnosis of acute rejection after living-donor kidney transplantation. International urology and nephrology, 45, 1159–1167.
   PubMed Web of Science ®Google Scholar
• Kumar, A., et al., 2016. Induction of IL-8(CXCL8) and MCP-1(CCL2) with oxidative stress and its inhibition with N-acetyl cysteine (NAC) in cell culture model using HK-2 cell. Transplant immunology, 35, 40–46.
   PubMed Web of Science ®Google Scholar
• Lacquaniti, A., et al., 2016. Delayed graft function and chronic allograft nephropathy: diagnostic and prognostic role of neutrophil gelatinase-associated lipocalin. Biomarkers, 21, 371–378.
   PubMed Web of Science ®Google Scholar
• Lippi, G., et al., 2012. Evaluation of NGAL Test, a fully-automated neutrophil gelatinase-associated lipocalin (NGAL) immunoassay on Beckman Coulter AU 5822. Clinical chemistry and laboratory medicine, 50, 1581–1584.
   Web of Science ®Google Scholar
• Magnusson, N.E., et al., 2012. Plasma neutrophil gelatinase associated lipocalin (NGAL) is associated with kidney function in uraemic patients before and after kidney transplantation. BMC nephrology, 13, 8.
   PubMed Web of Science ®Google Scholar
• Nafar, M., et al., 2011. Oxidative stress in kidney transplantation: causes, consequences, and potential treatment. Iranian journal of kidney diseases, 5, 357–372.
   PubMed Web of Science ®Google Scholar
• Nishida, M., et al., 2010. Serum and urinary neutrophil gelatinase-associated lipocalin levels in children with chronic renal diseases. Pediatrics international, 52, 563–568.
   PubMed Web of Science ®Google Scholar
• Nitescu, N., et al., 2006. N-acetylcysteine attenuates kidney injury in rats subjected to renal ischaemia-reperfusion. Nephrology dialysis transplantation, 21, 1240–1247.
   PubMed Web of Science ®Google Scholar
• Pajek, J., et al., 2014. Non-inferiority of creatinine excretion rate to urinary L-FABP and NGAL as predictors of early renal allograft function. BMC nephrology, 15, 117.
   PubMed Web of Science ®Google Scholar
• Parikh, C.R., et al., 2006. Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation. American journal of transplantation, 6, 1639–1645.
   PubMed Web of Science ®Google Scholar
• Qurashi, S., et al., 2014. Urinary neutrophil gelatinase-associated lipocalin and the occurrence of delayed graft function after kidney transplant. Experimental and clinical transplantation, 12, 396–400.
   PubMed Web of Science ®Google Scholar
• Ramirez-Sandoval, J.C., et al., 2014. Urinary neutrophil gelatinase-associated lipocalin predicts graft loss after acute kidney injury in kidney transplant. Biomarkers, 19, 63–69.
   PubMed Web of Science ®Google Scholar
• Ruiz Fuentes, M.C., et al., 2008. Treatment with N-acetylcysteine in stable renal transplantation. Transplantation proceedings, 40 (9), 2897.
   PubMed Web of Science ®Google Scholar
• Sahraei, Z., Salamzadeh, J., and Nafar, M., 2015. Effect of N-acetyl cysteine and vitamin C on kidney allograft function biomarkers interleukin-18 and neutrophil gelatinase-associated lipocalin. Iranian journal of kidney diseases, 9, 56–62.
   PubMed Web of Science ®Google Scholar
• Sehirli, A.O., et al., 2003. Protective effect of N-acetylcysteine on renal ischemia/reperfusion injury in the rat. Journal of nephrology, 16, 75–80.
   PubMed Web of Science ®Google Scholar
• Shimizu, M.H., et al., 2008. N-acetylcysteine protects against renal injury following bilateral ureteral obstruction. Nephrology dialysis transplantation, 23, 3067–3073.
   PubMed Web of Science ®Google Scholar
• Siedlecki, A., Irish, W., and Brennan, D.C., 2011. Delayed graft function in the kidney transplant. American journal of transplantation: official journal of the American society of transplantation and the American society of transplant surgeons, 11, 2279–2296.
   PubMed Web of Science ®Google Scholar
• Urbschat, A., Obermuller, N., and Haferkamp, A., 2011. Biomarkers of kidney injury. Biomarkers, 16 (Suppl 1), S22–S30.
   PubMed Web of Science ®Google Scholar
• Yarlagadda, S.G., et al., 2009. Association between delayed graft function and allograft and patient survival: a systematic review and meta-analysis. Nephrology dialysis transplantation, 24, 1039–1047.
   PubMed Web of Science ®Google Scholar
• Zeger, S.L. and Liang, K.Y., 1986. Longitudinal data analysis for discrete and continuous outcomes. Biometrics, 42, 121–130.
   PubMed Web of Science ®Google Scholar