Cardiac extracellular matrix modulation in a rat-diabetic model: biochemical and anti-oxidant beneficial effect of pomegranate (Punica granatum) peel extract

References

• Abdel-Wahhab, K.G., et al., 2018. Efficiencies of low-level laser therapy (LLLT) and gabapentin in the management of peripheral neuropathy: diabetic neuropathy. Applied biochemistry and biotechnology, 186 (1), 161–173.
   PubMed Web of Science ®Google Scholar
• Ahmad, M., et al., 2008. Antidiabetic and hypolipidemic effects of aqueous methanolic extract of Acacia nilotica pods in alloxan-induced diabetic rabbits. Scandinavian journal of laboratory animal sciences, 35 (1), 29–34.
   Web of Science ®Google Scholar
• Almeida, M.E.S., et al., 2016. Hyperglycemia reduces integrin subunits alpha v and alpha 5 on the surface of dermal fibroblasts contributing to deficient migration. Molecular and cellular biochemistry, 421 (1–2), 19–28.
   PubMed Web of Science ®Google Scholar
• Aslam, M.N., Lansky, E.P., and Varani, J., 2006. Pomegranate as a cosmeceutical source: pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. Journal of ethnopharmacology, 103 (3), 311–318.
   PubMed Web of Science ®Google Scholar
• Assiri, A.M., et al., 2017. Ameliorative impact of Morus alba leaves’ aqueous extract against embryonic ophthalmic tissue malformation in streptozotocin-induced diabetic rats. Biomedicine and pharmacotherapy, 95, 1072–1081.
   PubMed Web of Science ®Google Scholar
• Baradaran, R.V., et al., 2020. Antiinflammatory and anti‐cancer activities of pomegranate and its constituent, ellagic acid: evidence from cellular, animal, and clinical studies. Phytotherapy research, 34 (4), 685–720.
   PubMed Web of Science ®Google Scholar
• Bell, D.S., 2003. Heart failure: the frequent, forgotten, and often fatal complication of diabetes. Diabetes care, 26 (8), 2433–2441.
   PubMed Web of Science ®Google Scholar
• Benlarbi, F., Stoker, P., and Yousfi, M., 2018. Investigation of antioxidant and antihemolytic activities of Algerian defatted olive fruits (Olea europaea L.) at two ripening stages. Mediterranean journal of nutrition and metabolism, 11 (3), 217–233.
   Web of Science ®Google Scholar
• Brassard, P., Amiri, F., and Schiffrin, E.L., 2005. Combined angiotensin II type 1 and type 2 receptor blockade on vascular remodeling and matrix metalloproteinases in resistance arteries. Hypertension, 46 (3), 598–606.
   PubMed Web of Science ®Google Scholar
• Chidambara Murthy, K.N., et al., 2004. Study on wound healing activity of Punica granatum peel. Journal of medicinal food, 7 (2), 256–259.
   PubMed Web of Science ®Google Scholar
• Chikhi, I., et al., 2014. Antidiabetic activity of aqueous leaf extract of Atriplex halimus L.(Chenopodiaceae) in streptozotocin–induced diabetic rats. Asian pacific journal of tropical disease, 4 (3), 181–184.
   Google Scholar
• Chu, K. A., et al., 2019. Reversal of bleomycin-induced rat pulmonary fibrosis by a xenograft of human umbilical mesenchymal stem cells from Wharton's jelly. Theranostics, 9 (22), 6646.
   Google Scholar
• Dab, H., et al., 2009. Differential control of MMP and t-PA/PAI-1 expressions by sympathetic and renin–angiotensin systems in rat left ventricle. Autonomic neuroscience: basic & clinical, 150 (1–2), 27–32.
   PubMed Web of Science ®Google Scholar
• Debessa, C.R.G., Maifrino, L.B.M., and de Souza, R.R., 2001. Age related changes of the collagen network of the human heart. Mechanisms of ageing and development, 122 (10), 1049–1058.
   PubMed Web of Science ®Google Scholar
• Eddouks, M., Lemhadri, A., and Michel, J.B., 2005. Hypolipidemic activity of aqueous extract of Capparis spinosa L. in normal and diabetic rats. Journal of ethnopharmacology, 98 (3), 345–350.
   PubMed Web of Science ®Google Scholar
• Elfalleh, W., et al., 2012. Total phenolic contents and antioxidant activities of pomegranate peel, seed, leaf and flower. Journal of medicinal plants research, 6 (32), 4724–4730.
   Google Scholar
• Elfalleh, W., et al., 2009. Physico-chemical properties and DPPH-ABTS scavenging activity of some local pomegranate (Punica granatum) ecotypes. International journal of food sciences and nutrition, 60 (2), 197–210.
   PubMed Web of Science ®Google Scholar
• Elfalleh, W., et al., 2011. Antioxidant capacities of phenolic compounds and tocopherols from Tunisian pomegranate (Punica granatum) fruits. Journal of food science, 76 (5), C707–C713.
   PubMed Web of Science ®Google Scholar
• El‐Hadary, A.E. and Ramadan, M.F., 2019. Phenolic profiles, antihyperglycemic, antihyperlipidemic, and antioxidant properties of pomegranate (Punica granatum) peel extract. Journal of food biochemistry, 43 (4), e12803.
   PubMed Web of Science ®Google Scholar
• Frangogiannis, N.G., 2019. The extracellular matrix in ischemic and nonischemic heart failure. Circulation research, 125 (1), 117–146.
   PubMed Web of Science ®Google Scholar
• Fratianni, F., et al., 2007. Polyphenolic composition in different parts of some cultivars of globe artichoke (Cynara cardunculus L. var. scolymus (L.) Fiori). Food chemistry, 104 (3), 1282–1286.
   Web of Science ®Google Scholar
• Ghedadba, N., et al., 2015. Polyphénols totaux, activités antioxydante et antimicrobienne des extraits des feuilles de Marrubium deserti de Noé. Phytothérapie, 13 (2), 118–129.
   Google Scholar
• Glovaci, D., Fan, W., and Wong, N.D., 2019. Epidemiology of diabetes mellitus and cardiovascular disease. Current cardiology reports, 21 (4), 1–8.
   PubMed Web of Science ®Google Scholar
• Hamed, S., et al., 2010. Topical erythropoietin promotes wound repair in diabetic rats. The journal of investigative dermatology, 130 (1), 287–294.
   PubMed Web of Science ®Google Scholar
• Horn, M.A., et al., 2012. Age-related divergent remodeling of the cardiac extracellular matrix in heart failure: collagen accumulation in the young and loss in the aged. Journal of molecular and cellular cardiology, 53 (1), 82–90.
   PubMed Web of Science ®Google Scholar
• Hsu, C., et al., 1986. The influence of estrogen on the hyperglycemic action of alloxan in female rats. Proceedings of the National Science Council, Republic of China. Part B, life sciences, 10 (2), 92.
   PubMedGoogle Scholar
• Humphrey, J.D., 2008. Vascular adaptation and mechanical homeostasis at tissue, cellular, and sub-cellular levels. Cell biochemistry and biophysics, 50 (2), 53–78.
   PubMed Web of Science ®Google Scholar
• Iozzo, P., et al., 2002. Independent association of type 2 diabetes and coronary artery disease with myocardial insulin resistance. Diabetes, 51 (10), 3020–3024.
   PubMed Web of Science ®Google Scholar
• Ismail, T., Sestili, P., and Akhtar, S., 2012. Pomegranate peel and fruit extracts: a review of potential anti-inflammatory and anti-infective effects. Journal of ethnopharmacology, 143 (2), 397–405.
   PubMed Web of Science ®Google Scholar
• Johnsen, S.P., et al., 2003. Intake of fruit and vegetables and the risk of ischemic stroke in a cohort of Danish men and women. The american journal of clinical nutrition, 78 (1), 57–64.
   PubMed Web of Science ®Google Scholar
• Langhi, C. and Cariou, B., 2010. Cholesterol metabolism and beta-cell function. Médecine/sciences, 26 (4), 385–390.
   Google Scholar
• Lenzen, S., 2008. The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia, 51 (2), 216–220.
   PubMed Web of Science ®Google Scholar
• Li, W., et al., 2017. Increased vascular and uteroplacental matrix metalloproteinase-1 and-7 levels and collagen type I deposition in hypertension in pregnancy: role of TNF-α. American journal of physiology. Heart and circulatory physiology, 313 (3), H491–H507.
   PubMed Web of Science ®Google Scholar
• Lindau-Shepard, B.A. and Shaffer, J.B., 1993. Expression of human catalase in acatalasemic murine SV-B2 cells confers protection from oxidative damage. Free radical biology & medicine, 15 (6), 581–588.
   PubMed Web of Science ®Google Scholar
• Maione, A.G., et al., 2016. Altered ECM deposition by diabetic foot ulcer‐derived fibroblasts implicates fibronectin in chronic wound repair. Wound repair and regeneration, 24 (4), 630–643.
   PubMed Web of Science ®Google Scholar
• Malemud, C.J., 2006. Matrix metalloproteinases (MMPs) in health and disease: an overview. Frontiers in bioscience, 11 (1), 1696–1701.
   PubMedGoogle Scholar
• Mekawi, E.M., Sharoba, A.M., and Ramadan, M.F., 2019. Reduction of acrylamide formation in potato chips during deep-frying in sunflower oil using pomegranate peel nanoparticles extract. Journal of food measurement and characterization, 13 (4), 3298–3306.
   Web of Science ®Google Scholar
• Meschiari, C.A., et al., 2017. The impact of aging on cardiac extracellular matrix. GeroScience, 39 (1), 7–18.
   PubMed Web of Science ®Google Scholar
• Mis, L., et al., 2018. Effect of wheatgrass on DNA damage, oxidative stress index and histological findings in diabetic rats. International journal of morphology, 36 (4), 1235–1240.
   Web of Science ®Google Scholar
• Mohammad, S.M. and Kashani, H.H., 2012. Chemical composition of the plant Punica granatum L. (Pomegranate) and its effect on heart and cancer. Journal of medicinal plants research, 6 (40), 5306–5310.
   Google Scholar
• Nagano, M., Fukami, K., Yamagishi, S. I., Ueda, S., Kaida, Y., Matsumoto, T., and Okuda, S., 2009. Circulating matrix metalloproteinase-2 is an independent correlate of proteinuria in patients with chronic kidney disease. American journal of nephrology, 29 (2), 109–115.
   Google Scholar
• Negreş, S., et al., 2013. Experimental pharmacological model of diabetes induction with alloxan in rat. Farmacia, 61 (2), 313–323.
   Web of Science ®Google Scholar
• Pagliarulo, C., et al., 2016. Inhibitory effect of pomegranate (Punica granatum L.) polyphenol extracts on the bacterial growth and survival of clinical isolates of pathogenic Staphylococcus aureus and Escherichia coli. Food chemistry, 190, 824–831.
   PubMed Web of Science ®Google Scholar
• Palacios, I., et al., 2011. Antioxidant properties of phenolic compounds occurring in edible mushrooms. Food chemistry, 128 (3), 674–678.
   Web of Science ®Google Scholar
• Pande, G. and Akoh, C.C., 2009. Antioxidant capacity and lipid characterization of six Georgia-grown pomegranate cultivars. Journal of agricultural and food chemistry, 57 (20), 9427–9436.
   PubMed Web of Science ®Google Scholar
• Parmar, H.S. and Kar, A., 2007. Antidiabetic potential of Citrus sinensis and Punica granatum peel extracts in alloxan treated male mice. BioFactors, 31 (1), 17–24.
   PubMed Web of Science ®Google Scholar
• Polle, A., Krings, B., and Rennenberg, H., 1989. Superoxide dismutase activity in needles of Norwegian spruce trees (Picea abies L.). Plant physiology, 90 (4), 1310–1315.
   PubMed Web of Science ®Google Scholar
• Rahman, M.A., et al., 2020. The expression of transforming growth factor-β1 and type I collagen on the right ventricle of rat models with pulmonary arterial hypertension administered with pomegranate extract. EurAsian journal of BioSciences, 14 (2), 3719–3723.
   Google Scholar
• Ravi, K., Rajasekaran, S., and Subramanian, S., 2005. Antihyperlipidemic effect of Eugenia jambolana seed kernel on streptozotocin-induced diabetes in rats. Food and chemical toxicology, 43 (9), 1433–1439.
   PubMed Web of Science ®Google Scholar
• Ribeiro, C., et al., 2012. Effects of physical training with different intensities of effort on lipid metabolism in rats submitted to the neonatal application of alloxan. Lipids in health and disease, 11 (1), 138.
   PubMedGoogle Scholar
• Rissanen, T.H., et al., 2003. Low intake of fruits, berries and vegetables is associated with excess mortality in men: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study. The journal of nutrition, 133 (1), 199–204.
   PubMed Web of Science ®Google Scholar
• Saad, A.B., et al., 2016. Malva sylvestris extract protects upon lithium carbonate-induced kidney damages in male rat. Biomedicine & pharmacotherapy, 84, 1099–1107.
   PubMed Web of Science ®Google Scholar
• Sadeghipour, A., et al., 2014. Lipid lowering effect of Punica granatum L. peel in high lipid diet fed male rats. Evidence-Based complementary and alternative medicine, 2014, 1–5.
   Web of Science ®Google Scholar
• Sanadhya, I., et al., 2013. Antidiabetic activity of Anthocephalus indicus a. rich. fruits in alloxan induced diabetic rats. International journal of pharmacy and pharmaceutical sciences, 5 (2), 519–523.
   Google Scholar
• Senthilkumar, R. and John, S., 2008. Hypoglycaemic activity of marine cyanobacteria in alloxan induced diabetic rats. Pharmacologyonline, 2, 704–714.
   Google Scholar
• Sonbol, H.S., 2018. Extracellular matrix remodeling in human disease. Journal of microscopy and ultrastructure, 6 (3), 123–128.
   PubMedGoogle Scholar
• Strain, W.D. and Paldánius, P.M., 2018. Diabetes, cardiovascular disease and the microcirculation. Cardiovascular diabetology, 17 (1), 1–10.
   PubMedGoogle Scholar
• Szkudelski, T., 2001. The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiological research, 50 (6), 537–546.
   PubMed Web of Science ®Google Scholar
• Temple, N.J. and Gladwin, K.K., 2003. Fruit, vegetables, and the prevention of cancer: research challenges. Nutrition, 19 (5), 467–470.
   PubMed Web of Science ®Google Scholar
• Thrailkill, K. M., et al., 2007. Matrix metalloproteinase-2 dysregulation in type 1 diabetes. Diabetes care, 30 (9), 2321–2326.
   Google Scholar
• Uwaezuoke, S.N., 2017. The role of novel biomarkers in predicting diabetic nephropathy: a review. International journal of nephrology and renovascular disease, 10, 221–231.
   PubMed Web of Science ®Google Scholar
• Volkova, M., et al., 2012. The role of Toll-like receptors in age-associated lung diseases. Journals of gerontology series A: biomedical sciences and medical sciences, 67 (3), 247–253.
   PubMed Web of Science ®Google Scholar
• Vučić, V., et al., 2019. Composition and potential health benefits of pomegranate: a review. Current pharmaceutical design, 25 (16), 1817–1827.
   PubMed Web of Science ®Google Scholar
• Westermann, D., et al., 2007. Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy: the role of angiotensin type 1 receptor antagonism. Diabetes, 56 (3), 641–646.
   Google Scholar
• Wei, X., et al., 2020. Pomegranate peel extract ameliorates liver fibrosis induced by carbon tetrachloride in rats through suppressing p38MAPK/Nrf2 pathway. Journal of functional foods, 65, 103712.
   Web of Science ®Google Scholar
• Xuan, Y.H., et al., 2014. High-glucose inhibits human fibroblast cell migration in wound healing via repression of bFGF-regulating JNK phosphorylation. PLoS One, 9 (9), e108182.
   PubMed Web of Science ®Google Scholar