331
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Prevalence of depression among Chinese medical students: A systematic review and meta-analysis

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 2212-2228 | Received 12 Apr 2021, Accepted 28 Jun 2021, Published online: 07 Jul 2021

References

  • Arrieta, J., Aguerrebere, M., Raviola, G., Flores, H., Elliott, P., Espinosa, A., Reyes, A., Ortiz-Panozo, E., Rodriguez-Gutierrez, E., Mukherjee, J., Palazuelos, D., & Franke, M. (2017). Validity and utility of the Patient Health Questionnaire (PHQ)-2 and PHQ-9 for screening and diagnosis of depression in rural Chiapas, Mexico: A cross-sectional study. Journal of Clinical Psychology, 73(9), 1076–1090. https://doi.org/10.1002/jclp.22390
  • Azad, M. C., Fraser, K., Rumana, N., Abdullah, A. F., Shahana, N., Hanly, P. J., & Turin, T. C. (2015). Sleep disturbances among medical students: A global perspective. Journal of Clinical Sleep Medicine, 11(1), 69–74. https://doi.org/10.5664/jcsm.4370
  • Baglioni, C., Battagliese, G., Feige, B., Spiegelhalder, K., Nissen, C., Voderholzer, U., Lombardo, C., & Riemann, D. (2011). Insomnia as a predictor of depression: A meta-analytic evaluation of longitudinal epidemiological studies. Journal of Affective Disorders, 135(1–3), 10–19. https://doi.org/10.1016/j.jad.2011.01.011
  • Bjelland, I., Dahl, A., Haug, T., & Neckelmann, D. (2002). The validity of the Hospital Anxiety and Depression Scale. An updated literature review. Journal of Psychosomatic Research, 52(2), 69–77. https://doi.org/10.1016/S0022-3999(01)00296-3
  • Cao, R., Gao, T., Hu, Y., Qin, Z., Ren, H., Liang, L., Li, C., & Mei, S. (2020). Clustering of lifestyle factors and the relationship with depressive symptoms among adolescents in Northeastern China. Journal of Affective Disorders, 274(2020), 704–710. https://doi.org/10.1016/j.jad.2020.05.064
  • Cunningham, J. E. A., Stamp, J. A., & Shapiro, C. M. (2019). Sleep and major depressive disorder: A review of non-pharmacological chronotherapeutic treatments for unipolar depression. Sleep Medicine, 61(2019), 6–18. https://doi.org/10.1016/j.sleep.2019.04.012
  • DE, F., & Db, K. (1989). Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention? JAMA, 262(11), 1479–1484. https://doi.org/10.1001/jama.262.11.1479
  • Domhardt, M., Steubl, L., Boettcher, J., Buntrock, C., Karyotaki, E., Ebert, D. D., Cuijpers, P., & Baumeister, H. (2020). Mediators and mechanisms of change in internet- and mobile-based interventions for depression: A systematic review. Clinical Psychology Review, 83(02), 101953. https://doi.org/10.1016/j.cpr.2020.101953
  • Egger, M., Smith, G. D., Schneider, M., & Minder, C. E. (1997). Bias in meta-analysis detected by a simple, graphical test. Bmj, 315(7109), 629–634. https://doi.org/10.1136/bmj.315.7109.629
  • Fawzy, M., & Hamed, S. A. (2017). Prevalence of psychological stress, depression and anxiety among medical students in Egypt. Psychiatry Research, 255(09), 186–194. https://doi.org/10.1016/j.psychres.2017.05.027
  • Feng, G. S., Chen, J. W., & Yang, X. Z. (2005). A survey of sleep quality of medical college students and analysis of its influencing factors. Chinese Journal of Epidemiology, 26(5), 328–331.
  • Furukawa, T. A., Efthimiou, O., Weitz, E. S., Cipriani, A., Keller, M. B., Kocsis, J. H., Klein, D. N., Michalak, J., Salanti, G., Cuijpers, P., & Schramm, E. (2018). Cognitive-behavioral analysis system of psychotherapy, drug, or their combination for persistent depressive disorder: Personalizing the treatment choice using individual participant data network metaregression. Psychotherapy and Psychosomatics, 87(3), 140–153. https://doi.org/10.1159/000489227
  • Guo, K., Liu, M. L., Chen, W., & Wang, Z. F. (2014). A study on depression and its influencing factors of medical students in Qinghai University. Chinese Journal of Disease Control & Prevention, 18(2), 475–476.
  • Hu, J., Dong, Y., Chen, X., Liu, Y., Ma, D., Liu, X., Zheng, R., Mao, X., Chen, T., & He, W. (2015). Prevalence of suicide attempts among Chinese adolescents: A meta-analysis of cross-sectional studies. Comprehensive Psychiatry, 61(2015), 78–89. https://doi.org/10.1016/j.comppsych.2015.05.001
  • Imajo, K., Kessoku, T., Honda, Y., Tomeno, W., Ogawa, Y., Mawatari, H., Fujita, K., Yoneda, M., Taguri, M., Hyogo, H., Sumida, Y., Ono, M., Eguchi, Y., Inoue, T., Yamanaka, T., Wada, K., Saito, S., & Nakajima, A. (2016). Magnetic resonance imaging more accurately classifies steatosis and fibrosis in patients with nonalcoholic fatty liver disease than transient elastography. Gastroenterology, 150(3), 626–637 e627. https://doi.org/10.1053/j.gastro.2015.11.048
  • Jiang, H. C., Mao, Y., & Li, Y. Q. (2016). Correlation analysis of sleep quality, anxiety and depression among medical students in frontier provinces. Chinese Journal of Public Health Management, 32(3), 305–308. https://doi.org/10.19568/j.cnki.23-1318.2016.03.006
  • Jokelainen, J., Timonen, M., Keinänen-Kiukaanniemi, S., Härkönen, P., Jurvelin, H., & Suija, K. (2019). Validation of the Zung self-rating depression scale (SDS) in older adults. Scandinavian Journal of Primary Health Care, 37(3), 353–357. https://doi.org/10.1080/02813432.2019.1639923
  • Lew, B., Huen, J., Yu, P., Yuan, L., Wang, D. F., Ping, F., Abu Talib, M., Lester, D., Jia, C. X., & Innamorati, M. (2019). Associations between depression, anxiety, stress, hopelessness, subjective well-being, coping styles and suicide in Chinese university students. PLoS One, 14(7), e0217372. https://doi.org/10.1371/journal.pone.0217372
  • Li, X., Yu, L., Gao, J., Pei, Y., Xu, F., & Kong, J. (2017). An epidemiological survey of depression in college students of traditional Chinese Medicine. China Medical Herald, 14(8), 49–52.
  • Li, X. X., Zhang, X. M., Wu, F. Y., Ma, J., Yue, M. J., Yun, Y. X., Jin, L., & Liu, H. J. (2018). Anxiety and depression of medical students in Changchun City and their relationship with type A behavior. Medicine and Society, 208(2), 55–58+62. https://doi.org/10.1016/j.socscimed.2018.05.008
  • Li, Y. C., Hu, C. L., Tao, X. Y., Ruan, L., & Jing, S. B. (2005). Study on the relationship between anxiety depression and personality characteristics of medical students. Chinese Journal of School Health, 26(2), 107–108.
  • Liao, Y., Knoesen, N. P., Deng, Y., Tang, J., Castle, D. J., Bookun, R., Hao, W., Chen, X., & Liu, T. (2010). Body dysmorphic disorder, social anxiety and depressive symptoms in Chinese medical students. Social Psychiatry and Psychiatric Epidemiology, 45(10), 963–971. https://doi.org/10.1007/s00127-009-0139-9
  • Ln, D., Mr, T., & Td, S. (2006). Systematic review of depression, anxiety, and other indicators of psychological distress among U.S. and Canadian medical students. Academic Medicine: Journal of the Association of American Medical Colleges, 81(4), 354–373. https://doi.org/10.1097/00001888-200604000-00009
  • Mou, Y. Y., Li, D. L., Guo, Z. Q., & Li, Y. W. (2015). Correlation between sleep quality and anxiety depression of medical undergraduates. Chinese Nursing Research, 29(14), 1695–1697.
  • Ng, K., Wu, L., Lam, H., Lam, L., Nip, P., Ng, C., Leung, K., & Leung, S. (2020). The relationships between mobile phone use and depressive symptoms, bodily pain, and daytime sleepiness in Hong Kong secondary school students. Addictive Behaviors, 101(02), 105975. https://doi.org/10.1016/j.addbeh.2019.04.033
  • Pan, X.-F., Wen, Y., Zhao, Y., Hu, J.-M., Li, S.-Q., Zhang, S.-K., Li, X.-Y., Chang, H., Xue, Q.-P., Zhao, Z.-M., Gu, Y., Li, -C.-C., Zhang, Y.-Q., Sun, X.-W., Yang, C.-X., & Fu, C. (2015). Prevalence of depressive symptoms and its correlates among medical students in China: A national survey in 33 universities. Psychology, Health & Medicine, 21(7), 882–889. https://doi.org/10.1080/13548506.2015.1127395
  • Rahmani, M., Rahmani, F., & Rezaei, N. (2020). The brain-derived neurotrophic factor: Missing link between sleep deprivation, insomnia, and depression. Neurochemical Research, 45(2), 221–231. https://doi.org/10.1007/s11064-019-02914-1
  • Shamseer, L., Moher, D., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., & Stewart, L. A. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: Elaboration and explanation. Bmj, 349(jan02 1), g7647–g7647. https://doi.org/10.1136/bmj.g7647
  • Shen, Y., Meng, F., Tan, S. N., Zhang, Y., Anderiescu, E. C., Abeysekera, R. E., Luo, X., & Zhang, X. Y. (2019). Excessive daytime sleepiness in medical students of Hunan province: Prevalence, correlates, and its relationship with suicidal behaviors. Journal of Affective Disorders, 255(2019), 90–95. https://doi.org/10.1016/j.jad.2019.05.036
  • Shen, Y., Zhang, Y., Chan, B. S. M., Meng, F., Yang, T., Luo, X., & Huang, C. (2020). Association of ADHD symptoms, depression and suicidal behaviors with anxiety in Chinese medical college students. BMC Psychiatry, 20(1), 180. https://doi.org/10.1186/s12888-020-02555-7
  • Shi, M., Liu, L., Wang, Z. Y., & Wang, L. (2016). Prevalence of depressive symptoms and its correlations with positive psychological variables among Chinese medical students: An exploratory cross-sectional study. BMC Psychiatry, 16(1), 1–8. https://doi.org/10.1186/s12888-016-0710-3
  • Smarr, K., & Keefer, A. (2011). Measures of depression and depressive symptoms: Beck Depression Inventory-II (BDI-II), Center for Epidemiologic Studies Depression Scale (CES-D), Geriatric Depression Scale (GDS), Hospital Anxiety and Depression Scale (HADS), and Patient Health Questionnaire-9 (PHQ-9). Arthritis Care & Research, 63(S11), S454–466. https://doi.org/10.1002/acr.20556
  • Sobowale, K., Zhou, A. N., Fan, J., Liu, N., & Sherer, R. (2014). Depression and suicidal ideation in medical students in China: A call for wellness curricula. International Journal of Medical Education, 5(5), 31–36. https://doi.org/10.5116/ijme.52e3.a465
  • Sun, L., Sun, L.-N., Sun, Y.-H., Yang, L.-S., Wu, H.-Y., Zhang, -D.-D., Cao, H.-Y., & Sun, Y. (2011). Correlations between psychological symptoms and social relationships among medical undergraduates in Anhui Province of China. The International Journal of Psychiatry in Medicine, 42(1), 29–47. https://doi.org/10.2190/PM.42.1.c
  • Szabó, M. (2010). The short version of the Depression Anxiety Stress Scales (DASS-21): Factor structure in a young adolescent sample. Journal of Adolescence, 33(1), 1–8. https://doi.org/10.1016/j.adolescence.2009.05.014
  • Upadhaya, S., Madala, S., Baniya, R., Saginala, K., & Khan, J. (2018). Impact of acetylsalicylic acid on primary prevention of cardiovascular diseases: A meta-analysis of randomized trials. European Journal of Preventive Cardiology, 26(7), 746–749. https://doi.org/10.1177/2047487318816387
  • Wang, M. L., Huang, X., Jing, J., Liu, J. A., & Li, X. H. (2004). A study on the relationship between personality characteristics and anxiety and depression of medical students. Chinese Journal of School Health, 25(6), 675–676.
  • Wang, Y., McNeil, E., Huang, Z., Chen, L., Lu, X., Wang, C., Chen, H., & Chongsuvivatwong, V. (2020). Household financial burden among multidrug-resistant tuberculosis patients in Guizhou province, China: A cross-sectional study. Medicine, 99(28), e21023. https://doi.org/10.1097/MD.0000000000021023
  • Wang, Y. P., & Gorenstein, C. (2013). Psychometric properties of the beck depression Inventory-II: A comprehensive review. Revista Brasileira De Psiquiatria, 35(4), 416–431. https://doi.org/10.1590/1516-4446-2012-1048
  • Wu, D., Rockett, I. R. H., Yang, T., Feng, X., Jiang, S., & Yu, L. (2016). Deliberate self-harm among Chinese medical students: A population-based study. Journal of Affective Disorders, 202(2016), 137–144. https://doi.org/10.1016/j.jad.2016.05.030
  • Wu, H., Tang, L. L., Deng, H. L., Zhao, Y., Yang, Y. L., Zhao, Y., Wang, T. F., & Wang, Q. G. (2012). Investigation and Analysis on the physical and mental health of college students in three colleges of traditional Chinese Medicine. Journal of Tianjin University of Traditional Chinese Medicine, 31(4), 237–241.
  • Xiao, H. B., Wang, F., Sun, S. G., Jiang, L. L., Yu, C. H., Zhang, S. J., & Zhang, L. (2008). Sleep status of medical students at different levels and its correlation with mental factors. Chinese Journal of School Health, 29(2), 146–148.
  • Yang, B. F., Liu, D. G., & Zhang, Q. M. (2000). Analysis of sleep quality and related factors of medical students. Chinese Journal of School Doctor, 14(6), 404–406.
  • Yang, L. J., Li, J., & Zhang, H. L. (2014). Study on the relationship between sleep quality and mental health of medical interns in Lhasa. China Higher Medical Education, 10(10), 50–51.
  • Yang, L. P., Yan, P. P., Li, X. M., Li, X. B., & Hou, J. L. (2012). Epidemiological investigation and analysis of depression of students in Henan College of traditional Chinese medicine before examination. Guangming Journal of Chinese Medicine, 27(12), 2398–2400.
  • Zeng, W., Chen, R., Wang, X., Zhang, Q., & Deng, W. (2019). Prevalence of mental health problems among medical students in China: A meta-analysis. Medicine (Baltimore), 98(18), e15337. https://doi.org/10.1097/MD.0000000000015337
  • Zhang, J., Huen, J., Lew, B., Chistopolskaya, K., Talib, M., Siau, C., & Leung, A. (2020). Depression, anxiety, and stress as a function of psychological strains: towards an etiological theory of mood disorders and psychopathologies. Journal of Affective Disorders, 271(2020), 279–285. https://doi.org/10.1016/j.jad.2020.03.076
  • Zhang, Y., Xiong, Y., Dong, J., Guo, T., Tang, X., & Zhao, Y. (2018). Caffeinated drinks intake, late chronotype, and increased body mass index among medical students in Chongqing, China: A multiple mediation model. International Journal of Environmental Research and Public Health, 15(8), 1–12. https://doi.org/10.3390/ijerph15081721
  • Zhao, C., Qiao, M. J., Wu, P. P., Li, N., & Xu, L. (2015). Anxiety and depression of medical college students and its risk. Occupation and Health, 31(12), 1691–1693. https://doi.org/10.13329/j.cnki.zyyjk.2015.0541
  • Zhong, X., Liu, Y., Pu, J., Tian, L., Gui, S., Song, X., Xu, S., Zhou, X., Wang, H., Zhou, W., Chen, J., Qi, X., & Xie, P. (2019). Depressive symptoms and quality of life among Chinese medical postgraduates: A national cross-sectional study. Psychology, Health & Medicine, 24(8), 1015–1027. https://doi.org/10.1080/13548506.2019.1626453

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.