2
Views
1
CrossRef citations to date
0
Altmetric
Research Article

Decreased Neurotropism of nef Long Terminal Repeat ( nef /LTR)-Deleted Simian Immunodeficiency Virus

, , , , , , & show all
Pages 442-451 | Published online: 10 Jul 2009

References

  • Adamson DC, Dawson TM, Zink MC, Clements JE, Dawson VL (1996). Neurovirulent simian immunodeficiency virus infection induces neuronal, endothelial, and glial apoptosis. Mo/ Med 2: 417–428.
  • Buchbinder SP, Katz MH, Hessol NA, O'Malley PM, Homberg SD (1994). Long-term HIV-1 infection without immunologic progression. AIDS 8: 1123–1128.
  • Churchill M, De castella I, Rhodes D, McPhee DA, Deacon N (2001). Evolution of promoter activities of attenuated strains of HIV-1. In: Proceedings of 13th Annual Confer-ence Australasian Society for HIV Medicine. Melbourne, Australia, p 50.
  • Clements JE, Anderson MG, Zink MC, Joag SV, Narayan 0 (1994). The SIV model of AIDS encephalopathy. Role of neurotropic viruses in diseases. In: HIV, AIDS and the brain. Price RW, Perry SW (eds). New York: Raven Press, pp 147–157.
  • Deacon NJ, Tsykin A, Solomon A, Smith K, Ludford-Menting M, Hooker DJ, McPhee DA, Greenway AL, Ellett A, Chatfield C (1995). Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients. Science 270: 988–991.
  • Demuth M, Czub S, Sauer U, Koutsilieri E, ten Haaft P, Heeney J, Stahl-Hennig C, ter Meulen V, Sopper S (2000). Relationship between viral load in blood, cerebrospinal fluid, brain tissue and isolated microglia with neurolog-ical disease in macaques infected with different strains of SIV. I NeuroVirol 6: 187–201.
  • Flaherty MT, Hauer DA, Mankowski JL, Zink MC, Clements JE (1997). Molecular and biological characterization of a neurovirulent molecular clone of simian immunodefi-ciency virus. J Virol 71: 5790–5798.
  • Iversen AK, Shpaer EG, Rodrgio AG, Hirsch MS, Walker BD, Sheppard HW, Merigan TC, Mullins JI (1995). Per-sistence of attenuated rev genes in a human immunode-ficiency virus type 1-infected asymptomatic indvidual. J Virol 69: 5743–5753.
  • Jin X, Bauer DE, Tuttleton SE, Lewin S, Gettie A, Blanchard J, Irwin CE, Safrit T, Mittler J, Weinberger L, Kostrikis LG, Zhang L, Perelson AS, Ho DD (1999). Dramatic rise in plasma viremia after CD8(±) T cell depletion in simian immunodeficiency virus-infected macaques. J Exp Med 189: 991–998.
  • Kent SJ, Dale CJ, Preiss S, Mills J, Campagna D, Purcell DF (2001). Vaccination with attenuated simian immunod-eficiency virus by DNA inoculation. J Virol 75: 11930–11934.
  • Kent SJ, Dale CJ, Preiss S, Purcell DF (2002). Evidence of recombination between 3' and 5' LTRs in macaques in-oculated with SW DNA. AIDS Res Hum Retroviruses 18: 227–230.
  • Kent SJ, Woodward A, Zhao A (1997). Human immunodefi-ciency virus type 1 (HIV-1)-specific T cell responses cor-relate with control of acute HIV-1 infection in macaques. I Infect Dis 176: 1188–1197.
  • Kent SJ, Zhao A, Best SJ, Chandler JD, Boyle DB, Ramshaw IA (1998). Enhanced T-cell immunogenicity and protec-tive efficacy of a human immunodeficiency virus type 1 vaccine regimen consisting of consecutive priming with DNA and boosting with recombinant fowlpox virus. J Virol 72: 10180–10188.
  • Kestler HW, Ringler DJ, Mori K, Panicali DL, Sehgal PK, Daniel MD, Desrosiers RC (1991). Importance of the nef gene for maintenance of high virus loads and for devel-opment of AIDS. Cell 65: 651–662.
  • Learmont JC, Geczy AF, Mills J, Ashton LJ, Raynes-Greenow CH, Garsia RJ, Dyer WB, McIntyre L, Oelrichs RB, Rhodes DI, Deacon NJ, Sullivan JS, McPhee DA, Crowe S, Solomon AE, Chatfield C, Cooke IR, Blasdall S, Kuipers H (1999). Immunologic and virologic status af-ter 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort. N Eng I Med 340: 1715–1722.
  • Mankowski JL, Flaherty MT, Spelman JP, Hauer DA, Didier PJ, Amedee AM, Murphey-Corb M, Kirstein LM, Munoz A, Clements JE, Zink MC (1997). Pathogenesis of simian immunodeficiency virus encephalitis: viral determi-nants of neurovirulence. J Virol 71: 6055–6060.
  • Mariani R, Kirchhoff F, Greenough TC, Sullivan JL, Desrosiers RC, Skowronski J (1996). High frequency of defective nef alleles in a long-term survivor with non-progressive human immunodeficiency virus type 1 in-fection. J Virol 70: 7752–7764.
  • Rhodes D, Solomon A, Bolton W, Wood J, Sullivan J, Learmont J, Deacon N (1999). Identification of a new recipient in the Sydney Blood Bank Cohort: a long-term HIV type 1-infected seroindeterminate individual. AIDS Res Hum Retroviruses 15: 1433–1439.
  • Rhodes DI, Ashton LJ, Solomon AE, Carr A, Cooper D, Kaldor J, Deacon NJ (2000). Characterization of three nef defective human immunodeficiency virus type 1 strains associated with long-term nonprogression. J Virol 74: 10581–10588.
  • Sacktor N, Lyles RH, Skolasky R, Kleeberger C, Selnes OA, Miller EN, Becker JT, Cohen B, McArthur JC, The Multicenter ACS (2001). HIV-associated neurologic dis-ease incidence changes: Multicenter AIDS Cohort Study, 1990–1998. Neurology 56: 257–260.
  • Salvi R, Garbuglia AR, Di Caro A, Pulciani S, Montella F, Benedetto A (1998). Grossly defective nef gene se-quences in a human immunodeficiency virus type-1 seropositive long-term nonprogressor. J Virol 72: 3646–3657.
  • von Herrath M, Oldstone MBA, Fox HS (1995). Simian immunodeficiency virus (SIV)-specific CTL in cere-brospinal fluid and brains of SIV-infected rhesus macaques. I Immunol 154: 5582–5589.
  • Zink MC, Amedee AM, Mankowski JL, Craig L, Didier PJ, Carter DL, Munoz A, Murphey-Corb M, Clements JE (1997). Pathogenesis of SIV encephalitis. Selection and replication of neurovirulent SW. Am I Pathol 151: 793–803.
  • Zink MC, Spelman JP, Robinson RB, Clements JE (1998). SIV infection of macaques—modeling the pro-gression to AIDS dementia. J NeuroVirol 4: 249–259.
  • Zink MC, Suryanarayana K, Mankowski JL, Shen A, Piatak M, Spelman JP, Carter DL, Adams RJ, Lifson JD, Clements JE (1999). High viral load in the cerebrospinal fluid and brain correlates with severity of simian im-munodeficiency virus encephalitis. J Virol 73: 10480–10488.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.