18
Views
0
CrossRef citations to date
0
Altmetric
Papers

The cellular transcription factor, CCAAT enhancer–binding protein alpha (C/EBP-α), has the potential to activate the bovine herpesvirus 1 immediate-early transcription unit 1 promoter

&
Pages 123-130 | Received 24 Jul 2008, Published online: 10 Jul 2009

References

  • Devireddy L, Zhang Y, Jones C. Cloning and initial characterization of an alternatively spliced transcript encoded by the bovine herpes virus 1 latency related (LR) gene. J NeuroVirol 2003; 9: 612–622
  • Devireddy L, Jones C. Alternative splicing of the latency-related transcript of bovine herpesvirus 1 yields RNAs containing unique open reading frames. J Virol 1998; 72: 7294–7301
  • Fraefel C, Zeng J, Choffat Y, Engels M, Schwyzer M, Ackermann M. Identification and zinc dependence of the bovine herpesvirus 1 transactivator protein BICP0. J Virol 1994; 68: 3154–3162
  • Hossain A, Schang LM, Jones C. Identification of gene products encoded by the latency-related gene of bovine herpesvirus 1. J Virol 1995; 69: 5345–5352
  • Huang J, Liao G, Chen H, Wu FY, Hutt-Fletcher L, Hayward GS, Hayward SD. Contribution of the C/EBP proteins to Epstein-Barr virus lytic gene expression and replication in epithelial cells. J Virol 2006; 80: 1098–1109
  • Inman M, Lovato L, Doster A, Jones C. A mutation in the latency-related gene of bovine herpesvirus 1 leads to impaired ocular shedding in acutely infected calves. J Virol 2001; 75: 8507–8515
  • Inman M, Lovato L, Doster A, Jones C. A mutation in the latency related gene of bovine herpesvirus 1 interferes with the latency-reactivation cycle of latency in calves. J Virol 2002; 76: 6771–6779
  • Inman M, Zhou J, Webb H, Jones C. Identification of a novel transcript containing a small open reading frame that is expressed during latency, and is antisense to the latency related gene of bovine herpes virus 1 (BHV-1). J Virol 2004; 78: 5438–5447
  • Jiang Y, Inman M, Zhang Y, Posadas NA, Jones C. A mutation in the latency related gene of bovine herpesvirus 1 (BHV-1) inhibits protein expression of a protein from open reading frame 2 (ORF-2) and an adjacent reading frame during productive infection. J Virol 2004; 78: 3184–3189
  • Jones C. Alphaherpesvirus latency: its role in disease and survival of the virus in nature. Adv Virus Res 1998; 51: 81–133
  • Jones C. Herpes simplex virus type 1 and bovine herpesvirus 1 latency. Clin Micro Rev 2003; 16: 79–95
  • Jones C, Chowdhury S. A review of the biology of bovine herpesvirus type 1 (BHV-1), its role as a cofactor in the bovine respiratory disease complex, and development of improved vaccines. Adv in Anim Health 2007; 8: 187–205
  • Lekstrom-Himes J, Xanthopoulos KG. Biological role of the CCAAT/enhancer binding protein family of transcription factors. J Biol Chem 1988; 273: 28545–28548
  • Lu R, Misra V. Potential role for luman, the cellular homologue of herpes simplex virus VP16 (alpha gene trans-inducing factor), in herpesvirus latency. J Virol 2000a; 74: 934–943
  • Lu R, Misra V. Zhangfei: a second cellular protein interacts with herpes simplex virus accessory factor HCF in a manner similar to Luman and VP16. Nucleic Acids Res 2000b; 28: 2446–2454
  • Meyer F, Perez S, Geiser V, Sintek M, Inman M, Jones C. A protein encoded by the bovine herpes virus 1 (BHV-1) latency related gene interacts with specific cellular regulatory proteins, including the CCAAT enhancer binding protein alpha (C/EBP-a). J Virol 2007; 81: 59–67
  • Misra V, Bratanich AC, Carpenter D, O'Hare P. Protein and DNA elements involved in transactivation of the promoter of the bovine herpesvirus (BHV) 1 IE-1 transcription unit by the BHV alpha gene trans-inducing factor. J Virol 1994; 68: 4898–4909
  • Misra V, Walker S, Hayes S, O'Hare P. The bovine herpesvirus alpha gene trans-inducing factor activates transcription by mechanisms different from those of its herpes simplex virus type 1 counterpart VP16. J Virol 1995; 69: 5209–5216
  • Misra V, Walter S, Yang P, Hayes S, O'Hare P. Conformational alteration of Oct-1 upon DNA binding dictates selectivity in differential interactions with related transcriptional coactivators. Mol Cell Biol 1996; 16: 4404–4413
  • Nerlov CA, Ziff EB. CCAAT/enhancer binding protein-alpha amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells. EMBO J 1995; 14: 4318–4328
  • Puthalakath H, O'Reilly LA, Gunn P, Lee L, Kelly PN, Huntington ND, Hughes PD, Michalak EM, McKrimm-Breschkin J, Motoyama N, Gotch T, Akira S, Bouillet P, Strasser A. ER stress triggers apoptotis by activating BH3-only protein Bim. Cell 2007; 129: 1337–1349
  • Ramji DP, Foka P. CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem J 2002; 365: 561–675
  • Rock DL, SL Beam, and JE Mayfield 1987. Mapping bovine herpesvirus type 1 latency-related RNA in trigeminal ganglia of latently infected rabbits. J Virol 61: 3827–31.
  • Tikkoo SK, Campos M, Babiuk LA. Bovine herpesvirus 1 (BHV-1): Biology, pathogenesis and control. Virus Res 1995; 45: 191–223
  • Wakenshae L, Walters MS, Whitehouse A. The herpesvirus saimiri replication and transcription activator acts synergistically with CCAAT enhancer binding protein alpha to activate the DNA polymerase promoter. J Virol 2005; 79: 13548–13560
  • Wang G, Goode T, Iakova P, Albrecht JH, Timchenko NA. C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arect. EMBO J 2002; 21: 930–941
  • Wang G, Timchenko NA. Dephosphorylated C/EBPalpha accelerated cell proliferation through sequestering retinoblastoma protein. Mol Cell Biol 2005; 25: 1325–1338
  • Wang GPI, Wilde M, Welm A, Goode T, Roesler WJ, Timchenko NA. C/EBPalpha arrests cell proliferation through direct interaction of Cdk2 and Cdk4. Mol Cell 2001; 8: 817–828
  • Wang SE, Wu FY, Yu Y, Hayward GS. CCAAT/enhancer-binding protein-alpha is induced during the early stages fo Kaposi's sarcoma-associated herpesvirus (KSHV) lytic cycle reactivation and together with the KSHV replication and transcription activator (RTA) cooperatively stimulates the viral RTA, MTA, and PAN promoters. J Virol 2003a; 77: 9590–9612
  • Wang SE, Wu FY, Yu Y, Hayward GS. CCAAT/enhancer-binding protein-alpha is induced during the early stages of Kaposi's sarcoma-associated herpesvirus (KSHV) lytic cycle reactivation and together with the KSHV replication and transcription activator (RTA) cooperatively stimulates the viral RTA, MTA, and PAN promoters. J Virol 2003b; 17: 9590–9612
  • Wedel A, LomsZeigler-Heitbrock HW. The C/EBP family of transcription factors. Immunolobiology 1995; 193: 171–185
  • Wirth UV, Fraefel C, Vogt B, Vlcek C, Paces V, Schwyzer M. Immediate-early RNA 2.9 and early RNA 2.6 of bovine herpesvirus 1 are 3' coterminal and encode a putative zinc finger transactivator protein. J Virol 1992; 66: 2763–2772
  • Wirth UV, Gunkel K, Engels M, Schwyzer M. Spatial and temporal distribution of bovine herpesvirus 1 transcripts. J Virol 1989; 63: 4882–4889
  • Wirth UV, Vogt B, Schwyzer M. The three major immediate-early transcripts of bovine herpesvirus 1 arise from two divergent and spliced transcription units. J Virol 1991; 65: 195–205
  • Wu FY, Wang SE, Chen H, Wang L, Hayward SD, Hayward GS. CCAAT/enhancer binding protein alpha binds to the Epstein-Barr virus (EBV) ZTA protein through oligomeric interactions and contributes to cooperative transcriptional activation of the ZTA promoter through direct binding to the ZII and ZIIIB motifs during productive infection of the EBV lytic cycle. J Virol 2004; 78: 4847–4865
  • Zhang Y, Jiang Y, Zhou J, Jones C. The bovine herpes virus 1 (BHV-1) immediate early protein (bICP0) interacts with the histone acetyltransferase p300, and these interactions correlate with stimulation of gC promoter activity. J Gen Virol 2006; 87: 1843–1851

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.