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General

The association between white matter hyperintensity volume and cognitive/physical decline in older people with dementia: A one-year longitudinal study

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Pages 2503-2510 | Received 04 Mar 2021, Accepted 08 Sep 2021, Published online: 27 Sep 2021

References

  • Ble, A., Ranzini, M., Zurlo, A., Menozzi, L., Atti, A. R., Munari, M. R., Volpato, S., Scaramelli, G., Fellin, R., & Zuliani, G. (2006). Leukoaraiosis is associated with functional impairment in older patients with Alzheimer’s disease but not vascular dementia. The Journal of Nutrition, Health & Aging, 10(1), 31–35.
  • Bossers, W. J., van der Woude, L. H., Boersma, F., Scherder, E. J., & van Heuvelen, M. J. (2012). Recommended measures for the assessment of cognitive and physical performance in older patients with dementia: A systematic review. Dementia and Geriatric Cognitive Disorders Extra, 2(1), 589–609. https://doi.org/10.1159/000345038
  • Bowie, C. R., & Harvey, P. D. (2006). Administration and interpretation of the Trail Making Test. Nature Protocols, 1(5), 2277–2281. https://doi.org/10.1038/nprot.2006.390
  • Bracco, L., Campani, D., Baratti, E., Lippi, A., Inzitari, D., Pracucci, G., & Amaducci, L. (1993). Relation between MRI features and dementia in cerebrovascular disease patients with leukoaraiosis: A longitudinal study. Journal of the Neurological Sciences, 120(2), 131–136. https://doi.org/10.1016/0022-510X(93)90263-X
  • Carmichael, O., Schwarz, C., Drucker, D., Fletcher, E., Harvey, D., Beckett, L., Jack, C. R., Jr., Weiner, M., DeCarli, C., & Alzheimer’s Disease Neuroimaging, I, Alzheimer’s Disease Neuroimaging Initiative. (2010). Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer Disease neuroimaging initiative. Archives of Neurology, 67(11), 1370–1378. https://doi.org/10.1001/archneurol.2010.284
  • Debette, S., Beiser, A., DeCarli, C., Au, R., Himali, J. J., Kelly-Hayes, M., Romero, J. R., Kase, C. S., Wolf, P. A., & Seshadri, S. (2010). Association of MRI markers of vascular brain injury with incident stroke, mild cognitive impairment, dementia, and mortality: The Framingham Offspring Study. Stroke, 41(4), 600–606. https://doi.org/10.1161/STROKEAHA.109.570044
  • Debette, S., & Markus, H. S. (2010). The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: Systematic review and meta-analysis. BMJ (Clinical Research ed.), 341, c3666. https://doi.org/10.1136/bmj.c3666
  • Deschaintre, Y., Richard, F., Leys, D., & Pasquier, F. (2009). Treatment of vascular risk factors is associated with slower decline in Alzheimer disease. Neurology, 73(9), 674–680. https://doi.org/10.1212/WNL.0b013e3181b59bf3
  • Fiford, C. M., Sudre, C. H., Pemberton, H., Walsh, P., Manning, E., Malone, I. B., Nicholas, J., Bouvy, W. H., Carmichael, O. T., Biessels, G. J., Cardoso, M. J., Barnes, J., & For The Alzheimer’s Disease Neuroimaging, I., for the Alzheimer’s Disease Neuroimaging Initiative. (2020). Automated white matter hyperintensity segmentation using Bayesian model selection: Assessment and correlations with cognitive change. Neuroinformatics, 18(3), 429–449. https://doi.org/10.1007/s12021-019-09439-6
  • Fischl, B. (2012). FreeSurfer. NeuroImage, 62(2), 774–781. https://doi.org/10.1016/j.neuroimage.2012.01.021
  • Glikmann-Johnston, Y., Oren, N., Hendler, T., & Shapira-Lichter, I. (2015). Distinct functional connectivity of the hippocampus during semantic and phonemic fluency. Neuropsychologia, 69, 39–49. https://doi.org/10.1016/j.neuropsychologia.2015.01.031
  • Habes, M., Erus, G., Toledo, J. B., Zhang, T., Bryan, N., Launer, L. J., Rosseel, Y., Janowitz, D., Doshi, J., Van der Auwera, S., von Sarnowski, B., Hegenscheid, K., Hosten, N., Homuth, G., Völzke, H., Schminke, U., Hoffmann, W., Grabe, H. J., & Davatzikos, C. (2016). White matter hyperintensities and imaging patterns of brain ageing in the general population. Brain, 139(4), 1164–1179. https://doi.org/10.1093/brain/aww008
  • Herbert, V., Brookes, R. L., Markus, H. S., & Morris, R. G. (2014). Verbal fluency in cerebral small vessel disease and Alzheimer’s disease. Journal of the International Neuropsychological Society: JINS, 20(4), 413–421. https://doi.org/10.1017/S1355617714000101
  • Jiang, J., Liu, T., Zhu, W., Koncz, R., Liu, H., Lee, T., Sachdev, P. S., & Wen, W. (2018). UBO Detector - A cluster-based, fully automated pipeline for extracting white matter hyperintensities. NeuroImage, 174, 539–549. https://doi.org/10.1016/j.neuroimage.2018.03.050
  • Kearney, F. C., Harwood, R. H., Gladman, J. R., Lincoln, N., & Masud, T. (2013). The relationship between executive function and falls and gait abnormalities in older adults: A systematic review. Dementia and Geriatric Cognitive Disorders, 36(1–2), 20–35. https://doi.org/10.1159/000350031
  • Lord, S. R., Menz, H. B., & Tiedemann, A. (2003). A physiological profile approach to falls risk assessment and prevention. Physical Therapy, 83(3), 237–252. https://doi.org/10.1093/ptj/83.3.237
  • McGuinness, B., Barrett, S. L., Craig, D., Lawson, J., & Passmore, A. P. (2010). Executive functioning in Alzheimer’s disease and vascular dementia. International Journal of Geriatric Psychiatry, 25(6), 562–568. https://doi.org/10.1002/gps.2375
  • Mioshi, E., Dawson, K., Mitchell, J., Arnold, R., & Hodges, J. R. (2006). The Addenbrooke’s Cognitive Examination Revised (ACE-R): A brief cognitive test battery for dementia screening. International Journal of Geriatric Psychiatry, 21(11), 1078–1085. https://doi.org/10.1002/gps.1610
  • Mungas, D., Harvey, D., Reed, B. R., Jagust, W. J., DeCarli, C., Beckett, L., Mack, W. J., Kramer, J. H., Weiner, M. W., Schuff, N., & Chui, H. C. (2005). Longitudinal volumetric MRI change and rate of cognitive decline. Neurology, 65(4), 565–571. https://doi.org/10.1212/01.wnl.0000172913.88973.0d
  • Mungas, D., Reed, B. R., Jagust, W. J., DeCarli, C., Mack, W. J., Kramer, J. H., Weiner, M. W., Schuff, N., & Chui, H. C. (2002). Volumetric MRI predicts rate of cognitive decline related to AD and cerebrovascular disease. Neurology, 59(6), 867–873. https://doi.org/10.1212/wnl.59.6.867
  • Nadkarni, N. K., McIlroy, W. E., Mawji, E., & Black, S. E. (2009). Gait and subcortical hyperintensities in mild Alzheimer’s disease and aging. Dementia and Geriatric Cognitive Disorders, 28(4), 295–301. https://doi.org/10.1159/000245158
  • Ngandu, T., Lehtisalo, J., Solomon, A., Levälahti, E., Ahtiluoto, S., Antikainen, R., Bäckman, L., Hänninen, T., Jula, A., Laatikainen, T., Lindström, J., Mangialasche, F., Paajanen, T., Pajala, S., Peltonen, M., Rauramaa, R., Stigsdotter-Neely, A., Strandberg, T., Tuomilehto, J., Soininen, H., & Kivipelto, M. (2015). A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): A randomised controlled trial. The Lancet, 385(9984), 2255–2263. https://doi.org/10.1016/S0140-6736(15)60461-5
  • Ogama, N., Sakurai, T., Nakai, T., Niida, S., Saji, N., Toba, K., Umegaki, H., & Kuzuya, M. (2017). Impact of frontal white matter hyperintensity on instrumental activities of daily living in elderly women with Alzheimer disease and amnestic mild cognitive impairment. PLOS One, 12(3), e0172484. https://doi.org/10.1371/journal.pone.0172484
  • Ogama, N., Sakurai, T., Shimizu, A., & Toba, K. (2014). Regional white matter lesions predict falls in patients with amnestic mild cognitive impairment and Alzheimer’s disease. Journal of the American Medical Directors Association, 15(1), 36–41. https://doi.org/10.1016/j.jamda.2013.11.004
  • Papp, K. V., Kaplan, R. F., Springate, B., Moscufo, N., Wakefield, D. B., Guttmann, C. R. G., & Wolfson, L. (2014). Processing speed in normal aging: Effects of white matter hyperintensities and hippocampal volume loss. Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition, 21(2), 197–213. https://doi.org/10.1080/13825585.2013.795513
  • Patterson, C. (2018). World Alzheimer report 2018. London: Alzheimer’s Disease International.
  • Prins, N. D., & Scheltens, P. (2015). White matter hyperintensities, cognitive impairment and dementia: An update. Nature Reviews. Neurology, 11(3), 157–165. https://doi.org/10.1038/nrneurol.2015.10
  • Puzo, C., Labriola, C., Sugarman, M. A., Tripodis, Y., Martin, B., Palmisano, J. N., Steinberg, E. G., Stein, T. D., Kowall, N. W., McKee, A. C., Mez, J., Killiany, R. J., Stern, R. A., & Alosco, M. L. (2019). Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer’s Coordinating Center Uniform Data Set. Alzheimer’s Research & Therapy, 11(1), 64. https://doi.org/10.1186/s13195-019-0521-0
  • Richard, F., & Pasquier, F. (2012). Can the treatment of vascular risk factors slow cognitive decline in Alzheimer’s disease patients? Journal of Alzheimer’s Disease: JAD, 32(3), 765–772. https://doi.org/10.3233/JAD-2012-121012
  • Sarro, L., Tosakulwong, N., Schwarz, C. G., Graff-Radford, J., Przybelski, S. A., Lesnick, T. G., Zuk, S. M., Reid, R. I., Raman, M. R., Boeve, B. F., Ferman, T. J., Knopman, D. S., Comi, G., Filippi, M., Murray, M. E., Parisi, J. E., Dickson, D. W., Petersen, R. C., Jack, C. R., Jr, & Kantarci, K. (2017). An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer’s disease. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 13(3), 257–266. https://doi.org/10.1016/j.jalz.2016.07.003
  • Skoog, I., Berg, S., Johansson, B., Palmertz, B., & Andreasson, L. A. (1996). The influence of white matter lesions on neuropsychological functioning in demented and non-demented 85-year-olds. Acta Neurologica Scandinavica, 93(2–3), 142–148. https://doi.org/10.1111/j.1600-0404.1996.tb00190.x
  • Smith, E. E., O’Donnell, M., Dagenais, G., Lear, S. A., Wielgosz, A., Sharma, M., Poirier, P., Stotts, G., Black, S. E., Strother, S., Noseworthy, M. D., Benavente, O., Modi, J., Goyal, M., Batool, S., Sanchez, K., Hill, V., McCreary, C. R., Frayne, R., … Investigators, P, PURE Investigators. (2015). Early cerebral small vessel disease and brain volume, cognition, and gait. Annals of Neurology, 77(2), 251–261. https://doi.org/10.1002/ana.24320
  • Taylor, M. E., Boripuntakul, S., Toson, B., Close, J. C. T., Lord, S. R., Kochan, N. A., Sachdev, P. S., Brodaty, H., & Delbaere, K. (2019). The role of cognitive function and physical activity in physical decline in older adults across the cognitive spectrum. Aging & Mental Health, 23(7), 863–871. https://doi.org/10.1080/13607863.2018.1474446
  • Taylor, M. E., Delbaere, K., Lord, S. R., Mikolaizak, A. S., Brodaty, H., & Close, J. C. T. (2014). Neuropsychological, physical, and functional mobility measures associated with falls in cognitively impaired older adults. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 69(8), 987–995. https://doi.org/10.1093/gerona/glt166
  • Taylor, M. E., Lord, S. R., Delbaere, K., Wen, W., Jiang, J. Y., Brodaty, H., Kurrle, S. E., Mikolaizak, A. S., & Close, J. C. T. (2019). White matter hyperintensities are associated with falls in older people with dementia. Brain Imaging and Behavior, 13(5), 1265–1272. https://doi.org/10.1007/s11682-018-9943-8
  • Tian, Q., An, Y., Resnick, S. M., & Studenski, S. (2017). The relative temporal sequence of decline in mobility and cognition among initially unimpaired older adults: Results from the Baltimore Longitudinal Study of Aging. Age & Ageing, 46(3), 445–451. https://doi.org/10.1093/ageing/afw185
  • Tombaugh, T. N. (2004). Trail making test A and B: Normative data stratified by age and education. Archives of Clinical Neuropsychology, 19(2), 203–214. https://doi.org/10.1016/S0887-6177(03)00039-8
  • van Dalen Jan, W., Moll van Charante, E. P., Caan Matthan, W. A., Scheltens, P., Majoie Charles, B. L. M., Nederveen Aart, J., van Gool Willem, A., & Richard, E. (2017). Effect of long-term vascular care on progression of cerebrovascular lesions: Magnetic resonance imaging substudy of the PreDIVA Trial (Prevention of Dementia by Intensive Vascular Care). Stroke, 48(7), 1842–1848. https://doi.org/10.1161/STROKEAHA.117.017207
  • van den Berg, E., Geerlings, M. I., Biessels, G. J., Nederkoorn, P. J., & Kloppenborg, R. P. (2018). White matter hyperintensities and cognition in mild cognitive impairment and Journal of Alzheimer’s Disease, 63(2), 515–527. https://doi.org/10.3233/JAD-170573
  • Weakley, A., & Schmitter-Edgecombe, M. (2014). Analysis of verbal fluency ability in Alzheimer’s disease: The role of clustering, switching and semantic proximities. Archives of Clinical Neuropsychology: The Official Journal of the National Academy of Neuropsychologists, 29(3), 256–268. https://doi.org/10.1093/arclin/acu010
  • White, W. B., Wakefield, D. B., Moscufo, N., Guttmann, C. R. G., Kaplan, R. F., Bohannon, R. W., Fellows, D., Hall, C. B., & Wolfson, L. (2019). Effects of intensive versus standard ambulatory blood pressure control on cerebrovascular outcomes in older people (INFINITY). Circulation, 140(20), 1626–1635. https://doi.org/10.1161/CIRCULATIONAHA.119.041603
  • Zheng, J. J., Delbaere, K., Close, J. C., Sachdev, P. S., & Lord, S. R. (2011). Impact of white matter lesions on physical functioning and fall risk in older people: a systematic review. Stroke, 42(7), 2086–2090. https://doi.org/10.1161/STROKEAHA.110.610360
  • Zheng, J. J., Delbaere, K., Close, J. C., Sachdev, P., Wen, W., Brodaty, H., & Lord, S. R. (2012). White matter hyperintensities are an independent predictor of physical decline in community-dwelling older people. Gerontology, 58(5), 398–406. https://doi.org/10.1159/000337815

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