4,757
Views
11
CrossRef citations to date
0
Altmetric
Hematology

Systematic review and analysis of efficacy of recombinant factor IX products for prophylactic treatment of hemophilia B in comparison with rIX-FP

, , , , &
Pages 1014-1021 | Received 18 Apr 2019, Accepted 07 May 2019, Published online: 05 Jun 2019

References

  • Srivastava A, Brewer AK, Mauser-Bunschoten EP, et al. Guidelines for the management of hemophilia. Haemophilia. 2013;19:e1–47.
  • Franchini M. Current management of hemophilia B: recommendations, complications and emerging issues. Expert Rev Hematol. 2014;7:573–581.
  • Forsyth AL, Rivard GE, Valentino LA, et al. Consequences of intra-articular bleeding in haemophilia: science to clinical practice and beyond. Haemophilia. 2012;18:112–119.
  • Djambas Khayat C. Once-weekly prophylactic dosing of recombinant factor IX improves adherence in hemophilia B. J Blood Med. 2016;7:275–282.
  • Ljung R, Gretenkort Andersson N. The current status of prophylactic replacement therapy in children and adults with haemophilia. Br J Haematol. 2015;169:777–786.
  • Mahdi AJ, Obaji SG, Collins PW. Role of enhanced half-life factor VIII and IX in the treatment of haemophilia. Br J Haematol. 2015;169:768–776.
  • Mannucci PM, Franchini M. Emerging drugs for hemophilia B. Expert Opin Emerg Drugs. 2014;19:407–414.
  • Santagostino E, Martinowitz U, Lissitchkov T, et al. Long-acting recombinant coagulation factor IX albumin fusion protein (rIX-FP) in hemophilia B: results of a phase 3 trial. Blood. 2016;127:1761–1769.
  • Powell JS, Pasi KJ, Ragni MV, et al. Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B. N Engl J Med. 2013;369:2313–2323.
  • Collins PW, Young G, Knobe K, et al. Recombinant long-acting glycoPEGylated factor IX in hemophilia B: a multinational randomized phase 3 trial. Blood. 2014;124:3880–3886.
  • Iorio A, Krishnan S, Myren KJ, et al. Continuous prophylaxis with recombinant factor IX Fc fusion protein and conventional recombinant factor IX products: comparisons of efficacy and weekly factor consumption. J Med Econ. 2017;20:337–344.
  • Higgins J, Deeks J. Chapter 7: Selecting studies and collecting data. In: Higgins J, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011): The Cochrane Collaboration. Chichester, England: John Wiley & Sons, Ltd.; 2011.
  • Lambert T, Recht M, Valentino LA, et al. Reformulated BeneFix: efficacy and safety in previously treated patients with moderately severe to severe haemophilia B. Haemophilia. 2007;13:233–243.
  • Oldenburg J, Carcao M, Lentz SR, et al. Once-weekly prophylaxis with 40 IU/kg nonacog beta pegol (N9-GP) achieves trough levels of >15% in patients with haemophilia B: pooled data from the paradigm trials. Haemophilia. 2018;24:911–920.
  • Kavakli K, Smith L, Kuliczkowski K, et al. Once-weekly prophylactic treatment vs. on-demand treatment with nonacog alfa in patients with moderately severe to severe haemophilia B. Haemophilia. 2016;22:381–388.
  • Windyga J, Lissitchkov T, Stasyshyn O, et al. Pharmacokinetics, efficacy and safety of BAX326, a novel recombinant factor IX: a prospective, controlled, multicentre phase I/III study in previously treated patients with severe (FIX level <1%) or moderately severe (FIX level </=2%) haemophilia B. Haemophilia. 2014;20:15–24.
  • Solano Trujillo MH, Stasyshyn O, Rusen L, et al. Safe switching from a pdFIX (Immunine®) to a rFIX (Bax326). Haemophilia. 2014;20:674–681.
  • Collins PW, Quon DVK, Makris M, et al. Pharmacokinetics, safety and efficacy of a recombinant factor IX product, trenonacog alfa in previously treated haemophilia B patients. Haemophilia. 2018;24:104–112.
  • Hacker MR, Geraghty S, Manco-Johnson M. Barriers to compliance with prophylaxis therapy in haemophilia. Haemophilia. 2001;7:392–396.
  • Armstrong EP, Malone DC, Krishnan S, et al. Adherence to clotting factors among persons with hemophilia A or B. Hematology. 2015;20:148–153.
  • Yeung CH, Santesso N, Pai M, et al. Care models in the management of haemophilia: a systematic review. Haemophilia. 2016;22:31–40.