Comprehensive assessment of patients with irritable bowel syndrome with constipation and chronic idiopathic constipation using deterministically linked administrative claims and patient-reported data: the Chronic Constipation and IBS-C Treatment and Outcomes Real-World Research Platform (CONTOR)

References

• Lacy BE, Mearin F, Chang L, et al. Bowel disorders. Gastroenterology. 2016;150(6):1393.e5–1407.e5.
   Web of Science ®Google Scholar
• Irvine EJ, Ferrazzi S, Pare P, et al. Health-related quality of life in functional GI disorders: focus on constipation and resource utilization. Am J Gastroenterology. 2002;97(8):1986–1993.
   PubMed Web of Science ®Google Scholar
• Dean BB, Aguilar D, Barghout V, et al. Impairment in work productivity and health-related quality of life in patients with IBS. Am J Manag Care. 2005;11(1 Suppl):S17–S26.
   PubMed Web of Science ®Google Scholar
• Ballou S, McMahon C, Lee HN, et al. Effects of irritable bowel syndrome on daily activities vary among subtypes based on results from the IBS in America survey. Clin Gastroenterol Hepatol. 2019;17(12):2471.e3–2478.e3.
   Web of Science ®Google Scholar
• Doshi JA, Cai Q, Buono JL, et al. Economic burden of irritable bowel syndrome with constipation: a retrospective analysis of health care costs in a commercially insured population. J Manag Care Spec Pharm. 2014;20(4):382–390.
   PubMed Web of Science ®Google Scholar
• Cai Q, Buono JL, Spalding WM, et al. Healthcare costs among patients with chronic constipation: a retrospective claims analysis in a commercially insured population. J Med Econ. 2014;17(2):148–158.
   PubMedGoogle Scholar
• Reilly MC, Bracco A, Ricci JF, et al. The validity and accuracy of the Work Productivity and Activity Impairment Questionnaire–Irritable Bowel Syndrome version (WPAI:IBS). Aliment Pharmacol Ther. 2004;20(4):459–467.
   PubMed Web of Science ®Google Scholar
• Dennison C, Prasad M, Lloyd A, et al. The health-related quality of life and economic burden of constipation. Pharmacoeconomics. 2005;23(5):461–476.
   PubMed Web of Science ®Google Scholar
• Quigley EMM, Horn J, Kissous-Hunt M, et al. Better Understanding and Recognition of the Disconnects, Experiences, and Needs of Patients with Irritable Bowel Syndrome with Constipation (BURDEN IBS-C) study: results of an online questionnaire. Adv Ther. 2018;35(7):967–980.
   PubMed Web of Science ®Google Scholar
• Harris LA, Horn J, Kissous-Hunt M, et al. The Better Understanding and Recognition of the Disconnects, Experiences, and Needs of Patients with Chronic Idiopathic Constipation (BURDEN-CIC) study: results of an online questionnaire. Adv Ther. 2017;34(12):2661–2673.
   PubMed Web of Science ®Google Scholar
• Johnson CL, Dohmann SM, Burt VL, et al. National health and nutrition examination survey: sample design, 2011–2014. National Center for Health Statistics. Vital Health Stat. 2014;2:162.
   Google Scholar
• American Association for Public Opinion Research. Standard definitions: final dispositions of case codes and outcome rates for surveys. 9th ed. 2016 [Accessed 2019 Sep 17]. Available from: http://www.aapor.org/AAPOR_Main/media/publications/Standard-Definitions20169theditionfinal.pdf.
   Google Scholar
• Frank L, Kleinman L, Farup C, et al. Psychometric validation of a constipation symptom assessment questionnaire. Scand J Gastroenterol. 1999;34(9):870–877.
   PubMed Web of Science ®Google Scholar
• Marquis P, De La Loge C, Dubois D, et al. Development and validation of the patient assessment of constipation quality of life questionnaire. Scand J Gastroenterol. 2005;40(5):540–551.
   PubMed Web of Science ®Google Scholar
• Reilly MC, Zbrozek AS, Dukes EM. The validity and reproducibility of a work productivity and activity impairment instrument. Pharmacoeconomics. 1993;4(5):353–365.
   PubMed Web of Science ®Google Scholar
• Quan H, Li B, Couris CM, et al. Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am J Epidemiol. 2011;173(6):676–682.
   PubMed Web of Science ®Google Scholar
• US Bureau of Labor Statistics. Consumer price index. Medical care; 2014 [Accessed 2017]. Available from https://www.bls.gov/cpi/data.htm.
   Google Scholar
• Johanson JF, Kralstein J. Chronic constipation: a survey of the patient perspective. Aliment Pharmacol Ther. 2007;25(5):599–608.
   PubMed Web of Science ®Google Scholar
• Herrick LM, Spalding WM, Saito YA, et al. A case-control comparison of direct healthcare-provider medical costs of chronic idiopathic constipation and irritable bowel syndrome with constipation in a community-based cohort. J Med Econ. 2017;20(3):273–279.
   PubMed Web of Science ®Google Scholar
• Chey WD, Kurlander J, Eswaran S. Irritable bowel syndrome: a clinical review. JAMA. 2015;313(9):949–958.
   PubMed Web of Science ®Google Scholar
• McKenzie YA, Bowyer RK, Leach H, et al. British Dietetic Association systematic review and evidence-based practice guidelines for the dietary management of irritable bowel syndrome in adults (2016 update). J Hum Nutr Diet. 2016;29(5):549–575.
   PubMed Web of Science ®Google Scholar
• Sonu I, Triadafilopoulos G, Gardner JD. Persistent constipation and abdominal adverse events with newer treatments for constipation. BMJ Open Gastroenterol. 2016;3(1):e000094
   PubMed Web of Science ®Google Scholar
• McCormick D. Managing costs and care for chronic idiopathic constipation. Am J Manag Care. 2019;25(4 Suppl):S63–S69.
   PubMed Web of Science ®Google Scholar
• Guerin A, Carson RT, Lewis B, et al. The economic burden of treatment failure amongst patients with irritable bowel syndrome with constipation or chronic constipation: a retrospective analysis of a Medicaid population. J Med Econ. 2014;17(8):577–586.
   PubMedGoogle Scholar
• Cash BD. Understanding and managing IBS and CIC in the primary care setting. Gastroenterol Hepatol (N Y). 2018;14(5 Suppl 3):3–15.
   PubMedGoogle Scholar
• Bharucha AE, Dorn SD, Lembo A, et al. American Gastroenterological Association medical position statement on constipation. Gastroenterology. 2013;144(1):211–217.
   PubMed Web of Science ®Google Scholar
• Tse Y, Armstrong D, Andrews CN, et al. Treatment algorithm for chronic idiopathic constipation and constipation-predominant irritable bowel syndrome derived from a Canadian national survey and needs assessment on choices of therapeutic agents. Can J Gastroenterol Hepatol. 2017;2017:8612189.
   PubMed Web of Science ®Google Scholar
• Buono JL, Tourkodimitris S, Sarocco P, et al. Impact of linaclotide treatment on work productivity and activity impairment in adults with irritable bowel syndrome with constipation: results from 2 randomized, double-blind, placebo-controlled phase 3 trials. Am Health Drug Benefits. 2014;7(5):289–297.
   PubMedGoogle Scholar
• Solem CT, Patel H, Mehta S, et al. Treatment patterns, symptom reduction, quality of life, and resource use associated with lubiprostone in irritable bowel syndrome constipation subtype. Curr Med Res Opin. 2016;32(5):899–905.
   PubMed Web of Science ®Google Scholar
• Taylor DC, Abel JL, Bancroft T, et al. Health care resource use and costs pre- and post-treatment initiation with linaclotide: Retrospective analyses of a U.S. insured population. Manag Care. 2018;27(2):33–40.
   PubMedGoogle Scholar
• DiBonaventura M, Sun SX, Bolge SC, et al. Health-related quality of life, work productivity and health care resource use associated with constipation predominant irritable bowel syndrome. Curr Med Res Opin. 2011;27(11):2213–2222.
   PubMed Web of Science ®Google Scholar
• Heidelbaugh JJ, Stelwagon M, Miller SA, et al. The spectrum of constipation-predominant irritable bowel syndrome and chronic idiopathic constipation: US survey assessing symptoms, care seeking, and disease burden. Am J Gastroenterol. 2015;110(4):580–587.
   PubMed Web of Science ®Google Scholar
• Sun SX, Dibonaventura M, Purayidathil FW, et al. Impact of chronic constipation on health-related quality of life, work productivity, and healthcare resource use: an analysis of the National Health and Wellness Survey. Dig Dis Sci. 2011;56(9):2688–2695.
   PubMed Web of Science ®Google Scholar
• Stephenson JJ, Buono JL, Spalding WM, et al. Impact of irritable bowel syndrome with constipation on work productivity and daily activity among commercially insured patients in the United States. Value Health. 2014;17(7):A370.
   PubMed Web of Science ®Google Scholar
• Mitra D, Davis KL, Baran RW. All-cause health care charges among managed care patients with constipation and comorbid irritable bowel syndrome. Postgrad Med. 2011;123(3):122–132.
   PubMed Web of Science ®Google Scholar
• Mauri M, Elli T, Caviglia G, et al. RAWGraphs: a visualisation platform to create open outputs. Proceedings of the 12th Biannual Conference on Italian SIGCHI Chapter. Vol 28. New York, NY: ACM; 2017. p. 1–5.
   Google Scholar