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Influence of phytoestrogens on endometrial thickness: a systematic review and meta-analysis

, , ORCID Icon, ORCID Icon & ORCID Icon
Pages 118-127 | Received 13 Jan 2021, Accepted 21 Apr 2021, Published online: 26 May 2021

References

  • North American Menopause Society. The 2012 hormone therapy position statement of: the North American Menopause Society. Menopause. 2012;19(3):257–271.
  • Suwanvesh N, Manonai J, Sophonsritsuk A, et al. Comparison of Pueraria mirifica gel and conjugated equine estrogen cream effects on vaginal health in postmenopausal women. Menopause. 2017;24(2):210–215.
  • The American College of Obstetricians and Gynecologists. Practice bulletin no. 141: management of menopausal symptoms. Obstet Gynecol. 2014;123(1):202–216.
  • Jameson JL, de Kretser DM, Marshall JC, et al. Reproductive endocrinology: adult and pediatric endocrinology. Amsterdam, Netherlands: Elsevier Health Sciences; 2013.
  • Moore TR, Franks RB, Fox C. Review of efficacy of complementary and alternative medicine treatments for menopausal symptoms. J Midwifery. 2017;62(3):286–297.
  • Sathyapalan T, Aye M, Rigby AS, et al. Soy reduces bone turnover markers in women during early menopause: a randomized controlled trial. J Bone Miner Res. 2017;32(1):157–164.
  • Quaas AM, Kono N, Mack WJ, et al. Effect of isoflavone soy protein supplementation on endometrial thickness, hyperplasia, and endometrial cancer risk in postmenopausal women. Menopause. 2013;20:840–844.
  • Dastjerdi MV, Eslami B, Sharifi MA, et al. Effect of soy isoflavone on hot flushes, endometrial thickness, and breast clinical as well as sonographic features. Iran J Public Health. 2018;47(3):382–389.
  • Kuiper GG, Lemmen JG, Carlsson B, et al. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β. Endocrinology. 1998;139(10):4252–4263.
  • DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177–188.
  • Cheng WC, Lo SC, Tsai KS, et al. Effects of high-dose phytoestrogens on circulating cellular microparticles and coagulation function in postmenopausal women. J Formos Med Assoc. 2007;114(8):710–716.
  • Colacurci N, Franciscis PD, Atlante M, et al. Endometrial, breast and liver safety of soy isoflavones plus Lactobacillus sporogenes in post-menopausal women. Gynecol Endocrinol. 2013;29(3):209–212.
  • Colli MC, Bracht A, Soares AA, et al. Evaluation of the efficacy of flaxseed meal and flaxseed extract in reducing menopausal symptoms. J Med Food. 2012;15(9):840–845.
  • D'Anna R, Cannata ML, Marini H, et al. Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women: a 2-year randomized, double-blind, placebo-controlled study. Menopause. 2009;16(2):301–306.
  • Imhof M, Gocan A, Reithmayr F, et al. Effects of a red clover extract (MF11RCE) on endometrium and sex hormones in postmenopausal women. Maturitas. 2006;55(1):76–81.
  • Marini H, Bitto A, Altavilla D, et al. Breast safety and efficacy of genistein aglycone for postmenopausal bone loss: a follow-up study. J Clin Endocrinol Metab. 2008;93(12):4784–4796.
  • Manonai J, Chittacharoen A, Udomsubpayakul U, et al. Effects and safety of Pueraria mirifica on lipid profiles and biochemical markers of bone turnover rates in healthy postmenopausal women. Menopause. 2008;15(3):530–535.
  • Penotti M, Fabio E, Modena AB, et al. Effect of soy-derived isoflavones on hot flushes, endometrial thickness, and the pulsatility index of the uterine and cerebral arteries. Fertil Steril. 2003;79(5):1112–1117.
  • Mareti E, Abatzi C, Vavilis D, et al. Effect of oral phytoestrogens on endometrial thickness and breast density of perimenopausal and postmenopausal women: a systematic review and meta-analysis. Maturitas. 2019;124:81–88.
  • Murray MJ, Meyer WR, Lessey BA, et al. Soy protein isolate with isoflavones does not prevent estradiol-induced endometrial hyperplasia in postmenopausal women: a pilot trial. Menopause. 2003;10(5):456–464.
  • Smith-Bindman R, Kerlikowske K, Feldstein VA, et al. Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities. JAMA. 1998;280(17):1510–1517.
  • Sanderson PA, Critchley HOD, Williams ARW, et al. New concepts for an old problem: the diagnosis of endometrial hyperplasia: the diagnosis of endometrial hyperplasia. Hum Reprod Update. 2017;23(2):232–254.
  • Tabor A, Watt HC, Wald NJ. Endometrial thickness as a test for endometrial cancer in women with postmenopausal vaginal bleeding. Obstet Gynecol. 2002;99(4):663–670.
  • Sammartino A, Di Carlo C, Mandato VD, et al. Effects of Genistein on the Endometrium: Ultrasonographic Evaluation. Gynecol Endocrinol. 2003;17(1):45–49.
  • Palacios S, Pornel B, Bergeron C, et al. Endometrial safety assessment of a specific and standardized soy extract according to international guidelines. Menopause. 2007;14(6):1006–1011.
  • Brinton LA, Trabert B, Anderson GL, et al. Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal women. Cancer Epidemiol Biomarkers Prev. 2016;25(7):1081–1089.
  • Adlercreutz H, Bannwart C, Wähälä K, et al. Inhibition of human aromatase by mammalian lignans and isoflavonoid phytoestrogens. J Steroid Biochem Mol Biol. 1993;44(2):147–153.
  • Poluzzi E, Piccinni C, Raschi E, et al. Phytoestrogens in postmenopause: the state of the art from a chemical, pharmacological and regulatory perspective. Curr Med Chem. 2013;21(4):417–436.
  • Alekel DL, Genschel U, Koehler KJ, et al. Soy isoflavones for reducing bone loss study: effects of a 3-year trial on hormones, adverse events, and endometrial thickness in postmenopausal women. Menopause. 2015;22(2):185–197.
  • Willhite LA, O'Connell MB. Urogenital atrophy: prevention and treatment: prevention and treatment. Pharmacotherapy. 2001;21(4):464–480.
  • Portman DJ, Gass MLS. Genitourinary syndrome of menopause: new terminology for vulvovaginal atrophy from the International Society for the Study of Women’s Sexual Health and The North American Menopause Society. Menopause. 2014;21(10):1063–1068.
  • Dizavandi FR, Ghazanfarpour M, Roozbeh N, et al. An overview of the phytoestrogen effect on vaginal health and dyspareunia in peri- and post-menopausal women. Post Reprod Health. 2019;25(1):11–20.
  • Wu AH, Yu MC, Tseng CC, et al. Epidemiology of soy exposures and breast cancer risk. Br J Cancer. 2008;98(1):9–14.
  • Maskarinec G, Verheus M, Steinberg FM, et al. Various doses of soy isoflavones do not modify mammographic density in postmenopausal women. J Nutr. 2009;139(5):981–986.
  • Anderson JW, Bush HM. Soy protein effects on serum lipoproteins: a quality assessment and meta-analysis of randomized, controlled studies: a quality assessment and meta-analysis of randomized, controlled studies. J Am Coll Nutr. 2011;30(2):79–91.
  • Teede HJ, Dalais FS, Kotsopoulos D, et al. Dietary soy has both beneficial and potentially adverse cardiovascular effects: a placebo-controlled study in men and postmenopausal women: a placebo-controlled study in men and postmenopausal women1. J Clin Endocrinol Metab. 2001;86(7):3053–3060.
  • Nikander E, Tiitinen A, Laitinen K, et al. Effects of isolated isoflavonoids on lipids, lipoproteins, insulin sensitivity, and ghrelin in postmenopausal women. J Clin Endocrinol Metab. 2004;89(7):3567–3572.
  • Siepmann T, Roofeh J, Kiefer FW, et al. Hypogonadism and erectile dysfunction associated with soy product consumption. Nutrition. 2011;27(7-8):859–862.

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