The influence of stimulus eccentricity on prosaccade outcomes in patients with Alzheimer’s Disease dementia at an early stage and amnestic mild cognitive impairment

References

• Abel, L. A., Unverzagt, F., & Yee, R. D. (2002). Effects of stimulus predictability and interstimulus gap on saccades in Alzheimer's disease. Dementıa Geriatrıc Cognıtıve Disorders, 13(4), 235–243. https://doi.org/10.1159/000057702
   PubMed Web of Science ®Google Scholar
• Adler, F. H., & Fliegelman, M. (1934). Influence of fixation on the visual acuity. Archives of Ophthalmology, 12(4), 475–483. https://doi.org/10.1001/archopht.1934.00830170013002
   Google Scholar
• Albert, M. S., DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., Gamst, A., Holtzman, D. M., Jagust, W. J., Petersen, R. C., Snyder, P. J., Carillo, M. C., Thies, B., & Phelps, C. H. (2011a). The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimer’s & Dementia, 7(3), 270–279. https://doi.org/10.1159/000057702
   PubMed Web of Science ®Google Scholar
• Albert, M. S., DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., Gamst, A., Holtzman, D. M., Jagust, W. J., Petersen, R. C., Snyder, P. J., Carillo, M. C., Thies, B., & Phelps, C. H. (2011b). The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the national institute on Aging-Alzheimer’s association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimer’s & Dementia, 7(3), 270–279. https://doi.org/10.1016/j.jalz.2011.03.008
   PubMed Web of Science ®Google Scholar
• Alichniewicz, K. K., Brunner, F., Klünemann, H. H., & Greenlee, M. W. (2013). Neural correlates of saccadic inhibition in healthy elderly and patients with amnestic mild cognitive impairment. Frontiers in Psychology, 4(Article), 467. https://doi.org/10.3389/fpsyg.2013.00467
   PubMedGoogle Scholar
• Anderson, T. J., & MacAskill, M. R. (2013). Eye movements in patients with neurodegenerative disorders. Nature Reviews Neurology, 9(2), 74–85. https://doi.org/10.1038/nrneurol.2012.273
   PubMed Web of Science ®Google Scholar
• Anjum, J., & Hallowell, B. (2019). Validity of an eyetracking method for capturing auditory-visual cross-format semantic priming. Journal of Clinical and Experimental Neuropsychology, 41(4), 411–431. https://doi.org/10.1080/13803395.2019.1567692
   PubMed Web of Science ®Google Scholar
• Badler, J. B., Heinen, S. J., Abel, L. A., Unverzagt, F., & Yee, R. D. (2006). Anticipatory movement timing using prediction and external cues. Journal of Neuroscience, 26(17), 4519–4525. https://doi.org/10.1523/JNEUROSCI.3739-05.2006
   PubMed Web of Science ®Google Scholar
• Benton, A. L., & Van Allen, M. W. (1968). Impairment in facial recognition in patients with cerebral disease. Cortex, 4(4), 344–358. 80018-8. https://doi.org/10.1016/S0010-9452(68)
   Google Scholar
• Benton, A. L., Varney, N. R., & Hamsher, K. (1978). Visuospatial judgment: Clinical test. Archives of Neurology, 35(6), 364–367. https://doi.org/10.1001/archneur.1978.00500300038006
   PubMedGoogle Scholar
• Berg, E. A. (1948). A simple objective technique for measuring flexibility in thinking. The Journal of General Psychology, 39(1), 15–22. https://doi.org/10.1080/00221309.1948.9918159
   PubMed Web of Science ®Google Scholar
• Berger, A., Henik, A., & Rafal, R. (2005). Competition between endogenous and exogenous orienting of visual attention. Journal of Experimental Psychology: General, 134(2), 207–221. https://doi.org/10.1037/0096-3445.134.2.207
   PubMed Web of Science ®Google Scholar
• Boxer, A. L., Garbutt, S., Rankin, K. P., Hellmuth, J., Neuhaus, J., Miller, B. L., & Lisberger, S. G. (2006). Medial versus Lateral Frontal Lobe Contributions to Voluntary Saccade Control as Revealed by the Study of Patients with Frontal Lobe Degeneration. The Journal of Neuroscience, 26(23), 6354–6363. https://doi.org/10.1523/jneurosci.0549-06.2006
   Google Scholar
• Boxer, A. L., Garbutt, S., Seeley, W. W., Jafari, A., Heuer, H. W., Mirsky, J., Hellmuth, J., Trojanowski, J. Q., Huang, E., DeArmond, S., Neuhaus, J., & Miller, B. L. (2012). Saccade abnormalities in autopsy-confirmed frontotemporal lobar degeneration and Alzheimer’s disease. Archives of Neurology, 69(4), 509–517. https://doi.org/10.1001/archneurol.2011.1021
   PubMedGoogle Scholar
• Braak, H., & Braak, E. (1991). Neuropathological staging of Alzheimer-related changes. Acta Neuropathologica, 82(4), 239–259. https://doi.org/10.1007/BF00308809
   PubMed Web of Science ®Google Scholar
• Bylsma, F. W., Rasmusson, D. X., Rebok, G. W., Keyl, P. M., Tune, L., & Brandt, J. (1995). Changes in visual fixation and saccadic eye movements in Alzheimer’s disease. International Journal of Psychophysiology, 19(1), 33–40. https://doi.org/10.1016/0167-8760(94)00060-r
   PubMed Web of Science ®Google Scholar
• Cangöz, B., Karakoç, E., & Selekler, K. (2007). Standardization study of the trail making test for Turkish adults and elderly people (ages 50 and over). Turkish Journal of Geriatrics, 10(2), 73–82.
   Google Scholar
• Chehrehnegar, N., Nejati, V., Shati, M., Esmaelli, M., Rezvani, Z., Haghi, M., & Foroughan, M. (2019). Behavioural and cognitive markers of mild cognitive impairment: Diagnostic value of saccadic eye movements and Simon task. Aging Clinical and Experimental Research, 31(11), 1591–1600. https://doi.org/10.1007/s40520-019-01121-w
   PubMed Web of Science ®Google Scholar
• Chern, A., & Golub, J. S. (2019). Age-related hearing loss and dementia. Alzheimer Disease & Associated Disorders, 33(3), 285–290. https://doi.org/10.1097/WAD.0000000000000325
   PubMed Web of Science ®Google Scholar
• Chetelat, G., Villemagne, V. L., Bourgeat, P., Pike, K. E., Jones, G., Ames, D., Ellis, K. A., Szoeke, C., Martins, R. N., O’Keefe, G. J., Salvado, O., Masters, C. L., Rowe, C. C., Biomarkers, A. I., & Group, L. R. (2010). Relationship between atrophy and beta-amyloid deposition in Alzheimer’s disease. Annals of Neurology, 67(3), 317–324. https://doi.org/10.1002/ana.21955
   PubMed Web of Science ®Google Scholar
• Clark, K., Squire, R. F., Merrikhi, Y., & Noudoost, B. (2015). Visual attention: Linking prefrontal sources to neuronal and behavioural correlates. Progress in Neurobiology, 132, 59–80. https://doi.org/10.1016/j.pneurobio.2015.06.006
   PubMed Web of Science ®Google Scholar
• Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.) ed.). Erlbaum.
   Google Scholar
• Corbetta, M., Kincade, J. M., Ollinger, J. M., McAvoy, M. P., & Shulman, G. L. (2000). Voluntary orienting is dissociated from target detection in human posterior parietal cortex. Nature Neuroscience, 3(3), 292–297. https://doi.org/10.1038/73009
   PubMed Web of Science ®Google Scholar
• Corwin, J. and Bylsma, F. W., (1993). Translated The Clinical Neuropsychologist, 7(1), 3–21. https://doi.org/10.1080/13854049308401883
   Web of Science ®Google Scholar
• Crawford, T. J., Higham, S., Mayes, J., Dale, M., Shaunak, S., & Lekwuwa, G. (2013). The role of working memory and attentional disengagement on inhibitory control: Effects of aging and Alzheimer’s disease. Age, 35(5), 1637–1650. https://doi.org/10.1007/s11357-012-9466-y
   PubMed Web of Science ®Google Scholar
• Crawford, T. J., Higham, S., Renvoize, T., Patel, J., Dale, M., Suriya, A., & Tetley, S. (2005). Inhibitory control of saccadic eye movements and cognitive impairment in Alzheimer’s disease. Biological Psychiatry, 57(9), 1052–1060. https://doi.org/10.1016/j.biopsych.2005.01.017
   PubMed Web of Science ®Google Scholar
• Crossland, M. (2010). Acuity. Encyclopedia of the Eye, 27–32. Philadelphia: Elsevier. https://doi.org/10.1016/B978-0-12-374203-2.00234-7
   Google Scholar
• Daffner, K. R., Scinto, L. F. M., Weintraub, S., Guinessey, B. S., & Mesulam, M. M. (1992). Diminished curiosity in patients with probable Alzheimer’s disease as measured by exploratory eye movements. Neurology, 42(2), 320–328. https://doi.org/10.1212/wnl.42.2.320
   PubMed Web of Science ®Google Scholar
• Domagalik, A., Beldzik, E., Fafrowicz, M., Oginska, H., & Marek, T. (2012). Neural networks related to pro-saccades and anti-saccades were revealed by independent component analysis. NeuroImage, 62(3), 1325–1333. https://doi.org/10.1016/j.neuroimage.2012.06.006
   PubMed Web of Science ®Google Scholar
• Dorris, M. C., & Munoz, D. P. (1995). A neural correlate for the gap effect on saccadic reaction times in monkey. Journal of Neurophysiology, 73(6), 2558–2562. https://doi.org/10.1152/jn.1995.73.6.2558
   PubMed Web of Science ®Google Scholar
• Dorris, M. C., & Munoz, D. P. (1998). Saccadic probability influences motor preparation signals and time to saccadic initiation. Journal of Neuroscience, 18(17), 7015–7026. https://doi.org/10.1523/JNEUROSCI.18-17-07015.1998
   PubMed Web of Science ®Google Scholar
• Dubois, B., Feldman, H. H., Jacova, C., Cummings, J. L., Dekosky, S. T., Barberger-Gateau, P., Delacourte, A., Frisoni, G., Fox, N. C., Galasko, D., Gauthier, S., Hampel, H., Jicha, G. A., Meguro, K., O’Brien, J., Pasquier, F., Robert, P., Rossor, M., Salloway, S., Scheltens, P. (2010). Revising the definition of Alzheimer’s disease: A new lexicon. The Lancet Neurology, 9(11), 1118–1127. 70223-4. https://doi.org/10.1016/S1474-4422(10)
   PubMed Web of Science ®Google Scholar
• Ertan, T., Eker, E., & Şar, V. (1997). Validity and reliability of geriatric depression scale in Turkish elderly population. Archives of Turkish Neuropsychiatry, 34(2), 62–71.
   Google Scholar
• Fan, J., McCandliss, B. D., Fossella, J., Flombaum, J. I., & Posner, M. I. (2005). The activation of attentional networks. Neuroimage, 26(2), 471–479. https://doi.org/10.1016/j.neuroimage.2005.02.004
   PubMed Web of Science ®Google Scholar
• Fleming, K. C., Adams, A. C., & Petersen, R. C. (1995). Dementia: Diagnosis and evaluation. Mayo Clinic Proceedings, 70(11), 1093–1107. https://doi.org/10.4065/70.11.1093
   PubMed Web of Science ®Google Scholar
• Fletcher, W. A., & Sharpe, J. A. (1986). Saccadic eye movement dysfunction in Alzheimer’s disease. Annals of Neurology, 20(4), 464–471. https://doi.org/10.1002/ana.410200405
   PubMed Web of Science ®Google Scholar
• Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). “Mini mental state.” A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12(3), 189–198. https://doi.org/10.1016/0022-3956(75)
   PubMed Web of Science ®Google Scholar
• Garbutt, S., Matlin, A., Hellmuth, J., Schenk, A. K., Johnson, J. K., Rosen, H., Dean, D., Kramer, J., Neuhaus, J., Miller, B. L., Lisberger, S. G., & Boxer, A. L. (2008). Oculomotor function in frontotemporal lobar degeneration, related disorders, and Alzheimer’s disease. Brain, 131(5), 1268–1281. https://doi.org/10.1093/brain/awn047
   PubMedGoogle Scholar
• Gates, G. A., & Mills, J. H. (2005). Presbycusis. The Lancet, 366(9491), 1111–1120. https://doi.org/10.1016/S0140-6736(05)67423-5
   PubMed Web of Science ®Google Scholar
• Gürvit, H., & Baran, B. (2007). Scales in dementias and cognitive disorders. Turkish Neuropsychiatry Archive, 44, 58–65.
   Google Scholar
• Hampel, H., Bürger, K., Teipel, S. J., Bokde, A. L. W., Zetterberg, H., & Blennow, K. (2008). Core candidate neurochemical, and imaging biomarkers of Alzheimer’s disease. Alzheimer’s & Dementia, 4(1), 38–48. https://doi.org/10.1016/j.jalz.2007.08.006
   PubMed Web of Science ®Google Scholar
• Hannula, D. E., Althoff, R. R., Warren, D. E., Riggs, L., Cohen, N. J., & Ryan, J. D. (2010). Worth a glance: Using eye movements to investigate the cognitive neuroscience of memory. Frontiers in Human Neuroscience, 4, 166. https://doi.org/10.3389/fnhum.2010.00166
   PubMed Web of Science ®Google Scholar
• Harris, C. M., & Wolpert, D. M. (2006). The main sequence of saccades optimizes speed-accuracy trade-off. Biological Cybernetics, 95(1), 21–29. https://doi.org/10.1007/s00422-006-0064-x
   PubMed Web of Science ®Google Scholar
• Heaton, R. K. (1981). Wisconsin card sorting test manual. Psychological Assessment Resources.
   Google Scholar
• Herse, P. R., & Bedell, H. E. (1989). Contrast sensitivity for letter and gratings targets under various stimulus conditions. Optometry and Vision Science, 66(11), 774–781. https://doi.org/10.1097/00006324-198911000-00009
   PubMed Web of Science ®Google Scholar
• Hershey, L. A., Whicker, L., Abel, L. A., Dell’Osso, L. F., Traccis, S., & Grossniklaus, D. (1983). Saccadic latency measures in dementia. Archives of Neurology, 40(9), 592–593. https://doi.org/10.1001/archneur.1983.04050080092023
   PubMedGoogle Scholar
• Heuer, H. W., Mirsky, J. B., Kong, E. L., Dickerson, B. C., Miller, B. L., Kramer, J. H., & Boxer, A. L. (2013). Antisaccade task reflects cortical involvement in mild cognitive impairment. Neurology, 81(14), 1235–1243. https://doi.org/10.1212/WNL.0b013e3182a6cbfe
   PubMed Web of Science ®Google Scholar
• Hodgson, T. L. (2002). The location marker effect: Saccadic latency increases with target eccentricity. Experimental Brain Research, 145(4), 539–542. http://dx.doi.org/10.1007/s00221-002-1162-1
   PubMed Web of Science ®Google Scholar
• Holden, J. G., Cosnard, A., Laurens, B., Asselineau, J., Biotti, D., Cubizolle, S., Dupouy, S., Formaglio, M., Koric, L., Seassau, M., Tilikete, C., Vighetto, A., & Tison, F. (2018). Prodromal Alzheimer’s disease demonstrates increased errors at a simple and automated anti-saccade task. Journal of Alzheimer’s Disease, 65(4), 1209–1223. https://doi.org/10.3233/JAD-180082
   PubMed Web of Science ®Google Scholar
• Hotson, J. R., & Steinke, G. W. (1988). Vertical and horizontal saccades in aging and dementia: Failure to inhibit anticipatory saccades. Neuro-Ophthalmology, 8(5), 267–273. https://doi.org/10.1192/bjp.140.6.56 https://doi.org/10.3109/01658108808996053
   Web of Science ®Google Scholar
• Hughes, C., Berg, L., Danziger, W., Coben, L. A., & Martin, R. L. (1982). A new clinical scale for the staging of dementia. The British Journal of Psychiatry, 140(6), 566–572. https://doi.org/10.1192/bjp.140.6.566
   PubMed Web of Science ®Google Scholar
• Hutton, S. B. (2008). Cognitive control of saccadic eye movements. Brain and Cognition, 68(3), 327–340. https://doi.org/10.1016/j.bandc.2008.08.021
   PubMed Web of Science ®Google Scholar
• Jack, C. R. J., Lowe, V. J., Senjem, M. L., Weigand, S. D., Kemp, B. J., Shiung, M. M., Knopman, D. S., Boeve, B. F., Klunk, W. E., Mathis, C. A., & Petersen, R. C. (2008). 11C PiB and structural MRI provide complementary information in imaging of Alzheimer’s disease and amnestic mild cognitive impairment. Brain, 131(3), 665–680. https://doi.org/10.1093/brain/awm336
   PubMed Web of Science ®Google Scholar
• Jennings, J. M., Dagenbach, D., Engle, C. M., & Funke, L. J. (2007). Age-related changes and the attention network task: An examination of alerting, orienting, and executive function. Aging Neuropsychology and Cognition, 14(4), 353–369. https://doi.org/10.1080/13825580600788837
   PubMed Web of Science ®Google Scholar
• Kahana-Levy, N., Lavidor, M., & Vakil, E. (2018). Prosaccade and antisaccade paradigms in person with Alzheimer’s disease: A meta-analytic review. Neuropsychology Review, 28(1), 16–31. https://doi.org/10.1007/s11065-017-9362-4
   PubMed Web of Science ®Google Scholar
• Kalesnykas, R. P., & Hallett, P. E. (1987). The differentiation of visually guided and anticipatory saccades in gap and overlap paradigms. Experimental Brain Research, 68(1), 115–121. https://doi.org/10.1007/BF00255238
   PubMed Web of Science ®Google Scholar
• Kalesnykas, R. P., & Hallett, P. E. (1994). Retinal eccentricity and the latency of eye saccades. Vision Research, 34(4), 517–531. 90165-1. https://doi.org/10.1016/0042-6989(94)
   PubMed Web of Science ®Google Scholar
• Kaplan, E., Goodglass, H., Weintraub, S., Segal, O., & van Loon-Vernoorn, A. (2001). Boston naming test (Second edition) ed.). Lea & Febiger.
   Google Scholar
• Karakaş, S. (2006). Neuropsychological test battery handbook for cognitive potentials: Research and development studies for neuropsychological tests.
   Google Scholar
• Karakaş, S., Irak, M., & Kurt, M. (1999). Wisconsin card sorting test and stroop test TBAG form: Comparative analysis in terms of measured properties. Journal of Turkish Psychiatry, Psychology, Psychopharmacology, 7(3), 179–192.
   Google Scholar
• Kaufman, L. D., Pratt, J., Levine, B., & Black, S. E. (2010). Antisaccades: A probe into the dorsolateral prefrontal cortex in Alzheimer’s disease. A critical review. Journal of Alzheimer’s Disease, 19(3), 781–793. https://doi.org/10.3233/JAD-2010-1275
   PubMed Web of Science ®Google Scholar
• Kelley, B. J., & Petersen, R. C. (2007). Alzheimer’s disease and mild cognitive impairment. Neurologic Clinics, 25(3), 577–609. https://doi.org/10.1016/j.ncl.2007.03.008
   PubMed Web of Science ®Google Scholar
• Keskinkılıç, C. (2008). Standardization of Benton face recognition test in a Turkish normal adult population. Turkish Journal of Neurology, 14(3), 179–190.
   Google Scholar
• Keskinoglu, P., Ucku, R., Yener, G., Yaka, E., Kurt, P., & Tunca, Z. (2009). Reliability and validity of revised Turkish version of mini mental state examination (rMMSE-T) in community-dwelling educated and uneducated elderly. International Journal of Geriatric Psychiatry, 24(11), 1242–1250. https://doi.org/10.1002/gps.2252
   PubMed Web of Science ®Google Scholar
• Klein, C., & Ettinger, U. (2019). eds Eye movement research. An introduction to its scientific foundations and applications. Springer Press. https://doi.org/10.1007/978-3-030-20085-5
   Google Scholar
• Koçoğlu, K., Hodgson, T. L., Eraslan-Boz, H., & Akdal, G. (2021). Deficits in saccadic eye movements differ between subtypes of patients with mild cognitive impairment. Journal of Clinical and Experimental Neuropsychology, 43(2), 187–198. https://doi.org/10.1080/13803395.2021.1900077
   PubMed Web of Science ®Google Scholar
• Kowler, E. (1990). The role of visual and cognitive processes in the control of eye movements. In E. Kowler (Ed.), Eye movements and their role in visual and cognitive processes (pp. 1–70). Elsevier.
   Google Scholar
• Kurt, M., Can, H., & Karakaş, S. (2016). Research and development study for the Turkish version of the Boston naming test. [Turkish.] Yeni Symposium, 54, 6–14. https://doi.org/10.5455/NYS.2016001
   Google Scholar
• Leigh, J. R., & Zee, D. S. (2015). The neurology of eye movements (5th ed.) ed.). Oxford University Press. https://doi.org/10.1093/med/9780199969289.001.0001
   Google Scholar
• Lenoble, Q., Bubbico, G., Szaffarczyk, S., Pasquier, F., & Boucart, M. (2015). Scene categorization in Alzheimer's disease: a saccadic choice task. Dementıa Geriatrıc Cognıtıve Disorders Extra, 5(1), 1–12. https://doi.org/10.1159/000366054
   PubMedGoogle Scholar
• Ludvigh, E. (1941). Extrafoveal visual acuity as measured with Snellen test-letters. American Journal of Ophthalmology, 24(3), 303–310. 90648-7. https://doi.org/10.1016/S0002-9394(41)
   Google Scholar
• Martin, A., Wiggs, C. L., Lalonde, F., & Mack, C. (1994). Word retrieval to letter and semantic cues: A double dissociation in normal subjects using interference tasks. Neuropsychologia, 32(12), 1487–1494. 90120-1. https://doi.org/10.1016/0028-3932(94)
   PubMed Web of Science ®Google Scholar
• McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, J. C., Kawas, R., Klunk, C. H., Koroshetz, W. E., Manly, W. J., Mayeux, J. J., Mohs, R., Morris, R. C., Rossor, J. C., Scheltens, M. N., Carrillo, P., Thies, M. C., Weintraub, B., & Phelps, C. H. (2011). The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging–Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimer’s & Dementia, 7(3), 263–269. https://doi.org/10.1016/j.jalz.2011.03.005
   PubMed Web of Science ®Google Scholar
• Meltzer, C. C., Zubieta, J. K., Brandt, J., Tune, L. E., Mayberg, H. S., & Frost, J. J. (1996). Regional hypometabolism in Alzheimer’s disease as measured by positron emission tomography after correction for effects of partial volume averaging. Neurology, 47(2), 454–461. https://doi.org/10.1212/wnl.47.2.454
   PubMed Web of Science ®Google Scholar
• Meyers, J. E., & Meyers, K. R. (1995). Rey complex figure test and recognition trial: Professional Manual. Psychological Assessment Resources.
   Google Scholar
• Molitor, R. J., Ko, P. C., & Ally, B. A. (2015). Eye movements in Alzheimer’s disease. Journal of Alzheimer’s Disease, 44(1), 1–12. https://doi.org/10.3233/JAD-141173
   PubMed Web of Science ®Google Scholar
• Morris, J. C., Heyman, A., Mohs, R. C., Hughes, J. P., Vam Belle, G., Fillenbaum, G., Mellits, E. D., & Clark, C. (1989). The consortium to establish a registry for Alzheimer’s Disease (CERAD). Part 1: Clinical and neuropsychological assessment of Alzheimer’s disease. Neurology, 39(9), 1159–1165. https://doi.org/10.1212/wnl.39.9.1159
   PubMed Web of Science ®Google Scholar
• Moser, A., Kömpf, D., & Olschinka, J. (1995). Eye movement dysfunction in dementia of the Alzheimer type. Dementia (Basel, Switzerland), 6(5), 264–268. https://doi.org/10.1159/000106957
   PubMedGoogle Scholar
• Mosimann, U. P., Mather, G., Wesnes, K. A., O’Brien, J. T., Burn, D. J., & McKeith, I. G. (2004). Visual perception in Parkinson disease dementia and dementia with Lewy bodies. Neurology, 63(11), 2091–2096. https://doi.org/10.1212/01.wnl.0000145764.70698.4e
   PubMed Web of Science ®Google Scholar
• Noiret, N., Carvalho, N., Laurent, É., Chopard, G., Binetruy, M., Nicolier, M., Monnin, J., Magnin, E., & Vandel, P. (2018). Saccadic eye movements and attentional control in Alzheimer’s disease. Archives of Clinical Neuropsychology, 33(1), 1–13. https://doi.org/10.1093/arclin/acx044
   PubMed Web of Science ®Google Scholar
• Oakley, M. T., & Eason, R. G. (1990). The conjoint influence of spatial selective attention and motor set on very short latency VERs. Neuropsychologia, 28(5), 487–497. 90074-X. https://doi.org/10.1016/0028-3932(90)
   PubMed Web of Science ®Google Scholar
• Öktem, Ö. (1992). Öktem Verbal Memory Processes Test (OVMPT)- A preliminary study. Turkish Neuropsychiatry Archive, 29(4), 196–206.
   Google Scholar
• Opwonya, J., Doan, D. N. T., Kim, S. G., Kim, J. I., Ku, B., Kim, S., Park, S., & Kim, J. U. (2022). saccadic eye movement in mild cognitive impairment and Alzheimer’s disease: A systematic review and meta-analysis. Neuropsychology Reviews, 32(2), 193–227. https://doi.org/10.1007/s11065-021-09495-3
   PubMed Web of Science ®Google Scholar
• Ossterrieth, P. A. (1944). Le test de copie d’une figure complex: Contribution a l’étude de la perception et de la mémoire [Test of copying a complex figure; contribution to the study of perception and memory]. Archives de Psychologie, 30, 286–356.
   Google Scholar
• Parasuraman, R., Greenwood, P. M., Haxby, J. V., & Grady, C. L. (1992). Visuospatial attention in dementia of the Alzheimer type. Brain, 115(3), 711–733. https://doi.org/10.1093/brain/115.3.711
   PubMed Web of Science ®Google Scholar
• Peltsch, A., Hemraj, A., Garcia, A., & Munoz, D. P. (2014). Saccade deficits in amnestic mild cognitive impairment resemble mild Alzheimer’s disease. European Journal of Neuroscience, 39(11), 2000–2013. https://doi.org/10.1111/ejn.12617
   PubMed Web of Science ®Google Scholar
• Pereira, M. L., Camargo, M., Aprahamian, I., & Forlenza, O. V. (2014). Eye movement analysis and cognitive processing: Detecting indicators of conversion to Alzheimer’s disease. Neuropsychiatric Disease and Treatment, 10, 1273–1285. https://doi.org/10.2147/NDT.S55371
   PubMed Web of Science ®Google Scholar
• Perry, R. J., & Hodges, J. R. (1999). Attention and executive deficits in Alzheimer's disease. A critical review. Brain : A Journal of Neurology, 122(3), 383–404. https://doi.org/10.1093/brain/122.3.383
   PubMed Web of Science ®Google Scholar
• Petersen, R. C. (2016). Mild Cognitive Impairment. Continuum (Minneapolis, Minn.), 22(2), 404–418. https://doi.org/10.1212/CON.0000000000000313
   PubMedGoogle Scholar
• Petersen, R. C., Roberts, R. O., Knopman, D. S., Boeve, B. F., Geda, Y. E., Ivnik, R. J., Smith, G. E., & Jack, C. R. (2009). Mild cognitive impairment: Ten years later. Archives of Neurology, 66(12), 1447–1455. https://doi.org/10.1001/archneurol.2009.266
   PubMed Web of Science ®Google Scholar
• Petersen, R. C., Smith, G. E., Waring, S. C., Ivnik, R. J., Tangalos, E. G., & Kokmen, E. (1999). Mild cognitive impairment: Clinical characterization and outcome. Archives of Neurology, 56(3), 303–308. https://doi.org/10.1001/archneur.56.3.303
   PubMed Web of Science ®Google Scholar
• Pierrot-Deseilligny, C., Milea, D., & Müri, R. M. (2004). Eye movement control by the cerebral cortex. Current Opinion in Neurology, 17(1), 17–25. https://doi.org/10.1097/00019052-200402000-00005
   PubMed Web of Science ®Google Scholar
• Pierrot-Deseilligny, C., Rivaud, S., Gaymard, B., Müri, R., & Vermersch, A. I. (1995). Cortical control of saccades. Annals of Neurology, 37(5), 557–567. https://doi.org/10.1002/ana.410370504
   PubMed Web of Science ®Google Scholar
• Pirozzolo, F. J., & Hansch, E. C. (1981). Oculomotor reaction time in dementia reflects degree of cerebral dysfunction. Science, 214(4518), 349–351. https://doi.org/10.1126/science.7280699
   PubMed Web of Science ®Google Scholar
• Polden, M., Wilcockson, T. D. W., & Crawford, T. J. (2020). The disengagement of visual attention: An eye-tracking study of cognitive impairment, ethnicity and age. Brain Sciences, 10(7), 461. https://doi.org/10.3390/brainsci10070461
   PubMed Web of Science ®Google Scholar
• Pouget, P. (2015). The cortex is in overall control of ‘voluntary’ eye movement. Eye (London, England), 29(2), 241–245. https://doi.org/10.1038/eye.2014.284
   PubMed Web of Science ®Google Scholar
• Reitan, R. M. (1958). Validity of the trail making test as an indicator of organic brain damage. Perceptual and Motor Skills, 8(3), 271–276. https://doi.org/10.2466/pms.1958.8.3.271-276
   Google Scholar
• Rey, A. (1941). L’examen psychologique dans les cas d’encephalopathie traumatique. Archives de Psychologie, 28, 286–340.
   Google Scholar
• Rouleau, I., Salmon, D. P., Butters, N., Kennedy, C., & McGuire, K. (1992). Quantitative and qualitative analyses of clock face drawings in Alzheimer’s and Huntington’s diseases. Brain and Cognition, 18(1), 70–87. https://doi.org/10.1016/0278-2626(92)90112-y
   PubMed Web of Science ®Google Scholar
• Sanford, A. M. (2017). Mild Cognitive Impairment. Clinics in Geriatric Medicine, 33(3), 325–337. https://doi.org/10.1016/j.cger.2017.02.005
   PubMed Web of Science ®Google Scholar
• Saslow, M. G. (1967). Latency for saccadic eye movement. Journal of the Optical Society of America, 57(8), 1030–1033. https://doi.org/10.1364/JOSA.57.001030
   PubMed Web of Science ®Google Scholar
• Scinto, L. F. M., Daffner, K. R., Castro, L., Weintraub, S., Vavrik, M., & Mesulam, M. M. (1994). Impairment of spatially directed attention in patients with probable Alzheimer’s disease as measured by eye movements. Archives of Neurology, 51(7), 682–688. https://doi.org/10.1001/archneur.1994.00540190062016
   PubMedGoogle Scholar
• Shafiq-Antonacci, R., Maruff, P., Masters, C., & Currie, J. (2003). Spectrum of saccade system function in Alzheimer disease. Archives of Neurology, 60(9), 1272–1278. https://doi.org/10.1001/archneur.60.9.1272
   PubMedGoogle Scholar
• Smith, E. E., & Kosslyn, S. M. (2007). Cognitive psychology: Mind and brain. Pearson/Prentice Hall.
   Google Scholar
• Smit, A. C., & Van Gisbergen, J. A. M. (1989). A short-latency transition in saccade dynamics during square-wave tracking and its significance for the differentiation of visually-guided and predictive saccades. Experimental Brain Research, 76(1), 64–74. https://doi.org/10.1007/BF00253624
   PubMed Web of Science ®Google Scholar
• Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., Iwatsubo, T., Jack, J. C. R., Kaye, J., Montine, T. J., Park, D. C., Reimani, E. M., Rowe, C. C., Siemers, E., Stern, Y., Yaffe, K., Carrillo, M. C., Thies, B., Morrison-Bogoard, M W., & Phelps, C. H. (2011). Towards defining the preclinical stage of Alzheimer’s disease: Recommendations from the national institute on aging Alzheimer’s association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimer’s & Dementia, 7(3), 280–292. https://doi.org/10.1016/j.jalz.2011.03.003
   PubMed Web of Science ®Google Scholar
• Stroop, J. R. (1935). Studies of interference in serial verbal reaction. Journal of Experimental Psychology, 18(6), 643–662. https://doi.org/10.1037/h0054651
   Google Scholar
• Tales, A., & Porter, G. (2008). Visual attention-related processing in Alzheimer’s disease. Reviews in Clinical Gerontology, 18(3), 229–243. https://doi.org/10.1017/S0959259809002792
   Google Scholar
• Taljaard, D. S., Olaithe, M., Brennan-Jones, C. G., Eikelboom, R. H., & Bucks, R. S. (2016). The relationship between hearing impairment and cognitive function: A meta-analysis in adults. Clinical Otolaryngology, 41(6), 718–729. https://doi.org/10.1111/coa.12607
   PubMed Web of Science ®Google Scholar
• Tumaç, A. (1997). The effect of age and education on performance in some tests sensitive to frontal injury in normal subjects [Unpublished master’s thesis]. Istanbul University, Institute of Social Sciences.
   Google Scholar
• Varan, E., Tanör, Ö. Ö., & Gürvit, H. (2007). Rey Complex Figure Test and Recognition practice (RKFT-T): Norm determination study on an adult Turkish sample. Turkish Journal of Neurology, 13, 387–394.
   Google Scholar
• Wechsler, D. (1987). WMS-R: Wechsler Memory Scale-Revised. The Psychological Corporation.
   Google Scholar
• Wilcockson, T. D. W., Mardanbegi, D., Xia, B., Taylor, S., Sawyer, P., Gellersen, H. W., Leroi, I., Killick, R., & Crawford, T. J. (2019). Abnormalities of saccadic eye movements in dementia due to Alzheimer’s disease and mild cognitive impairment. Aging, 11(15), 5389–5398. https://doi.org/10.18632/aging.102118
   PubMedGoogle Scholar
• Wyman, D., & Steinman, R. M. (1973). Latency characteristics of small saccades. Vision Research, 13(11), 2173–2175. https://doi.org/10.1016/0042-6989(73)90195-8
   PubMed Web of Science ®Google Scholar
• Yang, Q., Wang, T., Su, N., Liu, Y., Xiao, S., & Kapoula, Z. (2011). Long latency and high variability in accuracy-speed of prosaccades in Alzheimer’s disease at mild to moderate stage. Dementia and Geriatric Cognitive Disorders Extra, 1(1), 318–329. https://doi.org/10.1159/000333080
   PubMedGoogle Scholar
• Yang, Q., Wang, T., Su, N., Xiao, S., & Kapoula, Z. (2013). Specific saccade deficits in patients with Alzheimer’s disease at mild to moderate stage and in patients with amnestic mild cognitive impairment. Age, 35(4), 1287–1298. https://doi.org/10.1007/s11357-012-9420-z
   PubMedGoogle Scholar
• Yesavage, J. A., Brink, T. L., Rose, T. L., Lum, O., Huang, V., Adey, M., & Leirer, V. O. (1982). Development and validation of a geriatric depression screening scale: A preliminary report. Journal of Psychiatric Research, 17(1), 37–49. 90033-4. https://doi.org/10.1016/0022-3956(82)
   PubMed Web of Science ®Google Scholar