Publication Cover
Archives of Physiology and Biochemistry
The Journal of Metabolic Diseases
Volume 112, 2006 - Issue 1
143
Views
7
CrossRef citations to date
0
Altmetric
Research Article

Differential phosphorylation of IRS-1 and IRS-2 by insulin and IGF-I receptors

, , , &
Pages 37-47 | Received 21 Sep 2005, Accepted 13 Oct 2005, Published online: 10 Oct 2008

References

  • Amoui M, Craddock B P, Miller W T. Differential phosphorylation of IRS-1 by insulin and insulin-like growth factor I receptors in Chinese hamster ovary cells. J Endocrinol 2001; 171: 153–162
  • Bailyes E M, Nave B T, Soos M A, Orr S R, Hayward A C, Siddle K. Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting. Biochem J 1997; 327: 209–215
  • Baudry A, Lamothe B, Bucchini D, Jami J, Montarras D, Pinset C, Joshi R L. IGF-1 receptor as an alternative receptor for metabolic signaling in insulin receptor-deficient muscle cells. FEBS Lett 2001; 488: 174–178
  • Beguinot F, Kahn C R, Moses A C, Smith R J. Distinct biologically active receptors for insulin, insulin-like growth factor I, and insulin-like growth factor II in cultured skeletal muscle cells. J Biol Chem 1985; 260: 15892–15898
  • Bornfeldt K E, Gidlof R A, Wasteson A, Lake M, Skottner A, Arnqvist H J. Binding and biological effects of insulin, insulin analogs and insulin-like growth factors in rat aortic smooth muscle cells. Comparison of maximal growth promoting activities. Diabetologia 1991; 34: 307–313
  • Brunetti A, Maddux B A, Wong K Y, Goldfine I D. Muscle cell differentiation is associated with increased insulin receptor biosynthesis and messenger RNA levels. J Clin Invest 1989; 83: 192–198
  • Cheng Z Q, Adi S, Wu N Y, Hsiao D, Woo E J, Filvaroff E H, Gustafson T A, Rosenthal S M. Functional inactivation of the IGF-I receptor delays differentiation of skeletal muscle cells. J Endocrinol 2000; 167: 175–182
  • Crown A L, He X L, Holly J M, Lightman S L, Stewart C E. Characterisation of the IGF system in a primary adult human skeletal muscle cell model, and comparison of the effects of insulin and IGF-I on protein metabolism. J Endocrinol 2000; 167: 403–415
  • De Meyts P, Wallach B, Christoffersen C T, Urso B, Gronskov K, Latus L J, Yakushiji F, Ilondo M M, Shymko R M. The insulin-like growth factor-I receptor. Structure, ligand-binding mechanism and signal transduction. Horm Res 1994; 42: 152–169
  • De Meyts P, Christoffersen C T, Urso B, Wallach B, Gronskov K, Yakushiji F, Shymko R M. Role of the time factor in signaling specificity: application to mitogenic and metabolic signaling by the insulin and insulin-like growth factor-I receptor tyrosine kinases. Metabolism 1995; 44(Suppl 4)2–11
  • Dietze D, Koenen M, Rohrig K, Horikoshi H, Hauner H, Eckel J. Impairment of insulin signaling in human skeletal muscle cells by co-culture with human adipocytes. Diabetes 2002; 51: 2369–2376
  • Drejer K, Kruse V, Larsen U D, Hougaard P, Bjorn S, Gammeltoft S. Receptor binding and tyrosine kinase activation by insulin analogues with extreme affinities studied in human hepatoma HepG2 cells. Diabetes 1991; 40: 1488–1495
  • Fasshauer M, Klein J, Ueki K, Kriauciunas K M, Benito M, White M F, Kahn C R. Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes. J Biol Chem 2000; 275: 25494–25501
  • Fasshauer M, Klein J, Kriauciunas K M, Ueki K, Benito M, Kahn C R. Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes. Mol Cell Biol 2001; 21: 319–329
  • Federici M, Porzio O, Zucaro L, Fusco A, Borboni P, Lauro D, Sesti G. Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues. Mol Cell Endocrinol 1997; 129: 121–126
  • Fernandez A M, Dupont J, Farrar R P, Lee S, Stannard B, Le Roith D. Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscle. J Clin Invest 2002; 109: 347–355
  • He W, Craparo A, Zhu Y, O'Neill T J, Wang L M, Pierce J H, Gustafson T A. Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2. J Biol Chem 1996; 271: 11641–11645
  • Jetton T L, Liu Y Q, Trotman W E, Nevin P W, Sun X J, Leahy J L. Enhanced expression of insulin receptor substrate-2 and activation of protein kinase B/Akt in regenerating pancreatic duct epithelium of 60%-partial pancreatectomy rats. Diabetologia 2001; 44: 2056–2065
  • Kasuya J, Paz I B, Maddux B A, Goldfine I D, Hefta S A, Fujita-Yamaguchi Y. Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification. Biochemistry 1993; 32: 13531–13536
  • Kurtzhals P, Schaffer L, Sorensen A, Kristensen C, Jonassen I, Schmid C, Trub T. Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use. Diabetes 2000; 49: 999–1005
  • Lamothe B, Baudry A, Christoffersen C T, De Meyts P, Jami J, Bucchini D, Joshi R L. Insulin receptor-deficient cells as a new tool for dissecting complex interplay in insulin and insulin-like growth factors. FEBS Lett 1998; 426: 381–385
  • Miele C, Caruso M, Calleja V, Auricchio R, Oriente F, Formisano P, Condorelli G, Cafieri A, Sawka-Verhelle D, Van Obberghen E, Beguinot F. Differential role of insulin receptor substrate (IRS)-1 and IRS-2 in L6 skeletal muscle cells expressing the Arg1152 → Gln insulin receptor. J Biol Chem 1999; 274: 3094–3102
  • Milazzo G, Sciacca L, Papa V, Goldfine I D, Vigneri R. ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: evidence for enhanced interactions with the insulin-like growth factor-I receptor. Mol Carcinog 1997; 18: 19–25
  • Nakae J, Kido Y, Accili D. Distinct and overlapping functions of insulin and IGF-I receptors. Endocr Rev 2001; 22: 818–835
  • Pandini G, Frasca F, Mineo R, Sciacca L, Vigneti R, Belfiore A. Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved. J Biol Chem 2002; 277: 39684–39695
  • Pederson T, Rondinone C M. Regulation of proteins involved in insulin signaling pathways in differentiating human adipocytes. Biochem Biophys Res Commun 2000; 276: 162–168
  • Rakatzi I, Ramrath S, Ledwig D, Dransfeld O, Bartels T, Seipke G, Eckel J. A novel insulin analog with unique properties: LysB3,GluB29 insulin induces prominent activation of IRS-2 but marginal phosphorylation of IRS-1. Diabetes 2003; 52: 2227–2238
  • Rosenthal S M, Brunetti A, Brown E J, Mamula P W, Goldfine I D. Regulation of insulin-like growth factor (IGF) I receptor expression during muscle cell differentiation. Potential autocrine role of IGF-II. J Clin Invest 1991; 87: 1212–1219
  • Rother K I, Imai Y, Caruso M, Beguinot F, Formisano P, Accili D. Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes. J Biol Chem 1998; 273: 17491–17497
  • Sawka-Verhelle D, Baron V, Mothe I, Filloux C, White M F, Van Obberghen E. Tyr624 and Tyr628 in insulin receptor substrate-2 mediate its association with the insulin receptor. J Biol Chem 1997; 272: 16414–16420
  • Schacher D H, VanHoy R W, Liu Q, Arkins S, Dantzer R, Freund G G, Kelley K W. Developmental expression of insulin receptor substrate-2 during dimethylsulfoxide-induced differentiation of human HL-60 cells. J Immunol 2000; 164: 113–120
  • Shimizu M, Webster C, Morgan D O, Blau H M, Roth R A. Insulin and insulinlike growth factor receptors and responses in cultured human muscle cells. Am J Physiol 1986; 251: E611–E615
  • Shymko R M, Dumont E, De Meyts P, Dumont J E. Timing-dependence of insulin-receptor mitogenic versus metabolic signalling: a plausible model based on coincidence of hormone and effector binding. Biochem J 1999; 339: 675–683
  • Siddle K, Urso B, Niesler C A, Cope D L, Molina L, Surinya K H, Soos M A. Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors. Biochem Soc Trans 2001; 29: 513–525
  • Slieker L J, Brooke G S, DiMarchi R D, Flora D B, Green L K, Hoffmann J A, Long H B, Fan L, Shields J E, Sundell K L, Surface P L, Chance R E. Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor. Diabetologia 1997; 40(Suppl 2)54–61
  • Soos M A, Siddle K. Immunological relationships between receptors for insulin and insulin-like growth factor I. Evidence for structural heterogeneity of insulin-like growth factor I receptors involving hybrids with insulin receptors. Biochem J 1989; 263: 553–563
  • Soos M A, Siddle K, Baron M D, Heward J M, Luzio J P, Bellatin J, Lennox E S. Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor. Biochem J 1986; 235: 199–208
  • Soos M A, Field C E, Lammers R, Ullrich A, Zhang B, Roth R A, Andersen A S, Kjeldsen T, Siddle K. A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity. J Biol Chem 1992; 267: 12955–12963
  • Soos M A, Field C E, Siddle K. Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity. Biochem J 1993; 290: 419–426
  • Stewart C E, Rotwein P. Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors. Physiol Rev 1996; 76: 1005–1026
  • Virkamaki A, Ueki K, Kahn C R. Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance. J Clin Invest 1999; 103: 931–943
  • White M F. IRS proteins and the common path to diabetes. Am J Physiol Endocrinol Metab 2002; 283: E413–E422
  • Yarden Y, Ullrich A. Growth factor receptor tyrosine kinases. Annu Rev Biochem 1988; 57: 443–478

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.