Alteration of miR-21, miR-433 and miR-590 tissue expression related to the TGF-β signaling pathway in ulcerative colitis patients

References

• Biernacka, A., Dobaczewski, M., and Frangogiannis, N.G., 2011. TGF-β signaling in fibrosis. Growth Factors ( Factors), 29 (5), 196–202.
   PubMed Web of Science ®Google Scholar
• Catalanotto, C., Cogoni, C., and Zardo, G., 2016. MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions. International Journal of Molecular Sciences, 17 (10), 1712.
   PubMed Web of Science ®Google Scholar
• Collaborators, G.I.B.D., 2020. The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Gastroenterol Hepatol, 5, 17–30.
   PubMed Web of Science ®Google Scholar
• Dong, L., et al., 2014. Decreased expression of microRNA-21 correlates with the imbalance of Th17 and Treg cells in patients with rheumatoid arthritis. Journal of Cellular and Molecular Medicine, 18 (11), 2213–2224.
   PubMed Web of Science ®Google Scholar
• Fiocchi, C. and Lund, P.K., 2011. Themes in fibrosis and gastrointestinal inflammation. American Journal of Physiology-Gastrointestinal and Liver Physiology, 300 (5), G677–83.
   PubMed Web of Science ®Google Scholar
• Guo, L., et al., 2016. MicroRNAs, TGF-β signaling, and the inflammatory microenvironment in cancer. Tumor Biology, 37 (1), 115–125.
   PubMedGoogle Scholar
• Hinz, B., 2015. The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship. Matrix Biology, 47, 54–65.
   PubMed Web of Science ®Google Scholar
• Ihara, S., Hirata, Y., and Koike, K., 2017a. TGF-beta in inflammatory bowel disease: a key regulator of immune cells, epithelium, and the intestinal microbiota. Journal of Gastroenterology, 52 (7), 777–787.
   PubMed Web of Science ®Google Scholar
• Ihara, S., Hirata, Y., and Koike, K., 2017b. TGF-β in inflammatory bowel disease: a key regulator of immune cells, epithelium, and the intestinal microbiota. Journal of Gastroenterology, 52 (7), 777–787.
   PubMed Web of Science ®Google Scholar
• Jiang, X., et al., 2012. MicroRNA-590-5p regulates proliferation and invasion in human hepatocellular carcinoma cells by targeting TGF-β RII. Molecules and Cells, 33 (6), 545–551.
   PubMed Web of Science ®Google Scholar
• Kalla, R., et al., 2015. MicroRNAs: new players in IBD. Gut, 64 (3), 504–513.
   PubMed Web of Science ®Google Scholar
• Klass, B.R., Grobbelaar, A.O., and Rolfe, K.J., 2009. Transforming growth factor β1 signalling, wound healing and repair: a multifunctional cytokine with clinical implications for wound repair, a delicate balance. Postgraduate Medical Journal, 85 (999), 9–14.
   PubMed Web of Science ®Google Scholar
• Li, Q., et al., 2013a. MiR-21/Smad 7 signaling determines TGF-β1-induced CAF formation. Scientific Reports, 3 (1), 2038.
   PubMedGoogle Scholar
• Li, R., et al., 2013b. The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-beta/Smad3-Azin1 pathway. Kidney International, 84 (6), 1129–1144.,
   PubMed Web of Science ®Google Scholar
• Li, C. and Kuemmerle, J.F., 2014. Mechanisms that mediate the development of fibrosis in patients with Crohn’s disease. Inflammatory Bowel Diseases, 20 (7), 1250–1258.
   PubMed Web of Science ®Google Scholar
• Liu, Y., et al., 2017. YAP modulates TGF-β1-induced simultaneous apoptosis and EMT through upregulation of the EGF receptor. Scientific Reports, 7 (1), 45523.
   PubMedGoogle Scholar
• Lv, W., et al., 2018. Inflammation and renal fibrosis: Recent developments on key signaling molecules as potential therapeutic targets. European Journal of Pharmacology , 820, 65–76.
   PubMed Web of Science ®Google Scholar
• Matricon, J., Barnich, N., and Ardid, D., 2010. Immunopathogenesis of inflammatory bowel disease. Self/Nonself , 1 (4), 299–309.
   PubMedGoogle Scholar
• Ng, S.C., et al., 2018. Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies. The Lancet, 390 (10114), 2769–2778.
   PubMed Web of Science ®Google Scholar
• Palmieri, O., et al., 2017. Functional Implications of MicroRNAs in Crohn’s Disease Revealed by Integrating MicroRNA and Messenger RNA Expression Profiling. International Journal of Molecular Sciences, 18 (7), 1580.
   PubMed Web of Science ®Google Scholar
• Papageorgis, P., 2015. TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis. Journal of Oncology , 2015, 1–587193.
   Web of Science ®Google Scholar
• Peacock, O., et al., 2014. Inflammation and MiR-21 Pathways Functionally Interact to Downregulate PDCD4 in Colorectal Cancer. PLOS One, 9 (10), e110267.
   PubMed Web of Science ®Google Scholar
• Pekow, J.R. and Kwon, J.H., 2012. MicroRNAs in inflammatory bowel disease. Inflammatory Bowel Diseases, 18 (1), 187–193.
   PubMed Web of Science ®Google Scholar
• Sarlinova, M., et al., 2016. miR-21, miR-221 and miR-150 Are Deregulated in Peripheral Blood of Patients with Colorectal Cancer. Anticancer Research, 36 (10), 5449–5454.,
   PubMed Web of Science ®Google Scholar
• Scharl, M., et al., 2015. Hallmarks of epithelial to mesenchymal transition are detectable in Crohn’s disease associated intestinal fibrosis. Clinical and Translational Medicine, 4 (1), 1–1.,
   PubMedGoogle Scholar
• Schmittgen, T.D. and Livak, K.J., 2008. Analyzing real-time PCR data by the comparative C(T) method. Nature Protocols, 3 (6), 1101–1108.
   PubMed Web of Science ®Google Scholar
• Tahamtan, A., et al., 2018. Anti-Inflammatory MicroRNAs and Their Potential for Inflammatory Diseases Treatment. Frontiers in Immunology, 9, 1377–1377.
   PubMed Web of Science ®Google Scholar
• Tao, L., et al., 2016. Crucial Role of miR-433 in Regulating Cardiac Fibrosis. Theranostics, 6 (12), 2068–2083.,
   PubMed Web of Science ®Google Scholar
• Weisshof, R., et al., 2018. Emerging Therapies for Inflammatory Bowel Disease. Advances in Therapy, 35 (11), 1746–1762.,
   PubMed Web of Science ®Google Scholar
• Yang, J., Zhuang, Y. and Liu, J., 2019. Upregulation of microRNA-590 in rheumatoid arthritis promotes apoptosis of bone cells through transforming growth factor-β1/phosphoinositide 3-kinase/Akt signaling. International Journal of Molecular Medicine, 43, 2212–2220.
   PubMed Web of Science ®Google Scholar
• Zhang, M., et al., 2017. Interactions between Intestinal Microbiota and Host Immune Response in Inflammatory Bowel Disease. Frontiers in Immunology, 8, 942
   PubMed Web of Science ®Google Scholar
• Zhao, X., et al., 2020. Targeting metabolic dysregulation for fibrosis therapy. Nature Reviews Drug Discovery, 19 (1), 57–75.
   PubMed Web of Science ®Google Scholar
• Zhao, Y.-L., Zhu, R.-T., and Sun, Y.-L., 2016. Epithelial-mesenchymal transition in liver fibrosis. Biomedical Reports, 4 (3), 269–274.
   PubMed Web of Science ®Google Scholar
• Zhong, X., et al., 2011. Smad3-mediated upregulation of miR-21 promotes renal fibrosis. Journal of the American Society of Nephrology, 22 (9), 1668–1681.
   PubMed Web of Science ®Google Scholar