Developmental Basis of Nanophthalmos: MFRP Is Required for both Prenatal Ocular Growth and Postnatal Emmetropization

REFERENCES

• Warburg M. Genetics of microphthalmos. Intl. Ophthalmol 1981; 4: 45–65
   PubMed Web of Science ®Google Scholar
• Traboulsi E I. Colobomatous Microphthalmia, Anophthalmia and associated malformation syndromes. Genetic diseases of the eye, a textbook and atlas, E. Traboulsi. Oxford University Press, New York 1998
   Google Scholar
• Kallen B, Tornqvist K. The epidemiology of anophthalmia and microphthalmia in Sweden. Eur J Epidemiol 2005; 20: 345–350
   PubMed Web of Science ®Google Scholar
• Mann I. The development of the human eye. British Medical Association Press, London 1964
   Google Scholar
• Fitzpatrick D R, van Heyningen V. Developmental eye disorders. Curr Opin Genet Dev. 2005; 15: 348–353
   PubMed Web of Science ®Google Scholar
• Duke-Elder S. Pathological refractive errors. System of Ophthalmology. Vol. 3, S Duke-Elder. Mosby, St. Louis 1964
   Google Scholar
• Singh O S, Sofinski S J. Nanophthalmos: guidelines for diagnosis and therapy. Principles and Practice of Ophthalmology. Vol 3, D M Albert, F A Jakobiec. W.B. Saunders, Philadelphia 1995
   Google Scholar
• Ryan E, Zwaan J, Chylack L. Nanopthalmos with uveal effusion. Clinical and embryologic considerations. Ophthalmology 1982; 89: 1013–1017
   PubMed Web of Science ®Google Scholar
• Brockhurst R J. Vortex vein decompression for nanophthalmic uveal effusion. Arch Ophthalmol. 1980; 98: 1987–1990
   PubMedGoogle Scholar
• Sundin O H, Leppert G S, Silva E D, Yang J M, Dharmaraj S, Maumenee I H, Santos L C, Parsa C F, Traboulsi E I, Broman K W, Dibernardo C, Sunness J S, Toy J, Weinberg E M. Extreme hyperopia is the result of null mutations in MFRP, which encodes a frizzled-related protein. Proc Natl Acad Sci U S A. 2005; 102: 9553–9558
   PubMed Web of Science ®Google Scholar
• Katoh M. Molecular cloning and characterization of MFRP, a novel gene encoding a membrane-type frizzled-related protein. Biochem Biophys Res Commun. 2001; 282: 116–123
   PubMed Web of Science ®Google Scholar
• Mandal M N, Vasireddy V, Jablonski M M, Wang X, Heckenlively J R, Hughes B A, Reddy G B, Ayyagari R. Spatial and temporal expression of MFRP and its interaction with CTRP5. Invest Ophthalmol Vis Sci. 2006; 5514–5521
   Google Scholar
• Sundin O H. The mouse's eye and Mfrp: Not quite human. Ophthalmic Genet. 2005; 26: 153–155
   Google Scholar
• Hawes N L, Chang B, Hageman G S, Nusinowitz S, Nishina P M, Schneider B S, Smith R S, Roderick T H, Davisson M T, Heckenlively J R. Retinal degeneration 6 (rd6): A new mouse model for human retinitis punctata albescens. Invest Ophthalmol Vis Sci 2000; 41: 3149–3157
   Google Scholar
• Chang B, Hawes N L, Hurd R E, Wang J, Howell D, Davisson M T, Roderick T H, Nusinowitz S, Heckenlively J R. Mouse models of ocular diseases. Vis Neurosci. 2005; 22: 587–593
   PubMed Web of Science ®Google Scholar
• Hasegawa T, McLeod D S, Bhutto I A, Prow T, Merges C A, Grebe R, Lutty G A. The embryonic human choriocapillaris develops by hemo-vasculogenesis. Devel. Dynam. 2007; 236: 2089–2100
   Google Scholar
• Bhutto I A, Kim S Y, McLeod D S, Merges C, Fukai N, Olsen B R, Lutty G A. Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2004; 45: 1544–1552
   Google Scholar
• Lyhne N, Sjolie A K, Kyvik K O, Green A. The importance of genes and environment for ocular refraction and its determiners: a population based study among 20–45 year old twins. Br J Ophthalmol. 2001; 85: 1470–1476
   PubMed Web of Science ®Google Scholar
• Larsen J S. The sagittal growth of the eye IV. Ultrasonic measurement of the axial length of the eye from birth to puberty. Acta Ophthalmologica (Copenh) 1971; 49: 873–886
   Web of Science ®Google Scholar
• Fledelius H C, Christensen A C. Reappraisal of the human ocular growth curve in fetal life, infancy, and early childhood. Br J Ophthalmol 1996; 80: 918–921
   PubMed Web of Science ®Google Scholar
• Serrano J C, Hodgkins P R, Taylor D S, Gole G A, Kriss A. The nanophthalmic macula. Br J Ophthalmol. 1998; 82: 276–279
   PubMed Web of Science ®Google Scholar
• Walsh M K, Goldberg M F. Abnormal foveal avascular zone in nanophthalmos. Am J Ophthalmol. 2007; 143: 1067–1068
   PubMedGoogle Scholar
• Mutti D O, Mitchell G L, Jones L A, Friedman N E, Frane S L, Lin W K, Moeschberger M L, Zadnik K. Axial growth and changes in lenticular and corneal power during emmetropization in infants. Invest Ophthalmol Vis Sci. 2005; 46: 3074–3080
   PubMed Web of Science ®Google Scholar
• Mutti D O, Zadnik K, Fusaro R E, Friedman N E, Sholtz R I, Adams A J. Optical and structural development of the crystalline lens in childhood. Invest Ophthalmol Vis Sci. 1998; 39: 120–133
   PubMed Web of Science ®Google Scholar
• O'Brien K M, Schulte D, Hendrickson A E. Expression of photoreceptor-associated molecules during human fetal eye development. Mol Vis. 2003; 9: 401–409
   Google Scholar
• Hollyfield J G. Hyaluronan and the functional organization of the interphotoreceptor matrix. Invest Ophthalmol Vis Sci. 1999; 40: 2767–2769
   PubMedGoogle Scholar
• Rahner C, Fukuhara M, Peng S, Kojima S, Rizzolo L J. The apical and basal environments of the retinal pigment epithelium regulate the maturation of tight junctions during development. J Cell Sci. 2004; 117: 3307–3318
   Google Scholar
• Othman M I, Sullivan S A, Skuta G L, Crockrell D A, Stringham H M, Downs C A, Fornes A, Mick A, Boehnke M, Vollrath D, Richards J E. Autosomal dominant nanophthalmos (NNO1) with high hyperopia and angle-closure glaucoma maps to chromosome 11. Am. J. Hum. Genet. 1998; 63: 1411–1418
   PubMed Web of Science ®Google Scholar
• Conrad A H, Zhang Y, Walker A R, Olberding L A, Hanzlick A, Zimmer A J, Morffi R, Conrad G W. Thyroxine affects expression of KSPG-related genes, the carbonic anhydrase II gene, and KS sulfation in the embryonic chicken cornea. Invest Ophthalmol Vis Sci. 2006; 47: 120–132
   Google Scholar
• Sorsby A. Biology of the eye as an optical system. Duane's Clinical Ophthalmology. Vol. 1, W Tasman, E A Jaeger. Lippincott, Philadelphia 1993
   Google Scholar
• Wallman J, Winawer J. Homeostasis of eye growth and the question of myopia. Neuron 2004; 43: 447–468
   PubMed Web of Science ®Google Scholar
• Rymer J, Wildsoet C F. The role of the retinal pigment epithelium in eye growth regulation and myopia: A review. Vis Neurosci. 2005; 22: 251–261
   PubMed Web of Science ®Google Scholar