Vasorelaxant mode of action of dichloromethane-soluble extract from Agastache mexicana and its main bioactive compounds

References

• Aguirre-Crespo F, Vergara-Galicia J, Villalobos-Molina R, López-Guerrero JJ, Navarrete-Vázquez G, Estrada-Soto S. 2006. Ursolic acid mediates the vasorelaxant activity of Lepechinia caulescens via NO release in isolated rat thoracic aorta. Life Sci. 79:1062–1068.
   PubMed Web of Science ®Google Scholar
• Arredondo A, Zúñiga A. 2006. Epidemiologic changes and economic burden of hypertension in Latin America: evidence from Mexico. Am J Hypertens. 19:553–559.
   PubMed Web of Science ®Google Scholar
• Bei-Bei Z, Yuan D, Zhi-Xin L. 2011. Chemical constituents of Saussurea eopygmaea. Chin J Nat Med. 9:33–37.
   Google Scholar
• Brunton LL, Lazo JS, Parker KL. 2006. Goodman and Gilman’s. The pharmacological basis of therapeutics. 11th ed. New York: McGraw-Hill.
   Google Scholar
• Calderone V, Chericoni S, Martinelli C, Testai L, Nardi A, Morelli I, Breschi MC, Martinotti E. 2004. Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels. Naunyn Schmiedebergs Arch Pharmacol. 370:290–298.
   PubMed Web of Science ®Google Scholar
• Castillo-España P, Cisneros-Estrada A, Garduño-Ramírez ML, Hernández-Abreu O, Ramírez R, Estrada-Soto S. 2009. Preliminary ethnopharmacological survey of plants used in Mexico for the treatment of hypertension. Pharmacog Rev. 3:41–65.
   Google Scholar
• Estrada-Reyes R, Aguirre Hernández E, García-Argáez A, Soto Hernández M, Linares E, Bye R, Heinze G, Martínez-Vázquez M. 2004. Comparative chemical composition of Agastache mexicana subsp. mexicana and A. mexicana subsp. xolocotziana. Biochem Syst Ecol. 32:685–694.
   Web of Science ®Google Scholar
• Estrada-Reyes R, López-Rubalcava C, Ferreyra-Cruz OA, Dorantes-Barrón AM, Heinze G, Moreno Aguilar J, Martínez-Vázquez M. 2014. Central nervous system effects and chemical composition of two subspecies of Agastache mexicana; an ethnomedicine of Mexico. J Ethnopharmacol. 153:98–110.
   PubMed Web of Science ®Google Scholar
• Estrada-Soto S, Rivera-Leyva JC, Ramírez-Espinosa JJ, Castillo-España P, Aguirre-Crespo F, Hernández-Abreu O. 2010. Vasorelaxant effect of Valeriana edulis ssp. procera (Valerianaceae) and its mode of action as calcium channel blocker. J Pharm Pharmacol. 62:1167–1174.
   PubMed Web of Science ®Google Scholar
• González-Ramírez A, González-Trujano ME, Pellicer F, López-Muñoz FJ. 2012. Anti-nociceptive and anti-inflammatory activities of the Agastache mexicana extracts by using several experimental models in rodents. J Ethnopharmacol. 142:700–705.
   PubMed Web of Science ®Google Scholar
• González-Trujano ME, Ponce-Muñoz H, Hidalgo-Figueroa S, Navarrete-Vázquez G, Estrada-Soto S. 2015. Depressant effects of Agastache mexicana methanol extract and one of major metabolites tilianin. Asian Pac J Trop Med. 8:185–190.
   PubMed Web of Science ®Google Scholar
• González-Trujano ME, Ventura-Martínez R, Chávez M, Díaz-Reval I, Pellicer F. 2012. Spasmolytic and antinociceptive activities of ursolic acid and acacetin identified in Agastache mexicana. Planta Med. 78:793–796.
   PubMed Web of Science ®Google Scholar
• Hernández-Abreu O, Castillo-España P, León-Rivera I, Ibarra-Barajas M, Villalobos-Molina R, González-Christen J, Vergara-Galicia J, Estrada-Soto S. 2009. Antihypertensive and vasorelaxant effects of tilianin isolated from Agastache mexicana are mediated by NO/cGMP pathway and potassium channel opening. Biochem Pharmacol. 78:54–61.
   PubMed Web of Science ®Google Scholar
• Huang Y, Ho IH. 1996. Separate activation of intracellular Ca2+ release, voltage-dependent and receptor-operated Ca2+ channels in the rat aorta. Chin J Physiol. 39:1–8.
   PubMedGoogle Scholar
• Ibarra-Alvarado C, Rojas A, Mendoza S, Bah M, Gutiérrez DM, Hernández-Sandoval L, Martínez M. 2010. Vasoactive and antioxidant activities of plants used in Mexican traditional medicine for the treatment of cardiovascular diseases. Pharm Biol. 48:732–739.
   PubMed Web of Science ®Google Scholar
• Molina-Hernández M, Téllez-alcántara P, Martínez E. 2000. Agastache mexicana may produce anxiogenic-like actions in the male rat. Phytomedicine. 7:199–203.
   PubMed Web of Science ®Google Scholar
• Monroy-Ortiz C, Castillo-España P. 2007. Medicinal plants used in the State of Morelos. 2nd ed. Morelos, Mexico: Centro de Investigaciones Biológicas, Universidad Autónoma del Estado de Morelos.
   Google Scholar
• Rios MY, López-Martínez S, López-Vallejo F, Medina-Franco JL, Villalobos-Molina R, Ibarra-Barajas M, Navarrete-Vázquez G, Hidalgo-Figueroa S, Hernández-Abreu O, Estrada-Soto S. 2012. Vasorelaxant activity of some structurally-related triterpenic acids from Phoradendron reichenbachianum (Viscaceae) mainly by NO production: ex vivo and in silico studies. Fitoterapia. 83:1023–1029.
   PubMed Web of Science ®Google Scholar
• Rodriguez-Rodriguez R, Herrera MD, Perona JS, Ruiz-Gutiérrez V. 2004. Potential vasorelaxant effects of oleanolic acid and erythrodiol, two triterpenoids contained in ‘orujo’ olive oil, on rat aorta. Br J Nutr. 92:635–642.
   PubMed Web of Science ®Google Scholar
• Rubinstein A, Alcocer L, Chagas A. 2009. High blood pressure in Latin America: a call to action. Ther Adv Cardiovasc Dis. 3:259–285.
   PubMedGoogle Scholar
• Somova LO, Nadar A, Rammanan P, Shode FO. 2003. Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension. Phytomedicine. 10:115–121.
   PubMed Web of Science ®Google Scholar
• Steinhoff B. 2004. New documents for the assessment of herbal medicinal products. Phytomedicine. 11:467–468.
   Web of Science ®Google Scholar
• Topçu G, Yapar G, Türkmen Z, Gören AC, Öksüz S, Schilling JK, Kingston DGI. 2011. Ovarian antiproliferative activity directed isolation of triterpenoids from fruits of Eucalyptus camaldulensis Dehnh. Phytochem Lett. 4:421–425.
   Web of Science ®Google Scholar
• Verano J, González-Trujano ME, Déciga-Campos M, Ventura-Martínez R, Pellicer F. 2013. Ursolic acid from Agastache mexicana aerial parts produces antinociceptive activity involving TRPV1 receptors, cGMP and a serotonergic synergism. Pharmacol Biochem Behav. 110:255–264.
   PubMed Web of Science ®Google Scholar
• Vergara-Galicia J, Ortiz-Andrade R, Rivera-Leyva JC, Castillo-España P, Villalobos-Molina R, Ibarra-Barajas M, Gallardo-Ortiz I, Estrada-Soto S. 2010. Vasorelaxant and antihypertensive effects of methanolic extract from roots of Laelia anceps are mediated by calcium-channel antagonism. Fitoterapia. 81:350–357.
   PubMed Web of Science ®Google Scholar