In vivo anti-ulcerogenic effect of okra (Abelmoschus esculentus) on ethanol-induced acute gastric mucosal lesions

References

• Abourehab MAS, Khaled KA, Sarhan HAA. 2015. Evaluation of combined famotidine with quercetin for the treatment of peptic ulcer: in vivo animal study. Drug Des Devel Ther. 13:2159–2169.
   Google Scholar
• Amirshahrokhi K, Khalili AR. 2015. The effect of thalidomide on ethanol-induced gastric mucosal damage in mice: Involvement of inflammatory cytokines and nitric oxide. Chem Biol Interact. 225:63–69.
   PubMed Web of Science ®Google Scholar
• Arab HH, Salama SA, Omar HA. 2015. Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions. PLoS One. 10:e0122417.
   PubMed Web of Science ®Google Scholar
• Aslan A, Gurelik M, Cemek M, Buyukokuroglu M, Goksel HM, Eser O. 2012. Nimodipine can diminish oxidative stress in patients with severe head trauma. J Neurosurg Sci. 56:247–253.
   PubMed Web of Science ®Google Scholar
• Beutler E, Dubon O, Kelly BM. 1963. Improved method for the determination of blood glutathione. J Lab Clin Med. 61:882–888.
   PubMed Web of Science ®Google Scholar
• Birdane F, Cemek M, Birdane YO. 2007. Beneficial effects of Foeniculum vulgare on ethanol-induced acute gastric mucosal injury in rats. World J Gastroenterol. 13:607–611.
   PubMed Web of Science ®Google Scholar
• Caksen H, Ozkan M, Cemek M, Cemek F. 2014. Oxidant and antioxidant status in children with subacute sclerosing panencephalitis. J Child Neurol. 29:1448–1452.
   PubMed Web of Science ®Google Scholar
• Carari M, Corradini C, Elviri L. 2003. Direct HPLC analysis of quercetin and trans-resveratrol in red wine, grape, and winemaking byproducts. J Agric Food Chem. 51:5226–5229.
   PubMed Web of Science ®Google Scholar
• Cemek M, Enginar H, Karaca T, Unak P. 2006. In vivo radioprotective effects of Nigella sativa L oil and reduced glutathione against irradiation-induced oxidative injury and number of peripheral blood lymphocytes in rats. Photochem Photobiol. 82:1691–1696.
   PubMed Web of Science ®Google Scholar
• Cemek M, Yılmaz E, Büyükokuroğlu ME. 2010. Protective effect of Matricaria chamomilla on ethanol-induced acute gastric mucosal injury in rats. Pharm Biol. 48:757–763.
   PubMed Web of Science ®Google Scholar
• Choi E, Hwang H, Kim I. 2009. Protective effects of a polysaccharide from Hizikia fusiformis against ethanol toxicity in rats. Food Chem Toxicol. 47:134–139.
   PubMed Web of Science ®Google Scholar
• Ekström AM, Serafini M, Nyrén O, Wolk A, Bosetti C, Bellocco R. 2011. Dietary quercetin intake and risk of gastric cancer: results from a population-based study in Sweden. Ann Oncol. 22:438–443.
   PubMed Web of Science ®Google Scholar
• Ertuğ PU, Aydinoglu F, Goruroglu Ozturk O, Singirik E, Ögülener N. 2013. Comparative study of the quercetin, ascorbic acid, glutathione and superoxide dismutase for nitric oxide protecting effects in mouse gastric fundus. Eur J Pharmacol. 698:379–387.
   PubMed Web of Science ®Google Scholar
• Gemede HF, Haki GD, Beyene F, Woldegiorgis AZ, Rakshit SK. 2015. Proximate, mineral, and antinutrient compositions of indigenous Okra (Abelmoschus esculentus) pod accessions: implications for mineral bioavailability. Food Sci Nutr. 4:223–233.
   PubMed Web of Science ®Google Scholar
• Gungor ANC, Gencer M, Karaca T. 2014. The effect of hesperetin on ischemia-reperfusion injury in rat ovary. Arch Gynecol Obstet. 290:763–769.
   PubMed Web of Science ®Google Scholar
• Jain SK, McVie R, Duett J. 1989. Erythrocyte membrane lipid peroxidase and glycolylated hemoglobin in diabetes. Diabetes. 38:1539–1543.
   PubMed Web of Science ®Google Scholar
• Jarret RL, Wang ML, Levy IJ. 2011. Seed oil and fatty acid content in okra (Abelmoschus esculentus) and related species. J Agric Food Chem. 59:4019–4024.
   PubMed Web of Science ®Google Scholar
• Klipinska G, Arabski M, Wisniewska-Jarosinska M, Kobayashi T, Ohta-Drzewoski J, Blasiak J, Chojnacki J. 2006. Protection action of melatonin and quercetin against DNA damage induced by N-methyl-N-nitro-N-nitrosoguanidine in normal and Helicobacter pylori-infected gastric mucosa cells. Gastroenterol Pol. 13:247–251.
   Google Scholar
• Laine L, Weinstein WM. 1988. Histology of alcoholic hemorrhagic “gastritis”: a prospective evaluation. Gastroenterology. 94:1254–1262.
   PubMed Web of Science ®Google Scholar
• Lengsfeld C, Titgemeyer F, Faller G, Hensel A. 2004. Glycosylated compounds from okra inhibit adhesion of Helicobacter pylori to human gastric mucosa. J Agric Food Chem. 52:1495–1503.
   PubMed Web of Science ®Google Scholar
• Liju VB, Jeena K, Kuttan R. 2015. Gastroprotective activity of essential oils from turmeric and ginger. J Basic Clin Physiol Pharmacol. 26:95–103.
   PubMedGoogle Scholar
• Ngoc TH, Ngoc QN, Tran A. 2008. Hypolipidemic effect of extracts from Abelmoschus esculentus (Malvaceae) on tyloxapol-induced hyperlipidemia in mice. J Pharm Sci. 35:42–46.
   Google Scholar
• Omaye ST, Turnbull JD, Sauberlich HE. 1979. Selected methods for the determination of ascorbic acid in animal cells, tissues, and fluids. Methods Enzymol. 62:3–11.
   PubMedGoogle Scholar
• Sabitha V, Ramachandran S, Naveen KR. 2011. Antidiabetic and antihyperlipidemic potential of Abelmoschus esculentus Moench. in streptozotocin-induced diabetic rats. J Pharm Bioallied Sci. 3:397–402.
   PubMedGoogle Scholar
• Salga MS, Ali HM, Abdulla MA. 2012. Gastroprotective activity and mechanism of novel dichlorido-zinc(II)-4-(2-(5-methoxybenzylideneamino)ethyl)piperazin-1-iumphenolate complex on ethanol-induced gastric ulceration. Chem Biol Interact. 195:144–153.
   PubMed Web of Science ®Google Scholar
• Shrikant VJ, Kalyani AK, Urvashi VM, Sandesh RL, Payal DS, Heta GV, Ruchi BV, Bhavin AV, Gajanan GK. 2011. Alteration of gastric mucus secretion in rats treated with Abelmoschus esculentus seed mucilage. Der Pharmacia Lettre. 3:183–188.
   Google Scholar
• Shui G, Peng LL. 2004. An improved method for the analysis of major antioxidants of Hibiscus esculentus Linn. J Chromatogr A. 1048:17–24.
   PubMed Web of Science ®Google Scholar
• Sidahmed HMA, Hashim NM, Abdulla MA. 2015. Antisecretory, gastroprotective, antioxidant and anti-Helicobcter pylori activity of zerumbone from Zingiber Zerumbet (L.), Smith. PLoS One. 10:e0121060.
   PubMed Web of Science ®Google Scholar
• Suzuki J, Katoh N. 1990. A simple and cheap method for measuring serum vitamin A in cattle using only a spectrophotometer. Nippon Juigaku Zasshi. 52:1281–1283.
   PubMedGoogle Scholar
• Uner A, Sal E, Doğan M, Sanli FM, Acikgoz M, Cemek M, Peker E, Cagan E. 2010. Investigation of oxidant and antioxidant pathway changes in acute rheumatic fever. Acta Cardiol. 65:53–57.
   PubMed Web of Science ®Google Scholar
• Van Dam RM, Naidoo N, Landberg R. 2013. Dietary flavonoids and the development of type 2 diabetes and cardiovascular diseases: review of recent findings. Curr Opin Lipidol. 24:25–33.
   PubMed Web of Science ®Google Scholar
• Wang YZ, Cao YQ, Wu JN, Chen M, Cha XY. 2005. Expression of nitric oxide synthase in human gastric carcinoma and its relation to p53, PCNA. World J Gastroenterol. 11:46–50.
   PubMed Web of Science ®Google Scholar
• Winkler BS, Orselli SM, Rex TS. 1994. The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective. Free Radic Biol Med. 17:333–349.
   PubMed Web of Science ®Google Scholar
• Xia F, Zhong Y, Li M, Chang Q, Liao Y, Liu X, Pan R. 2015. Antioxidant and Anti-Fatigue Constituents of Okra. Nutrients. 7:8846–8858.
   PubMed Web of Science ®Google Scholar
• Yan XM, Joo MJ, Lim JC, Whang WK, Sim SS, Im C, Kim HR, Lee SY, Kim IK, Sohn UD. 2011. The effect of quercetin-3-O-β-D-glucuronopyranoside on indomethacin-induced gastric damage in rats via induction of mucus secretion and down-regulation of ICAM-1 expression. Arch Pharm Res. 34:1527–1534.
   PubMed Web of Science ®Google Scholar
• Yesilada E, Gürbüz I, Toker G. 2014. Anti-ulcerogenic activity and isolation of the active principles from Sambucus ebulus L. leaves. J Ethnopharmacol. 28:478–483.
   Web of Science ®Google Scholar